메뉴 건너뛰기




Volumn 12, Issue 6, 1999, Pages 420-428

Insulin regulation of protein metabolism in vivo

Author keywords

mRNA translation; Proteasome; Protein synthesis; Proteolysis; Ubiquitin

Indexed keywords

INSULIN; MUSCLE PROTEIN; PROTEIN; ADENOSINE TRIPHOSPHATE; AMINO ACID; CARBOHYDRATE; FATTY ACID; GLUCOSE; GLYCOGEN; TRIACYLGLYCEROL;

EID: 0033291523     PISSN: 03943402     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (46)
  • 1
    • 0021917182 scopus 로고
    • The ATP dependence of the degradation of short- And long-lived proteins in growing fibroblasts
    • Gronostajski R.M., Pardee A.B., Goldberg A.L.: The ATP dependence of the degradation of short- and long-lived proteins in growing fibroblasts. J. Biol. Chem. 260: 3344-3349, 1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 3344-3349
    • Gronostajski, R.M.1    Pardee, A.B.2    Goldberg, A.L.3
  • 2
    • 0032520870 scopus 로고    scopus 로고
    • Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans
    • Petersen K.F., Laurent D., Rothman D.L., Cline G.W., Shulman G.I.: Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans. J. Clin. Invest. 101: 1203-1209, 1998.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1203-1209
    • Petersen, K.F.1    Laurent, D.2    Rothman, D.L.3    Cline, G.W.4    Shulman, G.I.5
  • 3
    • 0027142443 scopus 로고
    • Insulin and glucose suppress hepatic glycogenolysis by distinct enzymatic mechanisms
    • Liu Z., Gardner L.B., Barrett E.J.: Insulin and glucose suppress hepatic glycogenolysis by distinct enzymatic mechanisms. Metabolism 42: 1546-1551, 1993.
    • (1993) Metabolism , vol.42 , pp. 1546-1551
    • Liu, Z.1    Gardner, L.B.2    Barrett, E.J.3
  • 4
    • 0025007289 scopus 로고
    • Dose-dependent effect of insulin on plasma free fatty acid turnover and oxidation in humans
    • Bonadonna R.C., Groop L.C., Zych K., Shank M., DeFronzo R.A.: Dose-dependent effect of insulin on plasma free fatty acid turnover and oxidation in humans. Am. J. Physiol. 259: E736-E750, 1990.
    • (1990) Am. J. Physiol. , vol.259
    • Bonadonna, R.C.1    Groop, L.C.2    Zych, K.3    Shank, M.4    Defronzo, R.A.5
  • 5
    • 0022338995 scopus 로고
    • Insulin-mediated reduction of whole body protein breakdown - Dose-response effects on leucine metabolism in postabsorptive man
    • Fukagawa N.K., Minaker K.L., Rowe J.W., Goodman M.N., Matthews D.E., Bier D.M., Young V.R.: Insulin-mediated reduction of whole body protein breakdown - Dose-response effects on leucine metabolism in postabsorptive man. J. Clin. Invest. 76: 2306-2311, 1985.
    • (1985) J. Clin. Invest. , vol.76 , pp. 2306-2311
    • Fukagawa, N.K.1    Minaker, K.L.2    Rowe, J.W.3    Goodman, M.N.4    Matthews, D.E.5    Bier, D.M.6    Young, V.R.7
  • 7
    • 0015217652 scopus 로고
    • Regulation of protein synthesis in heart muscle II - Effect of amino acid levels and insulin on ribosomal aggregation
    • Morgan H.E., Jefferson L.S., Wolpert E.B., Rannels D.E.: Regulation of protein synthesis in heart muscle II - Effect of amino acid levels and insulin on ribosomal aggregation. J. Biol. Chem. 246: 2163-2170, 1971.
    • (1971) J. Biol. Chem. , vol.246 , pp. 2163-2170
    • Morgan, H.E.1    Jefferson, L.S.2    Wolpert, E.B.3    Rannels, D.E.4
  • 8
    • 0015326908 scopus 로고
    • Effect of insulin on protein synthesis in skeletal muscle of an isolated perfused preparation of rat hemicorpus
    • Jefferson L.S., Koehler J.O., Morgan H.E.: Effect of insulin on protein synthesis in skeletal muscle of an isolated perfused preparation of rat hemicorpus. Proc. Natl. Acad. Sci. USA 69: 816-820, 1972.
    • (1972) Proc. Natl. Acad. Sci. USA , vol.69 , pp. 816-820
    • Jefferson, L.S.1    Koehler, J.O.2    Morgan, H.E.3
  • 9
    • 0019022878 scopus 로고
    • Role of insulin in the regulation of protein synthesis
    • Jefferson L.S.: Role of insulin in the regulation of protein synthesis. Diabetes 29: 487-496, 1980.
    • (1980) Diabetes , vol.29 , pp. 487-496
    • Jefferson, L.S.1
  • 10
    • 0023511486 scopus 로고
    • Effect of insulin and plasma amino acid concentrations on leucine metabolism in man
    • Castellino P., Luzi L., Simonson D.C., Haymond M., DeFronzo R.A.: Effect of insulin and plasma amino acid concentrations on leucine metabolism in man. J. Clin. Invest. 80: 1784-1793, 1987.
    • (1987) J. Clin. Invest. , vol.80 , pp. 1784-1793
    • Castellino, P.1    Luzi, L.2    Simonson, D.C.3    Haymond, M.4    DeFronzo, R.A.5
  • 11
    • 0023377246 scopus 로고
    • An isotopic method for in vivo measurement of muscle protein synthesis and degradation
    • Barrett E.J., Revkin J.H., Young L.H., Zaret B.L., Jacob R., Gelfand R.A.: An isotopic method for in vivo measurement of muscle protein synthesis and degradation. Biochem. J. 245: 223-228, 1987.
    • (1987) Biochem. J. , vol.245 , pp. 223-228
    • Barrett, E.J.1    Revkin, J.H.2    Young, L.H.3    Zaret, B.L.4    Jacob, R.5    Gelfand, R.A.6
  • 12
    • 0026316130 scopus 로고
    • Proteolysis in skeletal muscle and whole body in response to euglycemic hyperinsulinemia in normal adults
    • Denne S.C., Liechty E.A., Liu Y.M., Brechtel G., Baron A.D.: Proteolysis in skeletal muscle and whole body in response to euglycemic hyperinsulinemia in normal adults. Am. J. Physiol. 261: E809-E814, 1991.
    • (1991) Am. J. Physiol. , vol.261
    • Denne, S.C.1    Liechty, E.A.2    Liu, Y.M.3    Brechtel, G.4    Baron, A.D.5
  • 13
    • 0024503822 scopus 로고
    • Failure of insulin infusion to stimulate fractional muscle protein synthesis in type I diabetic patients
    • Pacy P.J., Nair K.S., Ford C., Halliday D.: Failure of insulin infusion to stimulate fractional muscle protein synthesis in type I diabetic patients. Diabetes 38: 618-624, 1989.
    • (1989) Diabetes , vol.38 , pp. 618-624
    • Pacy, P.J.1    Nair, K.S.2    Ford, C.3    Halliday, D.4
  • 14
    • 0019214262 scopus 로고
    • A rapid and convenient technique for measuring the rate of protein synthesis in tissues by injection of [3H]phenylalanine
    • Garlick P.J., McNurlan M.A., Preedy V.R.: A rapid and convenient technique for measuring the rate of protein synthesis in tissues by injection of [3H]phenylalanine. Biochem. J. 192: 719-723, 1980.
    • (1980) Biochem. J. , vol.192 , pp. 719-723
    • Garlick, P.J.1    McNurlan, M.A.2    Preedy, V.R.3
  • 15
    • 0027288716 scopus 로고
    • Response of rat heart and skeletal muscle protein in vivo to insulin and amino acid infusion
    • McNulty P.M., Young L.H., Barrett E.J.: Response of rat heart and skeletal muscle protein in vivo to insulin and amino acid infusion. Am. J. Physiol. 264: E958-E965, 1993.
    • (1993) Am. J. Physiol. , vol.264
    • McNulty, P.M.1    Young, L.H.2    Barrett, E.J.3
  • 16
    • 0026522047 scopus 로고
    • Attenuated responses of muscle protein synthesis to fasting and insulin in adult female rats
    • Baillie A.G.S., Garlick P.J.: Attenuated responses of muscle protein synthesis to fasting and insulin in adult female rats. Am. J. Physiol. 262: E1-E5, 1992.
    • (1992) Am. J. Physiol. , vol.262
    • Baillie, A.G.S.1    Garlick, P.J.2
  • 18
    • 0023723070 scopus 로고
    • Amino acid infusion increases the sensitivity of muscle protein synthesis in vivo to insulin
    • Garlick P.J., Grant I.: Amino acid infusion increases the sensitivity of muscle protein synthesis in vivo to insulin. Biochem. J. 254: 579-584, 1988.
    • (1988) Biochem. J. , vol.254 , pp. 579-584
    • Garlick, P.J.1    Grant, I.2
  • 19
    • 0030766238 scopus 로고    scopus 로고
    • Insulin-stimulated amino acid utilization during glucose and amino acid clamps decreases with development
    • Wraycahen D., Beckett P.R., Nguyen H.V., Davis T.A.: Insulin-stimulated amino acid utilization during glucose and amino acid clamps decreases with development. Am. J. Physiol. 36: E305-E314, 1997.
    • (1997) Am. J. Physiol. , vol.36
    • Wraycahen, D.1    Beckett, P.R.2    Nguyen, H.V.3    Davis, T.A.4
  • 20
    • 0029788084 scopus 로고    scopus 로고
    • Insulin stimulation of protein synthesis in rat skeletal muscle following resistance exercise is maintained with advancing age
    • Fluckey J.D., Vary T.C., Jefferson L.S., Evans W.J., Farrell P.: Insulin stimulation of protein synthesis in rat skeletal muscle following resistance exercise is maintained with advancing age. J. Gerontol. S. 51: B323-B330, 1996.
    • (1996) J. Gerontol. S. , vol.51
    • Fluckey, J.D.1    Vary, T.C.2    Jefferson, L.S.3    Evans, W.J.4    Farrell, P.5
  • 21
    • 0028219050 scopus 로고
    • Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats
    • Dardevet D., Sornet C., Attaix D., Baracos V.E., Grizard J.: Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats. Endocrinology 134: 1475-1484, 1994.
    • (1994) Endocrinology , vol.134 , pp. 1475-1484
    • Dardevet, D.1    Sornet, C.2    Attaix, D.3    Baracos, V.E.4    Grizard, J.5
  • 22
    • 0028008197 scopus 로고
    • Effect of insulin on rat heart and skeletal muscle phenylalanyl-tRNA labeling and protein synthesis in vivo
    • Young L.H., Stirewalt W., McNulty P.H., Revkin J.H., Barrett E.J.: Effect of insulin on rat heart and skeletal muscle phenylalanyl-tRNA labeling and protein synthesis in vivo. Am. J. Physiol. 267: E337-E342, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • Young, L.H.1    Stirewalt, W.2    McNulty, P.H.3    Revkin, J.H.4    Barrett, E.J.5
  • 23
    • 4243311389 scopus 로고    scopus 로고
    • Does insulin stimulate muscle protein synthesis in humans
    • Albright R., Joyner M., Dietz N., Nair K.S.: Does insulin stimulate muscle protein synthesis in humans. Diabetes 48 (Suppl. 1): A69, 1999.
    • (1999) Diabetes , vol.48 , Issue.1 SUPPL.
    • Albright, R.1    Joyner, M.2    Dietz, N.3    Nair, K.S.4
  • 24
    • 0027228038 scopus 로고
    • Anabolic effects of insulin like growth factor 1 (IGF-1) and IGF-1 variant in normal female rats
    • Tomas F.M., Knowles S.E., Chandler C.S., Francis G.L., Owens P.C., Ballard F.J.: Anabolic effects of insulin like growth factor 1 (IGF-1) and IGF-1 variant in normal female rats. J. Endocrinol. 137: 413-421, 1993.
    • (1993) J. Endocrinol. , vol.137 , pp. 413-421
    • Tomas, F.M.1    Knowles, S.E.2    Chandler, C.S.3    Francis, G.L.4    Owens, P.C.5    Ballard, F.J.6
  • 25
    • 13344268999 scopus 로고    scopus 로고
    • IGF-I stimulation of muscle protein synthesis in the awake rat: Permissive role of insulin and amino acids
    • Jacob R., Hu X., Niederstock D., Hasan S., McNulty P.H., Sherwin R.S., Young L.H.: IGF-I stimulation of muscle protein synthesis in the awake rat: permissive role of insulin and amino acids. Am. J. Physiol. 270: E60-E66, 1996.
    • (1996) Am. J. Physiol. , vol.270
    • Jacob, R.1    Hu, X.2    Niederstock, D.3    Hasan, S.4    McNulty, P.H.5    Sherwin, R.S.6    Young, L.H.7
  • 26
    • 0028128530 scopus 로고
    • Insulin-like growth factor I exerts growth hormone- And insulin-like actions on human muscle protein metabolism
    • Fryburg D.A.: Insulin-like growth factor I exerts growth hormone- and insulin-like actions on human muscle protein metabolism. Am. J. Physiol. 267: E331-E336, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • Fryburg, D.A.1
  • 27
    • 0031804253 scopus 로고    scopus 로고
    • Extreme hyperinsulinemia unmasks insulin's effect to stimulate protein synthesis in the human forearm
    • Hillier T., Fryburg D., Jahn L., Barrett E.: Extreme hyperinsulinemia unmasks insulin's effect to stimulate protein synthesis in the human forearm. Am. J. Physiol. 274: E1067-E1074, 1998.
    • (1998) Am. J. Physiol. , vol.274
    • Hillier, T.1    Fryburg, D.2    Jahn, L.3    Barrett, E.4
  • 28
    • 0029418405 scopus 로고
    • Regulation of p70s6k/p85s6k and its role in the cell cycle
    • Pearson R.B., Thomas G.: Regulation of p70s6k/p85s6k and its role in the cell cycle. Progress Cell Cycle Res. 1: 21-32, 1995.
    • (1995) Progress Cell Cycle Res. , vol.1 , pp. 21-32
    • Pearson, R.B.1    Thomas, G.2
  • 29
    • 0030883848 scopus 로고    scopus 로고
    • PHAS/4E-BPS as regulators of MRNA translation and cell proliferation
    • Lawrence J.C., Abraham R.T.: PHAS/4E-BPS as regulators of MRNA translation and cell proliferation [Review]. Trends Biochem. Sci. 22: 345-349, 1997.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 345-349
    • Lawrence, J.C.1    Abraham, R.T.2
  • 30
    • 0030901124 scopus 로고    scopus 로고
    • Insulin stimulates protein synthesis in muscle by enhancing the association of eif-4e and eif-4g
    • Kimball S.R., Jurasinski C.V., Lawrence J.C., Jefferson L.S.: Insulin stimulates protein synthesis in muscle by enhancing the association of eif-4e and eif-4g. Am. J. Physiol. 41: C754-C759, 1997.
    • (1997) Am. J. Physiol. , vol.41
    • Kimball, S.R.1    Jurasinski, C.V.2    Lawrence, J.C.3    Jefferson, L.S.4
  • 31
    • 0032528917 scopus 로고    scopus 로고
    • Amino acid availability regulates p70 S6 kinase and multiple translation factors
    • Wang X., Campbell L.E., Miller C.M., Proud C.G.: Amino acid availability regulates p70 S6 kinase and multiple translation factors. Biochem. J. 334: 261-267, 1998.
    • (1998) Biochem. J. , vol.334 , pp. 261-267
    • Wang, X.1    Campbell, L.E.2    Miller, C.M.3    Proud, C.G.4
  • 32
    • 0032486268 scopus 로고    scopus 로고
    • Amino acid sufficiency and Mtor regulate P70 S6 kinase and Eif-4e Bp1 through a common effector mechanism
    • Hara K., Yonezawa K., Weng Q.P., Kozlowski M.T., Belham C., Avruch J.: Amino acid sufficiency and Mtor regulate P70 S6 kinase and Eif-4e Bp1 through a common effector mechanism. J. Biol. Chem. 273: 14484-14494, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14484-14494
    • Hara, K.1    Yonezawa, K.2    Weng, Q.P.3    Kozlowski, M.T.4    Belham, C.5    Avruch, J.6
  • 33
    • 0030593939 scopus 로고    scopus 로고
    • Mechanisms of muscle wasting
    • Mitch W., Goldberg A.L.: Mechanisms of muscle wasting. N. Engl. J. Med. 335: 1897-1905, 1996.
    • (1996) N. Engl. J. Med. , vol.335 , pp. 1897-1905
    • Mitch, W.1    Goldberg, A.L.2
  • 34
    • 0029956781 scopus 로고    scopus 로고
    • Importance of the ATP-ubiquitin-proteasome pathway inthe degradation of soluble and myofibrillar proteins in rabbit muscle extracts
    • Solomon V., Goldberg A.: Importance of the ATP-ubiquitin-proteasome pathway inthe degradation of soluble and myofibrillar proteins in rabbit muscle extracts. J. Biol. Chem. 271: 26690-26697, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 26690-26697
    • Solomon, V.1    Goldberg, A.2
  • 35
    • 0029861468 scopus 로고    scopus 로고
    • Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome proteolytic pathway by a mechanism including gene transcription
    • Price S.R., Bailey J.L., Wang X., Jurkovitz C., England B.K., Ding X., Philips L.S., Mitch W.E.: Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome proteolytic pathway by a mechanism including gene transcription. J. Clin. Invest. 98: 1703-1708, 1996.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1703-1708
    • Price, S.R.1    Bailey, J.L.2    Wang, X.3    Jurkovitz, C.4    England, B.K.5    Ding, X.6    Philips, L.S.7    Mitch, W.E.8
  • 36
    • 0029000181 scopus 로고
    • Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy
    • Medina R., Wing S.S., Goldberg A.L.: Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy. Biochem J. 307: 631-637, 1995.
    • (1995) Biochem J. , vol.307 , pp. 631-637
    • Medina, R.1    Wing, S.S.2    Goldberg, A.L.3
  • 37
    • 0032454767 scopus 로고    scopus 로고
    • Effects of thyroid hormones on myofibrillar proteolysis and activities of calpain, proteasome, and cathepsin in primary cultured chick muscle cells
    • Nakashima K., Ohtsuka A., Hayashi K.: Effects of thyroid hormones on myofibrillar proteolysis and activities of calpain, proteasome, and cathepsin in primary cultured chick muscle cells. J. Nutr. Sci. Vitaminol. 44: 799-807, 1998.
    • (1998) J. Nutr. Sci. Vitaminol. , vol.44 , pp. 799-807
    • Nakashima, K.1    Ohtsuka, A.2    Hayashi, K.3
  • 38
    • 0010862043 scopus 로고
    • Skeletal muscle proteasome can degrade proteins in an ATP-dependent process that does not require ubiquitin
    • Driscoll J., Goldberg A.L.: Skeletal muscle proteasome can degrade proteins in an ATP-dependent process that does not require ubiquitin. Proc. Natl. Acad. Sci. USA 86: 787-791, 1989.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 787-791
    • Driscoll, J.1    Goldberg, A.L.2
  • 39
    • 0030016595 scopus 로고    scopus 로고
    • Structure and function of the 20S and 26S proteasomes
    • Coux O., Tanaka K., Goldberg A.L.: Structure and function of the 20S and 26S proteasomes. Ann. Rev. Biochem. 65: 801-826, 1996.
    • (1996) Ann. Rev. Biochem. , vol.65 , pp. 801-826
    • Coux, O.1    Tanaka, K.2    Goldberg, A.L.3
  • 40
    • 0029945963 scopus 로고    scopus 로고
    • Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo
    • May R.C., Bailey J.L., Mitch W.E., Masud T., England B.K.: Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo. Kidney Int. 49: 679-83, 1996.
    • (1996) Kidney Int. , vol.49 , pp. 679-683
    • May, R.C.1    Bailey, J.L.2    Mitch, W.E.3    Masud, T.4    England, B.K.5
  • 42
    • 0029040739 scopus 로고
    • Activation of the ATP-ubiquitin-proteasome pathway in skeletal muscle of cachectic rats bearing a hepatoma
    • Baracos V.E., DeVivo C., Hoyle D.H.R., Goldberg A.L.: Activation of the ATP-ubiquitin-proteasome pathway in skeletal muscle of cachectic rats bearing a hepatoma. Am. J. Physiol. 268: E996-E1006, 1995.
    • (1995) Am. J. Physiol. , vol.268
    • Baracos, V.E.1    DeVivo, C.2    Hoyle, D.H.R.3    Goldberg, A.L.4
  • 43
    • 0029022262 scopus 로고
    • Increase in ubiquitin-protein conjugates concomitant with the increase in proteolysis in rat skeletal muscle during starvation and atrophy denervation
    • Wing S.S., Haas A.L., Goldberg A.L.: Increase in ubiquitin-protein conjugates concomitant with the increase in proteolysis in rat skeletal muscle during starvation and atrophy denervation. Biochem. J. 307: 639-645, 1995.
    • (1995) Biochem. J. , vol.307 , pp. 639-645
    • Wing, S.S.1    Haas, A.L.2    Goldberg, A.L.3
  • 44
    • 0028817382 scopus 로고
    • Burn injury stimulates multiple proteolytic pathways in skeletal muscle, including the ubiquitin-energy-dependent pathway
    • Fang C.H., Tiao G., James H., Ogle C., Fischer J.E., Hasselgren P.O.: Burn injury stimulates multiple proteolytic pathways in skeletal muscle, including the ubiquitin-energy-dependent pathway. J. Am. Coll. Surg. 180: 161-170, 1995.
    • (1995) J. Am. Coll. Surg. , vol.180 , pp. 161-170
    • Fang, C.H.1    Tiao, G.2    James, H.3    Ogle, C.4    Fischer, J.E.5    Hasselgren, P.O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.