Pathogenesis of Alzheimer's disease and dementia

Revue Neurologique

Volumn 155, Issue SUPPL. 4, 1999, Pages

  Bugiani, O ^a  

^a DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CYTOSKELETON PROTEIN; TAU PROTEIN;

ALZHEIMER DISEASE; CYTOSKELETON; HISTOPATHOLOGY; HUMAN; NEOCORTEX; NERVE CELL DEGENERATION; NEUROFILAMENT; REVIEW; AGED; AGING; BRAIN; METABOLISM; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; PATHOLOGY; PHYSIOLOGY;

AGED; AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; BRAIN; CYTOSKELETAL PROTEINS; HUMANS; NERVE DEGENERATION; NEUROFIBRILLARY TANGLES; TAU PROTEINS;

EID: 0033428613     PISSN: 00353787     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (31)

1. BUGIANI O., GIACCONE G., VERGA L., POLLO B., FRANGIONE B., FARLOW M.R., TAGLIAVINI F., GHETTI B. (1993). βPP participates in PrP-amyloid plaques in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. J. Neuropathol. Exp. Neurol. 52: 64-70.
2. BUGIANI O., PADOVANI A., MAGONI M., ANDORA G., SGARZI M., SAVOIARDO M., BIZZI A., GIACCONE G., ROSSI G., TAGLIAVINI F. (1998). An Italian type of HCHWA. Neurobiol. Aging 19: S238.
3. CITRON M., WESTAWAY D., XIA W., CARLSON G., DIEHL T., LAVESQUE G., JOHNSON-WOOD K., LEE M., SEUBERT P., DAVIS A., KHOLO-DENKO D., MOTTER R., SHERRINGTON R., PERRY B., YAO H., STROME R., LIEBERBURG I., ROMMENS J., KIM S., SCHENK D., FRASER P., STGEORGE-HYSLOP P., SELKOE D.J. (1997). Mutant presenilines of Alzheimer's disease increase production of 42-residue amyloid β protein in both transfected cells and transgenic mice. Nature Med. 3: 67-72.
4. COTMAN C.W., Su J.H. (1996). Mechanisms of neuronal death in Alzheimer's disease. Brain Pathol 6: 493-506.
5. DELACOURTE A., BUÉE L. (1997). Normal and pathological tau proteins as factors of microtubule assembly. Int. Rev. Cytol. 171: 167-223.
6. FORLONI G., TAGLIAVINI F., BUGIANI O., SALMONA M. (1996). Amyloid in Alzheimer's disease and prion-related encephalopathies: studies with synthetic peptides. Progr. Neurobiol. 49: 287-315.
7. FOSTER N.L., CHASE T.N., FEDIO P., PATRONAS N.J., BROOKS R.A., DICHIRO G. (1983). Alzheimer's disease: focal cortical changes shown in positron emission tomography. Neurology 33: 961-965.
8. GIACCONE G., PEDROTTI B., MIGHELI A., VERGA L., PEREZ J., RACAGNI G., SMITH M.A., PERRY G., DE GIOIA L., SELVAGGINI C., SALMONA M., GHISO J., FRANGIONE B., ISLAM K., BUGIANI O., TAGLIAVINI F. (1996). βPP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease. Am. J. Pathol. 148: 79-87.
9. GLENNER G.G., WONG C.W. (1984). Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid. Biochem. Biophys. Res. Commun. 120: 885-890.
10. GUSTAFSON L. (1999). Frontotemporal dementia and Pick's disease. Rev. Neurol. (Paris), this issue.
11. HARDY J. (1992). An "anatomical cascade hypothesis" for Alzheimer's disease. Trends Neurosci. 15: 200-201.
12. HARDY J. (1997). Amyloid, the presenilines, and Alzheimer's disease. Trends Neurosci. 20: 154-159.
13. HOF P.R., MORRISON J.H. (1994) The cellular basis of cortical disconnection in Alzheimer disease and related dementing conditions. In Terry R.D., Katzmann R., Bick K.L. (eds). Alzheimer disease (Lippincott-Raven, Philadelphia, New York) pp 197-229.
14. IWATSUBO T., ODAKA A., SUZUKI N., MIZUSAWA H., NUKINA N., IHARA Y. (1994). Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: evidence that an iunitially deposition species is Aβ42(43). Neuron 13: 45-53.
15. JARRET J.T., BERGER E.P., LANSBURY P.T. (1993). The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 32: 4693-4697.
16. KAMMESHEIDT A., BOYCE F.M., SPANOYANNIS A.F., CUMMINGS B.J., ORTEGÓN M., COTMAN C., VAUGHT J.L., NEVE R.L. (1992). Deposition of β/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain. Proc. Natl. Acad. Sci. USA 89: 10857-10861.
17. KANG J., LEMAIRE H.-G., UNTERBECK A., SALBAUM M., MASTERS C.L., GRZESCHIK K.H., MULTHAUP G., BEYREUTHER K., MULLER-HILL B. (1987). The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736.
18. LORENZO A., YANKNER B.A. (1994). β-amyloid neurotoxicity requires fibril formation and is inhibited by Congo red. Proc. Natl Acad. Sci. USA 91: 12243-12247.
19. MARX J. (1996). Searching for drugs that combat Alzheimer's, Science 273: 50-53.
20. NALBANTOGLU J., TIRADO-SANTIAGO G., LAHSAÏNL A., POIRIER J., GONCALVES O., VERGE G., MOMOLI F., WELNER S.A., MASSICOTTE G., JULIEN J.-P., SHAPIRO M.L. (1997). Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precurson protein. Nature 387: 500-505.
21. RAPOPORT S.I. (1988). Brain evolution and Alzheimer's disease. Rev. Neurol. (Paris) 144: 79-90.
22. RITCHIE K., KILDEA D. (1995). Is senile dementia "age-related" or "ageing-related"? - evidence from meta-analysis of dementia prevalence in the oldest old. Lancet 346: 931-934.
23. SAUNDERS A.M., STRITTMATTER W.I., SCHMECHEL D., STGEORGE-HYSLOP P.I., PERICAK-VANCE M.A., JOO S.H., ROSI B.L., GUSELLA J.F., CRAPPER-MCLACHLAN D.R., ALBERTS M.J., HULETTE C., CRAIN B., GOLDGABER D., ROSES A.D. (1993). Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43: 1467-1472.
24. SELKOE D.J. (1991). Amyloid β protein precursor and the pathogenesis of Alzheimer's disease. Cell 58: 611-612
25. SELKOE D.J. (1997). Alzheimer's disease: genotypes, phenotypes, and treatments. Science 275: 630-631.
26. SPILLANTINI M.G., GOEDERT M. (1998). Tau protein pathology in neurodegenerative diseases. Trends Neurosci. 21: 428-433.
27. SPREAFICO R., FRASSONI C., ARCELLI P., SELVAGGIO M., DE BIASI S. (1995). In situ labeling of apoptotic cell death in the cerebral cortex and thalamus of rats during development. J Comp. Neur. 363: 281-295.
28. 717) mutants. Science 264: 1336-1340.
29. TERRY R.D. (1996) The pathogenesis of Alzheimer disease. An alternative to the amyloid hypothesis. J. Neuropathol. Exp. Neurol. 55: 1023-1025.
30. WISNIEWSKI T., GHISO J., FRANGIONE B. (1997). Biology of Aβ amyloid in Alzheimer's disease. Neurobiol. Dis. 4: 313-318
31. YANKNER B.A., DAWES L.R., FRASER S., VILLA-KOMAROFF L., OSTER-GRANITE M.L., NEVE R.L. (1989). Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. Science 245: 417-420.