Presence of up-stream and downstream components of a mitogen-activated protein kinase pathway in the PSD of the rat forebrain

Brain Research

Volumn 840, Issue 1-2, 1999, Pages 36-44

  Suzuki, Tatsuo ^a   Mitake, Shigehisa ^b   Murata, Shigeru ^a  

^a Res Ctr Aging Adaptation   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

Grb2; MAP kinase; Phospholipase A2; Post synaptic density; RSK; Shc; Sos

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE A2;

ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; ENZYME ACTIVATION; FOREBRAIN; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPSE;

ANIMALS; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PROSENCEPHALON; RATS; RATS, WISTAR; RIBOSOMAL PROTEIN S6 KINASES; SON OF SEVENLESS PROTEIN, DROSOPHILA; SUBCELLULAR FRACTIONS; SYNAPSES;

EID: 0033523440     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01762-X     Document Type: Article

References (73)

1. Abe K., Xie F.J., Saito H. Epidermal growth factor enhances short-term potentiation and facilitates induction of long-term potentiation in rat hippocampal slices. Brain Res. 547:1991;171-174.
2. 2+ concentration in rat hippocampal neurons. Brain Res. 587:1992;102-108.
3. Angenstein F., Greenough W.T., Weiler I.J. Metabotropic glutamate receptor-initiated translocation of protein kinase p90rsk to polyribosomes: a possible factor regulating synaptic protein synthesis. Proc. Natl. Acad. Sci. U.S.A. 95:1998;15078-15083.
4. Blenis J. Signal transduction via the MAP kinases: proceed at your own RSK. Proc. Natl. Acad. Sci. U.S.A. 90:1993;5889-5892.
5. Bohm M., Moellmann G., Cheng E., Alvarez-Franco M., Wagner S., Sassone-Corsi P., Halaban R. Identification of p90RSK as the probable CREB-Ser133 kinase in human melanocytes. Cell Growth Differ. 6:1995;291-302.
6. Brambilla R., Gnesutta N., Minichiello L., White G., Roylance A.J., Herron C.E., Ramsey M., Wolfer D.P., Cestari V., Rossi-Arnaud C., Grant S.G., Chapman P.F., Lipp H.P., Sturani E., Klein R. A role for the Ras signalling pathway in synaptic transmission and long-term memory. Nature. 390:1997;281-286.
7. Böraud C., Henzel W.J., Baeuerle P.A. Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-κB activation. Proc. Natl. Acad. Sci. U.S.A. 96:1999;429-434.
8. Chen H.-J., Rojas-Soto M., Oguni A., Kennedy M.B. A synaptic Ras-GTPase Activating Protein (p135 SynGAP) inhibited by CaM kinase II. Neuron. 20:1998;895-904.
9. Chen R.H., Sarnecki C., Blenis J. Nuclear localization and regulation of erk- and rsk-encoded protein kinases. Mol. Cell. Biol. 12:1992;915-927.
10. Chen R.H., Tung R., Abate C., Blenis J. Cytoplasmic to nuclear signal transduction by mitogen-activated protein kinase and 90 kDa ribosomal S6 kinase. Biochem. Soc. Trans. 21:1993;895-900.
11. Cherniack A.D., Klarlund J.K., Czech M.P. Phosphorylation of the Ras nucleotide exchange factor son of sevenless by mitogen-activated protein kinase. J. Biol. Chem. 269:1994;4717-4720.
12. Chuang C.F., Ng S.Y. Functional divergence of the MAP kinase pathway, ERK1 and ERK2 activate specific transcription factors. FEBS Lett. 346:1994;229-234.
13. Cleghon V., Morrison D.K. Raf-1 interacts with Fyn and Src in a non-phosphotyrosine-dependent manner. J. Biol. Chem. 269:1994;17749-17755.
14. Daum G., Eisenmann-Tappe I., Fries H.W., Troppmair J., Rapp U.R. The ins and outs of Raf kinase. Trends Biochem. Sci. 19:1994;474-480.
15. Davis R.J. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268:1993;14553-14556.
16. Diaz-Meco M.T., Lozano J., Municio M.M., Berra E., Frutos S., Sanz L., Moscat J. Evidence for the in vitro and in vivo interaction of Ras with protein kinase Cζ J. Biol. Chem. 269:1994;31706-31710.
17. Downes C.P., Carter A.N. Phosphoinositide 3-kinase: a new effector in signal transduction? Cell. Signalling. 3:1991;501-513.
18. Egan S.E., Giddings B.W., Brooks M.W., Buday L., Sizeland A.M., Weinberg R.A. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature. 363:1993;45-51.
19. English J.D., Sweatt J.D. Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation. J. Biol. Chem. 271:1996;24329-24332.
20. Faundez V., Krauss R., Holuigue L., Garrido J., Gonzalez A. Epidermal growth factor receptor in synaptic fractions of the rat central nervous system. J. Biol. Chem. 267:1992;20363-20370.
21. Fiore R.S., Bayer V.E., Pelech S.L., Posada J., Cooper J.A., Baraban J.M. p42 Mitogen-activated protein kinase in brain: prominent localization in neuronal cell bodies and dendrites. Neuroscience. 55:1993;463-472.
22. Fukuda M., Gotoh I., Gotoh Y., Nishida E. Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal. J. Biol. Chem. 271:1996;20024-20028.
23. Fukuda M., Gotoh Y., Nishida E. Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J. 16:1997;1901-1908.
24. Ginty D.D., Bonni A., Greenberg M.E. Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell. 77:1994;713-725.
25. Gomez-Pinilla F., Knauer D.J., Nieto-Sampedro M. Epidermal growth factor receptor immunoreactivity in rat brain. Development and cellular localization. Brain Res. 438:1998;385-390.
26. Kim S., Kikuchi A., Mizoguchi A., Takai Y. Intrasynaptosomal distribution of the ras, rho, and smg-25A GTP-binding proteins in bovine brain. Mol. Brain Res. 6:1989;167-176.
27. Kim J.H., Liao D., Lau L.-F., Huganir R.L. SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family. Neuron. 20:1998;683-691.
28. Kornhauser J.M., Greenberg M.E. A kinase to remember: dual roles for MAP kinase in long-term memory. Neuron. 18:1997;839-842.
29. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
30. Lakshmanan J., Weichsel M.E. Jr., Fisher D.A. Epidermal growth factor in synaptosomal fractions of mouse cerebral cortex. J. Neurochem. 46:1986;1081-1085.
31. Lederfein D., Huang Y.-Y., Rubin J.S., Yukawa K., Kandel E.R. Tissue plasminogen activator alters gene expression in the hippocampal neurons: a possible role for hepatocyte growth factor. Soc. Neurosci. Abstr. 23:1997;664.
32. Li S., Sedivy J.M. Raf-1 protein kinase activates the NF-κB transcription factor by dissociating the cytoplasmic NF-κB-IκB complex. Proc. Natl. Acad. Sci. U.S.A. 90:1993;9247-9251.
33. Li S., Janosch P., Tanji M., Rosenfeld G.C., Waymire J.C., Mischak H., Kolch W., Sedivy J.M. Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins. EMBO J. 14:1995;685-696.
34. Lin L.L., Wartmann M., Lin A.Y., Knopf J.L., Seth A., Davis R.J. cPLA2 is phosphorylated and activated by MAP kinase. Cell. 72:1993;269-278.
35. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
36. Martin H., Rostas J., Patel Y., Aitken A. Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies. J. Neurochem. 63:1994;2259-2265.
37. Migliaccio E., Mele S., Salcini A.E., Pelicci G., Lai K.M., Superti-Furga G., Pawson T., Di Fiore P.P., Lanfrancone L., Pelicci P.G. Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway. EMBO J. 16:1997;706-716.
38. Mihály A., Oláh Z., Krug M., Kuhnt U., Matthies H., Rapp U.R., Joó F. Transient increase of raf protein kinase-like immunoreactivity in the rat dentate gyrus during long-term potentiation. Neurosci. Lett. 116:1990;45-50.
39. Mihály A., Oravecz T., Oláh Z., Rapp U.R. Immunohistochemical localization of raf protein kinase in dendritic spines and spine apparatuses of the rat cerebral cortex. Brain Res. 547:1991;309-314.
40. Mihály A., Endrész V., Oravecz T., Rapp U.R., Kuhnt U. Immunohistochemical detection of raf protein kinase in cerebral cortical areas of adult guinea pigs and rats. Brain Res. 627:1993;225-238.
41. Mizoguchi A., Ueda T., Ikeda K., Shiki H., Mizoguchi H., Takai Y. Localization and subcellular distribution of cellular ras gene products in rat brain. Mol. Brain Res. 5:1989;31-44.
42. Muthalif M.M., Benter I.F., Karzoun N., Fatima S., Harper J., Uddin M.R., Malik K.U. 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. Proc. Natl. Acad. Sci. U.S.A. 95:1998;12701-12706.
43. Nakamura T., Sanokawa R., Sasaki Y., Ayusawa D., Oishi M., Mori N. N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway. Oncogene. 13:1996;1111-1121.
44. Nakamura T., Muraoka S., Sanokawa R., Mori N. N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling. J. Biol. Chem. 273:1998;6960-6967.
45. Nemenoff R.A., Winitz S., Qian N.X., Van Putten V., Johnson G.L., Heasley L.E. Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C. J. Biol. Chem. 268:1993;1960-1964.
46. Oláh Z., Komoly S., Nagashima N., Joó F., Rapp U.R., Anderson W.B. Cerebral ischemia induces transient intracellular redistribution and intranuclear translocation of the raf proto-oncogene product in hippocampal pyramidal cells. Exp. Brain Res. 84:1991;403-410.
47. Orban P.C., Chapman P.F., Brambilla R. Is the Ras-MAPK signalling pathway necessary for long-term memory formation? Trends Neurosci. 21:1999;38-44.
48. Rine J., Kim S.H. A role for isoprenoid lipids in the localization and function of an oncoprotein. New Biol. 2:1990;219-226.
49. Rodriguez-Viciana P., Warne P.H., Dhand R., Vanhaesebroeck B., Gout I., Fry M.J., Waterfield M.D., Downward J. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature. 370:1994;527-532.
50. Rosen L.B., Ginty D.D., Weber M.J., Greenberg M.E. Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron. 12:1994;1207-1221.
51. Rozakis-Adcock M., McGlade J., Mbamalu G., Pelicci G., Daly R., Li W., Batzer A., Thomas S., Brugge J., Pelicci P.G., Schlessinger J., Pawson T. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature. 360:1992;689-692.
52. Schouten G.J., Vertegaal A.C., Whiteside S.T., Israel A., Toebes M., Dorsman J.C., van der Eb A.J., Zantema A. IκBα is a target for the mitogen-activated 90 kDa ribosomal S6 kinase. EMBO J. 16:1997;3133-3144.
53. Sturani E., Abbondio A., Branduardi P., Ferrari C., Zippel R., Martegani E., Vanoni M., Denis-Donini S. The Ras guanine nucleotide exchange factor CDC25Mm is present at the synaptic junction. Exp. Cell Res. 235:1997;117-123.
54. Suzuki T. Protein kinases involved in the expression of long-term potentiation. Int. J. Biochem. 26:1994;735-744.
55. Suzuki T., Okumura-Noji K. NMDA receptor subunits ε1 (NR2A) and ε2 (NR2B) are substrates for Fyn in the postsynaptic density fraction isolated from the rat brain. Biochem. Biophys. Res. Commun. 216:1995;582-588.
56. Suzuki T., Okumura-Noji K., Nishida E. ERK2-type mitogen-activated protein kinase (MAPK) and its substrates in postsynaptic density fractions from the rat brain. Neurosci. Res. 22:1995;277-285.
57. Suzuki T. Messenger molecules that transmit synaptic informations to the nucleus. Neurosci. Res. 25:1996;1-6.
58. Suzuki T., Mitake S., Okumura-Noji K., Shimizu H., Tada T., Fujii T. Localization of α-internexin in the postsynaptic density of the rat brain. Brain Res. 765:1997;74-80.
59. Suzuki T., Mitake S., Okumura-Noji K., Yang J.-P., Fujii T., Okamoto T. Presence of NF-κB-like and IκB-like immunoreactivities in postsynaptic densities. NeuroReport. 8:1997;2931-2935.
60. Suzuki T., Usuda N., Ishiguro H., Mitake S., Nagatsu T., Okumura-Noji K. Occurrence of a transcription factor, cAMP response element-binding protein (CREB), in the postsynaptic sites of the brain. Mol. Brain Res. 61:1998;69-77.
61. Suzuki T., Tian Q.B., Nakayama K. Detection and sequencing of mRNAs associated with postsynpatic density fraction. Soc. Neurosci. Abstr. 24:1998;572.
62. Terlau H., Seifert W. Influence of epidermal growth factor on long-term potentiation in the hippocampal slice. Brain Res. 484:1989;352-356.
63. Tongiorgi E., Righi M., Cattaneo A. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. J. Neurosci. 17:1997;9492-9505.
64. Tucker M.S., Khan I., Fuchs-Young R., Price S., Steininger T.L., Greene G., Wainer B.H., Rosner M.R. Localization of immunoreactive epidermal growth factor receptor in neonatal and adult rat hippocampus. Brain Res. 631:1993;65-71.
65. Tzivion G., Luo Z., Avruch J. A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity. Nature. 394:1998;88-92.
66. Whitmarsh A.J., Davis R.J. Structural organization of MAP-kinase signaling molecules by scaffold proteins in yeast and mammals. Trends Biochem. Sci. 23:1998;481-485.
67. 3H ]glutamate to fresh or frozen synaptic membrane and postsynaptic density fractions isolated from cerebral cortex and cerebellum of fresh or frozen canine brain J. Neurochem. 46:1986;831-841.
68. Wu K., Xu J.L., Suen P.C., Levine E., Huang Y.Y., Mount H.T., Lin S.Y., Black I.B. Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density. Mol. Brain Res. 43:1996;286-290.
69. Xia Z., Dudek H., Miranti C.K., Greenberg M.E. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J. Neurosci. 16:1996;5425-5436.
70. Xing J., Ginty D.D., Greenberg M.E. Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science. 273:1996;959-963.
71. Yamamori B., Kuroda S., Shimizu K., Fukui K., Ohtsuka T., Takai Y. Purification of a Ras-dependent mitogen-activated protein kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins. J. Biol. Chem. 270:1995;11723-11726.
72. Yamauchi K., Holt K., Pessin J.E. Phosphatidylinositol 3-kinase functions upstream of Ras and Raf in mediating insulin stimulation of c-fos transcription. J. Biol. Chem. 268:1993;14597-14600.
73. Zhao Y., Bjorbaek C., Moller D.E. Regulation and interaction of pp90 (rsk) isoforms with mitogen-activated protein kinases. J. Biol. Chem. 271:1996;29773-29779.