Inhibitory effect of oral administration of Lactobacillus casei on 3-methylcholanthrene-induced carcinogenesis in mice

Medical Microbiology and Immunology

Volumn 188, Issue 3, 1999, Pages 111-116

  Takagi, Akimitsu ^a   Matsuzaki, Takeshi ^a   Sato, Mikiko ^a   Nomoto, Koji ^a   Morotomi, Masami ^a   Yokokura, Teruo ^a  

^a YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

Author keywords

3 Methylcholanthrene; Cancer prevention; Chemically induced tumor; Lactobacillus casei; Oral administration

Indexed keywords

3 METHYLCHOLANTHRENE; CONCANAVALIN A; INTERLEUKIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARCINOGENESIS; CELL CULTURE; CONTROLLED STUDY; DIETARY INTAKE; IMMUNE RESPONSE; LACTOBACILLUS CASEI; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; TIME;

ANIMALS; BODY WEIGHT; DIET; LACTOBACILLUS CASEI; LYMPHOCYTE SUBSETS; MALE; METHYLCHOLANTHRENE; MICE; MICE, INBRED C3H; NEOPLASMS; SPLEEN;

EID: 0033378485     PISSN: 03008584     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004300050112     Document Type: Article

References (45)

1. 1. Morse MA, Stoner GD (1993) Cancer chemoprevention: principles and prospects. Carcinogenesis 14:1737-1746
2. 2. Rogers AE, Zeisel SH, Groopman J (1993) Diet and carcinogenesis. Carcinogenesis 14:2205-2217
3. 3. Goldin BR, Gorbach SL (1980) Effect of Lactobacillus acidophilus dietary supplements on 1,2-dimethylhydrazine dihydrochloride-induced intestinal cancer in rats. J Natl Cancer Inst 64:263-265
4. 4. Goldin BR, Gualtieri LJ, Moore RP (1996) The effect of Lactobacillus GG on the initiation and promotion of DMH-induced intestinal tumors in the rat. Nutr Cancer 25:197-204
5. 5. Rowland IR, Rumney CJ, Coutts JT, Lievense LC (1998) Effect of Bifidobacterium longum and inulin on gut bacterial metabolism and carcinogen-induced aberrant crypt foci in rats. Carcinogenesis 19:281-285
6. 6. Shign J, Rivenson A, Tomita M, Shimamura S, Ishibashi N, Reddy BS (1997) Bifidobacterium longum, a lactic acid-producing intestinal bacterium inhibits colon cancer and modulates the intermediate biomarkers of colon carcinogenesis. Carcinogenesis 18:833-841
7. 7. Challa A, Rao DR, Chawan CB, Shackelford L (1997) Bifidobacterium longum and lactulose suppress azoxymethane-induced colonic aberrant crypt foci in rats. Carcinogenesis 18:517-521
8. 8. Goldin B, Gorbach SL (1977) Alterations in fecal microflora enzymes related to diet, age, Lactobacillus supplements, and dimethylhydrazine. Cancer 40:2421-2426
9. 9. Goldin BR, Swenson L, Dwyer J, Sexton M, Gorbach SL (1980) Effect of diet and Lactobacillus acidophilus supplements on human fecal bacterial enzymes. J Natl Cancer Inst 64:255-261
10. 10. Rafter JJ (1995) The role of lactic acid bacteria in colon cancer prevention. Scand J Gastroenterol 30:497-502
11. y mice. Endocrine J 44:357-365
12. 12. Matsuzaki T, Nagata Y, Kado S, Uchida K, Kato I, Hashimoto S, Yokokura T (1997) Prevention of onset in an insulin-dependent diabetes mellitus model, NOD mice, by oral feeding of Lactobacillus casei. APMIS 105:643-649
13. 13. Matsuzaki T, Nagata Y, Kado S, Uchida K, Hashimoto S, Yokokura T (1997) Effect of oral adiministration of Lactobacillus casei on alloxan-induced diabetes in mice. APMIS 105:637-642
14. 14. Matsuzaki T, Yamazaki R, Hashimoto S, Yokokura T (1998) The effect of oral feeding of Lactobacillus casei strain Shirota on immunoglobulin E production in mice. J Dairy Sci 81:48-53
15. 15. Matsuzaki T, Yokokura T, Mutai M (1988) Antitumor effect of intrapleural administration of Lactobacillus casei in mice. Cancer Immunol Immunother 26:209-214
16. 16. Noguchi Y, Jungbluth A, Richards EC, Old LJ (1996) Effect of interleukin 12 on tumor induction by 3-methylcholanthrene. Proc Natl Acad Sci USA 93:11798-11801
17. 17. Konno A, Hishinuma K, Hashimoto Y, Kimura S, Nishimura T (1991) Dietary restriction reduces the incidence of 3-methylcholanthrene-induced tumors in mice: close correlation with its potentiating effect on host T cell functions. Cancer Immunol Immunother 33:293-298
18. 18. Halevy O, Rodel J, Peled A, Oren M (1991) Frequent p53 mutations in chemically induced murine fibrosarcoma. Oncogene 6:1593-1600
19. 19. Shimokado K, Watanabe H, Sumii M, Miyagawa K, Kamiya K, Dohi K, Niwa O (1998) p53 gene mutaion and loss of heterozygosity of chromosome 11 in methylcholanthrene-induced mouse sarcomas. Jpn J Cancer Res 89:269-277
20. 20. Watanabe H, Shimokado K, Asahara T, Dohi K, Niwa O (1999) Analysis of the c-myc, K-ras and p53 genes in methylcholanthrene-induced mouse sarcomas. Jpn J Cancer Res 90:40-47
21. 21. Makino H, Ushijima T, Kakiuchi H, Onda M, Ito N, Sugimura T, Nagao M (1994) Absence of p53 mutations in rat colon tumors induced by 2-amino-6-methyldipyrido[1,2-a:3′,2′-d]-imidazole, 2-amino-3-methylimidazo[4,5-f]quinoline, or 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Jpn J Cancer Res 85:510-514
22. 22. Weghorst CM, Dragnev KH, Buzard GS, Thorne KL, Vandeborne GF, Vincent KA, Rice JM (1994) Low incidence of point mutations detected in the p53 tumor suppressor gene from chemically induced rat renal mesenchymal tumors. Cancer Res 54:215-219
23. 23. Okamoto M, Ohtsu H, Kominami R, Yoneyama H (1995) Mutational and LOH analyses of p53 alleles in colon tumors induced by 1,2-dimethylhidrazine in F1 hybrid mice. Carcinogenesis 16:2659-2666
24. 24. Kito K, Kihara T, Sugita A, Muraso S, Akehi S, Sato M, Tachibana M, Kimura S, Ueda N (1996) Incidence of p53 and H-ras gene mutations in chemically induced rat mammary carcinomas. Mol Carcinog 17:78-83
25. 25. Hegi ME, Söderkvist P, Foley JF, Schoonhoven R, Swenberg JA, Kari F, Maronpot R, Anderson MW, Wiseman RW (1993) Characterization of p53 mutaions in methylene chloride-induced lung tumors from B6C3F1 mice. Carcinogenesis 14:803-810
26. 26. Makino H, Ishizaka Y, Tujimoto A, Nakamura T, Onda M, Sugimura T, Nagao M (1992) Rat p53 gene mutations in primary Zymbal gland tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline, a food mutagen. Proc Natl Acad Sci USA 89:4850-4854
27. 27. Fujii T, Igarashi T, Kishimoto S (1987) Significance of suppressor macrophages for immunosurveillance of tumor-bearing mice. J Natl Cancer Inst 78:509-517
28. 28. Dye ES, North RJ (1981) T cell-mediated immunosuppression as an obstacle to adoptive immunotherapy of the P815 mastocytoma and its metastases. J Exp Med 154:1033-1042
29. 29. Tamerius J, Nepom J, Hellström I, Hellström KE (1976) Tumor-associated blocking factors: isolation from sera of tumor-bearing mice. J Immunol 116:724-730
30. 30. Fujimoto S, Greene MI, Sehon AH (1976) Regulation of the immune response to tumor antigens I. Immunosuppressor cells in tumor-bearing hosts. J Immunol 116:791-799
31. 31. Treves AJ, Carnaud C, Trainin N, Feldman M, Cohen IR (1974) Enhancing T lymphocytes from tumor-bearing mice suppress host resistance to a syngeneic tumor. Eur J Immunol 4:722-727
32. 32. Kirchner H, Chused TM, Herberman RB, Holden HT, Lavrin DH (1974) Evidence of suppressor cell activity in spleens of mice bearing primary tumors induced by Moloney sarcoma virus. J Exp Med 139:1473-1487
33. 33. Fujiwara H, Hamaoka T, Nishino Y, Kitagawa M (1977) Inhibitory effect of tumor-bearing state on the generation of in vivo protective immune T cells in a syngeneic murine tumor system. Gann 68:589-601
34. 34. Takeichi N, Ba D, Koga Y, Kobayashi H (1983) Immunologic suppression of carcinogenesis in spontaneously hypertensive rats (SHR) with T cell depression. J Immunol 130:501-505
35. 35. Nelson M, Nelson DS (1988) Inhibition of cell-mediated immunity by tumour cell products: depression of interleukin-2 production and responses to interleukin-2 by mouse spleen cells. Immunol Cell Biol 66:97-104
36. 36. Smith KA (1984) Interleukin 2. Annu Rev Immunol 2:319-333
37. 37. Farrar WL, Johnson HM, Farrar JJ (1981) Regulation of the production of immune interferon and cytotoxic T lymphocytes by interleukin 2. J Immunol 126:1120-1125
38. 38. Handa K, Suzuki R, Matsui H, Shimizu Y, Kumagai K (1983) Natural killer (NK) cells as a responder to interleukin 2 (IL 2) II. IL 2-induced Interferon γ production. J Immunol 130:988-992
39. 39. Ghosh P, Komschlies KL, Cippitelli M, Longo DL, Subleski J, Ye J, Sica A, Young HA, Wiltrout RH, Ochoa AC (1995) Gradual loss of T-helper 1 populations in spleen of mice during progressive tumor growth. J Natl Cancer Inst 87:1478-1483
40. + T cell clones secrete the Th1 pattern of cytokines. J Immunol 144:1744-1752
41. + T cells secreting Th1 or Th2 cytokines. Immunity 2:271-279
42. 42. Shida K, Makino K, Morishita A, Takamizawa K, Hachimura S, Ametani A, Sato T, Kumagai Y, Habu S, Kaminogawa S (1998) Lactobacillus casei inhibits antigen-induced IgE secretion through regulation of cytokine production in murine splenocyte cultures. Int Arch Allergy Immunol 115:278-287
43. 43. Takahashi M, Iwata S, Yamazaki N, Fujiwara H (1991) Phagocytosis of the lactic acid bacteria by M cells in the rabbit Peyer's patches. J Clin Electron Microsc 24:5-6
44. 44. Kato I, Tanaka K, Yokokura T (1999) Lactic acid bacterium potently induces the production of interleukin-12 and interferon-γ by mouse splenocytes. Int J Immunopharmacol 21:121-131
45. 45. Brandtzaeg P, Halstensen TS, Kett K, Krajči P, Kvale D, Rognum TO, Scott H, Sollid LM (1989) Immunobiology and immunopathology of human gut mucosa: humoral immunity and intraepithelial lymphocytes. Gastroenterology 97:1562-1584