Growth inhibition by anti-estrogens and progestins in TGF-β-resistant and -sensitive breast-tumor cells

International Journal of Cancer

Volumn 65, Issue 5, 1996, Pages 682-687

  Kalkhoven, Eric ^a,c   Beraldi, Eliana ^a,b,d   Panno, M Luisa ^a,b,d   De Winter, Johan P ^a   Thussen, Jos H H ^b   Van Der Burg, Bart ^a  

^a HUBRECHT INSTITUTE   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d UNIVERSITY OF CALABRIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA ETHYL 21 HYDROXY 19 NORPREGN 4 ENE 3,20 DIONE; 4 HYDROXYTAMOXIFEN; ESTRADIOL; ETONOGESTREL; GESTODENE; ICI 161384; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; FEMALE; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

BREAST NEOPLASMS; CELL DIVISION; ESTROGEN ANTAGONISTS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GROWTH INHIBITORS; HUMANS; PROGESTINS; RECEPTORS, ESTROGEN; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0030004535     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19960301)65:5<682::AID-IJC20>3.0.CO;2-8     Document Type: Article

References (27)

1. ARRICK, B.A., KORC, M. and DERYNCK, R., Differential regulation of expression of the three transforming growth factor β species in human breast-cancer cell lines by estradiol. Cancer Res., 50, 299-303 (1990).
2. ARTEAGA, C.L., CARTY-DUGGER, T., MOSES, H.L., HURD, S.D. and PIETENPOL, J., Transforming growth factor β1 can induce estrogen-independent tumorigenicity of human breast-cancer cells in athymic mice. Cell Growth Diff., 4, 193-201 (1993a).
3. ARTEAGA, C.L., HURD, S.D., WINNIER, A.R., JOHNSON, M.D., FENDLEY, B.M. and FORBES, J.T., Anti-transforming growth factor (TGF)-β antibodies inhibit breast-cancer-cell tumorigenicity and increase mouse-spleen natural-killer-cell activity - implications for a possible role of tumor cell/host TGF-β interactions in human breast-cancer progression. J. clin. Invest., 92, 2569-2576 (1993b).
4. ARTEAGA, C.L., TANDON, A.K., VON HOFF, D.D. and OSBORNE, C.K., Transforming growth factor β: potential autocrine growth inhibitor of estrogen-receptor-negative human breast-cancer cells. Cancer Res., 48, 3898-3904 (1988).
5. BLANKENSTEIN, M.A., VAN DER MEULEN-DIJK, C. and THIJSSEN, J.H.H., Estrogen and progestin receptors in human meningioma cytosols using immunological methods Clin. chim. Acta, 165, 189-195 (1987).
6. BROWN, A.M.C., JELTSCH, J.-M., PETERS, M. and CHAMBON, P., Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7. Proc. nat. Acad. Sci. (Wash.), 81, 6344-6348 (1984).
7. CHOMCZYNSKI, P. and SACCHI, N., Single-step method of RNA isolation by acid-guanidinium-thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159 (1987).
8. CLARKE, C.L. and SUTHERLAND, R.L., Progestin regulation of cellular proliferation. Endocrine Rev., 11, 266-301 (1990).
9. COLLETTA, A.A., WAKEFILLD, L.M., HOWELL, F.V., DANIELPOUR, D., BAUM, M. and SPORN, M.B., The growth inhibition of human breast-cancer cells by a novel synthetic progestin involves the induction of transforming growth factor beta. J. clin. Invest., 87, 277-283 (1991).
10. DALAL, B.I., KEOWN, P.A. and GREENBERG, A.H., Immunocytochemical localization of secreted transforming growth factor-β to the advancing edges of primary tumors and to lymph-node metastases of human mammary carcinoma. J. Pathol., 143, 381-389 (1993).
11. DALY, R.J. and DARBRE, P.D., Cellular and molecular events in loss of estrogen sensitivity in ZR-75-1 and T-47-D human breast-cancer cells. Cancer Res., 50, 5868-5875 (1990).
12. FORT, P., MARTY, L., PIECHACZYK, M., ELSABROUTY, S., DNAI, C., JEANTEUR, P. and BLANCHARD, J.M., Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate dehydrogenase family. Nucleic Acid Res , 13, 1431-1442 (1985).
13. FREISS, G., PRÉBOIS, C. and VIGNON, F., Control of breast-cancer cell growth by steroids and growth factors - interactions and mechanisms. Breast Cancer Res. Treat., 27, 57-68 (1993).
14. FYNAN, T.M. and REISS, M., Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis. Crit. Rev. Oncogen., 4, 493-540 (1993).
15. GREEN, S., WALTER, P., KUMAR, V., KRUST, A., BORNERT, J.M., ARGOS, P. and CHAMBON, P., Human oestrogen receptor cDNA: sequence, expression, and homology to v-erb-A. Nature (Lond.), 320, 134-139 (1986).
16. HERMAN, M.E. and KATZENELLENBOGEN, B S., Alterations in transforming growth factor-α and -β production and cell responsiveness during progression of MCF-7 human breast-cancer cells to estrogen-autonomous growth. Cancer Res., 54, 5967-5874 (1994).
17. JI, H., STOUT, L.E., ZHANG, Q., ZHANG, R., LEUNG, H.T. and LEUNG, B.S., Absence of transforming-growth-factor-β responsiveness in the tamoxifen-growth-inhibited human breast-cancer cell line CAMA-1. J. cell. Biochem., 54, 332-342 (1994).
18. KALKHOVEN, E., KWAKKENBOS-ISBRUCKER, L., DE LAAT, S.W., VAN DER SAAG, P.T. and VAN DER BURG, B., Synthetic progestins induce proliferation of breast-tumor cells via the progesterone or estrogen receptor. Mol cell. Endocrinol., 102, 45-52 (1994).
19. KALKHOVEN, E., KWAKKENBOS-ISBRUCKER, L., MUMMERY, C.L., DE LAAT, S.W., VAN DEN EIJNDEN-VAN RAAIJ, A.J.M., VAN DER SAAG, P.T. and VAN DER BURG, B., The role of TGF-β production in growth inhibition of breast-tumor cells by progestins. Int. J. Cancer, 61, 80-86 (1995a).
20. KALKHOVEN, E., ROELEN, B.A.J., DE WINTER, J.P., L. MUMMERY, C.L., VAN DEN EIJNDEN-VAN RAAIJ, A.J.M., VAN DER SAAG, P.T. and VAN DER BURG, B., Resistance to TGF-β and activin due to reduced receptor expression in human breast-tumor cell lines. Cell Growth Diff., 6, 1151-1161 (1995b).
21. KNABBE, C., LIPPMAN, M.E., WAKEFIELD, L.M., FLANDERS, K.C., KASID, A., DERYNCK, R. and DICKSON, R.B., Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast-cancer cells. Cell, 48, 417-428 (1987).
22. LIN, H.Y. and MOUSTAKAS, A., Review: TGF-beta receptors: structure and function. Cell. mol. Biol., 40, 337-349 (1994).
23. MCCUNE, B.K., MULLIN, B.R., FLANDERS, K.C., JAFFURS, W.J., MULLEN, L.T., and SPORN, M.B., Localization of transforming growth factor-β isotypes in lesions of the human breast. Hum. Pathol., 23, 13-20 (1992).
24. OSBORNE, C.K. and FUQUA, S.A.W., Mechanisms of tamoxifen resistance. Breast Cancer Res. Treat, 32, 49-55 (1994).
25. ROBERTS, A.B. and SPORN, M.B., The transforming growth factor-betas. In: M.B. Sporn and A.B. Roberts (eds.), Peptide growth factors and their receptors. pp 419-472. Springer, Heidelberg (1990).
26. SUN, L , WU, G., WILLSON, J.K.V., ZBOROWSKA, E., YANG, J., RAJKARUNANAYAKE, I., WANG, J., GENTRY, L.E., WANG, X.-F. and BRATTAIN, M.G., Expression of transforming-growth-factor-β-type-II receptor leads to reduced malignancy in human breast-cancer MCF-7 cells. J. biol. Chem., 269, 26449-26455 (1994).
27. VAN DER BURG, B., RUTTEMAN, G.R., BLANKENSTEIN, M.A. and DE LAAT, S.W., Mitogenic stimulation of human breast-cancer cells in a growth-factor-defined medium: synergistic action of insulin and estrogen. J. cell. Physiol., 123, 101-108 (1988).