Steroid hormones as biomarkers of endocrine disruption in wildlife

ASTM Special Technical Publication

Volumn , Issue 1364, 1999, Pages 254-270

  Guillette Jr , Louis J ^a   Rooney, Andrew A ^a   Crain, D Andrew ^b   Orlando, Edward F ^a  

^a University of Florida ^*  (United States)

^b MARYVILLE COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; ENZYMES; FISHERIES; HORMONES; MARINE BIOLOGY; TOXIC MATERIALS;

AROMATASE; TESTOSTERONE; XENOBIOTICS;

TOXICITY;

EID: 0033363198     PISSN: 10403094     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (64)

1. Arnold S., Robinson, M. K., Guillette, L. J., Jr., and McLachlan, J. A. 1996, "A yeast estrogen screen for examining the relative exposure of cells to natural and xeno estrogens," Environmental Health Perspectives, Vol. 104, pp. 544-548.
2. Babic-Gojmerac, T., Kniewald, Z., and Kniewald. J. 1989, "Testosterone metabolism in neuroendocrine organs in male rats under atrazine and dethylatrazine influence, Journal of Steroid Biochemistry. Vol. 33, pp. 141-146.
3. Bern, H. 1992, "The fragile fetus," In: Chemically-induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection, pp. 9-15. (T. Colborn and C. Clement, Eds.). Vol. XXI. Princeton Sci. Publ. Co., Inc., Princeton.
4. Borg, B. 1994, "Androgens in teleost fishes," Comparative Biochemistry and Physiology, Vol. 109C, pp. 219-245.
5. Colborn, T., vom Saal, F. S., and Soto, A. M. 1993, "Developmental effects of endocrine-disrupting chemicals in wildlife and humans," Environmental Health Perspectives, Vol. 101, pp. 378-384.
6. Crain, D. A. 1997, "Effects of endocrine-disrupting contaminants on reproduction in the American alligator, Alligator mississippiensis.," Ph.D. Dissertation, University of Florida.
7. Crain, D. A. and Guillette, L. J., Jr. 1997, "Endocrine-disrupting contaminants and reproduction in vertebrate wildlife," Reviews in Toxicology, Vol. 1, pp. 47-70.
8. Crain D. A., Guillette, L. J., Jr., Pickford, D. B., Percival, H. F., and Woodward A. R. 1998a, "Sex-steroid and thyroid hormone concentrations in juvenile alligators (Alligator mississippiensis) from contaminated and reference lakes in Florida," Environmental Toxicology and Chemistry, Vol. 17, pp. 446-452.
9. Crain, D. A., Guillette, L. J., Jr., Rooney., A. A., and Pickford, D. B. 1997, "Alteration in steroidogenesis in alligators (Alligator mississippiensis) exposed naturally and experimentally to environmental contaminants," Environmental Health Perspectives Vol. 105, pp. 528-533.
10. Crain, D. A., Noriega, N., Vonier, P. M., Arnold, S. F., McLachlan, J. A., and Guillette, L. J., Jr. 1998b, "Cellular bioavailability of natural hormones and environmental contaminants as a function of serum and cytosolic binding factors," Toxicology and Industrial Health, Vol. 14, pp. 261-273.
11. Cree, A., Cockrem, J. F., and Guillette, L. J., Jr. 1992, "Reproductive cycles of male and female tuatara, (Sphenodon punctatus), on Stephens Island, New Zealand," Journal of Zoology, Vol. 226, pp. 199-217.
12. Davis, W. P. and Bortone, S. A. 1992, "Effects of kraft mill effluent on the sexuality of fishes: An environmental early warning?," In: Chemically-induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection, pp. 113-127. (T. Colborn and C. Clement, Eds.). Vol. XXI. Princeton Sci. Publ. Co., Inc., Princeton.
13. de Pablo, F. and Scanes, C. G. 1993, Handbook of Endocrine Research Techniques, Academic Pr., San Diego.
14. Desbrow, C., Routledge, E., Sheehan, D., Waldock, M., and Sumpter, J. 1996, "The identification and assessment of oestrogenic substances in sewage treatment works effluents," Environment Agency - U.K., P2-i490/7.
15. Folmar, L. C., Denslow, N. D., Rao, V., Chow, M., Crain, D. A., Enblom, J., Marcino, J., and Guillette, L. J., Jr. 1996, "Vitellogenin induction and reduced serum testosterone concentrations in feral male carp (Cyprinus carpio) captured near a major metropolitan sewage treatment plant," Environmental Health Perspectives, Vol. 104, pp. 1096-1101.
16. Goodbred, S. L., Gilliom, R. J., Gross, T. S., Denslow, N. P., Bryant, W. L., and Schoeb, T. R. 1997, "Reconnaissance of 17β-estradiol, 11-ketotestosterone, vitellogenin and gonad histopathology in common carp of United States streams: Potential for contaminant-induced endocrine disruption," U.S. Geological Survey, Open-File Report OFR 96-627.
17. Gray, L. E., Jr., Monosson, E., and Kelce, W. R. 1996, "Emerging issues: the effects of endocrine disrupters on reproductive development," In: Interconnections between Human and Ecosystem Health, pp. 45-82. (R. T. DiGiulio and E. Monosson, Eds.). Chapman and Hall, London.
18. Gray, L. E. J., Ostby, J. M., and Marshall, R. 1993, "The fungicide vinclozolin inhibits morphological sex differentiation in the male rat.," Biology of Reproduction Suppl., Vol. 48, pp. 97.
19. Guillette, L. J., Jr. 1995, "Endocrine disrupting environmental contaminants and developmental abnormalities in embryos," Human and Ecological Risk Assessment, Vol. 1, pp. 25-36.
20. Guillette, L. J., Jr., Arnold, S. F., and McLachlan, J. A. 1996a, "Ecoestrogens and Embryos - Is there a scientific basis for concern?," Animal Reproduction Science, Vol. 42, pp. 13-24.
21. Guillette, L. J., Jr., Brock, J. W., Rooney, A. A., and Woodward, A. R. 1999a, "Serum concentrations of various environmental contaminants and their relationship to sex steroid concentrations in the American alligator," Archives of Environmental Contamination and Toxicology, accepted.
22. Guillette, L. J., Jr., Crain, D. A., Rooney, A. A., and Pickford, D. B. 1995a, "Organization versus activation: The role of endocrine-disrupting contaminants (EDCs) during embryonic development in wildlife," Environmental Health Perspectives, Vol. 103 (Suppl. 7), pp. 157-164.
23. Guillette, L. J., Jr., Crain, D. A., Rooney, A. A., and Woodward, A. R. 1997a, "Effect of acute stress on plasma testosterone, estradiol- 17β and corticosterone concentrations in juvenile alligators living in control and contaminated lakes," Journal of Herpetology, Vol. 31, pp. 347-353.
24. Guillette, L. J., Jr., Gross, T. S., Gross, D., Rooney, A. A., and Percival, H. F. 1995b, "Gonadal steroidogenesis in vitro from juvenile alligators obtained from contaminated and control lakes," Environmental Health Perspectives, Vol. 103, Supplement 4, pp. 31-36.
25. Guillette, L. J., Jr., Gross, T. S., Masson, G. R., Matter, J. M., Percival, H. F., and Woodward, A. R. 1994, "Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida," Environmental Health Perspectives, Vol. 102, pp. 680-688.
26. Guillette, L. J., Jr., Pickford, D. B., Crain, D. A., Rooney, A. A., and Percival, H. F. 1996b, "Reduction in penis size and plasma testosterone concentrations in juvenile alligators living in a contaminated environment," General and Comparative Endocrinology, Vol. 101, pp. 32-42.
27. Guillette, L. J., Jr., Woodward, A. R., Crain, A. D., Masson, G. R., Palmer, B. D., Cox, M. G., Qui, Y.-X., and Orlando., E. F. 1997b, "The reproductive cycle of the female American alligator (Alligator mississippiensis)," General and Comparative Endocrinology, Vol. 108, pp. 87-101.
28. Guillette, L. J., Jr., Woodward, A. R., Crain, D. A., Pickford, D. B., Rooney, A. A., and Percival, H. F. 1999b, "Plasma steroid concentrations and male phallus size in juvenile alligators from seven Florida (USA) lakes," General and Comparative Endocrinology. accepted.
29. Harmon, M. A., Boehm, M. F., Heyman, R. A., and Mangelsdorf, D. J. 1995. "Activation of mammalian retinoid X receptors by the insect growth regulator methoprene," Proceeding of the National Academy of Science (USA), Vol. 92, pp. 6157-6160.
30. Hontela, A., Rasmussen, J. B., Audet, C., and Chevalier, G. 1992, "Impaired cortisol stress response in fish from environments polluted by PAHs, PCBs, and mercury," Archives of Environmental Contamination and Toxicology, Vol. 22, pp. 278-283.
31. Hose, J. H. and Guillette, L. J., Jr. 1995. "Defining the role of pollutants in the disruption of reproduction in wildlife," Environmental Health Perspectives, Vol. 103, Supplement 4, pp. 87-92.
32. Jobling, S., Reynolds, T., White, R., Parker, M. G., and Sumpter, J. P. 1995, "A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic," Environmental Health Perspectives, Vol. 103, pp. 582-587.
33. Jobling, S., Sheahan, D., Osborne, J. A., Matthiessen, P., and Sumpter, J. P. 1996, Inhibition of testicular growth in rainbow trout (Oncorhynchus mykiss) exposed to estrogenic alkylphenolic chemicals," Environmental Toxicology and Chemistry, Vol. 15, pp. 194-202.
34. Kelce, W. R., Monosson, E., Gamcsik, M. P., Laws, S. C., and Gray, L. E. J. 1994, "Environmental hormone disruptors: Evidence that vinclozolin developmental toxicity is mediated by antiandrogenic metabolites," Toxicology and Applied Pharmacology, Vol. 126, pp. 276-285.
35. Kelce, W. R., Stone, C. R., Laws, S. C., Gray, L. E., Kemppainen, J. A., and Wilson, E. M. 1995, "Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist," Nature, Vol. 375, pp. 581-585.
36. Kniewald, J., Mildner, P., and Kniewald, Z. 1979, "Effects of s-triazine herbicides on hormone-receptor complex formation, 5α reductase and 3α-hydroxysteroid dehydrogenase activity at the anterior pituitary level," Journal of Steroid Biochemistry, Vol. 11, pp. 833-838.
37. Kniewald, J., Peruzovic, M., Gojmerac, T., Milkovic, K., and Kniewald, Z. 1987, "Indirect influence of s-triazines on rat gonadotropic mechanism at early postnatal period," Journal of Steroid Biochemistry, Vol. 27, pp. 1095-1100.
38. Lang, J. W. and Andrews, H. V. 1994, "Temperature-dependent sex determination in crocodilians," Journal of Experimental Zoology, Vol. 270, pp. 28-44.
39. Licht, P., Frank, L. G., Pavgi, S., Yalcinkaya, T. M., Siiteri, P. K., and Glickman, S. E. 1992, "Hormonal correlates of 'masculinization' in female spotted hyaenas (Crocuta crocuta). 2. Maternal and fetal steroids," Journal of Reproduction and Fertility, Vol. 95, pp. 463-474.
40. Lye, C. M., Frid, C. L. J., Gill, M. E., and McCormick, D. 1997, "Abnormalities in the reproductive health of flounder Platichthys flesus exposed to effluent from a sewage treatment works," Marine Pollution Bulletin, Vol. 34, pp. 34-41.
41. MacLatchy, D. L. and Van Der Kraak, G. J. 1995, "The phytoestrogen β-sitosterol alters the reproductive endocrine status of goldfish," Toxicology and Applied Pharmacology, Vol. 134, pp. 305-312.
42. Masson, G. R. 1995, "Environmental influences on reproductive potential, clutch viability and embryonic mortality of the American alligator in Florida," Ph.D. Dissertation, University of Florida.
43. McLachlan, J. A. 1993, "Functional toxicology: A new approach to detect biologically active xenobiotics," Environmental Health Perspectives, Vol. 101, pp. 386-387.
44. McLachlan, J. A. and Arnold, S. F. 1996, "Environmental estrogens," American Scientist, Vol. 84, pp. 452-461.
45. McLachlan, J. A., Newbold, R. R., Teng, C. T., and Korach, K. S. 1992, "Environmental estrogens: orphan receptors and genetic imprinting," In: Chemically-induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection, pp. 107-112. (T. Colborn and C. Clement, Eds.). Vol. XXI. Princeton Sci. Publ. Co. Inc., Princeton.
46. McMaster, M. E., Van Der Kraak, G. J., Portt, C. B., Munkittrick, K. R., Sibley, P. K., Smith, I. R., and Dixon, D. G. 1991, "Changes in hepatic mixed function oxygenase (MFO) activity plasma steroid levels and age at maturity of a white sucker (Catastomus commersoni) population exposed to bleached kraft pulp mill effluent," Aquatic Toxicology, Vol. 21, pp. 199-218.
47. McMaster, M. E., Munkittrick, K. R., Van Der Kraak, G. J., Flett, P. L., and Servos, M. R. 1996, "Detection of steroid hormone disruptions associated with pulp mill effluent using artificial exposures of goldfish," In: Environmental Fate and Effects of Pulp and Paper Mill Effluents, pp. 425-437. (M. R. Servos, K. R. Munkittrick, J. H. Carey, and G. J. Van Der Kraak, Eds.). St. Lucie Press, Delray Beach, FL.
48. McMaster, M. E., Munkittrick, K. R., Luxon, P. L., and Van Der Kraak, G. J. 1994, "Impact of low-level sampling stress on interpretation of physiological responses of white sucker exposed to effluent from a bleached kraft pulp mill," Ecotoxicology and Environmetal Safety, Vol. 27, pp. 251-264.
49. Munkittrick, K. R., Portt, C. B., Van Der Kraak, G. J., Smith, I. R., and Rokosh, D. A. 1991, "Impact of bleached kraft mill effluent on population characteristics, liver MFO activity and serum steroids of the Lake Superior white sucker (Catostomus commersoni) population," Canadian Journal of Fisheries and Aquatic Science, Vol. 48, pp. 1-10.
50. Munkittrick K. R., Van Der Kraak, G. J., McMaster, M. E., Portt, C. B., van den Heuvel, M. R., and Servos, M. R. 1994, "Survey of receiving-water environmental impacts associated with discharges from pulp mills. 2. Gonad size, live size, hepatic EROD activity and plasma sex steroid levels in white sucker," Environmental Toxicology and Chemistry, Vol. 13, pp. 1089-1101.
51. Nagel, S. C., vom Saal, F. S., Thayer, K. A., Dhar, M. G., Boechler, M., and Welshons, W. V. 1997, "Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens Bisphenol A and octylphenol," Environmental Health Perspectives, Vol. 105, pp. 70-76.
52. National Research Council. 1991, Animals as sentinels of environmental health hazards, National Academy Pr., Washington, D.C.
53. Norris, D. O. 1997, Vertebrate Endocrinology, Academic Press, San Diego.
54. Orlando, E. F., Denslow, N., Folmar, L., and Guillette, L. J., Jr. 1999, "Comparison of the reproductive physiology of Largemouth bass, Micropterus salmoides, collected from the Escambia and Blackwater Rivers in Florida," Environmental Health Perspectives, in press.
55. Peterson, R. E., Theobald, H. M., and Kimmel, G. L. 1993, "Developmental and reproductive toxicology of dioxins and related compounds: cross-species comparisons," Critical Reviews in Toxicology, Vol. 23, pp. 283-335.
56. Pickford, D. B. 1995, "Endocrine regulation of clitero-penis development in the juvenile American alligator (Alligator mississippiensis)," M.S., University of Florida.
57. Schelske, C. and Brezonik, P. 1992, "Can Lake Apopka be restored?," In: Restoration of Aquatic Ecosystems: Science, Technology and Public Policy, pp. 393-398. National Academy of Sciences, Washington, DC.
58. Selye, H. 1973, "The evolution of the stress concept," American Scientist, Vol. 61, pp. 692-699.
59. Soto, A. M., Sonnenschein, C., Chung, K. L., Fernandez, M. F., Olea, N., and Olea Serrano, F. 1995, "The E-SCREEN assay as a tool to identify estrogens: An update on estrogenic environmental pollutants," Environmental Health Perspectives, Vol. 103 (Suppl. 7), pp. 113-122.
60. Toppari, J., Larsen, J. C., Christiansen, P., Giwercman, A., Grandjean, P., Guillette, L. J., Jr., Jegou, B., Jensen, T. K., Jouannet, P., Keiding, N., Leffers, H., McLachlan, , J. A., Meyer, O., Muller, J., Rajpert-De Meyts, E., Scheike, T., Sharpe, R., Sumpter, J., and Skakkebaek, N. E. 1996, "Male reproductive health and environmental xenoestrogens," Environmental Health Perspectives, Vol. 104 (Suppl. 4), pp. 741-803.
61. Van Der Kraak, G. J., Munkittrick, K. R., McMaster, M. E., Portt, C. B., and Chang, J. P. 1992, "Exposure to bleached kraft pulp mill effluent disrupts the pituitary-gonadal axis of white sucker at multiple sites," Toxicology and Applied Pharmacology, Vol. 115, pp. 224-233.
62. vom Saal, F. S., Nagel, S. C., Palanza, P., Boechler, M., Parmigiani, S., and Welshons, W. V. 1995, "Estrogenic pesticides: binding relative to estradiol in MCF-7 cells and effects of exposure during fetal life on subsequent territorial behavior in male mice," Toxicology Letters, Vol. 77, pp. 343-350.
63. Vonier, P. M., Crain, D. A., McLachlan, J. A., Guillette, L. J., Jr., and Arnold, S. F. 1996, "Interaction of environmental chemicals with the estrogen and progesterone receptors from the oviduct of the American alligator," Environmental Health Perspectives, Vol. 104, pp. 1318-1322.
64. Woodward, A. R., Jennings, M. L., Percival, H. F., and Moore, C. T. 1993, "Low clutch viability of American alligators on Lake Apopka," Florida Scientist, Vol. 56, pp. 52-63.