Structural flexibility modulates the activity of human glutathione transferase P1-1: Influence of a poor co-substrate on dynamics and kinetics of human glutathione transferase

Journal of Biological Chemistry

Volumn 271, Issue 27, 1996, Pages 16193-16198

  Caccuri, Anna Maria ^a   Ascenzi, Paolo ^b   Antonini, Giovanni ^c   Parker, Michael W ^d   Oakley, Aaron J ^d   Chiessi, Ester ^a   Nuccetelli, Marzia ^a   Battistoni, Andrea ^a   Bellizia, Anna ^a   Ricci, Giorgio ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b ROMA TRE UNIVERSITY   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; GLUTATHIONE TRANSFERASE; NITROBENZENE DERIVATIVE;

ARTICLE; BINDING SITE; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; HUMAN TISSUE; MOLECULAR MODEL; PLACENTA; PRIORITY JOURNAL; SPECTROPHOTOMETRY; THERMODYNAMICS; VISCOSITY;

4-CHLORO-7-NITROBENZOFURAZAN; BINDING SITES; DINITROCHLOROBENZENE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; KINETICS; MATHEMATICS; MODELS, STRUCTURAL; MODELS, THEORETICAL; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; THERMODYNAMICS;

FELIS CATUS; SIGANUS;

EID: 0030057817     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.27.16193     Document Type: Article

References (15)

1. Ricci, G., Caccuri, A. M., Lo Bello, M., Rosato, N., Mei, G., Nicotra, M., Chiessi, E., Mazzetti, A. P., and Federici, G. (1996) J. Biol. Chem. 271, 16187-16192
2. Ricci, G., Caccuri, A. M., Lo Bello, M., Pastore, A., Piemonte, F., and Federici, G. (1994) Anal. Biochem. 218, 463-465
3. Ivanetich, K. M., and Goold, R. D. (1989) Biochim. Biophys. Acta 998, 7-13
4. Lo Bello, M., Battistoni, A., Mazzetti, A. P., Board, P. G., Muramatsu, M., Federici, G., and Ricci, G. (1995) J. Biol. Chem. 270, 1249-1253
5. Lo Bello, M., Pastore, A., Petruzzelli, R., Parker, M. W., Wilce, M. C., Federici, G., and Ricci, G. (1993) Biochem. Biophys. Res. Commun. 194, 804-810
6. Habig, W. H., and Jakoby, W. B. (1981) Methods Enzymol. 77, 398-405
7. Segel, I. H. (1975) Enzyme Kinetics, John Wiley & Sons, New York
8. Ricci, G., Lo Bello, M., Caccuri, A. M., Pastore, A. Nuccetelli, M., Parker, M. W., and Federici, G. (1995) J. Biol. Chem. 270, 1243-1248
9. Coletta, M., Ascenzi, P., and Brunori, M. (1988) J. Biol Chem. 263, 18286-18289
10. Wolf, A. V., Brown, M. G., and Prentiss, P. G. (1985) Handbook of Chemistry and Physics (Weast, R. C., Astle, M. J., and Beyer, W. H., eds) pp. D-219-D-269, CRC Press, Inc., Boca Raton, FL
11. Menegatti, E., Guarneri, M., Bolognesi, M., Ascenzi, P., and Amiconi, G. (1985) Biochim. Biophys. Acta 832, 1-6
12. Caccuri, A. M., Ascenzi, P., Lo Bello, M., Federici, G., Battistoni, A., Mazzetti, A. P., and Ricci, G. (1994) Biochem. Biophys. Res. Commun. 200, 1428-1434
13. Graminski, G. F., Zhang, P., Sesay, M. A., Ammon, H. L., and Armstrong, R. N. (1989) Biochemistry 28, 6252-6258
14. Sampson, N. S., and Knowles, J. R. (1992) Biochemistry 31, 8488-8494
15. Reinemer, P., Dirr, H. W., Ladenstein, R., Huber, R., Lo Bello, M., Federici, G., and Parker, M. W. (1992) J. Mol. Biol. 227, 214-226