Structural flexibility modulates the activity of human glutathione transferase P1-1: Role of helix 2 flexibility in the catalytic mechanism

Journal of Biological Chemistry

Volumn 271, Issue 27, 1996, Pages 16187-16192

  Ricci, Giorgio ^a   Caccuri, Anna Maria ^a   Bello, Mario Lo ^a   Rosato, Nicola ^a   Mei, Giampiero ^a   Nicotra, Maria ^a   Chiessi, Ester ^a   Mazzetti, Anna P ^a   Federici, Giorgio ^b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; GLUTATHIONE TRANSFERASE;

ARTICLE; BINDING SITE; CATALYSIS; CIRCULAR DICHROISM; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; HUMAN TISSUE; MOLECULAR MODEL; PLACENTA; PRIORITY JOURNAL; SPECTROFLUOROMETRY; VISCOSITY;

BINDING SITES; CATALYSIS; CYSTEINE; DINITROCHLOROBENZENE; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; KINETICS; MATHEMATICS; MODELS, STRUCTURAL; MODELS, THEORETICAL; MUTAGENESIS, SITE-DIRECTED; PLACENTA; POINT MUTATION; PREGNANCY; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; VISCOSITY;

FELIS CATUS;

EID: 0030018850     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.27.16187     Document Type: Article

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