Shape-selective recognition and self-assembly of mm-scale components [4]

Journal of the American Chemical Society

Volumn 121, Issue 8, 1999, Pages 1754-1755

  Choi, Insung S ^a   Bowden, Ned ^a   Whitesides, George M ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITY; CHIRALITY; ENANTIOMER; HYDROGEN BOND; HYDROPHOBICITY; LETTER; LIGAND BINDING; PROTEIN ASSEMBLY;

EID: 0033518867     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9816032     Document Type: Letter

References (14)

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12. -1.
13. We addressed the statistics of these assembly processes in this system by repeating representative assemblies 20 times. The assemblies were allowed to aggregate in 20 trials, each for 1 h; at the end of the hour, we counted the receptors and ligands that had bound correctly as a success, and all other assemblies as failures. Each experiment contained two receptors for a total of 40 possible receptor-ligand pairs.
14. Ligands themselves formed unstable heterodimers depicted in Figure 1b and c. We also observed the formation of homodimers of 4a and 4b, 4a· 4a and 4b·4b. After they formed, the homodimers were stable and did not dissociate under the conditions used.