Progress and potential of genetic susceptibility to environmental toxicants

Scandinavian Journal of Work, Environment and Health

Volumn 25, Issue 6, 1999, Pages 537-540

  Haugen, Aage ^a  

^a NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

Author keywords

Gene environment interaction; Microchips; Molecular epidemiology; Polymorphism; Single nucleotide polymorphisms

Indexed keywords

TOXIC SUBSTANCE;

GENETIC STRUCTURE; HEALTH RISK; RISK FACTOR; TOXICITY;

DNA POLYMORPHISM; ENVIRONMENTAL EXPOSURE; GENETIC EPIDEMIOLOGY; GENETIC SUSCEPTIBILITY; GENETIC TOXICOLOGY; HUMAN; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0033385792     PISSN: 03553140     EISSN: None     Source Type: Journal    
DOI: 10.5271/sjweh.477     Document Type: Short Survey

References (20)

1. Ponder B. Genetic testing for cancer risk. Science 1997;278:1050-54.
2. International Agency for Research on Cancer (IARC). Metabolic polymorphisms and susceptibility to cancer. Lyon: IARC, 1999. IARC scientific publication, no 148.
3. Blacker D, Tanzi RE. The genetics of Alzheimer disease: current status and future prospects. Arch Neurol 1998;55:294-96.
4. Wormhoudt LW, Commandeur JNM, Vermeuten NPE. Genetic polymorphism of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity. Crit Rev Toxicol 1999;29:59-124.
5. Perera FP. Environment and cancer: who are susceptible? Science 1997;278:1068-73.
6. Rebbeck TR. Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility. Cancer Epidemiol Biomarkers Prev 1997;6:733-43.
7. Spivac SD, Fasco MJ, Walker VE, Kaminsky LS. The molecular epidemiology of lung cancer. Crit Rev Toxocol 1997;27:319-65.
8. Okada T, Kawashima K, Fukushi S, Minakuchi T, Nishimura S. Association between a cytochrome P450 CYP1A1 genotype and incidence of lung cancer. Pharmacogen 1995;4:333-40.
9. Kihara M, Noda K. Risk of smoking for squamous and small cell carcinomas of the lung modulated by combination of CYP1A1 and GSTM1 gene polymorphisms in a Japanese population. Carcinogenesis 1995;16:2331-36.
10. Ryberg D, Hewer A, Phillips DH, Haugen A. Different susceptibility to smoking-induced DNA damage among male and female lung cancer patients. Cancer Res 1994;54:5801-03.
11. Rojas M, Alexandrov K, Cascorbi I, Brockmöller J, Likhachev A, Pozharisski K, et al. High benzo(a)pyrene diol-epoxide DNA adduct levels in lung and blood cells from individuals with combined CYP1A1 MspI/MspI-GSTM1*0/*0 genotypes. Pharmacogen 1998;8:109-18.
12. Ryberg D, Skaug V, Hewer A, Phillips DH, Harries LW, Wolf CR, et al. Genotypes of glutathione transferase Ml and PI and their significance for lung DNA adduct levels and cancer risk. Carcinogenesis 1997;18:1285-89.
13. Mollerup S, Ryberg D, Hewer A, Phillips DH, Haugen A. Sex differences in lung CYP1A1 expression and DNA adduct levels among lung cancer patients. Cancer Res 1999;59:3317-20.
14. Kaiser J. Environment institute lays plans for gene hunt. Science 1997;278:569-70.
15. DeRisi J, Penland L, Brown PO, Bittner ML, Meltzer PS, Ray M, et al. Use of cDNA microassay to analyse gene expression patterns in human cancer. Nat Genet 1996;14:457-60.
16. Heller RA, Schena M, Chai A, Shalon D, Bedilion T, Gilmore J, et al. Discovery and analysis of inflammatory disease-related genes using cDNA microarrays. Proc Natl Acad Sci USA 1997;94:2150-55.
17. Brown PO, Botstein D. Exploring the new world of the genome with DNA arrays. Nat Genet 1999;21 suppl:33-7.
18. Nuwaysir EF, Bittner M, Trent J, Barret JC, Afshari CA. Microarrays and toxicology: the advent of toxicogenomics. Mol Carcinog 1999;24:153-9.
19. Halushka MK, Fan JB, Bentley K, Hsie L, Shen N, Weder A, et al. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat Genet 1999;22:239-47.
20. Cargill M, Altshuler D, Ireland J, Sklar P, Ardlie K, Paul N, et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 1999;22:231-38.