T cell immunity induced by allogeneic microglia in relation to neuronal retina transplantation

Journal of Immunology

Volumn 162, Issue 8, 1999, Pages 4482-4489

  Ma, Naili ^a   Streilein, J Wayne ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSFORMING GROWTH FACTOR BETA2;

ALLOIMMUNITY; ANIMAL CELL; ARTICLE; BRAIN TRANSPLANTATION; CELLULAR IMMUNITY; CYTOKINE RELEASE; GRAFT REJECTION; HYPERSENSITIVITY; IMMUNOGENICITY; LEUKOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MICROGLIA; MOUSE; NERVE TRANSPLANTATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RETINA NERVE CELL;

ANIMALS; ANTERIOR CHAMBER; ANTIGEN-PRESENTING CELLS; ANTIGENS, SURFACE; ASCITIC FLUID; CELLS, CULTURED; CYTOKINES; HYPERSENSITIVITY, DELAYED; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-12; ISOANTIGENS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICROGLIA; NEURONS; RETINA; T-LYMPHOCYTE SUBSETS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0033561725     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Hickey, W. F., and H. Kimura. 1988. Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science 239:290.
2. Perry, V. H., and S. Gordon. 1988. Macrophages and microglia in the nervous system. Trends Neurosci. 11:273.
3. Streit, W. J., M. B. Graeber, and G. W. Kreutzberg. 1988. Functional plasticity of microglia: a review. Glia 1:301.
4. Lassmann, H., M. Schmied, K. Vass, and W. F. Mickey. 1993. Bone marrow derived elements and resident microglia in brain inflammation. Glia 7:19.
5. Ling, E. A., and W. C. Wong. 1993. The origin and nature of ramified and ameboid microglia: a historical review and current concepts. Glia 7:9.
6. Ling, E. A. 1994. Monocytic origin of ramified microglia in the corpus callosum in postnatal rat. Neuropathol. Appl. Neurobiol. 20:182.
7. Ulvestad, E., K. Williams, R. Bjerkvig, K. Tiekotter, J. Antel, and R. Matre. 1994. Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells. J. Leukocyte Biol. 56:732.
8. Lazarov-Spiegler, O., A. S. Solomon, A. B. Zeev-Brann, D. L. Hirschberg, V. Lavie, and M. Schwartz. 1996. Transplantation of activated macrophages overcomes central nervous system regrowth failure. FASEB J. 10:1296.
9. Perry, V. H., P. B. Andersson, and S. Gordon. 1993. Macrophages and inflammation in the central nervous system. Trends Neurosci. 16:268.
10. Gehrmann, J., Y. Matsumoto, and G. W. Kreutzberg. 1995. Microglia: intrinsic immuneffector cell of the brain. Brain Res. Rev. 20:269.
11. Kreutzberg, G. W. 1996. Microglia, a sensor for pathological events in the CNS. Trends Neurosci. 19:312.
12. Ford, A. L., E. Foulcher, F. A. Lemckert, and J. D. Sedgwick. 1996. Microglia induce CD4 T lymphocyte final effector function and death. J. Exp. Med. 184: 1737.
13. Aloisi, F., F. Ria, G. Penna, and L. Adorini. 1998. Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation. J. Immunol. 159:1604.
14. Sedgwick, J. D, A. L. Ford, E. Foulcher, and R. Airriess. 1997. Central nervous system microglial cell activation and proliferation follows direct interaction with tissue-infiltrating T cell blasts. J. Immunol. 160:5320.
15. Benveniste, E. N. 1994. Cytokine circuits in brain. Implications for AIDS dementia complex. Res. Publ. Assoc. Res. Nerv. Ment. Dis. 72:71.
16. Merrill, J. E., and E. N. Benveniste. 1996. Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci. 19:331.
17. Aloisi, F., G. Penna, J. Cerase, B. M. Iglesias, and L. Adorini. 1997. IL-12 production by central nervous system microglia is inhibited by astrocytes. J. Immunol. 159:1604.
18. Steinmuller, D. 1967. Immunization with skin isografts taken from tolerant mice. Science 158:127.
19. Steinmuller, D., and E. A. Hart. 1971. Passenger leukocytes and induction of allograft immunity. Transplant. Proc. 3:673.
20. Stuart, F. P., E. Bastien, A. Holler, F. W. Fitch, and W. L. Elkins. 1971. Role of passenger leukocytes in the rejection of renal allografts. Transplant. Proc. 3:461.
21. Wachtel, S. S., and W. K. Silvers. 1972. The role of passenger leukocytes in the anomalous survival of neonatal skin grafts in mice. J. Exp. Med. 135:388.
22. Billingham, R. E. 1971. The passenger cell concept in transplantation immunology. Cell. Immunol. 2:1.
23. Jiang, L. Q., and J. W. Streilein. 1991. Immune responses elicited by transplantation and tissue-restricted antigens expressed on retinal tissues implanted sub-conjunctivally. Transplantation 52:513.
24. Jiang, L. Q., M. Jorquera, J. W. Streilein, and M. Ishioka. 1995. Unconventional rejection of neural retinal allografts implanted into the immunologically privileged site of the eye. Transplantation 59:1201.
25. Jiang, L. Q., M. Jorquera, and J. W. Streilein. 1993. Subretinal space and vitreous cavity as immunologically privileged sites for retinal allografts. Invest. Ophthalmol. Visual Sci. 34:3347.
26. Ma, N., and J. W. Streilein. 1998. Microglia, as passenger leukocytes, contribute to the fate of intraocular neuronal retinal grafts. Invest. Ophthalmol. Visual Sci. 39:2384.
27. Sreit, W. J., and G. W. Kreutzberg. 1987. Lectin binding by resting and reactive microglia. J. Neurocytol. 16:249.
28. Roque, R. S., and R. B. Caldwell. 1993. Isolation and culture of retinal microglia Curr. Eye Res. 12:285.
29. Takeuchi, M., M. M. Kosiewicz, P, Alard, and J. W. Streilein. 1997. On the mechanisms by which transforming growth factor-β2 alters antigen-presenting abilities of macrophages on T cell activation. Eur. J. Immunol. 27:1648.
30. Takeuchi, M., P. Alard, and J. W. Streilein. 1998. TGF-β promotes immune deviation by altering accessory singals of antigen-presenting cells. J. Immunol. 160:1589.
31. + T lymphocytes in the central nervous system. Clin. Exp. Immunol. 98:313.
32. Williams, K., N. Dooley, E. Ulvestad, B. Becher, and J. P. Antel. 1996. IL-10 production by adult human derived microglial cells. Neurochem. Int. 29:55.
33. Constantinescu, C. S., K. Frei, M. Wysocka, G. Trinchieri, U. Malipiero, A. Rostami, and A. Fontana. 1996. Astrocyte and microglia produce interleukin-12 p40. Ann. NY Acad. Sci. 795:328.
34. Constam, D. B., J. Philipp, U. V. Malipiero, P. T. Dijke, M. Schachner, and A. Fontana. 1992. Differential expression of transforming growth factor-β1, -β2 and -β3 by glioblastoma cells, astrocytes, and microglia. J. Immunol. 148:1404.
35. Okamoto, S., Y. Hara, and J. W. Streilein. 1995. Induction of anterior chamber-associated immune deviation with lymphoreticular allogeneic cells. Transplantation 59:377.
36. 2 and cyclic AMP-elevating agents. J. Neuroimmunol. 72:83.
37. Desmedt, M., P. Rottiers, H. Dooms, W. Fiers, and J. Grooten. 1998. Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses. J. Immunol. 160:5300.
38. Nguyen, V. T., W. S. Walker, and E. N. Benveniste. 1998. Post-transcriptional inhibition of CD40 gene expression in microglia by transforming growth factor-β. Eur. J. Immunol. 28:2537.
39. Dallman, M. J. 1995. Cytokines and transplantation: Th1/Th2 regulation of the immune response to solid organ transplants in the adult. Curr. Opin. Immunol. 7:632.
40. Strom, T. B., P. Roy-Chaudhury, R. Manfro, X. X. Zheng, P. W. Nickerson, K. Wood, and A. Bushell. 1996. The Th1/Th2 paradigm and the allograft response. Curr. Opin. Immunol. 8:688.
41. Rao, K., R. D. Lund, H. W. Kunz, and T. J. Gill. 1989. The role of MHC-and non-MHC antigens in the rejection of intracerebral allogeneic neural grafts Transplantation 336:613.
42. Perry, V. H., and R. D. Lund. 1989. Microglia in retinae transplanted to the central nervous system. Neuroscience 31:453.
43. Banerjee, R., and R. D. Lund. 1992. A role for microglia in the maintenance of photoreceptors in retinal transplants lacking pigment epithelium. J. Neurocytol. 21:235.
44. Banerjee, R., R. D. Lund, and J. D. Radel. 1993. Anatomical and functional consequences of induced rejection of intracranial retinal transplants. Neuroscience 56:939.
45. Broadwell, R. D., B. J. Baker, P. S. Ebert, and W. F. Hickey. 1994. Allografts of CNS tissue possess a blood-brain barrier. III. Neuropathological, methodological, and immunological considerations. Microsc. Res. Tech. 27:471.
46. Mokry, J. 1992. Transplantation immunology of the brain as privileged site for neural grafting. Sb. Ved. Pr. Lek. Fak. Karlovy Univ. 307.