Increased NPY activity in the PVN contributes to food-restriction induced reductions in blood pressure in aortic coarctation hypertensive rats

Brain Research

Volumn 821, Issue 2, 1999, Pages 263-269

  Vanness, J Mark ^a   DeMaria, Jamie E ^a   Overton, J Michael ^a  

^a Food Exercise Sci   (United States)

Author keywords

D Tyr27,36 Thr32 NPY((27 36)); D Trp32 NPY((1 36)); Energy balance; Hypertension; Hypothalamus

Indexed keywords

NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR;

ANIMAL MODEL; AORTA COARCTATION; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CALORIC INTAKE; CONTROLLED STUDY; DIET RESTRICTION; HEART RATE; HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; REFEEDING; THALAMUS MIDLINE NUCLEUS;

ANIMALS; AORTIC COARCTATION; BEHAVIOR, ANIMAL; BLOOD PRESSURE; BODY WEIGHT; ENERGY INTAKE; ENERGY METABOLISM; HEART RATE; HYPERTENSION; MALE; MICROINJECTIONS; NEUROPEPTIDE Y; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0033550879     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01058-6     Document Type: Article

References (41)

1. Aguirre J.A., Fuxe K., Agnati L.F., von Euler G. Centrally injected neuropeptide Y (13-36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1-36) in the awake male rat. Neurosci. Lett. 118:1990;5-8.
2. Balasubramaniam A. Neuropeptide Y family of hormones: receptor subtypes and antagonists. Peptides. 18:1997;445-457.
3. Balasubramaniam A., Sheriff S., Johnson M.E., Prabhakaran M., Huang Y., Fischer J.E., Chance W.T. [D-Trp32] Neuropeptide Y: a competitive antagonist of NPY in rat hypothalamus. J. Med. Chem. 37:1994;811-815.
4. Beck B., Jhanwar-Uniyal M., Burlet A., Chapleur-Chateau M., Leibowitz S.F., Burlet C. Rapid and localized alterations of neuropeptide Y in discrete hypothalamic nuclei with feeding status. Brain Res. 528:1990;245-249.
5. Billington C.J., Briggs J.E., Harker S., Grace M., Levine A.S. Neuropeptide Y in hypothalamic paraventricular nucleus: a center coordinating energy metabolism. Am. J. Physiol. 266:1994;R1765-70.
6. Caro J.F., Sinha M.K., Kolaczynski J.W., Zhang P.L., Considine R.V. Leptin: the tale of an obesity gene. Diabetes. 45:1996;1455-1462.
7. Casto R.M., VanNess J.M., Overton J.M. Effects of central leptin administration on blood pressure in normotensive rats. Neurosci. Lett. 246:1998;29-32.
8. Egawa M., Yoshimatsu H., Bray G.A. Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats. Am. J. Physiol. 260:1991;R328-R334.
9. Elmquist J.K., Ahima R.S., Elias C.F., Flier J.S., Saper C.B. Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proc. Natl. Acad. Sci. USA. 95:1998;741-746.
10. Elmquist J.K., Ahima R.S., Maratos-Flier E., Flier J.S., Saper C.B. Leptin activates neurons in ventrobasal hypothalamus and brainstem. Endocrinology. 138:1997;839-842.
11. Ernsberger P., Nelson D.O. Effects of fasting and refeeding on blood pressure are determined by nutritional state, not by body weight change. Am. J. Hypertens. 1:1988;153S-157S.
12. Flier J.S., Maratos-Flier E. Obesity and the hypothalamus: novel peptides for new pathways. Cell. 92:1998;437-440.
13. Gerald C., Walker M.W., Criscione L., Gustafson E.L., Batzl-Hartmann C., Smith K.E., Vaysse P., Durkin M.M., Laz T.M., Linemeyer D.L., Schaffhauser A.O., Whitebread S., Hofbauer K.G., Taber R.I., Branchek T.A., Weinshank R.L. A receptor subtype involved in neuropeptide-Y-induced food intake. Nature. 382:1996;168-171.
14. Harfstrand A. Intraventricular administration of neuropeptide Y (NPY) induces hypotension, bradycardia and bradypnea in the awake unrestrained male rat. Counteraction by NPY-induced feeding behaviour. Acta Physiol. Scand. 128:1986;121-123.
15. Harland D., Bennett T., Gardiner S.M. Cardiovascular actions of neuropeptide Y in the hypothalamic paraventricular nucleus of conscious Long Evans and Brattleboro rats. Neurosci. Lett. 85:1988;239-243.
16. Haynes W.G., Sivitz W.I., Morgan D.A., Walsh S.A., Mark A.L. Sympathetic and cardiorenal actions of leptin. Hypertension. 30:1997;619-623.
17. Heinrichs S.C., Menzaghi F., Koob G.F. Neuropeptide Y-induced feeding and its control. Vitam Horm. 54:1998;51-66.
18. Honma K.I., Honma S., Hiroshige T. Critical role of food amount for prefeeding corticosterone peak in rats. Am. J. Physiol. 245:1983;R339-44.
19. Hu Y., Bloomquist B.T., Cornfield L.J., DeCarr L.B., Flores-Riveros J.R., Friedman L., Jiang P., Lewis-Higgins L., Sadlowski Y., Schaefer J., Velazquez N., McCaleb M.L. Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior. J. Biol. Chem. 271:1996;26315-26319.
20. Jones M.A., VanNess J.M., Casto R.M., Overton J.M. Influence of food deprivation on sympathetic support of blood pressure in the spontaneously hypertensive rat. Nutrition Res. 15:1998;1581-1594.
21. Klemfuss H., Southerland S., Britton K.T. Cardiovascular actions of neuropeptide Y and social stress. Peptides. 19:1998;85-92.
22. Marsh D.J., Hollopeter G., Kafer K.E., Palmiter R.D. Role of the Y5 neuropeptide Y receptor in feeding and obesity. Nat. Med. 4:1998;718-721.
23. Matos F.F., Guss V., Korpinen C. Effects of neuropeptide Y (NPY) and [D-Trp32]NPY on monoamine and metabolite levels in dialysates from rat hypothalamus during feeding behavior. Neuropeptides. 30:1996;391-398.
24. Myers R.D., Wooten M.H., Ames C.D., Nyce J.W. Anorexic action of a new potential neuropeptide Y antagonist [D-Tyr27, 36, D-Thr32]-NPY (27-36) infused into the hypothalamus of the rat. Brain Res. Bull. 37:1995;237-245.
25. Overton J.M., VanNess J.M., Casto R.M. Food restriction reduces sympathetic support of blood pressure in spontaneously hypertensive rats. J. Nutr. 127:1997;655-660.
26. Palmiter R.D., Erickson J.C., Hollopeter G., Baraban S.C., Schwartz M.W. Life without neuropeptide Y. Recent Prog. Horm Res. 53:1998;163-199.
27. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, Sydney, 1986.
28. Pedrazzini T., Seydoux J., Kunstner P., Aubert J.F., Grouzmann E., Beermann F., Brunner H.R. Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor. Nat. Med. 4:1998;722-726.
29. Roscoe A.K., Leach S.M., Nyce J.W., Wooles W.R. Hypotensive effects of [D-Tyr27, 36, D-Thr32]-NPY-(27-36). Peptides. 8:1995;1411-1415.
30. Sahu A., Kalra P.S., Kalra S.P. Food deprivation and ingestion induce reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus. Peptides. 9:1988;83-86.
31. Sato K., Crofton J.T., Wang Y.X., Share L. Effects of gender on the central actions of neuropeptide Y and norepinephrine on vasopressin and blood pressure in the rat. Brain Res. 689:1995;71-78.
32. Schwartz M.W., Dallman M.F., Woods S.C. Hypothalamic response to starvation: implications for the study of wasting disorders. Am. J. Physiol. 269:1995;R949-R957.
33. Scott N.A., Webb V., Boublik J.H., Rivier J., Brown M.R. The cardiovascular actions of centrally administered NPY. Regul. Pept. 25:1989;247-258.
34. Shek E., Brands M., Hall J. Chronic leptin infusion increases arterial pressure. Hypertension. 31(part 2):1998;409-414.
35. Siri F.M. Sympathetic changes during development of cardiac hypertrophy in aortic-constricted rats. Am. J. Physiol. 255:1988;H452-H457.
36. Swoap S.J., Boddell P., Baldwin K.M. Interaction of hypertension and caloric restriction on cardiac mass and isomyosin expression. Am. J. Physiol. 268:1995;R33-R39.
37. Van Dijk G., Bottone A.E., Strubbe J.H., Steffens A.B. Hormonal and metabolic effects of paraventricular hypothalamic administration of neuropeptide Y during rest and feeding. Brain Res. 660:1994;96-103.
38. VanNess J.M., Casto R.M., DeMaria J.E., Overton J.M. Food restriction attenuates the blood pressure response to paraventricular hypothalamic nuclei lesions in aortic coarctation hypertension. Brain Res. 792:1998;237-245.
39. VanNess J.M., Casto R.M., Overton J.M. Antihypertensive effects of food-intake restriction in aortic coarctation hypertension. J. Hypertens. 15:1997;1253-1262.
40. Young J.B., Landsberg L. Suppression of sympathetic nervous system by fasting. Science. 196:1977;1473-1475.
41. Young J.B., Mullin D., Landsberg L. Caloric restriction lowers blood pressure in the spontaneously hypertensive rat. Metabolism. 27:1978;1711-1714.