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Volumn 11, Issue 4, 1999, Pages 453-462

Quantitative analysis of the T cell repertoire that escapes negative selection

Author keywords

[No Author keywords available]

Indexed keywords

EGG WHITE; LYSOZYME;

EID: 0033213226     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80120-X     Document Type: Article
Times cited : (92)

References (56)
  • 1
    • 0032103935 scopus 로고    scopus 로고
    • Generation of an MHC class II-restricted T cell epitope by extracellular processing of hepatitis delta antigen
    • Accapezzato, D., Nisini, R., Paroli, M., Bruno, G., Bonino, F., Houghton, M., and Barnaba, V. (1998). Generation of an MHC class II-restricted T cell epitope by extracellular processing of hepatitis delta antigen. J. Immunol. 160, 5262-5266.
    • (1998) J. Immunol. , vol.160 , pp. 5262-5266
    • Accapezzato, D.1    Nisini, R.2    Paroli, M.3    Bruno, G.4    Bonino, F.5    Houghton, M.6    Barnaba, V.7
  • 3
    • 0024206747 scopus 로고
    • Mechanisms influencing the immunodominance of T cell determinants
    • Adorini, L., Appella, E., Doria, G., and Nagy, Z.A. (1988). Mechanisms influencing the immunodominance of T cell determinants. J. Exp. Med. 168, 2091-2104.
    • (1988) J. Exp. Med. , vol.168 , pp. 2091-2104
    • Adorini, L.1    Appella, E.2    Doria, G.3    Nagy, Z.A.4
  • 4
    • 0030852519 scopus 로고    scopus 로고
    • A range of CD4 T cell tolerance: Partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis
    • Akkaraju, S., Ho, W.Y., Leong, D., Canaan, K., Davis, M.M., and Goodnow, C.C. (1997). A range of CD4 T cell tolerance: Partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis. Immunity 7, 255-271.
    • (1997) Immunity , vol.7 , pp. 255-271
    • Akkaraju, S.1    Ho, W.Y.2    Leong, D.3    Canaan, K.4    Davis, M.M.5    Goodnow, C.C.6
  • 5
    • 0021741202 scopus 로고
    • Processing and presentation of hen egg-white lysozyme by macrophages
    • Allen, P.M., and Unanue, E.R. (1984). Processing and presentation of hen egg-white lysozyme by macrophages. Immunobiology 168, 182-188.
    • (1984) Immunobiology , vol.168 , pp. 182-188
    • Allen, P.M.1    Unanue, E.R.2
  • 6
    • 0032482173 scopus 로고    scopus 로고
    • Exogenously provided peptides of a self-antigen can be processed into forms that are recognized by self-T cells
    • Barlow, A.K., He, X., and Janeway, C. (1998). Exogenously provided peptides of a self-antigen can be processed into forms that are recognized by self-T cells. J. Exp. Med. 187, 1403-1415.
    • (1998) J. Exp. Med. , vol.187 , pp. 1403-1415
    • Barlow, A.K.1    He, X.2    Janeway, C.3
  • 8
    • 0030067815 scopus 로고    scopus 로고
    • The class II MHC l-Ag7 molecules from non-obese diabetic mice are poor peptide binders
    • Carrasco-Marin, E., Shimizu, J., Kanagawa, O., and Unanue, E.R. (1996). The class II MHC l-Ag7 molecules from non-obese diabetic mice are poor peptide binders. J. Immunol. 156, 450-458.
    • (1996) J. Immunol. , vol.156 , pp. 450-458
    • Carrasco-Marin, E.1    Shimizu, J.2    Kanagawa, O.3    Unanue, E.R.4
  • 9
    • 0030802693 scopus 로고    scopus 로고
    • T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage
    • Carson, R.T., Vignali, K.M., Woodland, D.L., and Vignali, D.A. (1997). T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage. Immunity 7, 387-399.
    • (1997) Immunity , vol.7 , pp. 387-399
    • Carson, R.T.1    Vignali, K.M.2    Woodland, D.L.3    Vignali, D.A.4
  • 10
    • 0029043886 scopus 로고
    • Low avidity recognition of a class II-restricted neo-self peptide by virus-specific T cells
    • Cerasoli, D.M., McGrath, J., Carding, S.R., Shih, F.F., Knowles, B.B., and Caton, A.J. (1995). Low avidity recognition of a class II-restricted neo-self peptide by virus-specific T cells. Int. Immunol. 7, 935-945.
    • (1995) Int. Immunol. , vol.7 , pp. 935-945
    • Cerasoli, D.M.1    McGrath, J.2    Carding, S.R.3    Shih, F.F.4    Knowles, B.B.5    Caton, A.J.6
  • 12
    • 0030745938 scopus 로고    scopus 로고
    • Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody
    • Dadaglio, G., Nelson, C.A., Deck, M.B., Petzold, S.J., and Unanue, E.R. (1997). Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody. Immunity 6, 727-738.
    • (1997) Immunity , vol.6 , pp. 727-738
    • Dadaglio, G.1    Nelson, C.A.2    Deck, M.B.3    Petzold, S.J.4
  • 13
    • 0027439013 scopus 로고
    • An autoantigenic T cell epitope forms unstable complexes with class II MHC: A novel route for escape from tolerance induction
    • Fairchild, P.J., Wildgoose, R., Atherton, E., Webb, S., and Wraith, D.C. (1993). An autoantigenic T cell epitope forms unstable complexes with class II MHC: A novel route for escape from tolerance induction. Int. Immunol. 5, 1151-1158.
    • (1993) Int. Immunol. , vol.5 , pp. 1151-1158
    • Fairchild, P.J.1    Wildgoose, R.2    Atherton, E.3    Webb, S.4    Wraith, D.C.5
  • 14
    • 0024293245 scopus 로고
    • Crystallization and preliminary x-ray diffraction studies of two new antigen-antibody (lysozyme-Fab) complexes
    • Fischmann, T., Souchon, H., Riottot, M.M., Tello, D., and Poljak, R.J. (1988). Crystallization and preliminary x-ray diffraction studies of two new antigen-antibody (lysozyme-Fab) complexes. J. Mol. Biol. 203, 527-529.
    • (1988) J. Mol. Biol. , vol.203 , pp. 527-529
    • Fischmann, T.1    Souchon, H.2    Riottot, M.M.3    Tello, D.4    Poljak, R.J.5
  • 15
    • 0024428816 scopus 로고
    • How some T cells escape tolerance induction
    • Gammon, G., and Sercarz, E. (1989). How some T cells escape tolerance induction. Nature 342, 183-185.
    • (1989) Nature , vol.342 , pp. 183-185
    • Gammon, G.1    Sercarz, E.2
  • 16
    • 0026080797 scopus 로고
    • T cell determinant structure: Cores and determinant envelopes in three mouse major histocompatibility complex haplotypes
    • Gammon, G., Geysen, H.M., Apple, R.J., Pickett, E., Palmer, M., Ametani, A., and Sercarz, E.E. (1991). T cell determinant structure: Cores and determinant envelopes in three mouse major histocompatibility complex haplotypes. J. Exp. Med. 173, 609-617.
    • (1991) J. Exp. Med. , vol.173 , pp. 609-617
    • Gammon, G.1    Geysen, H.M.2    Apple, R.J.3    Pickett, E.4    Palmer, M.5    Ametani, A.6    Sercarz, E.E.7
  • 17
    • 0031562686 scopus 로고    scopus 로고
    • Determinant selection for T-cell tolerance in HEL-transgenic mice: Dissociation between immunogenicity and tolerogenicity
    • Gapin, L., Cabaniols, J.P., Cibotti, R., Ojcius, D.M., Kourilsky, P., and Kanellopoulos, J.M. (1997). Determinant selection for T-cell tolerance in HEL-transgenic mice: Dissociation between immunogenicity and tolerogenicity. Cell. Immunol. 177, 77-85.
    • (1997) Cell. Immunol. , vol.177 , pp. 77-85
    • Gapin, L.1    Cabaniols, J.P.2    Cibotti, R.3    Ojcius, D.M.4    Kourilsky, P.5    Kanellopoulos, J.M.6
  • 18
    • 0020581969 scopus 로고
    • Analysis of true anti-hapten cytotoxic clones in limit dilution microcultures after correction for "anti-self" activity: Precursor frequencies, Ly-2 and Thy-1 phenotype, specificity, and statistical methods
    • Good, M.F., Boyd, A.W., and Nossal, G.J. (1983). Analysis of true anti-hapten cytotoxic clones in limit dilution microcultures after correction for "anti-self" activity: Precursor frequencies, Ly-2 and Thy-1 phenotype, specificity, and statistical methods. J. Immunol. 130, 2046-2055.
    • (1983) J. Immunol. , vol.130 , pp. 2046-2055
    • Good, M.F.1    Boyd, A.W.2    Nossal, G.J.3
  • 20
    • 0032400915 scopus 로고    scopus 로고
    • Isolation and quantitation of a minor determinant of hen egg white lysozyme bound to l-Ak by using peptide-specific immunoaffinity
    • Gugasyan, R., Vidavsky, I., Nelson, C.A., Gross, M.L., and Unanue, E.R. (1998). Isolation and quantitation of a minor determinant of hen egg white lysozyme bound to l-Ak by using peptide-specific immunoaffinity. J. Immunol. 161, 6074-6083.
    • (1998) J. Immunol. , vol.161 , pp. 6074-6083
    • Gugasyan, R.1    Vidavsky, I.2    Nelson, C.A.3    Gross, M.L.4    Unanue, E.R.5
  • 21
    • 0031769696 scopus 로고    scopus 로고
    • An endogenously processed self peptide and the corresponding exogenous peptide bound to the same MHC class II molecule could be distinct ligands for TCR with different kinetic stability
    • Gyotoku, T., Fukui, Y., and Sasazuki, T. (1998). An endogenously processed self peptide and the corresponding exogenous peptide bound to the same MHC class II molecule could be distinct ligands for TCR with different kinetic stability. Eur. J. Immunol. 28, 4050-4061.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 4050-4061
    • Gyotoku, T.1    Fukui, Y.2    Sasazuki, T.3
  • 23
    • 0028298047 scopus 로고
    • Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells
    • Ho, W.Y., Cooke, M.P., Goodnow, C.C., and Davis, M.M. (1994). Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells. J. Exp. Med. 179, 1539-1549.
    • (1994) J. Exp. Med. , vol.179 , pp. 1539-1549
    • Ho, W.Y.1    Cooke, M.P.2    Goodnow, C.C.3    Davis, M.M.4
  • 24
    • 0028935078 scopus 로고
    • Cell surface expression of class II MHC proteins bound by a single peptide
    • Ignatowicz, L., Winslow, G., Bill, J., Kappler, J., and Marrack, P. (1995). Cell surface expression of class II MHC proteins bound by a single peptide. J. Immunol. 154, 3852-3862.
    • (1995) J. Immunol. , vol.154 , pp. 3852-3862
    • Ignatowicz, L.1    Winslow, G.2    Bill, J.3    Kappler, J.4    Marrack, P.5
  • 26
    • 0023894232 scopus 로고
    • Antibody-mediated activation of T cell clones as a method for screening hybridomas producing antibodies to the T cell receptor
    • Kanagawa, O. (1988). Antibody-mediated activation of T cell clones as a method for screening hybridomas producing antibodies to the T cell receptor. J. Immunol. Methods 110, 169-178.
    • (1988) J. Immunol. Methods , vol.110 , pp. 169-178
    • Kanagawa, O.1
  • 28
    • 0027221159 scopus 로고
    • Threshold detection of self-antigen/MHC class II complexes formed in vivo: Constitutive presentation of an immunodominant epitope of hen egg lysozyme (HEL) in HEL-transgenic mice
    • Kanost, D., Basten, A., and McCluskey, J. (1993). Threshold detection of self-antigen/MHC class II complexes formed in vivo: Constitutive presentation of an immunodominant epitope of hen egg lysozyme (HEL) in HEL-transgenic mice. Int. Immunol. 5, 893-902.
    • (1993) Int. Immunol. , vol.5 , pp. 893-902
    • Kanost, D.1    Basten, A.2    McCluskey, J.3
  • 29
    • 0021271337 scopus 로고
    • Secretion of interleukin 2, macrophage-activating factor, interferon, and colony-stimulating factor by alloreactive T lymphocyte clones
    • Kelso, A., and Glasebrook, A.L. (1984). Secretion of interleukin 2, macrophage-activating factor, interferon, and colony-stimulating factor by alloreactive T lymphocyte clones. J. Immunol. 132, 2924-2931.
    • (1984) J. Immunol. , vol.132 , pp. 2924-2931
    • Kelso, A.1    Glasebrook, A.L.2
  • 30
    • 0031458442 scopus 로고    scopus 로고
    • The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells
    • Kimachi, K., Croft, M., and Grey, H.M. (1997). The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells. Eur. J. Immunol. 27, 3310-3317.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3310-3317
    • Kimachi, K.1    Croft, M.2    Grey, H.M.3
  • 31
    • 0027717869 scopus 로고
    • A vector driving the expression of foreign cDNAs in the MHC class ii-positive cells of transgenic mice
    • Kouskoff, V., Fehling, H.J., Lemeur, M., Benoist, C., and Mathis, D. (1993). A vector driving the expression of foreign cDNAs in the MHC class ii-positive cells of transgenic mice. J. Immunol. Methods 166, 287-291.
    • (1993) J. Immunol. Methods , vol.166 , pp. 287-291
    • Kouskoff, V.1    Fehling, H.J.2    Lemeur, M.3    Benoist, C.4    Mathis, D.5
  • 33
    • 0028824098 scopus 로고
    • Low avidity recognition of self-antigen by T cells permits escape from central tolerance
    • Liu, G.Y., Fairchild, P.J., Smith, R.M., Prowle, J.R., Kioussis, D., and Wraith, D.C. (1995). Low avidity recognition of self-antigen by T cells permits escape from central tolerance. Immunity 3, 407-415.
    • (1995) Immunity , vol.3 , pp. 407-415
    • Liu, G.Y.1    Fairchild, P.J.2    Smith, R.M.3    Prowle, J.R.4    Kioussis, D.5    Wraith, D.C.6
  • 34
    • 0027479452 scopus 로고
    • The inability to process a self-peptide allows autoreactive T cells to escape tolerance
    • Mamula, M.J. (1993). The inability to process a self-peptide allows autoreactive T cells to escape tolerance. J. Exp. Med. 177, 567-571.
    • (1993) J. Exp. Med. , vol.177 , pp. 567-571
    • Mamula, M.J.1
  • 35
    • 0024399069 scopus 로고
    • Functional identification of agretopic and epitopic residues within an HBcAg T cell determinant
    • Milich, D.R., Hughes, J.L., Houghten, R., McLachlan, A., and Jones, J.E. (1989). Functional identification of agretopic and epitopic residues within an HBcAg T cell determinant. J. Immunol. 143, 3141-3147.
    • (1989) J. Immunol. , vol.143 , pp. 3141-3147
    • Milich, D.R.1    Hughes, J.L.2    Houghten, R.3    McLachlan, A.4    Jones, J.E.5
  • 36
    • 0025819555 scopus 로고
    • Autoantibody production in hepatitis B e antigen transgenic mice elicited with a self T-cell peptide and inhibited with nonself peptides
    • Milich, D.R., McLachlan, A., Raney, A.K., Houghten, R., Thornton, G.B., Maruyama, T., Hughes, J.L., and Jones, J.E. (1991). Autoantibody production in hepatitis B e antigen transgenic mice elicited with a self T-cell peptide and inhibited with nonself peptides. Proc. Natl. Acad. Sci. USA 88, 4348-4352.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4348-4352
    • Milich, D.R.1    McLachlan, A.2    Raney, A.K.3    Houghten, R.4    Thornton, G.B.5    Maruyama, T.6    Hughes, J.L.7    Jones, J.E.8
  • 37
    • 0027524738 scopus 로고
    • Dominant determinants in hen eggwhite lysozyme correspond to the cryptic determinants within its self-homologue, mouse lysozyme: Implications in shaping of the T cell repertoire and autoimmunity
    • Moudgil, K.D., and Sercarz, E.E. (1993). Dominant determinants in hen eggwhite lysozyme correspond to the cryptic determinants within its self-homologue, mouse lysozyme: Implications in shaping of the T cell repertoire and autoimmunity. J. Exp. Med. 178, 2131-2138.
    • (1993) J. Exp. Med. , vol.178 , pp. 2131-2138
    • Moudgil, K.D.1    Sercarz, E.E.2
  • 38
    • 0026667402 scopus 로고
    • Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule l-Ak
    • Nelson, C.A., Roof, R.W., McCourt, D.W., and Unanue, E.R. (1992). Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule l-Ak. Proc. Natl. Acad. Sci. USA 89, 7380-7383.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7380-7383
    • Nelson, C.A.1    Roof, R.W.2    McCourt, D.W.3    Unanue, E.R.4
  • 39
    • 0030015509 scopus 로고    scopus 로고
    • A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule l-Ak
    • Nelson, C.A., Viner, N.J., Young, S.P., Petzold, S.J., and Unanue, E.R. (1996). A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule l-Ak. J. Immunol. 157, 755-762.
    • (1996) J. Immunol. , vol.157 , pp. 755-762
    • Nelson, C.A.1    Viner, N.J.2    Young, S.P.3    Petzold, S.J.4    Unanue, E.R.5
  • 40
    • 0031030323 scopus 로고    scopus 로고
    • Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules
    • Nelson, C.A., Vidavsky, I., Viner, N.J., Gross, M.L., and Unanue, E.R. (1997). Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules. Proc. Natl. Acad. Sci. USA 94, 628-633.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 628-633
    • Nelson, C.A.1    Vidavsky, I.2    Viner, N.J.3    Gross, M.L.4    Unanue, E.R.5
  • 42
    • 0033559135 scopus 로고    scopus 로고
    • Cutting edge: Negative selection of immature thymocytes by a few peptide-MHC complexes: Differential sensitivity of immature and mature T cells
    • Peterson, D.A., DiPaolo, R.J., Kanagawa, O., and Unanue, E.R. (1999). Cutting edge: Negative selection of immature thymocytes by a few peptide-MHC complexes: Differential sensitivity of immature and mature T cells. J. Immunol. 162, 3117-3120.
    • (1999) J. Immunol. , vol.162 , pp. 3117-3120
    • Peterson, D.A.1    DiPaolo, R.J.2    Kanagawa, O.3    Unanue, E.R.4
  • 43
    • 0025761241 scopus 로고
    • Lower receptor avidity required for thymic clonal deletion than for effector T-cell function
    • Pircher, H., Rohrer, U.H., Moskophidis, D., Zinkernagel, R.M., and Hengartner, H. (1991). Lower receptor avidity required for thymic clonal deletion than for effector T-cell function. Nature 351,482-485.
    • (1991) Nature , vol.351 , pp. 482-485
    • Pircher, H.1    Rohrer, U.H.2    Moskophidis, D.3    Zinkernagel, R.M.4    Hengartner, H.5
  • 44
    • 0031941344 scopus 로고    scopus 로고
    • Avoidance of self-reactivity results in skewed CTL responses to rare components of synthetic immunogens
    • Purcell, A.W., Chen, W., Ede, N.J., Gorman, J.J., Fecondo, J.V., Jackson, D.C., Zhao, Y., and McCluskey, J. (1998). Avoidance of self-reactivity results in skewed CTL responses to rare components of synthetic immunogens. J. Immunol. 160, 1085-1090.
    • (1998) J. Immunol. , vol.160 , pp. 1085-1090
    • Purcell, A.W.1    Chen, W.2    Ede, N.J.3    Gorman, J.J.4    Fecondo, J.V.5    Jackson, D.C.6    Zhao, Y.7    McCluskey, J.8
  • 45
    • 0030833638 scopus 로고    scopus 로고
    • Specific T cell recognition of kinetic isomers in the binding of peptide to class II major histocompatibility complex
    • Rabinowitz, J.D., Tate, K., Lee, C., Beeson, C., and McConnell, H.M. (1997). Specific T cell recognition of kinetic isomers in the binding of peptide to class II major histocompatibility complex. Proc. Natl. Acad. Sci. USA 94, 8702-8707.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8702-8707
    • Rabinowitz, J.D.1    Tate, K.2    Lee, C.3    Beeson, C.4    McConnell, H.M.5
  • 46
    • 0030152129 scopus 로고    scopus 로고
    • Immune responses to self peptides naturally presented by murine class II major histocompatibility complex molecules
    • Rider, B.J., Fraga, E., Yu, Q., and Singh, B. (1996). Immune responses to self peptides naturally presented by murine class II major histocompatibility complex molecules. Mol. Immunol. 33, 625-633.
    • (1996) Mol. Immunol. , vol.33 , pp. 625-633
    • Rider, B.J.1    Fraga, E.2    Yu, Q.3    Singh, B.4
  • 47
    • 0025836774 scopus 로고
    • Fine specificity of cytotoxic T lymphocytes primed in vivo either with virus or synthetic lipopeptide vaccine or primed in vitro with peptide
    • Schild, H., Norda, M., Deres, K., Falk, K., Rotzschke, O., Wiesmuller, K.H., Jung, G., and Rammensee, H.G. (1991). Fine specificity of cytotoxic T lymphocytes primed in vivo either with virus or synthetic lipopeptide vaccine or primed in vitro with peptide. J. Exp. Med. 174, 1665-1668.
    • (1991) J. Exp. Med. , vol.174 , pp. 1665-1668
    • Schild, H.1    Norda, M.2    Deres, K.3    Falk, K.4    Rotzschke, O.5    Wiesmuller, K.H.6    Jung, G.7    Rammensee, H.G.8
  • 48
    • 0028294682 scopus 로고
    • Positive and negative thymocyte selection induced by different concentrations of a single peptide
    • Sebzda, E., Wallace, V.A., Mayer, J., Yeung, R.S., Mak, T.W., and Ohashi, P.S. (1994). Positive and negative thymocyte selection induced by different concentrations of a single peptide. Science 263, 1615-1618.
    • (1994) Science , vol.263 , pp. 1615-1618
    • Sebzda, E.1    Wallace, V.A.2    Mayer, J.3    Yeung, R.S.4    Mak, T.W.5    Ohashi, P.S.6
  • 49
    • 0031059755 scopus 로고    scopus 로고
    • A major T cell determinant from the influenza virus hemagglutinin (HA) can be a cryptic self peptide in HA transgenic mice
    • Shin, F.F., Cerasoli, D.M., and Caton, A.J. (1997). A major T cell determinant from the influenza virus hemagglutinin (HA) can be a cryptic self peptide in HA transgenic mice. Int. Immunol. 9, 249-261.
    • (1997) Int. Immunol. , vol.9 , pp. 249-261
    • Shin, F.F.1    Cerasoli, D.M.2    Caton, A.J.3
  • 50
    • 0032526853 scopus 로고    scopus 로고
    • Endogenous myelin basic protein inactivates the high avidity T cell repertoire
    • Targoni, O.S., and Lehmann, P.V. (1998). Endogenous myelin basic protein inactivates the high avidity T cell repertoire. J. Exp. Med. 187, 2055-2063.
    • (1998) J. Exp. Med. , vol.187 , pp. 2055-2063
    • Targoni, O.S.1    Lehmann, P.V.2
  • 51
    • 0033032124 scopus 로고    scopus 로고
    • Inhibition of thymocyte positive selection by natural MHC: Peptide ligands
    • Tourne, S., Kouskoff, V., Ho, W., Davis, M., Benoist, C., and Mathis, D. (1999). Inhibition of thymocyte positive selection by natural MHC: Peptide ligands. Eur. J. Immunol. 29, 394-402.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 394-402
    • Tourne, S.1    Kouskoff, V.2    Ho, W.3    Davis, M.4    Benoist, C.5    Mathis, D.6
  • 52
    • 0026551703 scopus 로고
    • In vivo and in vitro clonal deletion of double-positive thymocytes
    • Vasquez, N.J., Kaye, J., and Hedrick, S.M. (1992). In vivo and in vitro clonal deletion of double-positive thymocytes. J. Exp. Med. 175, 1307-1316.
    • (1992) J. Exp. Med. , vol.175 , pp. 1307-1316
    • Vasquez, N.J.1    Kaye, J.2    Hedrick, S.M.3
  • 53
    • 0029937756 scopus 로고    scopus 로고
    • Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing
    • Viner, N.J., Nelson, C.A., Deck, B., and Unanue, E.R. (1996). Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing. J. Immunol. 156, 2365-2368.
    • (1996) J. Immunol. , vol.156 , pp. 2365-2368
    • Viner, N.J.1    Nelson, C.A.2    Deck, B.3    Unanue, E.R.4
  • 54
    • 0032167433 scopus 로고    scopus 로고
    • Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice
    • [published erratum appears in J. Clin. Invest. (1998). 102, following 1463]
    • Wen, L., Wong, F.S., Burkly, L, Altieri, M., Mamalaki, C., Kioussis, D., Flavell, R.A., and Sherwin, R.S. (1998). Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice [published erratum appears in J. Clin. Invest. (1998). 102, following 1463]. J. Clin. Invest. 102, 947-957.
    • (1998) J. Clin. Invest. , vol.102 , pp. 947-957
    • Wen, L.1    Wong, F.S.2    Burkly, L.3    Altieri, M.4    Mamalaki, C.5    Kioussis, D.6    Flavell, R.A.7    Sherwin, R.S.8
  • 55
    • 0025095655 scopus 로고
    • Ligand thresholds at different stages of T cell development
    • Yagi, J., and Janeway, C.A., Jr. (1990). Ligand thresholds at different stages of T cell development. Int. Immunol. 2, 83-89.
    • (1990) Int. Immunol. , vol.2 , pp. 83-89
    • Yagi, J.1    Janeway C.A., Jr.2
  • 56
    • 0027180397 scopus 로고
    • Hen egg-white lysozyme-specific T cells elicited in hen egg-white lysozyme-transgenic mice retain an imprint of self-tolerance
    • Yule, T.D., Basten, A., and Allen, P.M. (1993). Hen egg-white lysozyme-specific T cells elicited in hen egg-white lysozyme-transgenic mice retain an imprint of self-tolerance. J. Immunol. 151, 3057-3069.
    • (1993) J. Immunol. , vol.151 , pp. 3057-3069
    • Yule, T.D.1    Basten, A.2    Allen, P.M.3


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