Gamma interferon is not essential for recovery from acute infection with murine gammaherpesvirus 68

Journal of Virology

Volumn 71, Issue 5, 1997, Pages 3916-3921

  Sarawar, Sally R ^a,b   Cardin, Rhonda D ^a   Brooks, James W ^a   Mehrpooya, Mehdi ^a   Hamilton Easton, Anne Marie ^a   Mo, Xiao Yan ^a,c   Doherty, Peter C ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b BD Technologies   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HERPES VIRUS; HERPES VIRUS INFECTION; IMMUNE RESPONSE; INFECTION CONTROL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030971472     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.5.3916-3921.1997     Document Type: Article

References (20)

1. Allan, W., Z. Tabi, A. Cleary, and P. C. Doherty. 1990. Cellular events in the lymph node and lung of mice with influenza: consequences of depleting CD4+ T cells. J. Immunol. 144:3980-3984.
2. Blaskovic, D., M. Stancekova, J. Svobodova, and J. Mistrikova. 1980. Isolation of five strains of herpesviruses from two species of free living small rodents. Acta Virol. 24:468.
3. Bouley, D. M., S. Kanangat, W. Wire, and B. T. Rouse. 1995. Characterization of herpes simplex virus type-1 infection and herpetic stromal keratitis development in IFN-γ knockout mice. J. Immunol. 155:3964-3971.
4. Cardin, R. D., J. W. Brooks, S. R. Sarawar, and P. C. Doherty. 1996. Progressive loss of CD8+ T cell-mediated control of a γ-herpesvirus in the absence of CD4+ T cells. J. Exp. Med. 184:863-871.
5. Dalton, D. K., S. Pitts-Meek, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cells function in mice with disrupted interferon-γ genes. Science 259:1739-1742.
6. Efstathiou, S., Y. M. Ho, S. Hall, C. J. Styles, S. D. Scott, and U. A. Gompels. 1990. Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri. J. Gen. Virol. 71:1365-1372.
7. Ehtisham, S., N. P. Sunil-Chandra, and A. A. Nash. 1993. Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells. J. Virol. 67:5247-5252.
8. Gajewski, T. F., J. Joyce, and F. W. Fitch. 1989. Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma. J. Immunol. 143:15-22.
9. Graham, M. M., D. K. Dalton, D. Giltinan, V. L. Braciale, T. A. Stewart, and T. J. Braciale. 1993. Response to influenza infection in mice with a targeted disruption in the IFN-γ gene. J. Exp. Med. 178:1725-1738.
10. Huang, S., W. Hendriks, A. Althage, S. Hemmi, H. Bluethman, R. Kamijo, J. Vilcek, R. M. Zinkernagel, and M. Aguet. Immune response in mice that lack the interferon-γ receptor. Science 259:1742-1745.
11. Lucin, P., I. Pavic, B. Polic, S. Jonjic, and U. H. Koszinowski. 1992. Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands. J. Virol. 66:1977-1984.
12. Sarawar, S. R., R. D. Cardin, J. W. Brooks, M. Mehrpooya, R. A. Tripp, and P. C. Doherty. 1996. Cytokine production in the immune response to murine gammaherpesvirus 68. J. Virol. 70:3264-3268.
13. Sarawar, S. R., and P. C. Doherty. 1994. Concurrent production of interleukin-2, interleukin-10, and gamma interferon in the regional lymph nodes of mice with influenza pneumonia. J. Virol. 68:3112-3119.
14. Sarawar, S. R., M. Y. Sangster, R. L. Coffman, and P. C. Doherty. Administration of anti-IFN-γ-antibody to β-2 microglobulin (-/-) mice delays influenza virus clearance but does not switch the response to a TH2 phenotype. J. Immunol. 153:1246-1253.
15. Schijns, V. E., B. L. Haagmans, E. O. Rijke, S. Huang, M. Aguet, and M. C. Horzinek. 1994. IFN-gamma receptor-deficient mice generate antiviral Th1-characteristic cytokine profiles but altered antibody responses. J. Immunol. 153:2029-2037.
16. Smith, P. M., R. M. Wolcott, R. Chervenak, and S. R. Jennings. 1994. Control of acute cutaneous herpes simplex virus infection: T cell-mediated viral clearance is dependent upon interferon-gamma (IFN-gamma). Virology 202:76-88.
17. Sunil-Chandra, N. P., S. Estathiou, and A. A. Nash. 1993. Interactions of murine gammaherpesvirus 68 with B and T cell lines. Virology 193:825-833.
18. Sunil-Chandra, N. P., S. Efstathiou, J. Arno, and A. A. Nash. 1992. Virological and pathological features of mice infected with murine gamma-herpesvirus 68. J. Gen. Virol. 73:2347-2356.
19. Sunil-Chandra, N. P., S. Efstathiou, and A. A. Nash. 1992. Murine gamma-herpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo. J. Gen. Virol. 73:3275-3279.
20. Wille A., A. Gessner, H. Lother, and F. Lehmann-Grube. 1989. Mechanism of recovery from acute virus infection. VIII. Treatment of lymphocytic choriomeningitis virus infected mice with anti-interferon-γ monoclonal Ab blocks generation of virus-specific cytotoxic T lymphocytes and virus elimination. Eur. J. Immunol. 19:1283-1291.