p53 gene mutation and loss of heterozygosity of chromosome 11 in methylcholanthrene-induced mouse sarcomas

Japanese Journal of Cancer Research

Volumn 89, Issue 3, 1998, Pages 269-277

  Shimokado, Kiyoshi ^a   Watanabe, Hiroshi ^a   Sumii, Masaharu ^b   Miyagawa, Kiyoshi ^b   Kamiya, Kenji ^b   Dohi, Kiyohiko ^a   Niwa, Ohtsura ^c  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

LOH; MCA; Mouse sarcoma; P53

Indexed keywords

3 METHYLCHOLANTHRENE; PROTEIN P53;

ALLELE; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CHROMOSOME 11; EXON; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; MISSENSE MUTATION; MOUSE; NONHUMAN; NONSENSE MUTATION; NUCLEIC ACID BASE SUBSTITUTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SARCOMA; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

EID: 0031969255     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1998.tb00558.x     Document Type: Article

References (42)

1. Hollstein, M., Sidransky, D., Vogelstein, B. and Harris, C. C. p53 mutations in human cancers. Science, 253, 49-53 (1991).
2. Levine, A. J., Momand, J. and Finlay, C. A. The p53 tumour suppressor gene. Nature, 351, 453-456 (1991).
3. Kuerbitz, S. J., Plunkett, B. S., Walsh, W. V. and Kastan, M. B. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA, 89, 7491-7495 (1992).
4. Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A. and Jacks, T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature, 362, 847-849 (1993).
5. Greenblatt, M. S., Bennett, W. P., Hollstein, M. and Harris, C. C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54, 4855-4878 (1994).
6. Soussi, T. and May, P. Structural aspects of the p53 protein in relation to gene evolution: a second look. J. Mol. Biol., 260, 623-637 (1996).
7. Makino, H., Ishizaka, Y., Tsujimoto, A., Nakamura, T., Onda, M., Sugimura, T. and Nagao, M. Rat p53 gene mutations in primary Zymbal gland tumors induced by 2-amino-3-methylimidazo [4,5-f]quinoline, a food mutagen. Proc. Natl. Acad. Sci. USA, 89, 4850-4854 (1992).
8. Makino, H., Ushijima, T., Kakiuchi, H., Onda, M., Ito, N., Sugimura, T. and Nagao, M. Absence of p53 mutations in rat colon tumors induced by 2-amino-6-inethyldipyrido-[1,2-a:3′,2′-d]imidazole, 2-amino-3-methylimidazo [4,5-f]-quinoline, or 2-amino-1-methyl-6-phenylimidazo [4,5-b]-pyridine. Jpn. J. Cancer Res., 85, 510-514 (1994).
9. Lazono, J. C., Nakazawa, H., Cros, M. P., Cabral, R. and Yamasaki, H. G→A mutations in p53 and Ha-ras genes in esophageal pupillomas induced by N-nitrosomethylbenzyl-amine in two strains of rats. Mol. Carcinog., 9, 33-39 (1994).
10. Kito, K., Kihara, T., Sugita, A., Murao, S., Akehi, S., Sato, M., Tachibana, M., Kimura, S. and Ueda, N. Incidence of p53 and H-ras gene mutations in chemically induced rat mammary carcinomas. Mol. Carcinog., 17, 78-83 (1996).
11. Masui, T., Dong, Y., Yamamoto, S., Takada, N., Nakanishi, H., Fukushima, S. and Tatematsu, M. p53 mutations in transitional cell carcinomas of the urinary bladder in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosoamine. Cancer Lett., 105, 105-112 (1996).
12. Matsumoto, K., Iwase, T., Hirono, I., Nishida, Y., Iwahori, Y., Hori, T., Asamoto, M., Takasuka, N., Kim, D. J., Ushijima, T., Nagao, M. and Tsuda, H. Demonstration of ras and p53 gene mutations in carcinomas in the forestomach and intestine and soft tissue sarcomas induced by N-methyl-N-nitrosourea in the rat. Jpn. J. Cancer Res., 88, 129-136 (1997).
13. 1 hybrid mice. Carcinogenesis, 16, 2659-2666 (1995).
14. Wang, D., Weghorst, C. M., Calvert, R. J. and Stoner, G. D. Mutations in the p53 tumor suppressor gene in rat esophageal papillomas induced by N-nitrosomethylbenzyl-amine. Carcinogenesis, 17, 625-630 (1996).
15. Hegi, M. E., Söderkvist, P., Foley, J. F., Schoonhoven, R., Swenberg, J. A., Kari, F., Maronpot, R., Anderson, M. W. and Wiseman, R. W. Characterization of p53 mutations in methylene chloride-induced lung tumors from B6C3F1 mice. Carcinogenesis, 14, 803-810 (1993).
16. Ruggeri, B., DiRado, M., Zhang, S. Y., Bauer, B., Goodrow, T. and Klein-Szanto, A. J. P. Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene. Proc. Natl. Acad. Sci. USA, 90, 1013-1017 (1993).
17. Weghorst, C. M., Dragnev, K. H., Buzard, G. S., Thorne, K. L., Vandeborne, G. F., Vincent, K. A. and Rice, J. M. Low incidence of point mutations detected in the p53 tumor suppressor gene from chemically induced rat renal mesenchymal tumors. Cancer Res., 54, 215-219 (1994).
18. Furihata, C., Tatematsu, M., Saito, M., Ishida, S., Nakanishi, H., Inada, K., Tei, H., Hattori, M., Ito, T. and Sakaki, Y. Rare occurrence of ras and p53 gene mutations in mouse stomach tumors induced by N-methyl-N-nitrosourea. Jpn. J. Cancer Res., 88, 363-368 (1997).
19. Niwa, O. and Kominami, R. Lack of allelic preference in amplification and loss of the c-myc oncogene in methylcholanthrene-induced mouse sarcomas. Jpn. J. Cancer Res., 83, 1192-1197 (1992).
20. Edwards, R. J., Murray, B. P., Murray, S., Schulz, T., Neubert, D., Gant, T. W., Thorgeirsson, S. S., Boobis, A. R. and Davies, D. S. Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human. Carcinogenesis, 15, 829-836 (1994).
21. Quattrochi, L. C., Vu, T. and Tukey, R. H. The human CYP1A2 gene and induction by 3-methylcholanthrene. J. Biol. Chem., 269, 6949-6954 (1994).
22. Niwa, O., Enoki, Y., Sadamoto, S., Kamiya, K. and Yokoro, K. Random process of metastasis and generation of heterogeneity in a mouse sarcoma line. Jpn. J. Cancer Res., 84, 42-47 (1993).
23. Bienz, B., Zakut-Houri, R., Givol, D. and Oren, M. Analysis of the gene coding for the murine cellular tumour antigen p53. EMBO J., 3, 2179-2183 (1984).
24. Orita, M., Iwahara, H., Kanasawa, H., Hayashi, K. and Sekiya, T. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphism. Proc. Natl. Acad. Sci. USA, 86, 2766-2770 (1989).
25. Buchberg, A. M., Moskow, J. J., Buckwalter, M. S. and Camper, S. A. Mouse chromosome 11. Mamm. Genome, 1, 158-191 (1991).
26. Halevy, O., Rodel, J., Peled, A. and Oren, M. Frequent p53 mutations in chemically induced murine fibrosarcoma. Oncogene, 6, 1593-1600 (1991).
27. Hollstein, M., Shomer, B., Greenblatt, M., Soussi, T., Moving, E., Montesano, R. and Harris, C. C. Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation. Nucleic Acids Res., 24, 141-146 (1996).
28. Yang, J.-L., Chen, R.-H., Muher, V. M. and McCormick, J.-J. Kinds and location of mutations induced by (±)-7β, 8α-dihydroxy-9α, 10α-epoxy-7, 8, 9, 10-tetrahydrobenzo[a]-pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyl-transferase gene in diploid human fibroblasts. Carcinogenesis, 12, 71-75 (1991).
29. Béroud, C., Verdier, F. and Soussi, T. p53 gene mutation: software and database. Nucleic Acids Res., 24, 147-150 (1996).
30. Toguchida, J., Yamaguchi, T., Ritchie, B., Beauchamp, R. L., Dayton, S. H., Herrera, G. E., Yamamuro, T., Kotoura, Y., Sasaki, M. S., Little, J. B., Weichselbaum, R. R., Ishizaki, K. and Yandell, D. W. Mutation spectrum of the p53 gene in bone and soft tissue sarcomas. Cancer Res., 52, 6194-6199 (1992).
31. Donehor, L. A., Harvey, M., Slagle, B. L., MacArthur, M. J., Montgomery, C. A., Jr., Butel, J. S. and Bradley, A. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature, 356, 215-221 (1992).
32. Purdie, C. A., Harrison, D. J., Peter, A., Dobbie, L., White, S., Howie, S. E. M., Salter, D. M., Bird, C. C., Wyllie, A. H., Hooper, M. L. and Clarke, A. R. Tumor incidence, spectrum and ploidy in mice with a large deletion in the p53 gene. Oncogene, 9, 603-609 (1994).
33. Baker, S. J., Preisinger, A. C., Jessup, J. M., Paraskeva, C., Marcowitz, S., Willson, J. K. V., Hamilton, S. and Vogelstein, B. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res., 50, 7717-7722 (1990).
34. Wiseman, R. W., Cochran, C., Dietrich, W., Lander, E. S. and Söderkvist, P. Allelotyping of butadiene-induced lung and mammary adenocarcinomas of B6C3F1 mice: frequent losses of heterozygosity in regions homologous to human tumor-suppressor genes. Proc. Natl. Acad. Sci. USA, 91, 3759-3763 (1994).
35. Kemp, C. J., Fee, F. and Balmain, A. Allelotype analysis of mouse skin tumors using polymorphic microsatellites: sequential genetic alterations on chromosome 6, 7, and 11. Cancer Res., 53, 6022-6027 (1993).
36. Dudley, M. E., Sundberg, J. P. and Roopenian, D. C. Motif-primed polymerase chain reaction-based allelotype of sarcomas induced by 3-methylcholanthrene in interspecific hybrid mice. Oncogene, 11, 517-524 (1995).
37. Brachmann, R. K., Vidai, M. and Boeke, J. D. Dominant-negative p53 mutations selected in yeast hit cancer hot spots. Proc. Natl. Acad. Sci. USA, 93, 4091-4095 (1996).
38. Huff, V. and Saunders, G. F. Wilms tumor genes. Biochim. Biophys. Acta, 1155, 295-306 (1993).
39. Zhan, S., Shapiro, D. N. and Helman, L. J. Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma. J. Clin. Invest., 94, 445-448 (1994).
40. KIP2 defines a new imprinted domain on chromosome 11p but is not a tumor suppressor gene in Wilms tumor. Oncogene, 14, 1201-1206 (1997).
41. Nishimori, H., Ogawa, K. and Taeno, H. Frequent deletion in chromosome 4 and duplication of chromosome 15 in liver epithelial cells derived from long-term culture of C3H mouse hepatocytes. Int. J. Cancer, 59, 108-113 (1994).
42. 1 mice exhibit parentally-biased loss of heterozygosity at the Lei (liver cells immortalization) locus on chromosome 4. Oncogene, 11, 2281-2287 (1995).