Endothelin-mediated vascular growth requires p42/p44 mitogen-activated protein kinase and p70 S6 kinase cascades via transactivation of epidermal growth factor receptor

Endocrinology

Volumn 140, Issue 10, 1999, Pages 4659-4668

  Iwasaki, H ^a   Eguchi, S ^a   Ueno, H ^a   Marumo, F ^a   Hirata, Y ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN; ENDOTHELIN 1; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; S6 KINASE;

ANIMAL CELL; ARTICLE; CARDIOVASCULAR SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; GROWTH STIMULATION; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TRANSACTIVATION;

EID: 0033305744     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.10.7023     Document Type: Article

References (59)

1. Receptor protein-tyrosine kinases and their signal transduction pathways
2. Regulation of signal transduction and signal diversity by receptor oligomerization
3. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
4. Activation of mitogen-activated protein kinases (ERK/JNK) and AP-I transcription factor in rat carotid arteries after ballon injury
5. Cell replication in the arterial wall: Activation of signaling pathway following in vivo injury
6. Mitogenic signaling via G protein-coupled receptors
7. A signal pathway to translational control
8. The molecular phosphorylation and activation of p70(S6K)
9. PDGF- and insulin-dependent pp70(S6K) activation mediated by phosphatidylinusitol-3-OH kinase
10. Activation of p70/p85 S6 kinase by a pathway independent of p21(ras)
11. Role of p70 S6 kinase in angiotensin II-induced protein synthesis in vascular smooth, muscle cells
12. Activation of p70 S6 kinase is necessary for angiotensin II-induced hypertrophy in neonatal rat cardiac myocytes
13. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
14. Endothelins: Homeostatic and compensatory actions in the circulatory and endocine systems
15. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells
16. Endothelin is a potent mitogen for rat vascular smooth muscle cells
17. A novel ETA receptor antagonist (BQ-123) inhibits endothelin-l-induced phosphoinositide breakdown and DNA synthesis in rat vascular smooth muscle cells
18. Endothelln action on vascular smooth muscle involves inositol triphosphate and calcium mobilization
19. Endothelin rapidly stimulates mitogen-activated protein kinase activity in rat mesangial cells
20. Endothelins stimulate tyrosine phosphorylation and activity of p42/mitogen-activated protein kinase in astrocytes
21. Role of transactivation of the EGF receptor in signaling by G-protein-coupled receptors
22. Adrenomedullin as a novel growth-promoting factor for cultured vascular smooth muscle cells: Role of tyrosine kinase-mediated mitogen-activated protein kinase activation
23. Adenovirus-mediated transfer of a dominant-negative H-ras suppresses neointimal formation in balloon-injured arteries in vivo
24. Tyrosine kinase inhibition: An approach to drug development
25. Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation
26. PD98059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
27. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
28. Circulating and tissue endothelin immunoreactivity in hypercholesterolemic pigs
29. Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis
30. Tissue endothelin-1 immunoreactivity in the active coronary atherosclerotic plaque
31. Increased trnmunoreactive endothelin-1 in human transplant coronary artery disease
32. Endothelin-converting enzyme expression in the rat vascular injury model and human coronary artherosclerosis
33. Expression of endothelin-J, endothelin-3, endothelin-converting enzyme-1, and endothelin-A and endothelin-B receptor mRNA after angioplasty-induced neointimal formation in the rat
34. Increased endothelin-1 content in blood vessels of deoxycorticosterone acetate-salt hypertensive but not in spontaneously hypertensive rats
35. A role for endogenous endothelin-1 in neointimal formation after rat carotid artery balloon angioplasty: Protective effects of the novel nonpeptide endothelin receptor antagonist SB 209670
36. Nonselective ETA/ETB receptor antagonist blocks proliferation of rat vascular smooth muscle cells after balloon angioplasty
37. Effect of a nonselective endothelin antagonist on vascular remodeling in deoxycorticosterone acetate-salt hypertensive rats
38. Endothelin, vasopressin, and angiotensin II enhance tyrosine phosphorylation by protein kinase C-dependent and -independent pathways in glomerular mesangial cells
39. Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells
40. Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells
41. The ml muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity
42. Involvement of PYK2 in angiotensin II signaling of vascular smooth muscle cells
43. Biphasic activation of p21(ras) by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase
44. Endothelin-1-induced mitogenic responses of Chinese hamster ovary ceils expressing human endothelin A: The role of a wartmannin-sensitive signaling pathway
45. Cellular stresses differentially activate c-Jun N-terminal protein kinases and extracellular signalregulated protein kinases in cultured ventrlcular myocytes
46. Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: A role in cardiac myocyte hypertrophy?
47. Neu and its ligands: From an oncogene to neural factors
48. Protein kinase C and protein tyrosine kinase activity contribute to mitogenic signaling by endothelin-1: Cross-talk between G protein-coupled receptors and pp60(c-src)
49. The heterotrimeric Gq protein-coupled angiotensin II receptor activates p21(ras) via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes
50. Activation of extracellular signal-regulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells
51. Endothelin induces tyrosine phosphorylation and GRB2 association of Shc in astrocytes
52. Gβγ, subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor
53. Signal characteristics of G protein-transactivated EGF receptor
54. Critical role of calcium-dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling
55. Angiotensin II stimulates ERK via two pathways in epithelial cells: Protein kinase C suppresses a G-protein coupled-EGF receptor transactivation pathway
56. Nuclear signaling by endothelin-1
57. Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059
58. PHAS/4E-BPs as regulators of mRNA translation and cell proliferation
59. Activation of the ras mitogen-activated protein kinase-ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gene transcription by insulin