An in vitro investigation into conformational aspects of gabapentin

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 5, 1999, Pages 715-721

  Bryans, Justin S ^a   Horwell, David C ^a   Ratcliffe, Giles S ^a   Receveur, Jean Marie ^a   Rubin, J Ronald ^b  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^b PFIZER INC   (United States)

Author keywords

Anticonvulsants; Molecular modelling; NMR; X ray crystal structures

Indexed keywords

4 AMINOBUTYRIC ACID DERIVATIVE; CYCLOHEXANE; GABAPENTIN;

ARTICLE; BINDING SITE; CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; X RAY CRYSTALLOGRAPHY;

ACETIC ACIDS; AMINES; ANTICONVULSANTS; CALCIUM CHANNELS; CRYSTALLOGRAPHY, X-RAY; CYCLOHEXANECARBOXYLIC ACIDS; GAMMA-AMINOBUTYRIC ACID; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; TEMPERATURE;

EID: 0033135064     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00023-1     Document Type: Article

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