-
1
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley S. R., Schooley K., Smolak P. J., Din W. S., Huang C.-P., Nicholl J. K., Sutherland G. R., Smith T. D., Rauch C., Smith C. A., Goodwin R. G. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity. 3:1995;673-682.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.-P.5
Nicholl, J.K.6
Sutherland, G.R.7
Smith, T.D.8
Rauch, C.9
Smith, C.A.10
Goodwin, R.G.11
-
2
-
-
0031782909
-
TRAIL: A molecule with multiple receptors and control mechanisms
-
Griffith T. S., Lynch D. H. TRAIL: A molecule with multiple receptors and control mechanisms. Curr. Opinion Immunol. 10:1998;559-563.
-
(1998)
Curr. Opinion Immunol.
, vol.10
, pp. 559-563
-
-
Griffith, T.S.1
Lynch, D.H.2
-
3
-
-
17544367410
-
Induction of apoptosis by APO-2 ligand, a new member of the TNF cytokine family
-
Pitti R. M., Marsters S. A., Rupper S., Donahue C. J., Moore A., Ashkenazi A. Induction of apoptosis by APO-2 ligand, a new member of the TNF cytokine family. J. Biol. Chem. 271:1996;12687-12690.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12687-12690
-
-
Pitti, R.M.1
Marsters, S.A.2
Rupper, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
4
-
-
0030996297
-
The receptor for the cytotoxic ligand TRAIL
-
Pan G., O'Rourke K., Chinnaiyan A. M., Gentz R., Schoenfeld H.-J., Broger C., Loetscher H., Lesslauer W. The receptor for the cytotoxic ligand TRAIL. Science. 276:1997;111-113.
-
(1997)
Science
, vol.276
, pp. 111-113
-
-
Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
Gentz, R.4
Schoenfeld, H.-J.5
Broger, C.6
Loetscher, H.7
Lesslauer, W.8
-
5
-
-
0030762815
-
An antagonistic decoy receptor and a death domain-containing receptor for TRAIL
-
Pan G., Ni J., Wei Y.-f., Yu G. I., Gentz R., Dixit V. M. An antagonistic decoy receptor and a death domain-containing receptor for TRAIL. Science. 277:1997;815-818.
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.-f.3
Yu, G.I.4
Gentz, R.5
Dixit, V.M.6
-
6
-
-
0031414749
-
The novel receptor TRAIL-R4 induces NF-κB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
-
Degli-Esposti M. A., Dougall W. C., Smolak P. J., Waugh J. Y., Smith C. A., Goodwin R. G. The novel receptor TRAIL-R4 induces NF-κB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity. 7:1997;813-820.
-
(1997)
Immunity
, vol.7
, pp. 813-820
-
-
Degli-Esposti, M.A.1
Dougall, W.C.2
Smolak, P.J.3
Waugh, J.Y.4
Smith, C.A.5
Goodwin, R.G.6
-
7
-
-
0031405585
-
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-κB
-
Schneider P., Thome M., Burns K., Bodmer J.-L., Hofmann K., Kataoka T., Holler N., Tschopp J. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-κB. Immunity. 7:1997;831-836.
-
(1997)
Immunity
, vol.7
, pp. 831-836
-
-
Schneider, P.1
Thome, M.2
Burns, K.3
Bodmer, J.-L.4
Hofmann, K.5
Kataoka, T.6
Holler, N.7
Tschopp, J.8
-
8
-
-
0032530612
-
Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
-
Griffith T. S., Chin W. A., Jackson G. C., Lynch D. H., Kubin M. Z. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J. Immunol. 161:1998;2833-2840.
-
(1998)
J. Immunol.
, vol.161
, pp. 2833-2840
-
-
Griffith, T.S.1
Chin, W.A.2
Jackson, G.C.3
Lynch, D.H.4
Kubin, M.Z.5
-
9
-
-
0031905817
-
Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage
-
Mariani S. M., Krammer P. H. Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage. Eur. J. Immunol. 28:1998;973-982.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 973-982
-
-
Mariani, S.M.1
Krammer, P.H.2
-
10
-
-
0031945015
-
Surface expression of TRAIL/Apo-2 ligand in activated mouse T and B cells
-
Mariani S. M., Krammer P. H. Surface expression of TRAIL/Apo-2 ligand in activated mouse T and B cells. Eur. J. Immunol. 28:1998;1492-1498.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 1492-1498
-
-
Mariani, S.M.1
Krammer, P.H.2
-
12
-
-
0032447111
-
Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells
-
Zamai L., Ahmad M., Bennet I. M., Azzoni L., Alnemri E. S., Perussia B. Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells. J. Exp. Med. 188:1998;2375-2380.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2375-2380
-
-
Zamai, L.1
Ahmad, M.2
Bennet, I.M.3
Azzoni, L.4
Alnemri, E.S.5
Perussia, B.6
-
13
-
-
0032169208
-
TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells
-
Thomas W. D., Hersey P. TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells. J. Immunol. 161:1998;2195-2200.
-
(1998)
J. Immunol.
, vol.161
, pp. 2195-2200
-
-
Thomas, W.D.1
Hersey, P.2
-
14
-
-
0015821893
-
A rapid method for the isolation of functional thymus-derived murine lymphocytes
-
Julius M. H., Simpson E., Herzenberg L. A. A rapid method for the isolation of functional thymus-derived murine lymphocytes. Eur. J. Immunol. 3:1973;645-649.
-
(1973)
Eur. J. Immunol.
, vol.3
, pp. 645-649
-
-
Julius, M.H.1
Simpson, E.2
Herzenberg, L.A.3
-
15
-
-
0001637710
-
Identification of a monoclonal antibody specific to a murine T3 polypeptide
-
Leo O., Foo M., Sachs D. H., Samelson L. E., Bluestone J. A. Identification of a monoclonal antibody specific to a murine T3 polypeptide. Proc. Natl. Acad. Sci. USA. 84:1987;1374-1378.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 1374-1378
-
-
Leo, O.1
Foo, M.2
Sachs, D.H.3
Samelson, L.E.4
Bluestone, J.A.5
-
16
-
-
0025261191
-
Measurement by quantitative PCR of changes in HPRT, PGK-1, PGK-2, APRT, Mtase and Zyf gene transcripts during mouse spermatogenesis
-
Singer-Sam J., Robinson M. O., Bellvè, Simon M. I., Riggs A. P. Measurement by quantitative PCR of changes in HPRT, PGK-1, PGK-2, APRT, Mtase and Zyf gene transcripts during mouse spermatogenesis. Nucleic Acids Res. 18:1990;1255-1259.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 1255-1259
-
-
Singer-Sam, J.1
Robinson, M.O.2
Bellvè3
Simon, M.I.4
Riggs, A.P.5
-
17
-
-
0028014460
-
Signal transduction by lymphocyte antigen receptors
-
Weiss A., Littman D. R. Signal transduction by lymphocyte antigen receptors. Cell. 76:1994;263-274.
-
(1994)
Cell
, vol.76
, pp. 263-274
-
-
Weiss, A.1
Littman, D.R.2
-
18
-
-
0023664272
-
Genistein, a specific inhibitor of tyrosine-specific protein kinases
-
Akiyama T., Ishada J., Nakagawa S., Ogawara H., Watanabe S. I., Itoh N., Shibuya M., Fukami Y. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J. Biol. Chem. 262:1987;5592-5595.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 5592-5595
-
-
Akiyama, T.1
Ishada, J.2
Nakagawa, S.3
Ogawara, H.4
Watanabe, S.I.5
Itoh, N.6
Shibuya, M.7
Fukami, Y.8
-
19
-
-
0025094356
-
Inhibition of tyrosine phosporylation prevents T-cell receptor-mediated signal transduction
-
June C. H., Fletcher M. C., Ledbetter J. A., Schieven G. L., Siegel J. N., Phillips A. F., Samelson L. E. Inhibition of tyrosine phosporylation prevents T-cell receptor-mediated signal transduction. Proc. Natl. Acad. Sci. USA. 87:1990;7722-7726.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 7722-7726
-
-
June, C.H.1
Fletcher, M.C.2
Ledbetter, J.A.3
Schieven, G.L.4
Siegel, J.N.5
Phillips, A.F.6
Samelson, L.E.7
-
20
-
-
0031008982
-
Inhibition of protein tyrosine kinases or protein kinase C prevents nonspecific killer T lymphocyte-mediated tumoricidal activity
-
Stewart B. H., Hoskin D. W. Inhibition of protein tyrosine kinases or protein kinase C prevents nonspecific killer T lymphocyte-mediated tumoricidal activity. Biochim. Biophys. Acta. 1356:1997;333-342.
-
(1997)
Biochim. Biophys. Acta
, vol.1356
, pp. 333-342
-
-
Stewart, B.H.1
Hoskin, D.W.2
-
21
-
-
0029015694
-
A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids
-
Nakanishi S., Catt K. J., Balla T. A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids. Proc. Natl. Acad. Sci. USA. 92:1995;5317-5321.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5317-5321
-
-
Nakanishi, S.1
Catt, K.J.2
Balla, T.3
-
22
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
Vlahos C. J., Matter W. F., Hui K. Y., Brown R. F. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 269:1994;5241-5248.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
23
-
-
0029965232
-
PI 3-kinase: A pivotal pathway in T-cell activation
-
Ward S. G., June C. H., Olive D. PI 3-kinase: A pivotal pathway in T-cell activation. Immunol. Today. 17:1996;187-197.
-
(1996)
Immunol. Today
, vol.17
, pp. 187-197
-
-
Ward, S.G.1
June, C.H.2
Olive, D.3
-
24
-
-
0024550448
-
Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C
-
Kobayashi E., Nakano H., Morimoto M., Tamaoki T. Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159:1989;548-553.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.159
, pp. 548-553
-
-
Kobayashi, E.1
Nakano, H.2
Morimoto, M.3
Tamaoki, T.4
-
25
-
-
0022491419
-
Staurosporine, a potent inhibitor of phospholipid/Ca2+ dependent protein kinase
-
Tamaoki T., Nomoto H., Takahashi I., Kato Y., Norimoto M., Tomita F. Staurosporine, a potent inhibitor of phospholipid/Ca2+ dependent protein kinase. Biochem. Biophys. Res. Commun. 135:1986;397-402.
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.135
, pp. 397-402
-
-
Tamaoki, T.1
Nomoto, H.2
Takahashi, I.3
Kato, Y.4
Norimoto, M.5
Tomita, F.6
-
26
-
-
0026643141
-
Identification of calcineurin as a key signaling enzyme in T-lymphocyte activation
-
Clipstone N. A., Crabtree G. R. Identification of calcineurin as a key signaling enzyme in T-lymphocyte activation. Nature. 357:1992;695-697.
-
(1992)
Nature
, vol.357
, pp. 695-697
-
-
Clipstone, N.A.1
Crabtree, G.R.2
-
27
-
-
0028048353
-
T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A
-
Anel A., Buferne M., Boyer C., Schmitt-Verhulst A.-M., Golstein P. T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A. Eur. J. Immunol. 24:1994;2469-2476.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 2469-2476
-
-
Anel, A.1
Buferne, M.2
Boyer, C.3
Schmitt-Verhulst, A.-M.4
Golstein, P.5
-
28
-
-
0027378246
-
Cytotoxic cell proteinase gene expression and cytolytic activity by anti-CD3-activated cytotoxic T lymphocytes is sensitive to cyclosporin a but is not dependent on interleukin-2 synthesis
-
Kaiser M., Brooks-Kaiser J., Fitzpatrick L., Bleackley R. C., Hoskin D. W. Cytotoxic cell proteinase gene expression and cytolytic activity by anti-CD3-activated cytotoxic T lymphocytes is sensitive to cyclosporin a but is not dependent on interleukin-2 synthesis. J. Leukoc. Biol. 54:1993;458-464.
-
(1993)
J. Leukoc. Biol.
, vol.54
, pp. 458-464
-
-
Kaiser, M.1
Brooks-Kaiser, J.2
Fitzpatrick, L.3
Bleackley, R.C.4
Hoskin, D.W.5
-
29
-
-
0026721092
-
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase
-
Kuo C. J., Chung J., Florentino D. F., Flanagan W. M., Blenis J., Crabtree G. R. Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature. 358:1992;70-73.
-
(1992)
Nature
, vol.358
, pp. 70-73
-
-
Kuo, C.J.1
Chung, J.2
Florentino, D.F.3
Flanagan, W.M.4
Blenis, J.5
Crabtree, G.R.6
-
30
-
-
0025977970
-
The effect of the immunosuppressant FK506 on alternate pathways of T cell activation
-
Bierer B. E., Schreiber S. L., Burakoff S. J. The effect of the immunosuppressant FK506 on alternate pathways of T cell activation. Eur. J. Immunol. 21:1991;439-445.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 439-445
-
-
Bierer, B.E.1
Schreiber, S.L.2
Burakoff, S.J.3
-
31
-
-
0025190516
-
Induction of perforin and serine esterases in a murine cytotoxic T lymphocyte clone
-
Liu C. C., Joag S. V., Kwon B. S., Young J. D.-E. Induction of perforin and serine esterases in a murine cytotoxic T lymphocyte clone. J. Immunol. 144:1990;1196-1201.
-
(1990)
J. Immunol.
, vol.144
, pp. 1196-1201
-
-
Liu, C.C.1
Joag, S.V.2
Kwon, B.S.3
Young, J.D.-E.4
-
32
-
-
14844345988
-
Expression of the Fas ligand in cells of T cell lineage
-
Suda T., Okazaki T., Naito Y., Yokota T., Arai N., Ozaki S., Nakao K., Nagata S. Expression of the Fas ligand in cells of T cell lineage. J. Immunol. 154:1995;3806-3813.
-
(1995)
J. Immunol.
, vol.154
, pp. 3806-3813
-
-
Suda, T.1
Okazaki, T.2
Naito, Y.3
Yokota, T.4
Arai, N.5
Ozaki, S.6
Nakao, K.7
Nagata, S.8
-
33
-
-
0030050453
-
Cytotoxic T cells deficient in both functional Fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal graft-versus-host disease
-
Braun M. Y., Lowin B., French L., Acha-Orbea H., Tschopp J. Cytotoxic T cells deficient in both functional Fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal graft-versus-host disease. J. Exp. Med. 183:1996;657-661.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 657-661
-
-
Braun, M.Y.1
Lowin, B.2
French, L.3
Acha-Orbea, H.4
Tschopp, J.5
-
34
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S. Apoptosis by death factor. Cell. 88:1997;355-365.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
35
-
-
0028932731
-
The CTL's kiss of death
-
Berke G. The CTL's kiss of death. Cell. 81:1995;9-12.
-
(1995)
Cell
, vol.81
, pp. 9-12
-
-
Berke, G.1
-
36
-
-
0028850452
-
Wortmannin and its structural analogue demethoxyviridan inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase
-
Cross M. J., Stewart A., Hodgkin M. N., Kerr D. J., Wakelam M. J. O. Wortmannin and its structural analogue demethoxyviridan inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase. J. Biol. Chem. 270:1995;25352-25355.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25352-25355
-
-
Cross, M.J.1
Stewart, A.2
Hodgkin, M.N.3
Kerr, D.J.4
Wakelam, M.J.O.5
-
37
-
-
0024394417
-
Staurosporin, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases
-
Ruegg U. T., Burgess G. M. Staurosporin, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases. Trends Phamacol. Sci. 10:1989;218-220.
-
(1989)
Trends Phamacol. Sci.
, vol.10
, pp. 218-220
-
-
Ruegg, U.T.1
Burgess, G.M.2
-
38
-
-
0025998841
-
Use and specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors
-
Tamaoki T. Use and specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors. Methods Enzymol. 201:1991;340-347.
-
(1991)
Methods Enzymol.
, vol.201
, pp. 340-347
-
-
Tamaoki, T.1
-
39
-
-
0024833664
-
Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation
-
Emmel E. A., Verweij C. L., Durand D. B., Higgins K. M., Lacy E., Crabtree G. R. Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation. Science. 246:1989;1617-1620.
-
(1989)
Science
, vol.246
, pp. 1617-1620
-
-
Emmel, E.A.1
Verweij, C.L.2
Durand, D.B.3
Higgins, K.M.4
Lacy, E.5
Crabtree, G.R.6
-
40
-
-
0031573158
-
Inhibition of CTL induction by rapamycin. IL-2 rescues granzyme B and perforin expression but only partially restores cytotoxic activity
-
Makrigiannis A. P., Hoskin D. W. Inhibition of CTL induction by rapamycin. IL-2 rescues granzyme B and perforin expression but only partially restores cytotoxic activity. J. Immunol. 159:1997;4700-4707.
-
(1997)
J. Immunol.
, vol.159
, pp. 4700-4707
-
-
Makrigiannis, A.P.1
Hoskin, D.W.2
-
41
-
-
0031157453
-
Sequential development of structural and functional alterations in T cells from tumor-bearing mice
-
Correa M. R., Ochoa A. C., Ghosh P., Mizoguchi H., Harvey L., Longo D. L. Sequential development of structural and functional alterations in T cells from tumor-bearing mice. J. Immunol. 158:1997;5292-5296.
-
(1997)
J. Immunol.
, vol.158
, pp. 5292-5296
-
-
Correa, M.R.1
Ochoa, A.C.2
Ghosh, P.3
Mizoguchi, H.4
Harvey, L.5
Longo, D.L.6
|