Effects of 17β-oestradiol on rat isolated coronary and mesenteric artery tone: Involvement of nitric oxide

Journal of Pharmacy and Pharmacology

Volumn 50, Issue 5, 1998, Pages 531-538

  Otter, Donna ^a   Austin, Clare ^a  

^a MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ESTRADIOL; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; POTASSIUM CHLORIDE; PROSTAGLANDIN; ANTIESTROGEN; ENZYME INHIBITOR; NITRIC OXIDE SYNTHASE; VASOCONSTRICTOR AGENT;

ANIMAL TISSUE; ARTERY DILATATION; ARTERY TONE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; DOSE RESPONSE; HORMONE SUBSTITUTION; MALE; MESENTERIC ARTERY; NONHUMAN; PROSTAGLANDIN SYNTHESIS; RAT; RESISTANCE BLOOD VESSEL; ANIMAL; COMPARATIVE STUDY; CORONARY BLOOD VESSEL; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE; VASODILATATION; WISTAR RAT;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; CORONARY VESSELS; DRUG SYNERGISM; ENZYME INHIBITORS; ESTRADIOL; ESTRADIOL ANTAGONISTS; MALE; MESENTERIC ARTERIES; MUSCLE, SMOOTH, VASCULAR; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RATS; RATS, WISTAR; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 0031595222     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1998.tb06195.x     Document Type: Article

References (35)

1. Abraham, G. E., Odell, W. D., Swerdloff, R. S., Hopper, K. (1972) Simultaneous radioimmunoassay of plasma FSH, LH, progesterone, 17-hydroxyprogesterone, and estradiol-17β during the menstrual cycle. J. Clin. Endocrinol. Metab. 34: 312-316
2. Adams, M. R., Kaplan, J. R., Manuck, S. B., Kortnik, D. R., Parks, J. S., Wolfe, M. S., Clarkson, T. B. (1990) Inhibition of coronary artery atherosclerosis by 17β-estradiol in ovariectomized monkeys: lack of an effect of added progesterone. Atherosclerosis 10: 1051-1057
3. Barker, J. E., Bakhle, Y. S., Anderson, J., Treasure, T., Piper, P. J. (1996) Reciprocal inhibition of nitric oxide and prostacyclin synthesis in human saphenous vein. Br. J. Pharmacol. 118: 643-648
4. Barrett-Connor, E., Bush, T. L. (1991) Estrogen and coronary heart disease in women. J. Am. Med. Assoc. 265: 1861-1867
5. Bayard, P., Clamens, S., Delsol, G., Blaes, N., Maret, A., Faye, J.-C. (1995) Oestrogen synthesis, oestrogen metabolism and functional oestrogen receptors in bovine aortic endothelial cells. In: Non-reproductive Actions of Sex Steroids. Ciba Foundation Symposium, 191: 122-132
6. Bolton, T. B., Lang, R. J., Takewaki, T. (1984) Mechanisms of action of noradrenaline and carbachol on smooth muscle of guinea-pig anterior mesenteric artery. J. Physiol. 351: 549-572
7. Bush, T. L., Barrett-Connor, E., Cowan, L. D., Criqui, M. H., Wallace, R. B., Suchinddran, C. M., Tyroler, H. A., Rifkind, B. M. (1987) Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program follow-up study. Circulation 75: 1102-1109
8. Chester, A. H., Jiang, C., Borland, J. A., Yacoub, M. H., Collins, P. (1995) Oestrogen relaxes human epicardial coronary arteries through non-endothelium-dependent mechanisms. Coron. Artery Dis. 6: 417-422
9. Coburn, P., Buonassisi, V. (1978) Estrogen binding sites in endothelial cell cultures. Science 201: 817-819
10. Collins, P., Rosano, G. M. C., Sarrel, P. M., Ulrich, L., Adamopoulos, S., Beale, C. M., McNeill, J. G., Poole-Wilson, P. A. (1995) 17β-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease. Circulation 92: 24-30
11. Corvazier, E., Dupuy, E., Dosne, A. M., Maclouf, J. (1984) Minimal effect of oestrogens on endothelial cell growth and production of prostacyclin. Thromb. Res. 34: 303-310
12. Gilligan, D. M., Badar, D. M., Panza, J. A., Quyyumi, A. A., Cannon, R. O. (1994) Acute vascular effects of estrogen in post-menopausal women. Circulation 90: 786-791
13. Gilligan, D. M., Badar, D. M., Panza, J. A., Quyyumi, A. A., Cannon, R. O. (1995) Effects of estrogen replacement therapy on peripheral vasomotor function in post-menopausal women. Am. J. Cardiol. 75: 264-268
14. Gisclard, V., Miller, V. M., Vanhoutte, P. M. (1988) Effect of 17 β-oestradiol on endothelium-dependent responses in the rabbit. J. Pharmacol. Exp. Ther. 244: 19-22
15. 2 in porcine coronary artery. Circulation 91: 2619-2626
16. Horowitz, K. B., Horowitz, I. D. (1982) Canine vascular tissues are targets for androgens, estrogens, progestins and glucocorticoids. J. Clin. Invest. 69: 750-759
17. Jiang, C., Sarrel, P. M., Lindsay, D. C., Poole-Wilson, P. A., Collins, P. (1991) Endothelium-independent relaxation of rabbit coronary artery by 17β-oestradiol in vitro. Br. J. Pharmacol. 104: 1033-1037
18. Kitazawa, T., Hamada, E., Kitazawa, K., Gaznabi, A. K. M. (1997) Non-genomic mechanism of 17 beta-oestradiol-induced inhibition of contraction in mammalian vascular smooth muscle. J. Physiol. 499: 497-511
19. Lavigne, M. C., Bei, M., Foegh, M. L., Ramwell, P. W., Clarke, R. (1995) Specific binding of estradiol to rat coronary artery smooth muscle cells. Fed. Am. Soc. Exp. Biol. J. 9: A315
20. Lin, A. L., Gonzalez, R., Carey, K. D., Shain, S. A. (1986) Estradiol 17β affects estrogen receptor distribution and elevates progesterone receptor content in baboon aorta. Arteriosclerosis 6: 495-504
21. Losordo, D. W., Kearney, M., Kim, E. A., Jekanowski, J., Isner, J. M. (1994) Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of pre-menopausal women. Circulation 89: 1501-1510
22. Magness, R. R., Rosenfeld, C. R. (1989) Local and systemic estradiol-17 beta: effects on uterine and systemic vasodilation. Am. J. Physiol. 256: E536-E542
23. Merrlam, G. R., MacLusky, N. J., Johnson, L. A., Naftolin, F. (1980) 2-Hydroxyestradiol-17α and 4-hydroxyestradiol-17α, catechol estrogen analogs with reduced estrogen receptor affinity. Steroids 36: 13-20
24. Mikkola, T., Turunen, P., Avela, K., Orpana, A., Viinikka, L., Ylikorkala, O. (1995) 17β-Estradiol stimulates prostacyclin, but not endothelin-1, production in human vascular endothelial cells. J. Clin. Endocrinol. Metab. 80: 1832-1836
25. Mugge, A., Riedel, M., Barton, M., Kuhn, M., Lichtlen, P. R. (1993) Endothelium independent relaxation of human coronary arteries by 17 β-oestradiol in vitro. Cardiovasc. Res. 27: 1939-1942
26. Mulvany, M. J., Halpern, W. (1977) Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ. Res. 41: 19-26
27. Orimo, A., Inoue, S., Ikegami, A., Hosoi, T., Akishita, M., Ouchi, Y., Muramatsu, M., Orimo, H. (1993) Vascular smooth muscle cells as target for estrogen. Biochem. Biophys. Res. Commun. 195: 730-736
28. Raddino, R., Manca, C., Poli, E., Bolognesi, R., Visioli, O. (1986) Effects of 17 beta-estradiol on the isolated rabbit heart. Arch. Int. Pharmacodyn. Ther. 281: 57-65
29. Reis, S. E., Gloth, S. T., Blumenthal, R. S., Resar, J. R., Zacur, H. A., Gerstenblith, G., Blinker, J. A. (1994) Ethinyl estradiol attenuates abnormal vasomotor responses to acetylcholine in post-menopausal women. Circulation 89: 52-60
30. Rosenfeld, C. R., Cox, B. E., Roy, T., Magness, R. R. (1996) Nitric oxide contributes to estrogen-induced vasodilation of the ovine uterine circulation. J. Clin. Invest. 98: 2158-2166
31. Salas, E., Lopez, M. G., Villarroya, M., Sanchez-Garcia, P., DePascul, R., Dixon, W. R., Garcia, A. G. (1994) Endothelium-independent relaxation by 17α-estradiol of pig coronary arteries. Eur. J. Pharmacol. 258: 47-55
32. Stampfer, M. J., Colditz, G. A., Willett, W. C., Manson, J. E., Rosner, B., Speizer, F. E., Hennekens, C. H. (1991) Post-menopausal estrogen therapy and cardiovascular disease: ten year follow-up from the Nurses Health Study. N. Eng. J. Med. 325: 756-762
33. Sudhir, K., Jennings, G. L., Funder, J. W., Komesaroff, P. A. (1996) Estrogen enhances basal nitric oxide release in the forearm vasculature in perimenopausal women. Hypertension 28: 330-334
34. Williams, J. K., Adams, M. R., Klopfenstein, H. S. (1990) Estrogen modulates responses of atherosclerotic coronary arteries. Circ. Res. 81: 1680-1687
35. Williams, S. P., Shackelford, D. P., Iams, S. C., Mustafa, S. J. (1988) Endothelium-dependent relaxation in estrogen-treated spontaneously hypertensive rats. Eur. J. Pharmacol. 145: 205-207