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Volumn 112, Issue 22, 1999, Pages 4007-4016

Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system

Author keywords

Microglial cell; Nonproteolytic; Tissue plasminogen activation

Indexed keywords

BIOLOGICAL MARKER; CYTOKINE; EXCITOTOXIN; LIPOPOLYSACCHARIDE; TISSUE PLASMINOGEN ACTIVATOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 0033491091     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (130)

References (59)
  • 1
    • 0031659763 scopus 로고    scopus 로고
    • Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55 TNF receptor signaling in the central nervous system of transgenic mice
    • Akassoglou, K., Bauer, J., Kassiotis, G., Pasparakis, M., Lassmann, H., Kollias, G. and Probert, L. (1998). Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55 TNF receptor signaling in the central nervous system of transgenic mice. Am. J. Pathol. 153, 801-813.
    • (1998) Am. J. Pathol. , vol.153 , pp. 801-813
    • Akassoglou, K.1    Bauer, J.2    Kassiotis, G.3    Pasparakis, M.4    Lassmann, H.5    Kollias, G.6    Probert, L.7
  • 2
    • 0025865829 scopus 로고
    • The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration
    • Andersson, P., Perry, V. and Gordon, S. (1991). The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration. Neuroscience 42, 201-214.
    • (1991) Neuroscience , vol.42 , pp. 201-214
    • Andersson, P.1    Perry, V.2    Gordon, S.3
  • 3
    • 0022518390 scopus 로고
    • Interaction of heparin with plasminogen activators and plasminogen: Effects on the activation of plasminogen
    • Andrade-Gordon, P. and Strickland, S. (1986). Interaction of heparin with plasminogen activators and plasminogen: effects on the activation of plasminogen. Biochemistry 25, 4033-4040.
    • (1986) Biochemistry , vol.25 , pp. 4033-4040
    • Andrade-Gordon, P.1    Strickland, S.2
  • 5
    • 0029899586 scopus 로고    scopus 로고
    • Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors
    • Bruce, A., Boling, W., Kindy, M., Peschon, J., Kraemer, P., Carpenter, M., Holtsberg, F. and Mattson, M. (1996). Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nature Med. 2, 788-794.
    • (1996) Nature Med. , vol.2 , pp. 788-794
    • Bruce, A.1    Boling, W.2    Kindy, M.3    Peschon, J.4    Kraemer, P.5    Carpenter, M.6    Holtsberg, F.7    Mattson, M.8
  • 7
    • 0028298886 scopus 로고
    • Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons
    • Bu, G., Maksymovich, E., Nerbonne, J. and Schwartz, A. (1994a). Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons. J. Biol. Chem. 269, 18521-18528.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18521-18528
    • Bu, G.1    Maksymovich, E.2    Nerbonne, J.3    Schwartz, A.4
  • 8
    • 0028359176 scopus 로고
    • Cellular receptors for the plasminogen activators
    • Bu, G., Warshawsky, I. and Schwartz, A. (1994b). Cellular receptors for the plasminogen activators. Blood 83, 3427-3436.
    • (1994) Blood , vol.83 , pp. 3427-3436
    • Bu, G.1    Warshawsky, I.2    Schwartz, A.3
  • 10
    • 0028043836 scopus 로고
    • The mouse tissue plasminogen activator gene 5′ flanking region directs appropriate expression in development and a seizure-enhanced response in the CNS
    • Carroll, P. M., Tsirka, S. E., Richards, W. G., Frohman, M. A. and Strickland, S. (1994). The mouse tissue plasminogen activator gene 5′ flanking region directs appropriate expression in development and a seizure-enhanced response in the CNS. Development 120, 3173-3183.
    • (1994) Development , vol.120 , pp. 3173-3183
    • Carroll, P.M.1    Tsirka, S.E.2    Richards, W.G.3    Frohman, M.A.4    Strickland, S.5
  • 11
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
    • Chao, C., Hu, S., Molitor, T., Shaskan, E. and Peterson, P. (1992). Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J. Immunol. 149, 2736-2741.
    • (1992) J. Immunol. , vol.149 , pp. 2736-2741
    • Chao, C.1    Hu, S.2    Molitor, T.3    Shaskan, E.4    Peterson, P.5
  • 12
    • 0028577356 scopus 로고
    • Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures
    • Chao, C. C. and Hu, S. (1994). Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures. Dev. Neurosci. 16, 172-179.
    • (1994) Dev. Neurosci. , vol.16 , pp. 172-179
    • Chao, C.C.1    Hu, S.2
  • 14
    • 0023642584 scopus 로고
    • Production of superoxide anions by a CNS macrophage, the microglia
    • Colton, C. A. and Gilbert, D. L. (1987). Production of superoxide anions by a CNS macrophage, the microglia. FEBS Lett. 223, 284-8.
    • (1987) FEBS Lett. , vol.223 , pp. 284-288
    • Colton, C.A.1    Gilbert, D.L.2
  • 15
    • 0028260210 scopus 로고
    • Cellular forms and functions of brain microglia
    • Davis, E. J., Foster, T. D. and Thomas, W. E. (1994). Cellular forms and functions of brain microglia. Brain Res. Bull. 34, 73-8.
    • (1994) Brain Res. Bull. , vol.34 , pp. 73-78
    • Davis, E.J.1    Foster, T.D.2    Thomas, W.E.3
  • 16
    • 0027354484 scopus 로고
    • Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
    • Dickson, D., Lee, S., Mattiace, L., Yen, S. and Brosnan, C. (1993). Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia 7, 75-83.
    • (1993) Glia , vol.7 , pp. 75-83
    • Dickson, D.1    Lee, S.2    Mattiace, L.3    Yen, S.4    Brosnan, C.5
  • 17
    • 0027981954 scopus 로고
    • Alterations of annexin expression in pathological neuronal and glial reactions
    • Eberhard, D., Brown, M. and VandenBerg, S. (1994). Alterations of annexin expression in pathological neuronal and glial reactions. Am. J. Path. 145, 640-649.
    • (1994) Am. J. Path. , vol.145 , pp. 640-649
    • Eberhard, D.1    Brown, M.2    Vandenberg, S.3
  • 19
    • 0030860260 scopus 로고    scopus 로고
    • Soluble macrophage factors trigger apoptosis in cultured hippocampal neurons
    • Flavin, M. P., Coughlin, K. and Ho, L. T. (1997). Soluble macrophage factors trigger apoptosis in cultured hippocampal neurons. Neuroscience 80, 437-448.
    • (1997) Neuroscience , vol.80 , pp. 437-448
    • Flavin, M.P.1    Coughlin, K.2    Ho, L.T.3
  • 20
    • 0029847804 scopus 로고    scopus 로고
    • Molecular mechanisms of microglial activation. A. Implications for regeneration and neurodegenerative diseases
    • Gebicke-Haerter, P., Van Calker, D., Nörenberg, W. and Illes, P. (1996). Molecular mechanisms of microglial activation. A. Implications for regeneration and neurodegenerative diseases. Neurochem. Int. 29, 1-12.
    • (1996) Neurochem. Int. , vol.29 , pp. 1-12
    • Gebicke-Haerter, P.1    Van Calker, D.2    Nörenberg, W.3    Illes, P.4
  • 22
    • 0022922108 scopus 로고
    • Characterization of amoeboid microglia isolated from developing mammalian brain
    • Guilian, D. and Baker, T. J. (1986). Characterization of amoeboid microglia isolated from developing mammalian brain. J. Neurosci. 6, 2163-2178.
    • (1986) J. Neurosci. , vol.6 , pp. 2163-2178
    • Guilian, D.1    Baker, T.J.2
  • 23
    • 0028023538 scopus 로고
    • An endothelial cell receptor for plasminogen/tissue plasminogen activator I. Identity with annexin II
    • Hajjar, K. A., Jacovina, A. T. and Chacko, J. (1994). An endothelial cell receptor for plasminogen/tissue plasminogen activator I. Identity with annexin II. J. Biol. Chem. 269, 21191-21197.
    • (1994) J. Biol. Chem. , vol.269 , pp. 21191-21197
    • Hajjar, K.A.1    Jacovina, A.T.2    Chacko, J.3
  • 24
    • 0033597411 scopus 로고    scopus 로고
    • Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator
    • Kim, Y.-H., Park, J.-H., Hong, S. and Koh, J.-Y. (1999). Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator. Science 284, 647-650.
    • (1999) Science , vol.284 , pp. 647-650
    • Kim, Y.-H.1    Park, J.-H.2    Hong, S.3    Koh, J.-Y.4
  • 25
    • 0029270425 scopus 로고
    • Microglia, the first line of defense in brain pathologies
    • Kreutzberg, G. W. (1995). Microglia, the first line of defense in brain pathologies. Arzneimittel Forschung, 45 (3a), 357-360.
    • (1995) Arzneimittel Forschung , vol.45 , Issue.3 A , pp. 357-360
    • Kreutzberg, G.W.1
  • 26
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg, G. W. (1996). Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19, 312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 27
    • 0025220976 scopus 로고
    • Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
    • Lawson, L., Perry, V., Dri, P. and Gordon, S. (1990). Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 39, 151-170.
    • (1990) Neuroscience , vol.39 , pp. 151-170
    • Lawson, L.1    Perry, V.2    Dri, P.3    Gordon, S.4
  • 28
    • 0027298505 scopus 로고
    • Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta
    • Lee, S., Liu, W., Dickson, D., Brosnan, C. and Berman, J. (1993). Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J. Immunol. 150, 2659-2667.
    • (1993) J. Immunol. , vol.150 , pp. 2659-2667
    • Lee, S.1    Liu, W.2    Dickson, D.3    Brosnan, C.4    Berman, J.5
  • 29
    • 0029976439 scopus 로고    scopus 로고
    • Neurocytopathic effects of β-amyloid-stimulated monocytes: A potential mechanism for central nervous system damage in Alzheimer's disease
    • London, J. A., Biegel, D. and Pachter, J. S. (1996). Neurocytopathic effects of β-amyloid-stimulated monocytes: A potential mechanism for central nervous system damage in Alzheimer's disease. Proc. Nat. Acad. Sci. USA 93, 4147-4152.
    • (1996) Proc. Nat. Acad. Sci. USA , vol.93 , pp. 4147-4152
    • London, J.A.1    Biegel, D.2    Pachter, J.S.3
  • 30
    • 0030066172 scopus 로고    scopus 로고
    • Molecular cloning of F4/80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein-linked transmembrane 7 hormone receptor family
    • McKnight, A. J., Macfarlane, A. J., Dri, P., Turley, L., Willis, A. C. and Gordon, S. (1996). Molecular cloning of F4/80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein-linked transmembrane 7 hormone receptor family. J. Biol. Chem. 271, 486-489.
    • (1996) J. Biol. Chem. , vol.271 , pp. 486-489
    • McKnight, A.J.1    Macfarlane, A.J.2    Dri, P.3    Turley, L.4    Willis, A.C.5    Gordon, S.6
  • 32
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merrill, J. E., Ignarro, L. J., Sherman, M. P., Melinek, J. and Lane, T. E. (1993). Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J. Immunol. 151, 2132-2141.
    • (1993) J. Immunol. , vol.151 , pp. 2132-2141
    • Merrill, J.E.1    Ignarro, L.J.2    Sherman, M.P.3    Melinek, J.4    Lane, T.E.5
  • 33
    • 0026731852 scopus 로고
    • Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues
    • Moestrup, S. K., Gliemann, J. and Pallesen, G. (1992). Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues. Cell Tissue Res. 269, 375-82.
    • (1992) Cell Tissue Res. , vol.269 , pp. 375-382
    • Moestrup, S.K.1    Gliemann, J.2    Pallesen, G.3
  • 34
    • 0029161781 scopus 로고
    • Glial cytokines in Alzheimer's Disease: Review and pathogenic implications
    • Mrak, R. E., Sheng, J. G. and Griffin, W. S. T. (1995). Glial cytokines in Alzheimer's Disease: Review and pathogenic implications. Hum. Pathol. 26, 816-823.
    • (1995) Hum. Pathol. , vol.26 , pp. 816-823
    • Mrak, R.E.1    Sheng, J.G.2    Griffin, W.S.T.3
  • 35
    • 0024955057 scopus 로고
    • Characterization of microglia isolated from a primary culture of embryonic rat brain by a simplified method
    • Nakajima, K., Hamanoue, M., Shimojo, M., Takei, N. and Kohsaka, S. (1989). Characterization of microglia isolated from a primary culture of embryonic rat brain by a simplified method. Biomed. Res. 10 (suppl. 3), 411-423.
    • (1989) Biomed. Res. , vol.10 , Issue.SUPPL. 3 , pp. 411-423
    • Nakajima, K.1    Hamanoue, M.2    Shimojo, M.3    Takei, N.4    Kohsaka, S.5
  • 36
    • 0026703642 scopus 로고
    • Production and secretion of plasminogen in cultured rat brain microglia
    • Nakajima, K., Tsuzaki, N., Nagata, K., Takemoto, N. and Kohsaka, S. (1992a). Production and secretion of plasminogen in cultured rat brain microglia. FEBS Lett. 308, 179-182.
    • (1992) FEBS Lett. , vol.308 , pp. 179-182
    • Nakajima, K.1    Tsuzaki, N.2    Nagata, K.3    Takemoto, N.4    Kohsaka, S.5
  • 37
    • 0026523080 scopus 로고
    • Microglia isolated from rat brain secrete a urokinase-type plasminogen activator
    • Nakajima, K., Tsuzaki, N., Shimojo, M., Hamanoue, M. and Kohsaka, S. (1992b). Microglia isolated from rat brain secrete a urokinase-type plasminogen activator. Brain Res. 577, 285-292.
    • (1992) Brain Res. , vol.577 , pp. 285-292
    • Nakajima, K.1    Tsuzaki, N.2    Shimojo, M.3    Hamanoue, M.4    Kohsaka, S.5
  • 40
    • 0025720505 scopus 로고
    • Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate
    • Piani, D., Frei, K., Do, K., Cuenod, M. and Fontana, A. (1991). Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate. Neurosci. Lett. 133, 159-162.
    • (1991) Neurosci. Lett. , vol.133 , pp. 159-162
    • Piani, D.1    Frei, K.2    Do, K.3    Cuenod, M.4    Fontana, A.5
  • 41
    • 0026743059 scopus 로고
    • Macrophage induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines
    • Piani, D., Spranger, M., Frei, K., Schaffner, A. and Fontana, A. (1992). Macrophage induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines. Eur. J. Immunol. 22, 2429-2436.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2429-2436
    • Piani, D.1    Spranger, M.2    Frei, K.3    Schaffner, A.4    Fontana, A.5
  • 42
    • 0027535364 scopus 로고
    • Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation
    • Qian, Z., Gilbert, M., Colicos, M., Kandel. E. and Kuhl, D. (1993). Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 361, 453-457.
    • (1993) Nature , vol.361 , pp. 453-457
    • Qian, Z.1    Gilbert, M.2    Colicos, M.3    Kandel, E.4    Kuhl, D.5
  • 43
    • 0023866970 scopus 로고
    • Tissue plasminogen activator mRNA in murine tissues
    • Rickles, R. J. and Strickland, S. (1988). Tissue plasminogen activator mRNA in murine tissues. FEBS Lett. 229, 100-106.
    • (1988) FEBS Lett. , vol.229 , pp. 100-106
    • Rickles, R.J.1    Strickland, S.2
  • 44
    • 0031963497 scopus 로고    scopus 로고
    • Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus
    • Rogove, A. and Tsirka, S. (1998). Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus. Curr. Biol. 8, 19-25.
    • (1998) Curr. Biol. , vol.8 , pp. 19-25
    • Rogove, A.1    Tsirka, S.2
  • 46
    • 0028289718 scopus 로고
    • Synaptic 5'-nucleotidase activity reflects lesion-induced sprouting within the adult rat dentate gyrus
    • Schoen, S. and Kreutzberg, G. (1994). Synaptic 5'-nucleotidase activity reflects lesion-induced sprouting within the adult rat dentate gyrus. Exp. Neurol. 127, 106-118.
    • (1994) Exp. Neurol. , vol.127 , pp. 106-118
    • Schoen, S.1    Kreutzberg, G.2
  • 47
    • 0024424509 scopus 로고
    • Structural domains of human tissue-type plasminogen activator that confer stimulation by heparin
    • Stein, P. L., van Zonneveld, A. J., Pannakoek, H. and Strickland, S. (1989). Structural domains of human tissue-type plasminogen activator that confer stimulation by heparin. J. Biol. Chem. 264, 15441-15444.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15441-15444
    • Stein, P.L.1    Van Zonneveld, A.J.2    Pannakoek, H.3    Strickland, S.4
  • 49
    • 0027214034 scopus 로고
    • Microglial-neuronal interactions
    • Streit, W. (1993). Microglial-neuronal interactions. J. Clin. Neuroanat. 6, 261-266.
    • (1993) J. Clin. Neuroanat. , vol.6 , pp. 261-266
    • Streit, W.1
  • 50
    • 0027464886 scopus 로고
    • Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro
    • Thanos, S., Mey, J. and Wild, M. (1993). Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro. J. Neurosci. 13, 455-466.
    • (1993) J. Neurosci. , vol.13 , pp. 455-466
    • Thanos, S.1    Mey, J.2    Wild, M.3
  • 51
    • 0029088484 scopus 로고
    • Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator
    • Tsirka, S. E., Gualandris, A., Amaral, D. G. and Strickland, S. (1995). Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature 377, 340-344.
    • (1995) Nature , vol.377 , pp. 340-344
    • Tsirka, S.E.1    Gualandris, A.2    Amaral, D.G.3    Strickland, S.4
  • 52
  • 53
    • 0031021357 scopus 로고    scopus 로고
    • An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus
    • Tsirka, S., Rogove, A., Bugge, T., Degen, J. and Strickland, S. (1997). An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. J. Neurosci. 17, 543-552.
    • (1997) J. Neurosci. , vol.17 , pp. 543-552
    • Tsirka, S.1    Rogove, A.2    Bugge, T.3    Degen, J.4    Strickland, S.5
  • 55
    • 0023646314 scopus 로고
    • Amiloride selectively inhibits the urokinase-type plasminogen activator
    • Vassalli, J. and Belin, D. (1987). Amiloride selectively inhibits the urokinase-type plasminogen activator. FEBS Lett. 214, 187-191.
    • (1987) FEBS Lett. , vol.214 , pp. 187-191
    • Vassalli, J.1    Belin, D.2
  • 56
    • 0028923898 scopus 로고
    • Complement and cytokine gene expression in cultured microglia derived from postmortem human brains
    • Walker, D., Kim, S. and McGeer, P. (1995). Complement and cytokine gene expression in cultured microglia derived from postmortem human brains. J. Neurosci. Res. 40, 478-493.
    • (1995) J. Neurosci. Res. , vol.40 , pp. 478-493
    • Walker, D.1    Kim, S.2    McGeer, P.3
  • 57
    • 0028244469 scopus 로고
    • Activation of adult human derived microglia by myelin phagocytosis in vitro
    • Williams, K., Ulvestad, E., Waage, A., Antel, J. P. and McLaurin, J. (1994). Activation of adult human derived microglia by myelin phagocytosis in vitro. J. Neurosci. Res. 38, 433-443.
    • (1994) J. Neurosci. Res. , vol.38 , pp. 433-443
    • Williams, K.1    Ulvestad, E.2    Waage, A.3    Antel, J.P.4    McLaurin, J.5
  • 58
    • 0029121104 scopus 로고
    • Microglia as a unique cellular target in the treatment of stroke: Potential neurotoxic mediators produced by activated microglia
    • Wood, P. L. (1995). Microglia as a unique cellular target in the treatment of stroke: Potential neurotoxic mediators produced by activated microglia. Neurol. Res. 17, 242-248.
    • (1995) Neurol. Res. , vol.17 , pp. 242-248
    • Wood, P.L.1
  • 59
    • 0029921020 scopus 로고    scopus 로고
    • Neuron-microglia interactions in vitro
    • Zhang, S. and Fedoroff, S. (1996). Neuron-microglia interactions in vitro. Acta Neuropathol. 91, 385-395.
    • (1996) Acta Neuropathol. , vol.91 , pp. 385-395
    • Zhang, S.1    Fedoroff, S.2


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