The substrate binding site of human liver cytochrome P450 2C9: An NMR study

Biochemistry

Volumn 36, Issue 42, 1997, Pages 12672-12682

  Poli Scaife, Sonia ^a   Attias, Roger ^a   Dansette, Patrick M ^a   Mansuy, Daniel ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOCHROME P450; DICLOFENAC; LAURIC ACID; LIVER ENZYME; NONSTEROID ANTIINFLAMMATORY AGENT; RECOMBINANT PROTEIN; SULFAPHENAZOLE; TIENILIC ACID;

ARTICLE; DRUG METABOLISM; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SUBSTRATE; HUMAN; LIVER METABOLISM; MOLECULAR MODEL; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TEMPERATURE DEPENDENCE; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BINDING SITES; CYTOCHROME P-450 ENZYME SYSTEM; DICLOFENAC; HUMANS; ISOMERISM; KINETICS; LAURIC ACIDS; MICROSOMES, LIVER; MODELS, CHEMICAL; MODELS, MOLECULAR; NADPH-FERRIHEMOPROTEIN REDUCTASE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; RATS; SPECTROPHOTOMETRY; STEROID 16-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES; SULFAPHENAZOLE; TICRYNAFEN;

EID: 0030687597     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970527x     Document Type: Article

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