Pathophysiology of the oxidative stress and its implication in uremia and dialysis

Contributions to Nephrology

Volumn 127, Issue , 1999, Pages 1-31

  Galli, Francesco ^a   Canestrari, Franco ^a   Bellomo, Giorgio ^b  

^a UNIVERSITY OF URBINO   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ANTIOXIDANT; FREE RADICAL;

CELL DIVISION; CHRONIC KIDNEY FAILURE; HUMAN; LIPID METABOLISM; METABOLISM; OXIDATIVE STRESS; RENAL REPLACEMENT THERAPY; REVIEW; UREMIA;

ANTIOXIDANTS; CELL DIVISION; FREE RADICALS; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; KIDNEY FAILURE, CHRONIC; LIPID METABOLISM; OXIDATIVE STRESS; RENAL DIALYSIS; UREMIA;

EID: 0033253716     PISSN: 03025144     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000060009     Document Type: Article

References (103)

1. Sies H: Oxidative Stress. II. Oxidantsand Antioxidants. London, Academic Press, 1991.
2. Suzuki YJ, Forman HJ, Sevanian A: Oxidants as stimulator of signal transduction. Free Radie Biol Med 1997;22:269-285.
3. Rice-Evans CA, Diplock AT: Current status of antioxidant therapy. Free Radie Biol Med 1993;15: 77-96.
4. Halliwell B, Gutteridge JMC: Free Radicals in Biology and Medicine, ed 3. Oxford, Oxford University Press, 1999.
5. Bellomo G, Orrenius S: Altered thiol and calcium homeostasis in oxidative hepatocellular injury. Hepatology 1985;5:876-882.
6. Seen CK, Packer L: Antioxidants and redox regulation of gene transcription. FASEB J 1996;10: 709-720.
7. Dypbukt JM, Ankarcrona M, Burkitt M, Sjoholm A, Strom K, Orrenius S, Nicotera P: Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. J Biol Chem 1994;269:30553-30560.
8. Diplock AT, Chaleux JL, Crozier-Willi G, Kok FS, Rice-Evans C, Roberfroid M, Stahl W, Wina-Ribes J: Functional food sciences and defenses against reactive oxygen species. Br J Nutr 1998;80: S77-S112.
9. Packer L: Nitric oxide. A. Sources and detection of NO; NO synthase. Method Enzymol 1996;268: 331-340.
10. Rice-Evans CA, Gopinathan V: Oxygen toxicity, free radicals and antioxidants in human disease: Biochemical implications in atherosclerosis and the problems of premature neonates; in Apps DK, Tripton KF: Essays in Biochemistry. London, Portland Press, 1995, pp 39-63.
11. Moore K, Roberts LJ: Measurement of lipid peroxidation. Free Radie Res 1998;28:659-671.
12. Redanna P, Whelan J, Burgess JR, Eskew ML, Hildenbrandt G, Zarkower A, Scholz RW, Reddy CC: The role of vitamin E and selenium on arachidonic acid oxidation by way of the 5-lipoxygenase pathway. Ann NY Acad Sci 1989;570:136-145.
13. Zeng L, Xia Y, Garcia GE, Hwang D, Wilson CB: Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide. J Clin Invest 1995;95:1669-1675.
14. Sun Y, Oberley LW: Redox regulation of transcriptional activators. Free Radie Biol Med 1996;21: 335-348.
15. Martin E, Bhakdi S: Flow cytometry assay for quantifying opsonophagocytosis and killing of Staphylococcus aureus by peripheral blood leukocytes. J Clin Microbiol 1992;30:2246-2255.
16. Miesel R, Hartung R, Kroeger H: Priming of NADPH oxidase by tumor necrosis factor-alpha in patients with inflammatory and autoimmune rheumatic diseases. Inflammation 1996;20:427-438.
17. Rothe G, Valet G: Flow cytometry assay of oxidative burst activity in phagocytes. Methods Enzymol 1994;233:539-548.
18. Hogg N, Darley-Usmar VM, Wilson MT, Moncada S: The oxidation of α-tocopherol in human low-density lipoprotein by the simultaneous generation of Superoxide and nitric oxide. FEBS Lett 1993;326:199-203.
19. Beckman JS: Oxidative damage and tyrosine nitration from peroxynitrite. Chem Res Toxicol 1996; 9:836-844.
20. Szabo C, Ohshima H: DNA damage induced by peroxynitrite: Subsequent biological effects. Nitric Oxide Biol Chem 1997;1373-1385.
21. Ziouzencova O, Sevanian A, Abuja PM, Ramos P, Esterbauer H: Copper can promote oxidation of LDLby markedly different mechanisms. Free Radie Biol Med 1998;24:607-623.
22. Rosenmund R, Binswanger U, Straub PW: Oxidative injury to erythrocytes, cell rigidity and splenic hemolysis in hemodialyzed uremic patients. Ann Intern Med 1975;82:460-465.
23. Moore KP, Holt SG, Patel RP, Svistunenko DA, Zackert W, Goodier D, Reeder BJ, Clozel M, Anand R, Cooper CE, Morrow JD, Wilson MT, Darley-Usmar V, Roberts LJII: A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure. J Biol Chem, 1998;273:31731-31737.
24. Dubick MA, Hunter GC, Casey SM, Keen CL: Aortic ascorbic acid, trace elements, and Superoxide dismutase activity in human aneurysmal disease. Proc Soc Exp Biol Med 1987;184:138-143.
25. Smith C, Mitchinson MJ, Aruoma OI, Halliwell B. Stimulation of lipid peroxidation and hydroxylradical generation by the contents of human atherosclerotic lesions. Biochem J 1992;286:901-905.
26. Holt S, Reeder B, Wilson M, Harvey S, Morrow JD, Roberts LJ II, Moore K: Increased lipid peroxidation in patients with rhabdomyolysis. Lancet 1999;353:1241.
27. Galli F, Canestrari F, Buoncristiani U. Biological effects of oxidative stress in hemodialysis. Blood Purif 1999; 17:79-94.
28. Strain JJ, Mulholland CW: Vitamin C and vitamin E - Synergistic interactions in vivo?; in Emerit I, Chance B (eds): Free Radicals and Aging. Birkhäuser, Basel, 1992, pp 419-422.
29. Packer L: Interactions among antioxidants in health and disease: Vitamin E and its redox cycle. Proc Soc Exp Biol Med 1992;200:271-276.
30. Canestrari F, Galli F, Giorgini A, Galiotta P, Pascucci M, Bossu M: Erythrocyte redox state in uremic anemia: Effects of hemodialysis and relevance of glutathione metabolism. Acta Haematol 1994;91:187-193.
31. Galli F, Rovidati S, Ghibelli L, Canestrari F: S-nitrosylation of glyceraldehyde 3-phosphate dehydrogenase decreases the enzyme affinity to the erythrocyte membrane. Nitric Oxide 1998;2:17-27.
32. Bellomo G, Thor H, Eklow-Lastbom L, Nicotera P, Orrenius S: Oxidative stress: Mechanism of cytotoxicity. Chem Scripta 1987;27A:117-120.
33. Fernandes RS, Cotter TG: Apoptosis or necrosis: Intracellular levels of glutathione influence mode of cell death. Biochem Pharmacol 1994;48:675-681.
34. Galli F, Rovidati S, Buoncristiani U, Floridi A, Canestrari F: Erythrocyte glutathione S-transferase expression in the uremic syndrome. Clin Chem 1999;45:in press.
35. Van der Vliet A, Bast A: Effect of oxidative stress on receptor and signal transmission. Chem Biol Interact 1992;85:95-116.
36. Ghibelli L, Fanelli C, Rotilio G, Lafavia E, Coppola S, Colussi C, Civitareale P, Ciriolo MR: Rescue from apoptosis by inhibition of active GSH extrusion. FASEB J 1998;12:479-486.
37. Lennon SV, Martin SJ, Cotter TG: Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli. Cell Prolif 1991;24:203-214.
38. Dini L, Coppola S, Ruzittu MT, Ghibelli L: Multiple pathways for apoptotic nuclear fragmentation. Exp Cell Res 1996;223:340-347.
39. Hockenbery DM, Oltvai ZN, Yin XN, Milliman CL, Korsmeyer SJ: Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993;75:241-251.
40. Flohe L, Brigelius-Flohe R, Saliou C, Traber MG, Packer L: Redox regulation of NF-KB activation. Free Radie Biol Med 1997;22:1115-1126.
41. Esterbauer H, Shaur RJ, Zollner H: Chemistry and biochemistry of 4-hydroxynonenal, malonaldehydeand related aldehydes. Free Radie Biol Med 1991;11:81-128.
42. Rimm EB, Stampfer MJ, Ascherio A, Giovannucci E, Colditz GA, Willet WC: Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med 1993;328:1450-1456.
43. Chan AC: Vitamin E and atherosclerosis. J Nutr 1998;128:1593-1596.
44. Sandstrom PA, Roberts B, Folks TM, Butke TM: HIV gene expression enhances T cell susceptibility of hydrogen peroxide-induced apoptosis. AIDS Res Human Retroviruses 1993;9:1107-1113.
45. Bendich A: Antioxidant vitamins and human immune responses; in Litwack G (ed): Vitamins and Hormones. San Diego, Academic Press, 1996, pp 35-62.
46. Nath KA, Grande J, Croatt A, Haugen J, Kim Y, Rosenberg ME: Redox regulation of renal DNA synthesis, transforming growth factor-beta-1 and collagen gene expression. Kidney Int 1998;53:367-381.
47. Turi S, Nameth I, Torkos A, Saghy L, Varga I, Matkovics B, Nagy J: Oxidative stress and antioxidant defense mechanism in glomerular diseases. Free Radie Biol Med 1997;22:161-168.
48. Hasselwander O, Young IS: Oxidative stress in chronic renal failure. Free Radie Res 1998;29:1-11.
49. Huysmans K, Lins RL, Daelemans R, Zachée P, De Broe ME: Hypertension and accelerated atherosclerosis in end-stage renal disease. J Nephrol 1998;11:185-195.
50. Roselaar SE, Nazhat NB, Winyard PG, Jones P, Cunningham J, Blake DR: Detection of oxidants in uremic plasma by electron spin resonance spectroscopy. Kidney Int 1995;48:199-206.
51. Miyata T, van Ypersele de Sitrihou C, Kurokawa K, Baynes JW: Alterations in nonenzymatic biochemistry in uremia: Origin and significance of'carbonyl stress' in long-term uremic complications. Kidney Int 1999;55:389-399.
52. Himmelfarb J, Lazarus JM, Hakim R: Reactive oxygen species production by monocytes and polymorphonuclear leukocytes during dialysis. Am J Kidney Dis 1991;17:271-276.
53. Galli F, Rovidati S, Benedetti S, Canestrari F, Ferraro B, Floridi A, Buoncristiani U: Lipid peroxidation, leukocyte function and apoptosis in HD patients treated with vitamin E-modified filters. Contrib Nephrol. Basel, Karger, 1999, vol 127, pp 156-171.
54. Bonomini M, Sirolli V, Stuard S, Settefrati N: Interactions between platelets and leukocytes during hemodialysis. Artif Organs 1999;23:23-28.
55. Markert M, Wauters JP: New aspects on oxidative metabolism of neutrophils during hemodialysis on different dialyzer membranes; in Horl WH, Schollmeyer PJ (eds): New Aspects of Human Polymorphonuclear Leukocytes. New York, Plenum Press, 1991.
56. Buoncristiani U, Galli F, Benedetti S, Errico R, Beninati S, Ghibelli L, Rovidati S, Floridi A, Canestrari F: Quantitative and qualitative assessment and clinical meaning of molecules removed with BK membranes; in Ronco C (ed): PMMA, A Flexible Membrane for a Tailored Dialysis. Contrib Nephrol. Basel, Karger, 1998, vol 125, pp 133-158.
57. Galli F, Rovidati S, Chiarantini L, Kulurianu H, Canestrari F, Buoncristiani U: Bioreactivity and biocompatibility of a vitamin E-modified multi-layer hemodialysis filter. Kidney Int 1998;54:580-589.
58. Kose K, Dogan P, Gunduz Z, Dusunsel R, Utas C: Oxidative stress in hemodialysis patients and the long-term effects of dialyzer reuse practice. Clin Biochem 1997;30:601-606.
59. Epperlein MM, Nourooz-Zadeh J, Jayasena SD, Hothersall JS, Noronha-Dutra A, Neild GH: Nature and biological significance of free radicals generated during bicarbonate hemodialysis. J Am Soc Nephrol 1998;9:457-463.
60. Buoncristiani U, Galli F, Rovidati S, Albertini MC, Covarelli C, Carobi C, Di Paolo N, Canestrari F: Bicarbonate versus lactate buffer in peritoneal dialysis solutions: The benefical effect on RBC metabolism. Peril Dial Int 1996;16:511-518.
61. Vanholder R, De Smet R, Waterloos MA, Van Landschoot N, Vogeleere P, Hoste E, Ringoir S: Mechanisms of uremic inhibition of phagocyte-reactive species production: Characterization of the role of p-cresol. Kidney Int 1995;47:510-517.
62. Turi S, Nemeth I, Varga I, Bodrogi T, Matkovics B: The effect of erythropoietin on the cellular defence mechanism of red blood cells in children with chronic renal failure. Pediatr Nephrol 1992; 6:536-541.
63. Cristol JP, Bosc JY, Badiou S, Leblanc M, Lorrho R, Descomps B, Canaud B: Erythropoietin and oxidative stress in hemodialysis. Beneficial effects of vitamin E supplementation. Nephrol Dial Transplant 1997;12:2312-2317.
64. Peuchant E, Carbonneau MA, Dubourg L, Thomas MJ, Perromat A, Vallot C, Clerc M: Lipoperoxidation in plasma and red blood cells of patients undergoing haemodialysis: Vitamins A, E and iron status. Free Radic Biol Med 1994;16:339-346.
65. Caballos-Picot I, Witko-Sarsat V, Merad-Boudia M, Nguyen AT, Thevenin M, Jaudon MC, Zingraff J, Verger C, Jungers P, Descamps-Latscha B: Glutathione antioxidant system as a marker of oxidative stress in chronic renal failure. Free Radic Biol Med 1996;21:845-853.
66. Ono K: Effect of large dose vitamin E supplementation on anemia in hemodialysis patients. Nephron 1985;4:440-445.
67. Fiorillo C, Oliviero C, Rizzuti G, Nediani C, Pacini A, Nassi P: Oxidative stress and antioxidant defenses in renal patients receiving regular haemodialysis. Clin Chem Lab Med 1998;36:149-153.
68. Zima T, Janebova M, Nemecek K, Bartova V: Retinol and alpha-tocopherol in hemodialysis patients. Ren Fail 1998;20:505-512.
69. Martin-Mateo MC, del Canto-Jafiez E, Barrero-Martinez MJ: Oxidative stress and enzyme activity in ambulatorial renal patients undergoing continuous peritoneal dialysis. Ren Fail 1998;20:117-124.
70. Chen CK, Liaw JM, Juang JG, Lin TH: Antioxidant enzymes and trace elements in hemodialyzed patients. Biol Trace Elem Res 1997;58:149-157.
71. Canestrari F, Buoncristiani U, Galli F, Giorgini A, Albertini MC, Carobi C, Pascucci M, Bossu M: Redox state, antioxidative activity and lipid peroxidation in the erythrocytes and plasma of chronic ambulatorial peritoneal dialysis patients. Clin Chim Acta 1995;234:127-136.
72. Chauhan DP, Gupta PH, Nampoothiri MRN, Singal PC, Chugh KS, Nair CR: Determination of erythrocyte Superoxide dismutase, catalase, glucose-6-phosphate dehydrogenase, reduced glutathione and malonyldialdehyde in uremia. Clin Chim Acta 1982;123:153-159.
73. Durak I, Akyol O, Basesme E, Canbola O, Kavutcu M: Reduced erythrocyte defense mechanisms against free radical toxicity in patients with chronic renal failure. Nephron 1994;66:76-80.
74. Shurtz-Swirski R, Mashiach E, Kristal B, Shkolnik T, Shasha SM: Antioxidant enzymes activity in polymorphonuclear leukocytes in chronic renal failure. Nephron 1995;71:176-179.
75. Perna AF, Ingrosso D, Zappia V, Galletti P: Enzymatic methyl esterification of erythrocyte membrane proteins is impaired in chronic renal failure. J Clin Invest 1993;91:2497-2503.
76. Witko-Sarsat V, Friedlander M, Capeillere-Blandin C, Nguyen-Khoa T, Nguyen AT, Zingraff J, Jungers P, Descamps-Latscha B: Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int 1996;49:1304-1313.
77. Ross EA, Koo LC, Moberly JB: Low whole blood and erythrocyte levels of glutathione in hemodialysis and peritoneal dialysis patients. Am J Kidney Dis 1997;30:489-494.
78. Buoncristiani U, Galli F, Rovidati S, Albertini MC, Covarelli C, Canestrari F: Oxidative damage during hemodialysis using a vitamin E-modified dialysis membrane: A preliminary characterization. Nephron 1997;77:57-61.
79. Yawata Y, Jacobs HS: Abnormal red cell metabolism in patients with chronic uremia. Nature of the defect and its persistence despite adequate hemodialysis. Blood 1975;45:231-239.
80. Panzetta O, Cominacci L, Garbin U, Fratta Pasini A, Gammaro L, Bianco F, Davoli A, Campagnola M, De Sancis A, Pastorino AM: Increased susceptibility of LDL to in vitro oxidation in patients on maintenance hemodialysis: Effects of fish oil and vitamin E administration. Clin Nephrol 1995;44: 303-309.
81. McDonnel MG, Archbold GP: Plasma ubiquinol/cholesterol ratios in patients with hyperlipidaemia, those with diabetes mellitus and in patients requiring dialysis. Clin Chim Acta 1996;253:117-126.
82. Schiavon R, De Fanti E, Giavarina D, Biasioli S, Cavalcanti G, Guidi G: Serum paraoxonase activity is decreased in uremic patients. Clin Chim Acta 1996;247:71-80.
83. Dasgupta A, Hussain S, Ahmad S: Increased lipid peroxidation in patients on maintenance hemodialysis. Nephron 1992;60:56-59.
84. Ando M, Gafvels M, Bergstrom J, Lindholm B, Lundkvist I: Uremic serum enhances scavenger receptor expression and activity in the human monocytic cell line U937. Kidney Int 1997;51:785-792.
85. Wethuyzen J, Saltissi D, Healy H: Oxidation of low density lipoprotein in hemodialysis patients: Effect of dialysis and comparison with matched controls. Atherosclerosis 1997;129:199-205.
86. Lucchi L, Banni S, Botti B, Cappelli G, Medici G, Melis MP, Tomasi A, Vannini V, Lusvarghi E: Conjugated diene fatty acids in patients with chronic renal failure: Evidence of increased lipid peroxidation? Nephron 1993;65:401-409.
87. Sanaka T, Higuchi C, Shinobe T, Nishimura H, Omata M, Nihei H, Sugino N: Lipid peroxidation as an indicator of biocompatibility in haemodialysis. Nephrol Dial Transplant 1995;10:34-38.
88. Dasgupta A, Malhotra D, Levy H, Marcadis D, Blackwell W, Johnston D: Decreased total antioxidant capacity but normal lipid hydroperoxide concentrations in sera of critically ill patients. Life Sci 1997;60:335-340.
89. Miyata T, Fu MX, Kurokawa K, van Ypersele de Strihou C, Thorpe SR, Baynes JW: Autooxidation products of both carbohydrates and lipids are increased in uremic plasma: Is there oxidative stress in uremia? Kidney Int 1998;54:1290-1295.
90. Schettler V, Wieland E, Verwiebe R, Schuff-Werner P, Scheler F, Oellerich M: Plasma lipids are not oxidized during hemodialysis. Nephron 1994;67:42-47.
91. 2 cytotoxicity pH-dependent?; in Rice-Evans C, Halliwell B (eds): Free Radicals: Methodology and Concepts. London, Richelieu Press, 1988, pp 539-551.
92. Levey AS, Eknoyan G: Cardiovascular disease in chronic renal disease. Nephrol Dial Transplant 1999;14:828-833.
93. Hashimoto H, Mio T, Sumino K: Lipid abnormalities of erythrocyte membranes in hemodialysis patients with chronic renal failure. Clin Chim Acta 1996;252:137-145.
94. 2-microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implication for the pathogenesis of dialysis-related amyloidosis. J Clin Invest 1996;98:1088-1094.
95. Haklar G, Yegenaga I, Yalcin AS: Evaluation of oxidant stress in chronic hemodialysis patients: Use of different parameters. Clin Chim Acta 1995;234:109-114.
96. Odetti P, Garibaldi S, Gurreri G, Aragno I, Dapino D, Pronzato MA, Marinari UM: Protein oxidation in hemodialysis and kidney transplantation. Metabolism 1996;45:1319-1322.
97. Hassan MQ, Hussain SA, Zaki MA, Alsharif NZ, Stohs SJ: Protective effects of antioxidants against uraemia-induced lipid peroxidation and glutathione depletion in humans. Pharmacol Toxicol 1995;77:407-411.
98. Zachee P, Ferrant A, Daelemans R, Goossens W, Boogaerts MA, Lins RL: Reduced glutathione for the treatment of anemia during hemodialysis: A preliminary communication. Nephron 1995;71: 343-349.
99. Costagliola C, Romano L, Scibelli G, de Vincentiis A, Sorice P, Di Benedetto A: Anemia and chronic renal failure: A therapeutical approach by reduced glutathione parenteral administration. Nephron 1992;61:404-408.
100. Usberti M, Lima G, Arisi M, Bufano G, D'Avanzo L, Gazzotti RM: Effect of exogenous reduced glutathione on the survival of red blood cells in hemodialyzed patients. J Nephrol 1997;10:261-265.
101. Taccone-Gallucci M, Lubrano R, Clerico A, Meloni C, Morosetti M, Meschini L, Elli M, Trapasso E, Castello MA, Casciani CU: Administration of GSH has no influence on the RBC membrane: Oxidative damage to patients on hemodialysis. ASAIO J 1992;38:855-857.
102. Ricciarelli R, Tasinato A, Clement S, Ozer NK, Boscoboinik D, Azzi A: Alpha-tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state. Biochem J 1998;15:243-249.
103. Loughrey CM, Young IS, Lightbody JH, McMaster D, McNamee PT, Trimble ER: Oxidative stress in hemodialysis. Q J Med 1994;87:679-683.