메뉴 건너뛰기




Volumn 163, Issue 11, 1999, Pages 6114-6122

Compromised virus control and augmented perforin-mediated immunopathology in IFN-γ-deficient mice infected with lymphocytic choriomeningitis virus

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; PERFORIN;

EID: 0033485408     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (76)

References (50)
  • 3
    • 0031307852 scopus 로고    scopus 로고
    • + T cells clear influenza virus by perforin or Fas-dependent processes
    • + T cells clear influenza virus by perforin or Fas-dependent processes. J. Immunol. 159:5197.
    • (1997) J. Immunol. , vol.159 , pp. 5197
    • Topham, D.J.1    Tripp, R.A.2    Doherty, P.C.3
  • 4
    • 0030218260 scopus 로고    scopus 로고
    • Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses
    • Kagi, D., and H. Hengartner. 1996. Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses. Curr. Opin. Immunol. 8:472.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 472
    • Kagi, D.1    Hengartner, H.2
  • 5
    • 0027255999 scopus 로고
    • T cell-dependent IFN-γ exerts an antiviral effect in the central nervous system but not in peripheral solid organs
    • Kundig, T. M., H. Hengartner, and R. M. Zinkernagel. 1993. T cell-dependent IFN-γ exerts an antiviral effect in the central nervous system but not in peripheral solid organs. J. Immunol. 150:2316.
    • (1993) J. Immunol. , vol.150 , pp. 2316
    • Kundig, T.M.1    Hengartner, H.2    Zinkernagel, R.M.3
  • 6
    • 0026525006 scopus 로고
    • γ interferon-dependent clearance of cytomegalovirus infection in salivary glands
    • Lucin, P., I. Pavic, B. Polic, S. Jonjic, and U. H. Koszinowski. 1992. γ interferon-dependent clearance of cytomegalovirus infection in salivary glands. J. Virol. 66:1977.
    • (1992) J. Virol. , vol.66 , pp. 1977
    • Lucin, P.1    Pavic, I.2    Polic, B.3    Jonjic, S.4    Koszinowski, U.H.5
  • 8
    • 0031041001 scopus 로고    scopus 로고
    • The cytotoxic T-lymphocyte response to Sendai virus is unimpaired in the absence of γ interferon
    • Mo, X. Y., R. A. Tripp, M. Y. Sangster, and P. C. Doherty. 1997. The cytotoxic T-lymphocyte response to Sendai virus is unimpaired in the absence of γ interferon. J. Virol. 71:1906.
    • (1997) J. Virol. , vol.71 , pp. 1906
    • Mo, X.Y.1    Tripp, R.A.2    Sangster, M.Y.3    Doherty, P.C.4
  • 12
    • 0029061716 scopus 로고
    • Theiler's virus infection of 129Sv mice that lack the interferon α/β or interferon γ receptors
    • Fiette, L., C. Aubert, U. Muller, S. Huang, M. Aguet, M. Brahic, and J. F. Bureau. 1995. Theiler's virus infection of 129Sv mice that lack the interferon α/β or interferon γ receptors. J. Expn. Med. 181:2069.
    • (1995) J. Expn. Med. , vol.181 , pp. 2069
    • Fiette, L.1    Aubert, C.2    Muller, U.3    Huang, S.4    Aguet, M.5    Brahic, M.6    Bureau, J.F.7
  • 13
    • 0028100452 scopus 로고
    • Control of acute cutaneous herpes simplex virus infection: T cell-mediated viral clearance is dependent upon interferon-γ (IFN-γ)
    • Smith, P. M., R. M. Wolcott, R. Chervenak, and S. R. Jennings. 1994. Control of acute cutaneous herpes simplex virus infection: T cell-mediated viral clearance is dependent upon interferon-γ (IFN-γ). Virology 202:76.
    • (1994) Virology , vol.202 , pp. 76
    • Smith, P.M.1    Wolcott, R.M.2    Chervenak, R.3    Jennings, S.R.4
  • 14
    • 0029949634 scopus 로고    scopus 로고
    • Exacerbated viral hepatitis in IFN-γ receptor-deficient mice is not suppressed by IL-12
    • Schijns, V. E., C. M. Wierda, M. van Hoeij, and M. C. Horzinek. 1996. Exacerbated viral hepatitis in IFN-γ receptor-deficient mice is not suppressed by IL-12. J. Immunol. 157:815.
    • (1996) J. Immunol. , vol.157 , pp. 815
    • Schijns, V.E.1    Wierda, C.M.2    Van Hoeij, M.3    Horzinek, M.C.4
  • 15
    • 0028844073 scopus 로고
    • An essential role for type 1 interferon-γ in terminating persistent viral infection
    • Tishon, A., H. Lewicki, G. Rall, M. Von Herrath, and M. B. Oldstone. 1995. An essential role for type 1 interferon-γ in terminating persistent viral infection. Virology 212:244.
    • (1995) Virology , vol.212 , pp. 244
    • Tishon, A.1    Lewicki, H.2    Rall, G.3    Von Herrath, M.4    Oldstone, M.B.5
  • 17
    • 0031575822 scopus 로고    scopus 로고
    • Low-affinity cytotoxic T-lymphocytes require IFN-γ to clear an acute viral infection
    • Von Herrath, M. G., B. Coon, and M. B. Oldstone. 1997. Low-affinity cytotoxic T-lymphocytes require IFN-γ to clear an acute viral infection. Virology 229:349.
    • (1997) Virology , vol.229 , pp. 349
    • Von Herrath, M.G.1    Coon, B.2    Oldstone, M.B.3
  • 18
    • 0030986358 scopus 로고    scopus 로고
    • (+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers
    • RM
    • (+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers. Proc. Natl. Acad. Sci. USA 94:6874.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6874
    • Planz, O.1    Ehl, S.2    Furrer, E.3    Horvath, E.4    Brundler, M.A.5    Hengartner, H.Z.6
  • 19
    • 0024335914 scopus 로고
    • Mechanism of recovery from acute virus infection. VIII. Treatment of lymphocytic choriomeningitis virus-infected mice with anti-interferon-γ monoclonal antibody blocks generation of virus-specific cytotoxic T lymphocytes and virus elimination
    • Wille, A., A. Gessner, H. Lother, and F. Lehmann-Grube. 1989. Mechanism of recovery from acute virus infection. VIII. Treatment of lymphocytic choriomeningitis virus-infected mice with anti-interferon-γ monoclonal antibody blocks generation of virus-specific cytotoxic T lymphocytes and virus elimination. Eur. J. Immunol. 19:1283.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 1283
    • Wille, A.1    Gessner, A.2    Lother, H.3    Lehmann-Grube, F.4
  • 20
    • 0030068156 scopus 로고    scopus 로고
    • Modulation by γ interferon of antiviral cell-mediated immune responses in vivo
    • Utermohlen, O., A. Dangel. A. Tarnok, and F. Lehmann-Grube. 1996. Modulation by γ interferon of antiviral cell-mediated immune responses in vivo. J. Virol. 70:1521.
    • (1996) J. Virol. , vol.70 , pp. 1521
    • Utermohlen, O.1    Dangel, A.2    Tarnok, A.3    Lehmann-Grube, F.4
  • 21
    • 0027400726 scopus 로고
    • Multiple defects of immune cell function in mice with disrupted interferon-γ genes
    • Dalton, D. K., S. Pitts-Meek, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259:1739.
    • (1993) Science , vol.259 , pp. 1739
    • Dalton, D.K.1    Pitts-Meek, S.2    Keshav, S.3    Figari, I.S.4    Bradley, A.5    Stewart, T.A.6
  • 22
    • 0032526197 scopus 로고    scopus 로고
    • Role of interferon-γ in the pathogenesis of LCMV-induced meningitis: Unimpaired leukocyte recruitment, but deficient macrophage activation in interferon-γ knock-out mice
    • Nansen, A., J. P. Christensen, C. Ropke, O. Marker, A. Scheynius, and A. R. Thomsen. 1998. Role of interferon-γ in the pathogenesis of LCMV-induced meningitis: unimpaired leukocyte recruitment, but deficient macrophage activation in interferon-γ knock-out mice. J. Neuroimmunol. 86:202.
    • (1998) J. Neuroimmunol. , vol.86 , pp. 202
    • Nansen, A.1    Christensen, J.P.2    Ropke, C.3    Marker, O.4    Scheynius, A.5    Thomsen, A.R.6
  • 23
    • 0020071647 scopus 로고
    • The immune response of the mouse to lymphocytic choriomeningitis virus. II. Active suppression of cell-mediated immunity by infection with high virus doses
    • Lehmann-Grube, F., J. Cihak, M. Varho, and R. Tijerina. 1982. The immune response of the mouse to lymphocytic choriomeningitis virus. II. Active suppression of cell-mediated immunity by infection with high virus doses. J. Gen. Virol. 58:223.
    • (1982) J. Gen. Virol. , vol.58 , pp. 223
    • Lehmann-Grube, F.1    Cihak, J.2    Varho, M.3    Tijerina, R.4
  • 24
    • 0024411114 scopus 로고
    • Enhanced virus replication and inhibition of lymphocytic choriomeningitis virus disease in anti-γ interferon-treated mice
    • Leist, T. P., M. Eppler, and R. M. Zinkernagel. 1989. Enhanced virus replication and inhibition of lymphocytic choriomeningitis virus disease in anti-γ interferon-treated mice. J. Virol. 63:2813.
    • (1989) J. Virol. , vol.63 , pp. 2813
    • Leist, T.P.1    Eppler, M.2    Zinkernagel, R.M.3
  • 25
    • 0028200690 scopus 로고
    • Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-α/β
    • Sandberg, K., P. Kemper, A. Stalder, J. Zhang, M. V. Hobbs, J. L. C. Whitton, and I. L. Campbell. 1994. Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-α/β. J. Immunol. 153:220.
    • (1994) J. Immunol. , vol.153 , pp. 220
    • Sandberg, K.1    Kemper, P.2    Stalder, A.3    Zhang, J.4    Hobbs, M.V.5    Whitton, J.L.C.6    Campbell, I.L.7
  • 27
    • 0030266708 scopus 로고    scopus 로고
    • Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice
    • Thomsen, A. R., J. Johansen, O. Marker, and J. P. Christensen. 1996. Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice. J. Immunol. 157:3074.
    • (1996) J. Immunol. , vol.157 , pp. 3074
    • Thomsen, A.R.1    Johansen, J.2    Marker, O.3    Christensen, J.P.4
  • 28
    • 3643064537 scopus 로고    scopus 로고
    • CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus
    • Thomsen, A. R., A. Nansen, J. P. Christensen, S. O. Andreasen, and O. Marker. 1998. CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus. J. Immunol. 161:4583.
    • (1998) J. Immunol. , vol.161 , pp. 4583
    • Thomsen, A.R.1    Nansen, A.2    Christensen, J.P.3    Andreasen, S.O.4    Marker, O.5
  • 30
    • 0015633573 scopus 로고
    • Studies on cell-mediated immunity to lymphocytic choriomeningitis virus in mice
    • Marker, O., and M. Volkert. 1973. Studies on cell-mediated immunity to lymphocytic choriomeningitis virus in mice. J. Exp. Med. 137:1511.
    • (1973) J. Exp. Med. , vol.137 , pp. 1511
    • Marker, O.1    Volkert, M.2
  • 31
    • 0024338556 scopus 로고
    • + lymphocytes during an acute viral infection
    • Published erratum appears in 1989, J. Exp. Med 170:2191
    • + lymphocytes during an acute viral infection. [Published erratum appears in 1989, J. Exp. Med 170:2191.] J. Exp. Med. 169: 2159.
    • (1989) J. Exp. Med. , vol.169 , pp. 2159
    • Young, L.H.1    Klavinskis, L.S.2    Oldstone, M.B.3    Young, J.D.4
  • 32
    • 0028205597 scopus 로고
    • Changes in cell adhesion molecule expression on T cells associated with systemic virus infection
    • Andersson, E. C., J. P. Christensen, O. Marker, and A. R. Thomsen. 1994. Changes in cell adhesion molecule expression on T cells associated with systemic virus infection. J. Immunol. 152:1237.
    • (1994) J. Immunol. , vol.152 , pp. 1237
    • Andersson, E.C.1    Christensen, J.P.2    Marker, O.3    Thomsen, A.R.4
  • 35
    • 0025787430 scopus 로고
    • Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure
    • Odermatt, B., M. Eppler, T. P. Leist, H. Hengartner, and R. M. Zinkernagel. 1991. Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure. Proc. Natl. Acad. Sci. USA 88:8252.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8252
    • Odermatt, B.1    Eppler, M.2    Leist, T.P.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 36
    • 0033555391 scopus 로고    scopus 로고
    • A role for perforin in activation-induced T cell death in vivo: Increased expansion of allogeneic perforin-deficient T cells in SCID mice
    • Spaner, D., K. Raju, B. Rabinovich, and R. G. Miller. 1999. A role for perforin in activation-induced T cell death in vivo: increased expansion of allogeneic perforin-deficient T cells in SCID mice. J. Immunol. 162:1192.
    • (1999) J. Immunol. , vol.162 , pp. 1192
    • Spaner, D.1    Raju, K.2    Rabinovich, B.3    Miller, R.G.4
  • 37
  • 38
    • 0024828495 scopus 로고
    • Cytotoxic T lymphocyte control of acute lymphocytic choriomeningitis virus infection: Interferon γ, but not tumor necrosis factor α, displays antiviral activity in vivo
    • Klavinskis, L. S., R. Geckeler, and M. B. Oldstone. 1989. Cytotoxic T lymphocyte control of acute lymphocytic choriomeningitis virus infection: interferon γ, but not tumor necrosis factor α, displays antiviral activity in vivo. J. Gen. Virol. 70:3317.
    • (1989) J. Gen. Virol. , vol.70 , pp. 3317
    • Klavinskis, L.S.1    Geckeler, R.2    Oldstone, M.B.3
  • 40
    • 0023196212 scopus 로고
    • Phenotypic analysis of the inflammatory exudate in murine lymphocytic choriomeningitis
    • Ceredig, R., J. E. Allan, Z. Tabi, F. Lynch, and P. C. Doherty. 1987. Phenotypic analysis of the inflammatory exudate in murine lymphocytic choriomeningitis. J. Exp. Med. 165:1539.
    • (1987) J. Exp. Med. , vol.165 , pp. 1539
    • Ceredig, R.1    Allan, J.E.2    Tabi, Z.3    Lynch, F.4    Doherty, P.C.5
  • 41
    • 0027488067 scopus 로고
    • Inhibition of viral replication by interferon-γ-induced nitric oxide synthase
    • Karupiah, G., Q. W. Xie, R. M. Buller, C. Nathan, C. Duarte, and J. D. MacMicking. 1993. Inhibition of viral replication by interferon-γ-induced nitric oxide synthase. Science 261:1445.
    • (1993) Science , vol.261 , pp. 1445
    • Karupiah, G.1    Xie, Q.W.2    Buller, R.M.3    Nathan, C.4    Duarte, C.5    MacMicking, J.D.6
  • 42
    • 0031446517 scopus 로고    scopus 로고
    • A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro
    • Ehl, S., P. Klenerman, P. Aichele, H. Hengartner, and R. M. Zinkernagel. 1997. A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro. Eur. J. Immunol. 27:3404.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3404
    • Ehl, S.1    Klenerman, P.2    Aichele, P.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 45
    • 0027420560 scopus 로고
    • Lymphocytic choriomeningitis virus induces a chronic wasting disease in mice lacking class I major histocompatibilily complex glycoproteins
    • Doherty, P. C., S. Hou, and P. J. Southern. 1993. Lymphocytic choriomeningitis virus induces a chronic wasting disease in mice lacking class I major histocompatibilily complex glycoproteins. J. Neuroimmunol. 46:11.
    • (1993) J. Neuroimmunol. , vol.46 , pp. 11
    • Doherty, P.C.1    Hou, S.2    Southern, P.J.3
  • 46
    • 0024323042 scopus 로고
    • Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated
    • Leist, T., A. Althage, E. Haenseler, H. Hengartner, and R. M. Zinkernagel. 1989. Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated. J. Exp. Med. 170:269.
    • (1989) J. Exp. Med. , vol.170 , pp. 269
    • Leist, T.1    Althage, A.2    Haenseler, E.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 47
    • 0028169445 scopus 로고
    • IFN-γ receptor-deficient mice generate antiviral Th1-characteristic cytokine profiles but altered antibody responses
    • Schijns, V. E., B. L. Haagmans, E. O. Rijke, S. Huang, M. Aguet, and M. C. Horzinek. 1994. IFN-γ receptor-deficient mice generate antiviral Th1-characteristic cytokine profiles but altered antibody responses. J. Immunol. 153: 2029.
    • (1994) J. Immunol. , vol.153 , pp. 2029
    • Schijns, V.E.1    Haagmans, B.L.2    Rijke, E.O.3    Huang, S.4    Aguet, M.5    Horzinek, M.C.6
  • 48
    • 0028177650 scopus 로고
    • 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype
    • 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype. J. Immunol. 153:1246.
    • (1994) J. Immunol. , vol.153 , pp. 1246
    • Sarawar, S.R.1    Sangster, M.2    Coffman, R.L.3    Doherty, P.C.4
  • 49
    • 0027971249 scopus 로고
    • + T cells in cell-mediated immunity to LCMV: Studies in MHC class I and class II deficient mice
    • + T cells in cell-mediated immunity to LCMV: studies in MHC class I and class II deficient mice. Scand. J. Immunol. 40:373.
    • (1994) Scand. J. Immunol. , vol.40 , pp. 373
    • Christensen, J.P.1    Marker, O.2    Thomsen, A.R.3
  • 50
    • 85045228806 scopus 로고    scopus 로고
    • + T cell mediated protection against a lethal outcome of systemic infection with vesicular stomatitis virus requires CD40 ligand expression, but not interferon-γ or interteukin-4
    • In press
    • + T cell mediated protection against a lethal outcome of systemic infection with vesicular stomatitis virus requires CD40 ligand expression, but not interferon-γ or interteukin-4. Int. Immunol. In press.
    • (1999) Int. Immunol.
    • Anderson, C.1    Jensen, T.2    Nauseu, A.3    Marker, O.4    Thomsen, A.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.