Hypomethylation is necessary but not sufficient for V(D)J recombination within a transgenic substrate

Molecular Immunology

Volumn 36, Issue 17, 1999, Pages 1169-1173

  Engler, Peter ^a   Storb, Ursula ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

CpG methylation; Immunoglobulin gene rearrangement; Transgenic mice

Indexed keywords

DNA; IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; B LYMPHOCYTE; CPG ISLAND; DNA METHYLATION; ENHANCER REGION; GENE LOCUS; GENE REARRANGEMENT; GENETIC RECOMBINATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE;

ANIMALS; BASE SEQUENCE; CPG ISLANDS; DNA METHYLATION; DNA PRIMERS; ENHANCER ELEMENTS (GENETICS); GENE REARRANGEMENT, B-LYMPHOCYTE; GENE REARRANGEMENT, T-LYMPHOCYTE; GENES, IMMUNOGLOBULIN; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; RECOMBINATION, GENETIC;

EID: 0033368119     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(99)00124-8     Document Type: Article

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