Short-term effects of transdermal estrogen replacement therapy on coronary vascular reactivity in postmenopausal women with angina pectoris and normal results on coronary angiograms

Journal of the American College of Cardiology

Volumn 31, Issue 1, 1998, Pages 139-143

  Roqué, Mercè ^a   Heras, Magda ^a   Roig, Eulàlia ^a   Masotti, Mònica ^a   Rigol, Montserrat ^a   Betriu, Amadeu ^a   Balasch, Juan ^a   Sanz, Ginés ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ESTRADIOL; ESTROGEN; GLUCOSE; GLYCERYL TRINITRATE;

ADULT; AGED; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ARTERY DIAMETER; ARTERY ENDOTHELIUM; ARTICLE; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; CORONARY VASCULAR RESISTANCE; DOSE RESPONSE; DRUG EFFECT; ESTROGEN THERAPY; FEMALE; HUMAN; POSTMENOPAUSE; PRIORITY JOURNAL; TRANSDERMAL DRUG ADMINISTRATION; VASOCONSTRICTION;

AGED; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; FEMALE; HUMANS; MICROVASCULAR ANGINA; MIDDLE AGED; POSTMENOPAUSE; REGIONAL BLOOD FLOW; VASCULAR RESISTANCE;

EID: 0031951052     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(97)00436-1     Document Type: Article

References (31)

1. Barrett-Connor E, Bush TL. Estrogen and coronary heart disease in women. JAMA. 265:1991;1861-1867.
2. Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. JAMA. 273:1995;199-208.
3. Moreno GT, Manson JE. Cholesterol and coronary heart disease in women an overview of primary and secondary prevention . Coronary Heart Dis. 4:1993;580-587.
4. Eaker ED, Chesebro JH, Sacks FM, Wenger NK, Whisnant JP, Winston M. Cardiovascular disease in women. Circulation. 88:1993;1999-2008.
5. Collins P. Endothelial dysfunction in patients with chest pain and angiographically normal coronaries. Kaski JC. Angina Pectoris With Normal Coronary Arteries Syndrome X . 1995;167-174 Kluwer Academic, Boston.
6. L'Abbate A, Camici PG, Reisenhofer B. Abnormal coronary flow reserve in syndrome X a critical view to the concept of vasodilator reserve and its relation to ischemia . Coronary Artery Dis. 3:1992;579-585.
7. Camici PG, Gistri R, Lorenzoni R, et al. Coronary reserve and exercise ECG in patients with chest pain and normal coronary arteriograms. Circulation. 86:1992;179-188.
8. Mosseri M, Yarom R, Gotsman MS, Hasin Y. Histologic evidence for small-vessel coronary artery disease in patients with angina pectoris and patent large coronary arteries. Circulation. 74:1986;964-972.
9. Cannon RO, Epstein SE. "Microvascular angina" as a cause of chest pain with angiographically normal coronary arteries. Am J Cardiol. 61:1988;1338-1343.
10. Rosano GMC, Kaski JC, Lindsay DC, Collins P, Sarrel PM, Poole-Wilson PA. Syndrome X in women is associated with estrogen deficiency. Eur Heart J. In press.
11. Sullivan JM. Hormone replacement therapy and cardiovascular disease the human model . Br J Obstet Gynaecol. 103:1996;59-67.
12. Matthews KA, Kuller LH, Wing RR, Meilahn EN, Plantinga P. Prior to use of estrogen replacement therapy, are users healthier than nonusers? Am J Epidemiol. 143:1996;971-978.
13. Herrington DM, Braden GA, Williams K, Morgan TM. Endothelial-dependent coronary vasomotor responsiveness in postmenopausal women with and without estrogen replacement therapy. Am J Cardiol. 73:1994;951-952.
14. Lieberman EH, Gerhard MD, Uehata A, et al. Estrogen improves endothelium-dependent flow-mediated vasodilation in postmenopausal women. Ann Intern Med. 121:1995;936-941.
15. Reis SE, Gloth ST, Blumenthal RS, et al. Ethinyl estradiol acutely attenuates abnormal coronary vasomotor responses to acetylcholine in postmenopausal women. Circulation. 89:1994;52-60.
16. Mancini GJB, Simon SB, McGillem MJ, LeFree MT, Friedman HZ, Vogel RA. Automated quantitative coronary arteriography morphologic and physiologic validation in vivo of a rapid digital angiographic method . Circulation. 75:1987;452-460.
17. Gilligan DM, Badar DM, Panza JA. Effects of estrogen replacement therapy on peripheral vasomotor function in postmenopausal women. Am J Cardiol. 75:1996;264-268.
18. Rosano G, Sarrel PM, Poole-Wilson PA, Collins P. Beneficial effect of oestrogen on exercise-induced myocardial ischaemia in women with coronary artery disease. Lancet. 342:1993;133-136.
19. Rosano G, Peters NS, Lefroy D, et al. 17-Beta-estradiol therapy lessens angina in postmenopausal women with syndrome X. J Am Coll Cardiol. 28:1996;1500-1505.
20. Campos H, Wilson PWF, Jiménez D, McNamara JR, Ordovas J, Schaefer EJ. Differences in apolipoproteins and low density lipoprotein subfractions in postmenopausal women on and off estrogen therapy results from the Framingham Offspring Study . Metabolism. 39:1990;1033-1038.
21. Solymoss BC, Marcil M, Wesolowska E, Gilfix BM, Lespérance J, Campeau L. Relation of coronary artery disease in women <60 years of age to the combined elevation of serum lipoprotein(a) and total cholesterol to high-density cholesterol ratio. Am J Cardiol. 72:1993;1215-1218.
22. Samaan SA, Crawford MH. Estrogen and cardiovascular function after menopause. J Am Coll Cardiol. 26:1995;1403-1410.
23. Cheng DY, Gruetter CA. Chronic estrogen alters contractile responsiveness to angiotensin II and norepinephrine in female rat aorta. Eur J Pharmacol. 215:1992;171-177.
24. Jiang C, Sarrel PM, Poole-Wilson PA, Collins P. Acute effect of 17-estradiol on rabbit coronary artery contractile responses to endothelin-1. Am J Physiol. 263:1992;H271-H275.
25. Jiang C, Sarrel PM, Lindsay DC, Poole-Wilson PA, Collins P. Endothelium-independent relaxation of rabbit coronary artery by 17-estradiol in vitro. J Pharmacol. 104:1991;1033-1037.
26. Hayashi T, Fukuto JM, Ignarro LJ, Chaudhuri G. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits implications for atherosclerosis . Proc Natl Acad Sci. 89:1992;11259-11263.
27. Maddox YT, Falcon JG, Ridinger M, Cunard CM, Ramwell PW. Endothelium-dependent gender differences in the response of the rat aorta. J Pharmacol Exp Ther. 240:1987;392-395.
28. Losordo DW, Kearney M, Kim EA, Jekanowski J, Isner JM. Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of premenopausal women. Circulation. 89:1994;1501-1510.
29. Keaney JF, Shwaery GT, Xu A, et al. 17-Beta-estradiol preserves endothelial vasodilator function and limits low-density lipoprotein oxidation in hypercholesterolemic swine. Circulation. 89:1994;2251-2259.
30. Harrison DG, Ohara Y. Physiologic consequences of increased vascular oxidant stresses in hypercholesterolemia and atherosclerosis implications for impaired vasomotion . Am J Cardiol. 75:1995;75B-81B.
31. Rubanyi GM, Vanhoutte PM. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol. 250:1986;H822-H827.