The febrile response to lipopolysaccharide is blocked in cyclooxygenase- 2(-/-), but not in cyclooxygenase-1(-/-) mice

Brain Research

Volumn 825, Issue 1-2, 1999, Pages 86-94

  Li, S ^a   Wang, Y ^a   Matsumura, K ^b   Ballou, L R ^a,d   Morham, S G ^c   Blatteis, C M ^b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b OSAKA BIOSCIENCE INSTITUTE   (Japan)

^c Myriad Genetics Laboratories Inc   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Brain; Endothelial cell; Endotoxin; Fever; Neuroimmunomodulation; Prostaglandin E2

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 1; PYROGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; CONTROLLED STUDY; CORE TEMPERATURE; ENDOTHELIUM CELL; ENZYME INDUCTION; FEVER; IMMUNOCYTOCHEMISTRY; IMMUNOMODULATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BLOTTING, SOUTHERN; BRAIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DINOPROSTONE; FEVER; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENOTYPE; ISOENZYMES; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROIMMUNOMODULATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 0033577548     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01225-1     Document Type: Article

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