Opiate, cannabinoid, and eicosanoid signaling converges on common intracellular pathways nitric oxide coupling

Prostaglandins and Other Lipid Mediators

Volumn 57, Issue 1, 1999, Pages 23-34

  Fimiani, Caterina ^a   Liberty, Thomas ^a   Aquirre, Andrew J ^a   Amin, Irum ^a   Ali, Nabil ^a   Stefano, George B ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Aspirin; Cannabinoid; Eicosanoid; Morphine; Nitric oxide

Indexed keywords

ACETYLSALICYLIC ACID; ADENYLATE CYCLASE; ARACHIDONIC ACID; CANNABINOID; ICOSANOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; OPIATE; PHOSPHOLIPASE A2; PHOSPHOTRANSFERASE;

ARTICLE; CALCIUM TRANSPORT; ENZYME ACTIVITY; HUMAN; NEUROCHEMISTRY; NONHUMAN; RECEPTOR INTRINSIC ACTIVITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; CANNABINOIDS; EICOSANOIDS; HUMANS; NARCOTICS; NITRIC OXIDE; SIGNAL TRANSDUCTION;

EID: 0032983675     PISSN: 00906980     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-6980(98)00068-9     Document Type: Article

References (86)

1. Fitzgerald G.A. Prostaglandins and related compounds. Bennett J.C., Plumm F. Cecil Textbook of Medicine, 20th edn. 1996;1187 W.B. Saunders Company, Philadelphia.
2. Nasjletti A., McGiff J.C. Prostaglandins. Izzo J.L., Black H.R. Hypertension Primer. 1993;23 American Heart Association, Dallas, TX.
3. Nadler J.L. Lipoxygenase products. Izzo J.L., Black H.R. Hypertension Primer. 1993;25 American Heart Association, Dallas, TX.
4. Tetsuka T., Daphna-Iken D., Srivastava S.K., Baier L.D., DuMaine J., Morrison A.R. Cross-talk between cycloxygenase and nitric oxide pathways prostaglandin E2 negatively modulates induction of nitric oxide synthase by interleukin 1 . Proc Natl Acad Sci USA. 91:1994;12168.
5. La Pointe M.C., Sutkins J.R. Phospholipase A2 metabolites regulate inducible nitric oxide synthase in myocites. Hypertension. 31:(part 2):1998;218.
6. Salvemini D., Misko T.P., Masferrer J.L., Seibert K., Currie M.G., Needleman P. Nitric oxide activates cyclooxygenase enzymes. Proc Natl Acad Sci USA. 90:1993;7240.
7. Moncada S., Palmer R.M., Higgs E.A. Nitric oxide physiology, pathophysiology, and pharmacology . Pharmacol Rev. 43:(2):1991;109.
8. Schmidt H.H., Walter U. NO at work. Cell. 78:(6):1994;919.
9. Vane J.R., Mitchell J.A., Appleton I., et al. Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc Natl Acad Sci USA. 91:1994;2046.
10. McMillan K., Bredt D.S., Hirsch D.J., Snyder S.H., Clark J.E., Master B.S. Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds carbon monoxide. Proc Natl Acad Sci USA. 89:1992;11141.
11. Salvemini D., Seibert K., Masferrer J.L., Misko T.P., Currie M.G., Needleman P. Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J Clin Invest. 93:1994;1940.
12. Franchi A.M., Chaud M., Rettori V., Suburo A., McCann S.M., Gimeno M. Role of nitric oxide in eicosanoid synthesis and uterine motility in estrogen-treated rat uteri. Proc Natl Acad Sci USA. 91:1994;539.
13. Ristimaki A., Narko K., Hla T. Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone evidence for post-transcriptional regulation . Biochem J. 318:(Pt 1):1996;325.
14. Schaefers H.J., Goppelt-Struebe M. Interference of corticosteroids wirh prostaglandin E2 synthesis at the level of cyclooxygenase-2 mRNA expression in kidney cells. Biochem Pharmacol. 52:(9):1996;1415.
15. Kunz D., Walker G., Eberhardt W., Pfeilschifter J. Molecular mechanisms of dexamethasone inhibition of nitric oxide synthase expression in interleukin 1b-stimulated mesangial cells evidence for the involvement of transcriptional and posttranscriptional regulation . Proc Natl Acad Sci USA. 93:1996;255.
16. Burnstein S.H., Young J.K., Wright G.E. Relationships between eicosanoids and cannabinoids. Are eicosanoids cannabimimetic agents? Biochem Pharmacol. 50:(11):1995;1735.
17. Evans A.T., Formukong E.A., Evans F.J. Actions of cannabis constituents on enzymes of arachidonate metabolism antiinflammatory potential . Biochem Pharmacol. 36:1987;2035.
18. White H.L., Tansik R.L. Effects of Δ9-tetrahydrocannabinol and cannabinol on phospholipase and other enzymes regulating arachidonate metabolism. Prostaglandins Med. 4:1980;409.
19. Devane W.A., Hanus L., Breuer A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science. 258:1992;1946.
20. Stella N., Schweitzer P., Piomelli D. A second endogenous cannabinoid that modulates long-term potentiation. Nature. 388:1997;773.
21. Matsuda L.A., Lolait M.J., Young A.C., Bonner T.I. Structure of cannabinoid receptor and functional expression of the cloned cDNA. Nature (Lond). 346:1990;561.
22. Munro S., Thomas K.L., Abu-Shaar. Molecular characterization of a peripheral receptor for cannabinoid. Nature (Lond). 365:1993;61.
23. Diaz S., Specter S., Vanderhock J.Y., Coffey R.G. The effect of delta-9-tetrahydrocannabinol an arachidonic acid metabolism in human peripheral blood mononuclear cells. J Pharmacol Exp Ther. 268:(3):1994;1289.
24. Hunter S.A., Burstein S.H. Receptor mediation in cannabinoids stimulated arachidonic acid mobilization and anandamide synthesis. Life Sci. 60:1997;1563.
25. Randall M.D., Kendall D.A. Endocannabinoids a new class of vasoactive substances . Trends Pharmacol Sci. 19:1998;55.
26. Wagner J.A., Varga K., Ellis E.F., Rzigalinski B.A., Martin B.R., Kunos G. Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. Nature. 390:1997;518.
27. Deutsch D.G., Goligorsky M.S., Schmid P.C., et al. Production and physiological actions of anandamide in the vasculature of the rat kidney. J Clin Invest. 6:1997;1538.
28. Bilfinger T.V., Salzet M., Fimiani C., Deuttsch D.G., Stefano G.B. Pharmacological evidence for anandamide amidase in human cardiac and vascular tissues. Int J Cardiol. 64:(S1):1998;S3.
29. Mazzone A., Ricevuti G., Pasotti D., et al. Peptide opioids and morphine effects on inflammatory process. Inflammation. 14:(6):1990;717.
30. Stefano G.B., Scharrer B., Smith E.M., et al. Opioid and opiate immunoregulatory processes. Crit Rev Immunol. 16:1996;109.
31. Fukuda K., Kato S., Morikawa H., Shoda T., Mori K. Functional coupling of the delta-, mu-, and kappa-opioid receptors to mitogen-activated protein kinase and arachidonate release in Chinese hamster ovary cells. J Neurochem. 67:(3):1996;1309.
32. Sergeeva M.G., Terentjeva I.V., Mevkh A.T., Varfolomeev S.D. Direct influence of morphine on the release of arachidonic acid and its metabolites. FEBS Lett. 323:(1-2):1993;163.
33. Williams J.T. The painless synergism of aspirin and opium. Nature. 390:1997;557.
34. Vaughan C.W., Ingram S.L., Connor M.A., Christie M.J. How opioids inhibit GABA-mediated neurotransmission. Nature. 390:1997;611.
35. Zadina J.E., Hackler L., Ge L.J., Kastin A.J. A potent and selective endogenous agonist for the μ-opiate receptor. Nature. 386:1997;499.
36. Stefano G.B., Sharrer B. Endogenous morphine and related opiates, a new classof chemical messengers. Adv Neuroimmunol. 4:1994;57.
37. Magazine H.I., Liu Y., Fricchione G.L., Stefano G.B. Morphine induced conformational changes in human monocytes, granulocytes, and endothelial cells and in invertebrate immunocytes and microglia are mediated by nitric oxide. J Immunol. 156:1996;4845.
38. Stefano G.B., Liu Y., Goligorsky M.S. Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. J Biol Chem. 271:(32):1996;19238.
39. Leslie C.C. Properties and regulation of cytosolic phospholipase A2. J Biol Chem. 272:1997;16709.
40. Wu T., Levine S.J., Lawrence M.G., Logun C., Angus C.W., Shelhamer J.H. Interferon-gamma induces the synthesis and activation of cytosolic phospholipase A2. J Clin Invest. 93:1994;571.
41. Tay A., Maxwell P., Li Z.G., Goldberg H., Skorecki K. Cytosolic phospholipase A2 gene expression in rat mesangial cells is regulated post-transcriptionally. Biochem J. 304:1994;417.
42. 2 is phosphorylated and activated by MAP kinase. Cell. 72:(2):1993;269.
43. De Carvalho M.G., McCormack A.L., Olson E., et al. Identification of phosphorylation sites of human 85-kDa cytosolic phospholipase A2 expressed in insect cells and present in human monocytes. J Biol Chem. 271:1996;6987.
44. Wheeler-Jones C., Abu-Ghazaleh R., Cospedal R., Houliston R.A., Martin J., Zachary I. Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42/p44 mitogen-activated protein kinase. FEBS Lett. 420:1997;28.
45. Qiu Z.H., Leslie C.C. Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2. J Biol Chem. 269:1994;19480.
46. Clark J.D., Schievella A.R., Nalefski E.A., Lin L.L. Cytosolic phospholipase A2. J Lipid Mediat Cell Signal. 12:1995;83.
47. Wartmann M., Campbell D., Subramanian A., Burstein S.H., Davis R.J. The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide. FEBS Lett. 359:(2-3):1995;133.
48. Li L., Chang K.J. The stimulatory effect of opioids on mitogen activated protein kinase in Chinese hamster ovary cells transfected to express mu-opioid receptors. Mol Pharmacol. 50:(3):1996;599.
49. Gutstein H.B., Rubie E.A., Mansour A., Akil H., Woodgett J.R. Opioid effects on mitogen-activated protein kinase signaling cascades. Anestesiology. 87:(5):1997;1118.
50. Twitchell W., Brown S., Mackie K. Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. J Neurophysiol. 78:(1):1997;43.
51. Bourinet E., Soong T.W., Stea A., Snutch T.P. Determinants of the G protein-dependent opioid modulation of neuronal calcium channels. Proc Natl Acad Sci USA. 93:(4):1996;1486.
52. Sugiura T., Kodaka T., Kondo S., et al. 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. Biochem Biophys Res Commun. 229:(1):1996;58-64.
53. Sugiura T., Kodaka T., Kondo S., et al. Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca2+ transient in NG108-15 cells. J Biochem (Tokyo). 122:(4):1997;890.
54. Hauser K.F., Stiene-Martin A., Mattson M.P., Elde R.P., Ryan S.E., Godleske C.C. mu-Opioid receptor-induced Ca2+ mobilization and astroglial development morphine inhibits DNA synthesis and stimulates cellular hypertrophy through a Ca2+-dependent mechanism . Brain Res. 720:(1-2):1996;191.
55. De Petrocellis L., Orlando P., Di Marzo V. Anandamide, an endogenous cannabinomimetic substance, modulates rat brain protein kinase c in vitro. Biochem Mol Biol Int. 36:(6):1995;1127.
56. Chen Y., Yu L. Differential regulation by cAMP-dependent protein kinase and protein kinase C of the mu opioid receptor coupling to a G protein activated K+ channel. J Biol Chem. 269:(11):1994;7839.
57. Wan Y., Kurosaki T., Huang X.Y. Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors. Nature. 380:(6574):1996;541.
58. Lepley R.A., Muskardin D.T., Fitzpatrick F.A. Tyrosine kinase activity modulates catalysis and translocation of cellular 5-lipoxygenase. J Biol Chem. 271:(11):1996;6179.
59. Rettori V., Aguila M.C., Gimeno M.F., Franchi A.M., McCann S.M. In vitro effect of Δ9- tetrahydrocannabinol to stimulate somatostatin release and block that of luteinizing hormone-releasing hormone by suppression of the release of prostaglandin E2. Proc Natl Acad Sci USA. 87:1990;10063.
60. Elliot G.R., van Batenburg M.J., Dzoljic M.R. Enhanced prostaglandin E2 and tromboxane B2 release from resident peritoneal macrophages isolated from morphine-dependent rats. FEBS Lett. 217:1987;6.
61. Pasotti D., Mazzone A., Lecchini S., Frigo G.M., Ricevuti G. The effect of opioid peptides on peripheral blood granulocytes. Riv Eur Sci Med Farmacol. 15:(2):1993;71.
62. 5]-enkephalin. J Pharmacol Exp Ther. 263:(2):1992;527.
63. Zhong F., Li X.Y., Stefano G.B., Fimiani C., Bilfinger T. Methionine-enkephalin stimulates interleukin-6 mRNA expression human plasma levels in coronary artery bypassing grafting . Int J Cardiol. 64:(S1):1998;S53.
64. Min B.H., Augustin L.B., Felsheim R.F., Fuchs J.A., Loh H.H. Geonomic structure and analysis of promoter sequence of a mouse μ opioid receptor gene. Proc Natl Acad Sci USA. 91:1994;9081.
65. Shipp M.A., Stefano G.B., D'Adamio L., et al. Downregulation of enkephalin-mediated inflammatory response by CD10/neutral endopeptidase 24.11. Nature. 347:1990;394.
66. Williams J.A., Shacter E. Regulation of macrophage cytokine production by prostaglandin E2. Distinct roles of cyclooxygenase-1 and -2. J Biol Chem. 272:(41):1997;25693.
67. Huang P.L., Dawson T.M., Bredt D.S., Snyder S.H., Fishman M.C. Targeted disruption of the neuronal nitric oxide synthase gene. Cell. 75:1993;1273.
68. Anggard E. Nitric oxide mediator, murderer, and medicine . Lancet. 343:1994;1199.
69. Yun H.Y., Dawson V.L., Dawson T.M. Neurobiology of nitric oxide. Crit Rev Neurobiol. 10:1996;291.
70. Radomski M.W., Palmer R.M.J., Moncada S. Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. Proc Natl Acad Sci USA. 87:1990;10043.
71. Huang P.L., Huang Z., Mashimo H., et al. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature. 377:1995;239.
72. Topper J.N., Cai J., Falb D., Gimbrone M.A. Jr. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress . Proc Natl Acad Sci USA. 93:1996;10417.
73. Bilfinger T.V., Hartman A., Liu Y., Magazine H.I., Stefano G.B. Cryopreserved veins used for myocardial revascularization a 5 year experience and a possible mechanism for their increased failure . Ann Thorac Surg. 63:1997;1063.
74. De Vera M.E., Shapiro R.A., Nussler A.K., et al. Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines initial analysis of the human NOS2 promoter . Proc Natl Acad Sci USA. 93:1996;1054.
75. Stefano G.B., Digenis A., Spector S., et al. Opiate-like substances in an invertebrate, an opiate receptor on invertebrate and human immunocytes, and a role in immunosuppression. Proc Natl Acad Sci USA. 90:(23):1993;11099.
76. Makman M.H., Bilfinger T.V., Stefano G.B. Human granulocytes contain an opiate alkaloid-selective receptor mediating inhibition of cytokine-induced activation and chemotaxis. J Immunol. 154:1995;1323.
77. Stefano G.B., Hartman A., Bilfinger T.V., et al. Presence of the μ3 opiate receptor in endothelial cells. J Biol Chem. 270:(51):1995;30290.
78. Togashi H., Sasaki M., Frohman E., et al. Neuronal (type I) nitric oxide synthase regulates nuclear factor kb activity and immunologic (type II) nitric oxide synthase expression. Proc Natl Acad Sci USA. 94:1997;2676.
79. Roy S., Cain K.J., Chapin R.B., Charboneau R.G., Barke R.A. Morphine modulates NF kappa B activation in macrophages. Biochem Biophys Commun. 245:(2):1998;392.
80. Sen C.K., Roy S., Packer L. Involvement of intracellular Ca2+ in oxidant-induced NF-kappa B activation. FEBS Lett. 385:(1-2):1996;58.
81. Pahl H.L., Baeuerle P.A. Activation of NF-kappa B by ER stress requires both Ca2+ and reactive oxygen intermediates as messengers. FEBS Lett. 392:(2):1996;129.
82. Stefano G.B., Salzet M., Magazine H.I., Bilfinger T.V. Antagonism of LPS and INF γ induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase. J Cardiovasc Pharmacol. 31:(6):1998;1.
83. Kwon G., Hill J.R., Corbett J.A., McDaniel M.L. Effects of aspirin on nitric oxide formation and de novo protein synthesis by RINm5F cells and rat islets. Mol Pharmacol. 52:(3):1997;398.
84. Farivar R.S., Chobanian A.V., Brecher P. Salicylate or aspirin inhibits the induction of the inducible nitric oxide synthase in rat cardiac fibroblast. Circ Res. 78:(5):1996;759.
85. Fricchione G.L., Bilfinger T.V., Stefano G.B. Aspirin inhibts granulocyte and monocyte adherence to saphenous vein endothelia in a process not mediated by nitric oxide. Int J Cardiol. 64:(S1):1998;S29.
86. Tønnesen E., Brix-Christensen V., Bilfinger T.V., Sanchez R.G., Stefano G.B. Endogenous morphine levels increase following cardiac surgery as part of the antiinflammatory response. J Int Cardiology. 62:1997;191.