Differential modulation of proliferation, matrix metalloproteinase expression and invasion of human head and neck squamous carcinoma cells by c- erbB ligands

Clinical and Experimental Metastasis

Volumn 17, Issue 7, 1999, Pages 631-639

  O Charoenrat, Pornchai ^a,b   Rhys Evans, Peter ^a   Court, William J ^b   Box, Gary M ^b   Eccles, Suzanne A ^b  

^a ROYAL MARSDEN HOSPITAL   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Betacellulin; c erbB receptors; Epidermal growth factor; Head and neck cancer; Heregulin; Matrix metalloproteinase; Tumour invasion

Indexed keywords

BETACELLULIN; COLLAGENASE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; GELATINASE A; GELATINASE B; LIGAND; MATRILYSIN; MATRIX METALLOPROTEINASE; MESSENGER RNA; NEU DIFFERENTIATION FACTOR; PROTEIN C ERB B; PROTEIN TYROSINE KINASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER INVASION; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; MITOGENICITY; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA;

ANTIBODIES, MONOCLONAL; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CULTURE MEDIA, CONDITIONED; ENZYME INDUCTION; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GROWTH SUBSTANCES; HEAD AND NECK NEOPLASMS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; METALLOENDOPEPTIDASES; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEUREGULIN-1; PHARYNGEAL NEOPLASMS; PHENOTYPE; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TUMOR CELLS, CULTURED;

EID: 0033505391     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006751016860     Document Type: Article

References (38)

1. 1. Eccles SA, Modjtahedi H, Box G et al. Significance of the c-erbB family of receptor tyrosine kinases in metastatic cancer and their potential as targets for immunotherapy. Inv Metastasis 1994; 14: 337-48.
2. 2. Klapper LN, Kirschbaum MH, Sela M et al. Biochemical and clinical implications of the ErbB/HER signalling network of growth factor receptors. Adv Cancer Res 2000; 77: 25-79.
3. 3. Riese II DJ, Stern DE. Specificity within the EGF family/ErbB receptor family signaling network. BioEssays 1998; 20: 41-8.
4. 4. Wen D, Suggs SV, Karunagaran D et al. Structural and functional aspects of the multiplicity of Neu differentiation factors. Mol Cell Biol 1994; 14: 1909-19.
5. 5. Weiss FU, Wallasch C, Campiglio M et al. Distinct characteristics of heregulin signals mediated by HER3 or HER4. J Cell Physiol 1997; 173: 187-95.
6. 6. Klapper LN, Glathe S, Vaisman N et al. The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors. PNAS 1999; 96: 4995-5000.
7. 7. Spencer KSR, Graus-Porta D, Leng J et al. ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases. J Cell Biol 2000; 148: 385-97.
8. 8. Dassomille O, Formento JL, Francoual M et al. Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer. J Clin Oncol 1993; 11: 1873-8.
9. 9. Grandis JR, Melhem MF, Gooding WE et al. Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998; 90: 824-32.
10. 10. Kearsley JH, Leonard JH, Walsh MD et al. A comparison of epidermal growth factor receptor (EGFR) and c-erbB-2 oncogene expression in head and neck squamous cell carcinomas. Pathology 1991; 23: 189-94.
11. 11. Riviere A, Becker J, Loning T. Comparative investigation of c-erbB2/neu expression in head and neck tumors and mammary cancer. Cancer 1991; 67: 2142-9.
12. 12. Craven JM, Pavelic ZP, Stambrook PJ et al. Expression of c-erbB2 gene in human head and neck carcinoma. Anticancer Res 1992; 12: 2273-6.
13. 13. Field JK, Spandidos DA, Yiagnisis M et al. c-erbB2 expression in squamous cell carcinoma of the head and neck. Anticancer Res 1992; 12: 613-20.
14. 14. Hou L, Shi D, Tu SM et al. Oral cancer progression and c-erbB-2/neu proto-oncogene expression. Cancer Lett 1992; 65: 215-20.
15. 15. Issing WJ, Heppt WJ, Kastenbauer ER. erbB-3, a third member of the erbB/epidermal growth factor receptor gene family: Its expression in head and neck cancer cell lines. Eur Arch Otorhinolaryngol 1993; 250: 392-5.
16. 16. Shintani S, Funayama T, Yoshihama Y et al. Prognostic significance of ERBB3 overexpression in oral squamous cell carcinoma. Cancer Lett 1995; 95: 79-83.
17. 17. Rodrigo JP, Ramos S, Lazo PS et al. Amplification of ERBB oncogenes in squamous cell carcinomas of the head and neck. Eur J Cancer Part A 1996; 32: 2004-10.
18. 18. Ibrahim SO, Vasstrand EN, Liavaag PG et al. Expression of c-erbB proto-oncogene family members in squamous cell carcinoma of the head and neck. Anticancer Res 1997; 17: 4539-46.
19. 19. Funayama T, Nakanishi T, Takahashi K et al. Overexpression of c-erbB-3 in various stages of human squamous cell carcinomas. Oncology 1998; 55: 161-7.
20. 20. Srinivasan R, Poulsom R, Hurst HC et al. Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types. J Pathol 1998; 185: 236-45.
21. 21. Stetler-Stevenson WG, Aznavoorian S, Liotta A. Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu Rev Cell Biol 1993; 9: 541-73.
22. 22. Jones JL, Walker RA. Control of matrix metalloproteinase activity in cancer. J Pathol 1997; 183: 377-9.
23. 23. O-charoenrat P, Modjtahedi H, Rhys-Evans P et al. Epidermal growth factor-like ligands differentially upregulate matrix metalloproteinase-9 in head and neck squamous carcinoma cells. Cancer Res 2000; 60: 1121-8.
24. 24. O-charoenrat P, Rhys-Evans P, Modjtahedi H et al. Over-expression of epidermal growth factor receptor in human head and neck squamous carcinoma cell lines correlates with matrix metalloproteinase-9 expression and in vitro invasion. Int J Cancer 2000: in press.
25. 25. Modjtahedi H, Komurasaki T, Toyoda H et al. Anti-EGFR monoclonal antibodies which act as EGF, TGFa, HB-EGF and BTC antagonists block the binding of epiregulin to EGFR-expressing tumours. Int J Cancer 1998; 75: 310-6.
26. 26. Styles JM, Harrison S, Gusterson BA et al. Rat monoclonal antibodies to the external domain of the product of the C-erbB-2 proto-oncogene. Int J Cancer 1990; 45: 320-4.
27. 27. Thomas GT, Lewis MP, Speight PM. Matrix metalloproteinases and oral cancer. Oral Oncol 1999; 35: 227-33.
28. 28. Carraway KLI, Sliwkowski MX, Akita R et al. The erbB3 gene product is a receptor for heregulin. J Biol Chem 1994; 269: 14303-6.
29. 29. Lewis GD, Lofgren JA, McMurrey AE et al. Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness. Cancer Res 1996; 56: 1457-65.
30. r 95,000 type IV collagenase/gelatinase and interstitial fibroblast-type collagenase by rat mucosal keratinocytes. J Biol Chem 1993; 268: 19143-51.
31. 31. Kerr LD, Holt JT, Matrisian LM. Growth factors regulate transin gene expression by c-fos-dependent and c-fos-independent pathways. Science 1988; 242: 1424-7.
32. 32. Rosenthal EL, Johnson TM, Allen ED et al. Role of the plasminogen activator and matrix metalloproteinase systems in epidermal growth factor- and scatter factor-stimulated invasion of carcinoma cells. Cancer Res 1998; 58: 5221-30.
33. 33. Gaire M, Magbanua Z, McDonnell S et al. Structure and expression of the human gene for the matrix metalloproteinase matrilysin. J Biol Chem 1994; 269: 2032-40.
34. 34. Windsor LJ, Grenett H, Birkedal-Hansen B et al. Cell-type specific regulation of SL-1 and SL-2 genes. Induction of the SL-2 gene but not the SL-1 gene by human keratinocytes in response to cytokines and phorbol esters. J Biol Chem 1993; 268: 17341-7.
35. 35. Basset P, Bellocq JP, Wolf C et al. A novel metalloproteinase gene family in humans consists of at least four members. Biochem J 1990; 348: 699-704.
36. 36. Borden P, Heller RA. Transcriptional control of matrix metalloproteinases and the tissue inhibitors of matrix metalloproteinases. Crit Rev Eukaryot Gene Expr 1997; 7: 159-78.
37. 37. Sato H, Seiki M. Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 1993; 8: 395-405.
38. 38. Ye D, Mendelsohn J, Fan Z. Augmentation of a humanized anti-HER2 mAb4D5 induced growth inhibition by a human-mouse chimeric anti-EGF receptor mAb C225. Oncogene 1999; 18: 731-8.