메뉴 건너뛰기




Volumn 18, Issue 24, 1999, Pages 6983-6993

Direct inhibition of G1 cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation

Author keywords

Cell cycle; G1 cdks; MyoD; Myogenesis

Indexed keywords

CYCLIN D; CYCLIN D1; CYCLIN DEPENDENT KINASE; HELIX LOOP HELIX PROTEIN; HYBRID PROTEIN; MYOGENIC FACTOR;

EID: 0033572867     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.24.6983     Document Type: Article
Times cited : (90)

References (64)
  • 1
    • 0025239690 scopus 로고
    • Aberrant regulation of MyoD1 contributes to the partially defective myogenic phenotype of BC3H1 cells
    • published erratum appears in J. Cell Biol., 1990, 110, 2231
    • Brennan, T.J., Edmondson, D.G. and Olson, E.N. (1990) Aberrant regulation of MyoD1 contributes to the partially defective myogenic phenotype of BC3H1 cells (published erratum appears in J. Cell Biol., 1990, 110, 2231). J. Cell Biol, 110, 929-937.
    • (1990) J. Cell Biol , vol.110 , pp. 929-937
    • Brennan, T.J.1    Edmondson, D.G.2    Olson, E.N.3
  • 2
    • 0026534294 scopus 로고
    • Making muscle in mammals
    • Buckingham, M. (1992) Making muscle in mammals. Trends Genet., 8, 144-148.
    • (1992) Trends Genet. , vol.8 , pp. 144-148
    • Buckingham, M.1
  • 3
    • 0028178123 scopus 로고
    • The Caenorhabditis elegans MYOD homologue HLH-1 is essential for proper muscle function and complete morphogenesis
    • Chen, L., Krause, M., Sepanski, M. and Fire, A. (1994) The Caenorhabditis elegans MYOD homologue HLH-1 is essential for proper muscle function and complete morphogenesis. Development, 120, 1631-1641.
    • (1994) Development , vol.120 , pp. 1631-1641
    • Chen, L.1    Krause, M.2    Sepanski, M.3    Fire, A.4
  • 4
    • 0024429019 scopus 로고
    • Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
    • Chen, P.L., Scully, P., Shew, J.Y., Wang, J.Y. and Lee, W.H. (1989) Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell, 58, 1193-1198.
    • (1989) Cell , vol.58 , pp. 1193-1198
    • Chen, P.L.1    Scully, P.2    Shew, J.Y.3    Wang, J.Y.4    Lee, W.H.5
  • 9
    • 0030657477 scopus 로고    scopus 로고
    • A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase
    • Diehl, J.A. and Sherr, C.J. (1997) A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase. Mol. Cell. Biol., 17, 7362-7374.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 7362-7374
    • Diehl, J.A.1    Sherr, C.J.2
  • 10
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family proteins
    • Dyson, N. (1998) The regulation of E2F by pRB-family proteins. Genes Dev., 12, 2245-2262.
    • (1998) Genes Dev. , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 11
    • 0027502844 scopus 로고
    • Skeletal myogenesis: Genetics and embryology to the fore
    • Emerson, C.P.,Jr (1993) Skeletal myogenesis: genetics and embryology to the fore. Curr. Opin. Genet. Dev., 3, 265-274.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 265-274
    • Emerson C.P., Jr.1
  • 12
    • 0027229136 scopus 로고
    • Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
    • Ewen, M.E., Sluss, H.K., Sherr, C.J., Matsushime, H., Kato, J. and Livingston, D.M. (1993) Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell, 73, 487-497.
    • (1993) Cell , vol.73 , pp. 487-497
    • Ewen, M.E.1    Sluss, H.K.2    Sherr, C.J.3    Matsushime, H.4    Kato, J.5    Livingston, D.M.6
  • 13
    • 0028124463 scopus 로고
    • The two-hybrid system: An assay for protein-protein interactions
    • Fields, S. and Sternglanz, R. (1994) The two-hybrid system: an assay for protein-protein interactions. Trends Genet., 10, 286-292.
    • (1994) Trends Genet. , vol.10 , pp. 286-292
    • Fields, S.1    Sternglanz, R.2
  • 14
  • 15
    • 0000404279 scopus 로고
    • The rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection
    • Gorman, C.M., Merlino, G.T., Willingham, M.C., Pastan, I. and Howard, B.H. (1982) The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc. Natl Acad. Sci. USA, 79, 6777-6781.
    • (1982) Proc. Natl Acad. Sci. USA , vol.79 , pp. 6777-6781
    • Gorman, C.M.1    Merlino, G.T.2    Willingham, M.C.3    Pastan, I.4    Howard, B.H.5
  • 16
    • 0027499060 scopus 로고
    • Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
    • Gu, W., Schneider, J.W., Condorelli, G., Kaushal, S., Mahdavi, V. and Nadal-Ginard, B. (1993) Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell, 72, 309-324.
    • (1993) Cell , vol.72 , pp. 309-324
    • Gu, W.1    Schneider, J.W.2    Condorelli, G.3    Kaushal, S.4    Mahdavi, V.5    Nadal-Ginard, B.6
  • 18
    • 0027382336 scopus 로고
    • Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein
    • Helin, K., Harlow, E. and Fattaey, A. (1993) Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein. Mol. Cell. Biol., 13, 6501-6508.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6501-6508
    • Helin, K.1    Harlow, E.2    Fattaey, A.3
  • 20
    • 0026021882 scopus 로고
    • Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product
    • Kaelin, W.G.Jr, Pallas, D.C., DeCaprio, J.A., Kaye, F.J. and Livingston, D.M. (1991) Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell, 64, 521-532.
    • (1991) Cell , vol.64 , pp. 521-532
    • Kaelin W.G., Jr.1    Pallas, D.C.2    DeCaprio, J.A.3    Kaye, F.J.4    Livingston, D.M.5
  • 21
    • 0027288908 scopus 로고
    • Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
    • Kato, J., Matsushime, H., Hiebert, S.W., Ewen, M.E. and Sherr, C.J. (1993) Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev., 7, 331-342.
    • (1993) Genes Dev. , vol.7 , pp. 331-342
    • Kato, J.1    Matsushime, H.2    Hiebert, S.W.3    Ewen, M.E.4    Sherr, C.J.5
  • 22
    • 0028270189 scopus 로고
    • Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase
    • Kato, J.Y., Matsuoka, M., Strom, D.K. and Sherr, C.J. (1994) Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase. Mol. Cell. Biol., 14, 2713-2721.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2713-2721
    • Kato, J.Y.1    Matsuoka, M.2    Strom, D.K.3    Sherr, C.J.4
  • 23
    • 0025009110 scopus 로고
    • A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding
    • Kaye, F.J., Kratzke, R.A., Gerster, J.L. and Horowitz, J.M. (1990) A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding. Proc. Natl Acad. Sci. USA, 87, 6922-6926.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 6922-6926
    • Kaye, F.J.1    Kratzke, R.A.2    Gerster, J.L.3    Horowitz, J.M.4
  • 24
    • 12644284504 scopus 로고    scopus 로고
    • The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2
    • Kitagawa, M. et al. (1996) The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2. EMBO J., 15, 7060-7069.
    • (1996) EMBO J. , vol.15 , pp. 7060-7069
    • Kitagawa, M.1
  • 25
    • 0030849455 scopus 로고    scopus 로고
    • Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation
    • Knudsen, E.S. and Wang, J.Y. (1997) Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation. Mol. Cell. Biol., 17, 5771-5783.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5771-5783
    • Knudsen, E.S.1    Wang, J.Y.2
  • 27
    • 0028264474 scopus 로고
    • Wiring diagrams: Regulatory circuits and the control of skeletal myogenesis
    • Lassar, A. and Munsterberg, A. (1994) Wiring diagrams: regulatory circuits and the control of skeletal myogenesis. Curr. Opin. Cell Biol., 6, 432-442.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 432-442
    • Lassar, A.1    Munsterberg, A.2
  • 28
    • 0025808242 scopus 로고
    • Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo
    • Lassar, A.B., Davis, R.L., Wright, W.E., Kadesch, T, Murre, C., Voronova, A., Baltimore, D. and Weintraub, H. (1991) Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo. Cell, 66, 305-315.
    • (1991) Cell , vol.66 , pp. 305-315
    • Lassar, A.B.1    Davis, R.L.2    Wright, W.E.3    Kadesch, T.4    Murre, C.5    Voronova, A.6    Baltimore, D.7    Weintraub, H.8
  • 29
    • 0028032677 scopus 로고
    • Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal
    • Lassar, A.B., Skapek, S.X. and Novitch, B. (1994) Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Curr. Opin. Cell Biol., 6, 788-794.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 788-794
    • Lassar, A.B.1    Skapek, S.X.2    Novitch, B.3
  • 30
    • 0028988158 scopus 로고
    • K1P2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
    • K1P2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev., 9, 639-649.
    • (1995) Genes Dev. , vol.9 , pp. 639-649
    • Lee, M.H.1    Reynisdottir, I.2    Massague, J.3
  • 31
    • 0024698488 scopus 로고
    • An avian muscle factor related to MyoD1 activates muscle-specific promoters in nonmuscle cells of different germ-layer origin and in BrdU-treated myoblasts
    • Lin, Z.Y., Dechesne, C.A., Eldridge, J. and Paterson, B.M. (1989) An avian muscle factor related to MyoD1 activates muscle-specific promoters in nonmuscle cells of different germ-layer origin and in BrdU-treated myoblasts. Genes Dev., 3, 986-996.
    • (1989) Genes Dev. , vol.3 , pp. 986-996
    • Lin, Z.Y.1    Dechesne, C.A.2    Eldridge, J.3    Paterson, B.M.4
  • 32
    • 0031917781 scopus 로고    scopus 로고
    • Cell cycle-regulated expression of the muscle determination factor Myf5 in proliferating myoblasts
    • Lindon, C., Montarras, D. and Pinset, C. (1998) Cell cycle-regulated expression of the muscle determination factor Myf5 in proliferating myoblasts. J. Cell Biol., 140, 111-118.
    • (1998) J. Cell Biol. , vol.140 , pp. 111-118
    • Lindon, C.1    Montarras, D.2    Pinset, C.3
  • 34
    • 0029954208 scopus 로고    scopus 로고
    • MyoD is required for myogenic stem cell function in adult skeletal muscle
    • Megeney, L.A., Kablar, B., Garrett, K., Anderson, J.E. and Rudnicki, M.A. (1996) MyoD is required for myogenic stem cell function in adult skeletal muscle. Genes Dev., 10, 1173-1183.
    • (1996) Genes Dev. , vol.10 , pp. 1173-1183
    • Megeney, L.A.1    Kablar, B.2    Garrett, K.3    Anderson, J.E.4    Rudnicki, M.A.5
  • 35
    • 0028181760 scopus 로고
    • 1 kinase activity for cdk6, a novel cyclin D partner
    • 1 kinase activity for cdk6, a novel cyclin D partner. Mol. Cell. Biol., 14, 2077-2086.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2077-2086
    • Meyerson, M.1    Harlow, E.2
  • 37
    • 0025130535 scopus 로고
    • Myogenic programs of mouse muscle cell lines: Expression of myosin heavy chain isoforms, MyoD1 and myogenin
    • Miller, J.B. (1990) Myogenic programs of mouse muscle cell lines: expression of myosin heavy chain isoforms, MyoD1 and myogenin. J. Cell Biol., 111, 1149-1159.
    • (1990) J. Cell Biol. , vol.111 , pp. 1149-1159
    • Miller, J.B.1
  • 38
    • 0024431684 scopus 로고
    • In vivo footprinting of a muscle specific enhancer by ligation mediated PCR
    • published erratum appears in Science, 1990, 248, 802
    • Mueller, P.R. and Wold, B. (1989) In vivo footprinting of a muscle specific enhancer by ligation mediated PCR (published erratum appears in Science, 1990, 248, 802). Science, 246, 780-786.
    • (1989) Science , vol.246 , pp. 780-786
    • Mueller, P.R.1    Wold, B.2
  • 40
    • 0028033270 scopus 로고
    • Mutations and altered expression of p16INK4 in human cancer
    • Okamoto, A. et al (1994) Mutations and altered expression of p16INK4 in human cancer. Proc. Natl Acad. Sci. USA, 91, 11045-11049.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 11045-11049
    • Okamoto, A.1
  • 41
    • 0026481962 scopus 로고
    • Interplay between proliferation and differentiation within the myogenic lineage
    • Olson, E.N. (1992) Interplay between proliferation and differentiation within the myogenic lineage. Dev. Biol., 154, 261-272.
    • (1992) Dev. Biol. , vol.154 , pp. 261-272
    • Olson, E.N.1
  • 43
    • 0025762130 scopus 로고
    • The Drosophila homologue of vertebrate myogenic-determination genes encodes a transiently expressed nuclear protein marking primary myogenic cells
    • Paterson, B.M., Walldorf, U., Eldridge, J., Dubendorfer, A., Frasch, M. and Gehring, W.J. (1991) The Drosophila homologue of vertebrate myogenic-determination genes encodes a transiently expressed nuclear protein marking primary myogenic cells. Proc. Natl Acad. Sci. USA, 88, 3782-3786.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 3782-3786
    • Paterson, B.M.1    Walldorf, U.2    Eldridge, J.3    Dubendorfer, A.4    Frasch, M.5    Gehring, W.J.6
  • 46
    • 0032937751 scopus 로고    scopus 로고
    • Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia
    • Rane, S.G., Dubus, P., Mettus, R.V., Galbreath, E.J., Boden, G., Reddy, E.P. and Barbacid, M. (1999) Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia. Nature Genet., 22, 44-52.
    • (1999) Nature Genet. , vol.22 , pp. 44-52
    • Rane, S.G.1    Dubus, P.2    Mettus, R.V.3    Galbreath, E.J.4    Boden, G.5    Reddy, E.P.6    Barbacid, M.7
  • 47
    • 0028145332 scopus 로고
    • Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators
    • Rao, S.S., Chu, C. and Kohtz, D.S. (1994) Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators. Mol. Cell. Biol., 14, 5259-5267.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5259-5267
    • Rao, S.S.1    Chu, C.2    Kohtz, D.S.3
  • 48
    • 0029257376 scopus 로고
    • The MyoD family of transcription factors and skeletal myogenesis
    • Rudnicki, M.A. and Jaenisch, R. (1995) The MyoD family of transcription factors and skeletal myogenesis. BioEssays, 17, 203-209.
    • (1995) BioEssays , vol.17 , pp. 203-209
    • Rudnicki, M.A.1    Jaenisch, R.2
  • 51
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano, M., Hannon, G.J. and Beach, D. (1993) A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature, 366, 704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 53
    • 0027141375 scopus 로고
    • Dimerization specificity of myogenic helix-loop-helix DNA-binding factors directed by nonconserved hydrophilic residues
    • Shirakata, M., Friedman, F.K., Wei, Q. and Paterson, B.M. (1993) Dimerization specificity of myogenic helix-loop-helix DNA-binding factors directed by nonconserved hydrophilic residues. Genes Dev., 7, 2456-2470.
    • (1993) Genes Dev. , vol.7 , pp. 2456-2470
    • Shirakata, M.1    Friedman, F.K.2    Wei, Q.3    Paterson, B.M.4
  • 54
    • 0028928036 scopus 로고
    • Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase
    • Skapek, S.X., Rhee, J., Spicer, D.B. and Lassar, A.B. (1995) Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase. Science, 267, 1022-1024.
    • (1995) Science , vol.267 , pp. 1022-1024
    • Skapek, S.X.1    Rhee, J.2    Spicer, D.B.3    Lassar, A.B.4
  • 55
    • 0029985115 scopus 로고    scopus 로고
    • Cyclin-mediated inhibition of muscle gene expression via a mechanism that is independent of pRB hyperphosphorylation
    • Skapek, S.X., Rhee, J., Kim, P.S., Novitch, B.G. and Lassar, A.B. (1996) Cyclin-mediated inhibition of muscle gene expression via a mechanism that is independent of pRB hyperphosphorylation. Mol. Cell. Biol., 16, 7043-7053.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 7043-7053
    • Skapek, S.X.1    Rhee, J.2    Kim, P.S.3    Novitch, B.G.4    Lassar, A.B.5
  • 56
    • 0025277030 scopus 로고
    • Cell proliferation inhibited by MyoD1 independently of myogenic differentiation
    • Sorrentino, V., Pepperkok, R., Davis, R.L., Ansorge, W. and Philipson, L. (1990) Cell proliferation inhibited by MyoD1 independently of myogenic differentiation. Nature, 345, 813-815.
    • (1990) Nature , vol.345 , pp. 813-815
    • Sorrentino, V.1    Pepperkok, R.2    Davis, R.L.3    Ansorge, W.4    Philipson, L.5
  • 57
    • 0024294014 scopus 로고
    • MyoD1: A nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblasts
    • Tapscott, S.J., Davis, R.L., Thayer, M.J., Cheng, P.F., Weintraub, H. and Lassar, A.B. (1988) MyoD1: a nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblasts. Science, 242, 405-411.
    • (1988) Science , vol.242 , pp. 405-411
    • Tapscott, S.J.1    Davis, R.L.2    Thayer, M.J.3    Cheng, P.F.4    Weintraub, H.5    Lassar, A.B.6
  • 58
    • 0029758791 scopus 로고    scopus 로고
    • E2F1 inhibition of transcription activation by myogenic basic helix-loop-helix regulators
    • Wang, J., Huang, Q., Tang, W. and Nadal-Ginard, B. (1996) E2F1 inhibition of transcription activation by myogenic basic helix-loop-helix regulators. J. Cell Biochem., 62, 405-410.
    • (1996) J. Cell Biochem. , vol.62 , pp. 405-410
    • Wang, J.1    Huang, Q.2    Tang, W.3    Nadal-Ginard, B.4
  • 59
    • 0027738464 scopus 로고
    • The MyoD family and myogenesis: Redundancy, networks and thresholds
    • Weintraub, H. (1993) The MyoD family and myogenesis: redundancy, networks and thresholds. Cell. 75, 1241-1244.
    • (1993) Cell , vol.75 , pp. 1241-1244
    • Weintraub, H.1
  • 60
    • 0033564139 scopus 로고    scopus 로고
    • The transition from proliferation to differentiation is delayed in satellite cells from mice lacking MyoD
    • Yablonka-Reuveni, Z., Rudnicki, M.A., Rivera, A.J., Primig, M., Anderson, J.E. and Natanson, P. (1999) The transition from proliferation to differentiation is delayed in satellite cells from mice lacking MyoD. Dev. Biol., 210, 440-455.
    • (1999) Dev. Biol. , vol.210 , pp. 440-455
    • Yablonka-Reuveni, Z.1    Rudnicki, M.A.2    Rivera, A.J.3    Primig, M.4    Anderson, J.E.5    Natanson, P.6
  • 61
    • 0030955563 scopus 로고    scopus 로고
    • Kip2 results in increased apoptosis and delayed differentiation during mouse development
    • Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev., 11, 973-983.
    • (1997) Genes Dev. , vol.11 , pp. 973-983
    • Yan, Y.1    Frisen, J.2    Lee, M.H.3    Massague, J.4    Barbacid, M.5
  • 62
    • 0028169236 scopus 로고
    • P21-containing cyclin kinases exist in both active and inactive states
    • Zhang, H., Hannon, G.J. and Beach, D. (1994) p21-containing cyclin kinases exist in both active and inactive states. Genes Dev., 8, 1750-1758.
    • (1994) Genes Dev. , vol.8 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.J.2    Beach, D.3
  • 63
    • 0033558347 scopus 로고    scopus 로고
    • Coupling of the cell cycle and myogenesis through the cyclin D1-dependent interaction of MyoD with cdk4
    • Zhang, J.-M., Wei, Q., Zhao, X. and Paterson, B.M. (1999) Coupling of the cell cycle and myogenesis through the cyclin D1-dependent interaction of MyoD with cdk4. EMBO J., 18, 926-933.
    • (1999) EMBO J. , vol.18 , pp. 926-933
    • Zhang, J.-M.1    Wei, Q.2    Zhao, X.3    Paterson, B.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.