Resistance to pseudorabies virus infection in transgenic mice expressing the chimeric transgene that represses the immediate-early gene transcription

Virology

Volumn 262, Issue 1, 1999, Pages 72-78

  Ono, Etsuro ^a   Tasaki, Takafumi ^a   Kobayashi, Tsutomu ^a   Taharaguchi, Satoshi ^a   Nikami, Hideki ^a   Miyoshi, Ichiro ^b   Kasai, Noriyuki ^b   Arikawa, Jiro ^c   Kida, Hiroshi ^d   Shimizu, Yukio ^e  

^a HOKKAIDO UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

^e Kyoto Biken Laboratories   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ETOPOSIDE; HYBRID PROTEIN; IMMEDIATE EARLY PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING; GENE EXPRESSION; GENETIC TRANSCRIPTION; HERPES SIMPLEX VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PSEUDORABIES HERPETOVIRUS; TRANSCRIPTION REGULATION; TRANSGENE; TRANSGENIC MOUSE; VIROGENESIS; VIRUS REPLICATION; VIRUS RESISTANCE;

ANIMALIA; DNA VIRUSES; HERPES; HERPETOVIRUS; HUMAN HERPESVIRUS 1; MUS MUSCULUS; SUID HERPESVIRUS 1;

EID: 0033568091     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.9899     Document Type: Article

References (33)

1. Baltimore D. Intracellular immunization. Nature. 335:1988;395-396.
2. Cai W., Astor T. L., Liptak L. M., Cho C., Coen D. M., Schaffer P. A. The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency. J. Virol. 67:1993;7501-7512.
3. Chen X.-Z., Yun J. S., Wagner T. E. Enhanced viral resistance in transgenic mice expressing the human beta 1 interferon. J. Virol. 62:1988;3883-3887.
4. Cheung A. K. DNA nucleotide sequence analysis of the immediate-early gene of pseudorabies virus. Nucleic Acids Res. 17:1989;4637-4646.
5. Cheung A. K. Cloning of the latency gene and the early protein 0 gene of pseudorabies virus. J. Virol. 65:1991;5260-5271.
6. Cheung A. K. Latency characteristics of an EP0 and LLT mutant of pseudorabies virus. J. Vet. Diag. Invest. 8:1996;112-115.
7. Cheung A. K., Fang J., Wesley R. D. Characterization of a pseudorabies virus that defective in the early protein 0 and latency genes. Am. J. Vet. Res. 55:1994;1710-1716.
8. Hogan B., Constantini F., Kacy E. Manipulating the Mouse Embryo: A Laboratory Manual. 1986;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
9. Hug H., Costas M., Staeheli P., Aebi M., Weissman C. Organization of the murine Mx gene and characterization of its interferon- and virus-inducible promoter. Mol. Cell. Biol. 8:1988;3065-3079.
10. Ihara S., Feldman L., Watanabe S., Ben-Porat T. Characterization of the immediate-early functions of pseudorabies virus. Virology. 131:1983;437-454.
11. Kida H., Brown L. E., Webster R. G. Biological activity of monoclonal antibodies to operationally defined antigenic regions on the heamagglutining molecule of A/Seal/Massachusetts/1/80 (H7N7) influenza virus. Virology. 122:1982;38-47.
12. Kit S. Pseudorabies virus. Webster R. G., Granoff A. Encyclopedia of Virology. 1994;1173-1179 Academic Press, London.
13. Konkel D. A., Tilghman S. M., Leder P. The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) site. Cell. 15:1978;1125-1132.
14. Leib D. A., Coen D. M., Bogard C. L., Hicks K. A., Yager D. R., Knipe D. M., Tyler K. L., Schaffer P. A. Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. J. Virol. 63:1989;759-768.
15. McLean C., Buckmaster A., Hancock D., Buchan A., Fuller A., Minson T. Monoclonal antibodies to three nonglycosylated antigens of herpes simplex virus type 2. J. Gen. Virol. 63:1982;297-305.
16. Mitchell W. J., De Santo R. J., Zhang S.-D., Odenwald W. F., Arnheiter H. Herpes simplex virus pathogenesis in transgenic mice is altered by the homeodomain protein Hox 1.3. J. Virol. 67:1993;4484-4491.
17. Ono E., Sakoda Y., Taharaguchi S., Watanabe S., Tonomura N., Kida H., Shimizu Y. Inhibition of pseudorabies virus replication by a chimeric trans-gene product repressing transcription of the immediate-early gene. Virology. 210:1995;128-140.
18. Ono E., Taharaguchi S., Watanabe S., Nikami H., Shimizu Y., Kida H. Suppression of pseudorabies virus replication by a mutant form of immediate-early protein IE180 repressing the viral gene transcription. Vet. Microbiol. 60:1998a;107-117.
19. Ono E., Watanabe S., Nikami H., Tasaki T., Kida H. Pseudorabies virus (PRV) early protein 0 activates PRV gene transcription in combination with the immediate-early protein IE180 and enhances the infectivity of PRV genomic DNA. Vet. Microbiol. 63:1998b;99-107.
20. Onodera T., Yoshihara K., Suzuki T., Tsuda T., Ikeda T., Awaya A., Kobayashi H., Yukawa M. Resistance to pseudorabies virus with enhanced interferon production and natural killer cell activity in mice treated with serum thymic factor. Microbiol. Immunol. 38:1994;47-53.
21. Roizman B. Herpesviridae: A brief introduction. Fields B. N., Knipe D. M. Fields' Virology. 1990;1787-1793 Raven Press, New York.
22. Schreiber E., Matthias P., Muller M. M., Schaffner W. Rapid detection of octamer binding proteins with "mini-extracts," prepared from a small number of cells. Nucleic Acids Res. 17:1989.
23. Smith C. A., DeLuca N. A. Transdominant inhibition of herpes simplex virus growth in transgenic mice. Virology. 191:1992;581-588.
24. Southern E. M. Detection of specific sequence among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:1975;503-517.
25. Spatz S. J., Nordby E. C., Weber P. C. Mutational analysis of ICP0R, a transrepressor protein created by alternative splicing of the ICP0 gene of herpes simplex virus type 1. J. Virol. 70:1996;7360-7370.
26. Taharaguchi S., Inoue H., Ono E., Kida H., Yamada S., Shimizu Y. Mapping of transcriptional regulatory domains of pseudorabies virus immediate-early protein. Arch. Virol. 137:1994;289-302.
27. Tonomura N., Ono E., Shimizu Y., Kida H. Negative regulation of immediate-early gene expression of pseudorabies virus by interferon-α Vet. Microbiol. 53:1996;271-281.
28. Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some application. Proc. Natl. Acad. Sci. USA. 76:1979;4350-4354.
29. Watanabe S., Ono E., Shimizu Y., Kida H. Pseudorabies virus early protein 0 transactivates the viral gene promoters. J. Gen. Virol. 76:1995;2881-2885.
30. Watanabe S., Ono E., Shimizu Y., Kida H. Mapping of transregulatory domains of pseudorabies virus early protein 0 and identification of its dominant-negative mutant. Arch. Virol. 141:1996;1001-1009.
31. Wilkie T. M., Brinster R. L., Palmiter R. D. Germline and somatic mosaicism in transgenic mice. Dev. Biol. 118:1986;9-18.
32. Yamamura K., Kikutani H., Takahashi N., Toda T., Akira S., Kawai K., Fukuchi K., Kumahara Y., Honjo T., Kishimoto T. Introduction of human gamma 1 immunoglobulin genes into fertilized mouse eggs. J. Biochem. 96:1984;357-363.
33. Zhu X., Chen J., Young C. S. H., Silverstein S. Reactivation of latent herpes simplex virus by adenovirus recombinants encoding mutant IE-0 gene products. J. Virol. 64:1990;4489-4498.