Contribution of the intramolecular disulfide bridge to the folding stability of REIv, the variable domain of a human immunoglobulin κ light chain

Folding and Design

Volumn 1, Issue 6, 1996, Pages 431-440

  Frisch, Christian ^a,b   Kolmar, Harald ^a   Schmidt, Arno ^a   Kleemann, Gerd ^a,c   Reinhardt, Astrid ^a,b   Pohl, Ehmke ^a,d   Usón, Lsabel ^a   Schneider, Thomas R ^e   Fritz, Hans Joachim ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

^c UNIVERSITY OF BASEL   (Switzerland)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Italy)

Author keywords

Antibody engineering; Bence Jones protein; Disulfide bridge formation; Protein folding

Indexed keywords

DISULFIDE; IMMUNOGLOBULIN KAPPA CHAIN;

ARTICLE; CHEMISTRY; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; PROTEIN FOLDING;

DISULFIDES; HUMANS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; PROTEIN FOLDING;

EID: 0030320813     PISSN: 13590278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-0278(96)00059-4     Document Type: Article

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