Copper can promote oxidation of LDL by markedly different mechanisms

Free Radical Biology and Medicine

Volumn 24, Issue 4, 1998, Pages 607-623

  Ziouzenkova, Ouliana ^a   Sevanian, Alex ^a   Abuja, Peter M ^b   Ramos, Pilar ^b   Esterbauer, Hermann ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NONE

Author keywords

Antioxidants; Copper ion; Free radicals; Lipid peroxidation; Low density lipoprotein

Indexed keywords

ALKADIENE; ALPHA TOCOPHEROL; ANTIOXIDANT; CAROTENOID; CHOLESTEROL ESTER; COPPER; GAMMA TOCOPHEROL; HYDROPEROXIDE; LINOLEIC ACID ETHYL ESTER; LOW DENSITY LIPOPROTEIN;

ADULT; ARTICLE; CHEMICAL REACTION KINETICS; HUMAN; LIPID OXIDATION; LIPID PEROXIDATION; NORMAL HUMAN; PRIORITY JOURNAL; REACTION ANALYSIS;

ADULT; CAROTENOIDS; COPPER; FREE RADICALS; HUMANS; KINETICS; LIPID PEROXIDATION; LIPOPROTEINS, LDL; OXIDATION-REDUCTION; SPECTROPHOTOMETRY; VITAMIN E;

EID: 0032031115     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00324-9     Document Type: Article

References (43)

1. Esterbauer H., Gebicke J., Puhl H., Jürgens G. The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic. Biol. Med. 13:1992;341-390.
2. Esterbauer H., Jürgens G. Mechanistic and genetic aspects of susceptibility of LDL to oxidation. Curr. Opin. Lipidol. 4:1993;114-124.
3. Stocker R. Lipoprotein oxidation: Mechanistic aspects, methodological approaches and clinical relevance. Curr. Opin. Lipidol. 5:1994;422-433.
4. Esterbauer H., Ramos P. Chemistry and pathophysiology of oxidation of LDL. Rev. Physiol. Biochem. Pharmacol. 127:1995;31-64.
5. 2+ mediated oxidationof LDL. Bellomo G., Finardi G., Maggi E., Rice-Evans C. Free radicals, lipoprotein oxidation and atherosclerosis. 1995;11-26 Richelieu Press, London.
6. Ziouzenkova O., Gieseg S. P., Ramos P., Esterbauer H. Factors affecting resistance of low density lipoproteins to oxidation. Lipids. 31:1996;S71-S76.
7. Croft K. D., Williams P., Dimmitt S., Abu-Amsha R., Beilin L. J. Oxidation of low-density lipoproteins: Effect of antioxidant content, fatty acid composition and intrinsic phospholipase activity on susceptibility to metal-ion induced oxidation. Biochim. Biophys. Acta. 1254:1995;250-256.
8. Maiorino M., Zamburlini A., Roveri A., Ursini F. Copper-induced lipid peroxidation in liposomes, micelles, and LDL: Which is the role of vitamin E? Free Radic. Biol. Med. 18:1995;67-74.
9. Kontush A., Hübner Ch., Finckh B., Kohlschütter A., Beisiegel U. How different constituents of low density lipoprotein determine its oxidizability by copper: A correlational approach. Free Rad. Res. 24:1996;135-147.
10. Regnström J., Nilsson J., Tornvall P., Landau C., Hamsten A. Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man. Lancet. 339:1992;1183-1286.
11. Maggi E., Belazzi R., Falaschi F., Frattoni A., Perani G., Finardi G., Gazo A., Nai M., Romanini D., Bellomo G. Enhanced LDL oxidation in uremic patients: An additional mechanism for accelerated atherosclerosis? Kidney Int. 45:1994;876-883.
12. Stalenhoef A. F. H., Defesche J. C., Kleinveld H. A., Demacker P. N. M., Kastelein J. J. P. Decreased resistance against in vitro oxidation of LDL from patients with familial defective apolipoprotein B-100. Arterioscler. Thromb. 14:1994;489-493.
13. De Rijke Y. B., Verwey H. F., Vogelezang C. J. M., Van Der Velde E. A., Princen H. M. G., Van Der Laarse A., Bruschke A. V. G., Van Berkel T. J. C. Enhanced susceptibility of low-density lipoproteins to oxidation in coronary bypass patients with progression of atherosclerosis. Clin. Chim. Acta. 243:1995;127-149.
14. Porkkala-Sarataho E., Nyyssönen K., Salonen J. T. Increased oxidation resistance of atherogenic plasma lipoproteins at high vitamin E levels in non-vitamin E supplemented men. Atherosclerosis. 124:1996;83-94.
15. O'Leary V. J., Tilling L., Fleetwood G., Stone D., Darley-Usmar V. The resistance of low density lipoprotein to oxidation promoted by copper and its use as an index of antioxidant therapy. Atherosclerosis. 119:1996;169-179.
16. Beard Ch. M., Barnard R. J., Robbins D. C., Ordovas J. M., Schaefer E. J. Effects of diet and exercise on qualitative and quantitative measures of LDL and its susceptibility to oxidation. Arterioscler. Thromb. Vasc. Biol. 16:1996;201-207.
17. Kleinveld H. A., Hak-Lemmers H. L. M., Stalenhoef A. F. H., Demacker P. N. M. Improved measurement of low-density lipoprotein susceptibility to copper-induced oxidation: Application of a short procedure for isolating low-density lipoprotein. Clin. Chem. 38:1992;2066-2072.
18. Gieseg S. P., Esterbauer H. Low-density lipoprotein is saturable by prooxidant copper. FEBS Lett. 343:1994;188-194.
19. Ramos P., Gieseg S. P., Schuster B., Esterbauer H. Effect of temperature on oxidation resistance of low-density lipoprotein. J. Lipid Res. 36:1995;2113-2129.
20. Kuzuya M., Yamada K., Hayashi T., Funaki C., Naito M., Asai K., Kanichi A., Kuzuya F. Role of lipoprotein-copper complex in copper catalyzed-peroxidation of low-density lipoprotein. Biochim. Biophys. Acta. 1123:1992;334-341.
21. Bowry V. W., Stocker R. Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein. J. Am. Chem. Soc. 115:1993;6019-6045.
22. Dubick M. A., Hunter G. C., Casey S. M., Keen C. L. Aortic ascorbic acid, trace elements, and superoxide dismutase activity in human aneurysmal disease. Proc. Soc. Exp. Biol. Med. 184:1987;138-143.
23. Smith C., Mitchinson M. J., Aruoma O. I., Halliwell B. Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions. Biochem. J. 286:1992;901-905.
24. Puhl H., Waeg G., Esterbauer H. Methods to determine oxidation of low-density lipoproteins. Methods Enzymol. 233:1994;425-441.
25. Van Reyk D. M., Brown A. J., Jessup W., Dean R. T. Batch-to-batch variation of chelex-100 confounds metal-catalysed oxidation. Leaching of inhibitory compounds from a batch of chelex-100 and their removal by a pre-washing procedure. Free Rad. Res. 23:1995;533-537.
26. Ziouzenkova O., Winklhofer-Roob B. M., Puhl H., Roob J. M., Esterbauer H. Lack of correlation between the α-tocopherol content of plasma and LDL, but high correlations for γ-tocopherol and carotenoids. J. Lipid Res. 37:1996;1936-1946.
27. Esterbauer H., Dieber-Rotheneder M., Striegl G., Waeg G. Role of vitamin E in preventing the oxidation of low density lipoprotein. Am. J. Clin. Nutr. 53:1991;314S-321S.
28. Kritharides L., Jessup W., Gifford J., Dean R. T. A method for defining the stages of low-density lipoprotein oxidation by the separation of cholesterol- and cholesterol ester-oxidation products using HPLC. Analyt. Biochem. 213:1993;79-89.
29. Sattler W., Mohr D., Stocker R. Rapid isolation of lipoproteins and assessment of their peroxidation by high-performance liquid chromatography postcolumn chemiluminiscence. Methods Enzymol. 233:1994;469-480.
30. 2+-catalysed oxidation. Biochem. J. 314:1996;577-585.
31. Witting P. K., Bowry V. W., Stocker R. Inverse deuterium kinetic isotope effect for peroxidation in human low-density lipoprotein (LDL). FEBS Lett. 375:1995;45-49.
32. Neuzil J., Thomas S. R., Stocker R. Requirement for, promotion, or inhibition by α-tocopherol of radical-induced initiation of plasma lipoprotein lipid peroxidation. Free Radic. Biol. Med. 22:1997;57-71.
33. Jialal I., Grundy S. M. Effect of dietary supplementation with alpha-tocopherol on the oxidative modification of low density lipoprotein. J. Lipid Res. 33:1992;899-906.
34. Esterbauer H., Striegl G., Puhl H., Rotheneder M. Continuous monitoring if in vitro oxidation of human low-density lipoprotein. Free Rad. Res. Comms. 6:1989;67-75.
35. Pifat G., Brnjas-Kraljevic J., Jürgens G., Herak-Kramberger C. M., Herak J. N. Chemical modification of low-density lipoprotein enhances the number of binding sites for divalent cations. Chem. Phys. Lipids. 63:1992;159-167.
36. Esterbauer H., Puhl H., Dieber-Rotheneder M., Waeg G., Rabl H. Effect of antioxidants on oxidative modification of LDL. Ann. Med. 23:1991;573-581.
37. Tribble D. L., van den Berg J. J. M., Motchnik P. A., Ames B. N., Lewis D. M., Chait A., Krauss R. M. Oxidative susceptibility of low density lipoprotein subfractions is related to their ubiquinol-10 and α-tocopherol content. Proc. Natl. Acad. Sci. USA. 91:1994;1183-1187.
38. Patel R. P., Svistunenko D., Wilson M. T., Darley-Usmar V. M. Reduction of Cu (II) by lipid hydroperoxides: Implications for the copper-dependent oxidation of low-density lipoprotein. Biochem. J. 322:1997;425-433.
39. Abuja P. M., Albertini P., Esterbauer H. Simulation of the induction of oxidation of low-density lipoprotein by high copper concentrations. Evidence for a nonconstant rate of initiation. Chem. Res. Tox. 10:1997;644-651.
40. Gießauf A., Steiner E., Esterbauer H. Early destruction of tryptophan residues of apolipoprotein B is a vitamin E-independent process during copper-mediated oxidation of LDL. Biochim. Biophys. Acta. 1256:1995;221-232.
41. Gießauf A., van Wickern B., Simat T., Steinhart H., Esterbauer H. Formation of N-formylkynurenine suggests the involvement of apolipoprotein B-100 centered tryptophan radicals in the initiation of LDL lipid peroxidation. FEBS Lett. 389:1996;136-140.
42. Bowry V. W., Ingold K. U., Stocker R. Vitamin E in human low-density lipoprotein - When and how this antioxidant becomes a pro-oxidant. Biochem. J. 288:1992;341-344.
43. Rice-Evans C., Leake D., Bruckdorfer K. R., Diplock A. T. Practical approaches to low density lipoprotein. Oxidation: Whys, wherefores and pitfalls. Free Rad. Res. 25:1996;285-311.