PTEN gene transfer in human malignant glioma: Sensitization to irradiation and CD95L-induced apoptosis

Oncogene

Volumn 18, Issue 27, 1999, Pages 3936-3943

  Wick, Wolfgang ^a   Furnari, Frank B ^b   Naumann, Ulrike ^a   Cavenee, Webster K ^b   Weller, Michael ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CD95; Glioma; Irradiation; PKB PI 3 kinase; PTEN

Indexed keywords

CASPASE 3; FAS ANTIGEN; FAS LIGAND; PHOSPHATASE; PROTEIN KINASE B; SOMATOMEDIN C; WORTMANNIN;

APOPTOSIS; ARTICLE; DEPHOSPHORYLATION; ENZYME PHOSPHORYLATION; GENE TRANSFER; GLIOMA CELL; HUMAN; HUMAN CELL; IRRADIATION; PRIORITY JOURNAL; SENSITIZATION; TUMOR SUPPRESSOR GENE;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; FAS LIGAND PROTEIN; GAMMA RAYS; GENE TRANSFER TECHNIQUES; GLIOMA; GROWTH INHIBITORS; HUMANS; MEMBRANE GLYCOPROTEINS; MUTATION; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0033536225     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202774     Document Type: Article

References (24)

1. Baserga R. (1995). Cancer Res., 55, 249-252.
2. Cheney I, Johnson D, Vaillancourt M-T, Avanzini J, Morimoto A, Demers G, Wills K, Shabram P, Bolen J, Tavtigian S and Bookstein R. (1998). Cancer Res., 58, 2331-2334.
3. Crowder R and Freeman R. (1998). J. Neurosci., 18, 2933-2943.
4. Downward J. (1998). Curr. Biol., 10, 262-267.
5. Dudek H, Datta S, Franke T, Birnbaum M, Yao R, Cooper G, Segal R, Kaplan D and Greenberg M. (1997). Science, 275, 661-665.
6. Duerr E-M, Rollbrocker B, Hayashi Y, Peters N, Meyer-Puttlitz B, Louis D, Schramm J, Wiestler O, Parsons R, Eng C and Deimling v A. (1998). Oncogene, 16, 2259-2264.
7. Furnari F, Lin H, Huang H-J and Cavenee W. (1997). Proc. Natl. Acad. Sci. USA, 94, 12479-12484.
8. Häusler P, Papoff G, Eramo A, Reif K, Cantrell D and Ruberti G. (1998). Eur. J. Immunol., 28, 57-69.
9. Li D-M and Sun H. (1997). Cancer Res., 57, 2124-2129.
10. Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang S, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner S, Giovanella B, Ittmann M, Tycko B, Hibshoosh H, Wigler M and Parsons R. (1997). Science, 275, 1943-1947.
11. Liu W, James C, Frederick L, Alderete B and Jenkins R. (1997). Cancer Res., 57, 5254-5257.
12. Maehama T and Dixon J. (1998). J. Biol. Chem., 273, 13375-13378.
13. Marte B and Downward J. (1997). Trends Biochem. Sci., 22, 355-358.
14. Myers MP, Stolarov JP, Eng C, Li J, Wang SI, Wigler MH, Parsons R and Tonks NK. (1997). Proc. Natl. Acad. Sci. USA, 94, 9052-9057.
15. Rhei E, Kang L, Bolomolniy F, Federici M, Borgen P and Boyd J. (1997). Cancer Res., 57, 3657-3759.
16. Rieger J, Naumann U, Glaser T, Ashkenazi A and Weller M. (1998). FEBS Letts, 427, 124-128.
17. Roth W, Fontana A, Trepel M, Dichgans J, Reed JC and Weller M. (1997). Cancer Immunol. Immunother., 44, 55-63.
18. Schulz JB, Bremen D, Reed JC, Lommatzsch J, Takayama S, Wüller U, Löschmann P-A, Klockgether T and Weller M. (1997). J. Neurochem., 69, 2075-2086.
19. Tamura M, Gu J, Matsumoto K, Aota S-i, Parsons R and Yamada K. (1998). Science, 280, 1614-1617.
20. Teng D-F, Hu R, Lin H, Davis T, Iliev D, Frye C, Swedlund B, Hansen K, Vinson V, Gumpper K, Ellis L, El-Nagger A, Frazier M, Jasser S, Langford L, Lee J, Mills G, Pershouse M, Pollack R, Tornos C, Troncoso P, Yung W, Fujii G, Berson A, Bookstein R, Bolen J, Tavtigian S and Steck P. (1997). Cancer Res., 57, 5221-5225.
21. Wang S, Puc J, Li J, Bruce J, Cairns P, Sidransky D and Parsons R. (1997). Cancer Res., 57, 4183-4186.
22. Weller M, Frei K, Groseurth P, Krammer PH and Yonekawa Y. (1994). J. Clin. Invest., 94, 954-964.
23. Weller M, Rieger J, Grimmel C, Van Meir E, De Tribolet N, Krajewski S, Reed J, Von Deimling A and Dichgans J. (1998). Int. J. Cancer, 79, 1-5.
24. Weller M, Trepel M, Grimmel C, Schabet M, Bremen D, Krajewski S and Reed JC. (1997). Neurol. Res., 19, 459-470.