Thiazole-derived potent, highly bioavailable short duration growth hormone secretagogues

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 13, 1999, Pages 1761-1766

  Yang, Lihu ^a   Morriello, Greg ^a   Leung, Kwan ^a   Jacks, Tom ^a   Cheng, Kang ^a   Schleim, Klaus D ^a   Smith, Roy ^a,b   Patchett, Arthur A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [(2 AMINO 2 METHYLPROPIONYLAMINO) 3 (1H INDOL 3 YL)PROPIONYL] 3 (4 THIAZOLYL)PIPERIDINECARBOXYLIC ACID ETHYL ESTER; GROWTH HORMONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG POTENCY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; BIOLOGICAL AVAILABILITY; DOGS; GROWTH HORMONE; MODELS, CHEMICAL; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TIME FACTORS;

EID: 0033526912     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00286-3     Document Type: Article

References (13)

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