Structural requirement of the calcium-channel subunit α2δ for gabapentin binding

Biochemical Journal

Volumn 342, Issue 2, 1999, Pages 313-320

  Wang, Minghan ^a   Offord, James ^a   Oxender, Dale L ^a   Su, Ti Zhi ^a  

^a PFIZER INC   (United States)

Author keywords

Anticonvulsant; Ca2+ channel; Co transfection; Disulphide bond; GABA

Indexed keywords

ANTICONVULSIVE AGENT; ARGININE; BRAIN PROTEIN; CALCIUM CHANNEL; GABAPENTIN; MEMBRANE PROTEIN; MUTANT PROTEIN; PROTEIN SUBUNIT;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; DNA TRANSFECTION; DRUG PROTEIN BINDING; EXPRESSION VECTOR; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SWINE;

ACETIC ACIDS; AMINES; AMINO ACID SEQUENCE; ANIMALS; ANTICONVULSANTS; BASE SEQUENCE; BINDING SITES; CALCIUM CHANNELS; COS CELLS; CYCLOHEXANECARBOXYLIC ACIDS; DISULFIDES; DNA PRIMERS; GAMMA-AMINOBUTYRIC ACID; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE MAPPING; POINT MUTATION; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; SEQUENCE DELETION; SWINE; TRANSFECTION;

EID: 0033198905     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3420313     Document Type: Article

References (37)

1. Catterall, W. A. (1995) Annu. Rev. Biochem. 64, 493-531
2. Hosey, M. M. and Lazdunski, M. (1988) J. Membr. Biol. 104, 81-105
3. Miller, R. (1992) J. Biol. Chem. 267, 1403-1406
4. Smith, S. J. and Augustine, G. J. (1988) Trends Neurosci. 11, 458-464
5. Witcher, D. R., De Waard, M., Sakamoto, J., Franzini-Armstrong, C., Pragnell, M., Kahl, S. D. and Campbell, K. P. (1993) Science 261, 486-489
6. Perez-Reyes, E., Kim, H. S., Lacerda, A. E., Horne, W., Xiangyang, W., Rampe, D., Campbell, K. P., Brown, A. M. and Birnbaumer, L. (1989) Nature (London) 340, 233-236
7. Varadi, G., Lory, P., Schultz, D., Varadi, M. and Schwartz, A. (1991) Nature (London) 352, 159-162
8. Brust, P. F., Simerson, S., McCue, A. F., Deal, C. R., Schoonmaker, S., Williams, M., Velicelebi, G., Johnson, E. C., Harpold, M. M. and Ellis, S. B. (1993) Neuropharmacology 32, 1089-1102
9. Flucher, B. E., Phillips, J. L. and Powell, J. A. (1991) J. Cell Biol. 115, 1345-1356
10. Williams, M. E., Brust, P. F., Feldman, D. H., Patthi, S., Simerson, S., Maroufi, A., McCue, A. F., Velicelebi, G., Ellis, S. B. and Harpold, M. M. (1992) Science 257, 389-395
11. Leung, A. T., Imagawa, T. and Campbell, K. P. (1987) J. Biol. Chem. 262, 7943-7946
12. Gurnett, C. A., De Waard, M. and Campbell, K. P. (1996) Neuron 16, 431-440
13. Ellis, S. B., Williams, M. E., Ways, N. R., Brenner, R., Sharp, A. H., Leung, A. T., Campbell, K. P., McKenna, E., Koch, W. J., Hui, A., Schwartz, A. and Harpold, M. M. (1988) Science 241, 1661-1664
14. Takahashi, M., Seagar, M., Jones, J., Reber, B. and Catterall, W. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 5478-5482
15. Kim, H.-L. Kim, H., Lee, P., King, R. G. and Chim, H. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 3251-3255
16. Angelotti, T. and Hofmann, F. (1996) FEBS Lett. 397, 331-337
17. Brickley, K., Campbell, V., Berrow, N., Leach, R., Norman, R. I., Wray, D., Dolphin, A. C. and Baldwin, S. A. (1995) FEBS Lett. 364, 129-133
18. Wiser, O., Trus, M., Tobi, D., Halevi, S., Giladi, E. and Atlas, D. (1996) FEBS Lett. 379, 15-20
19. Gilad, B., Shenkar, N., Halevi, S., Trus, M. and Atlas, D. (1995) Neurosci. Lett. 193, 157-160
20. Chadwick, D. (1992) in Recent Advances in Epilepsy, Volume 5 (Pedley, T. A. and Meldrum, B. S., eds.), pp. 211-221, Churchill-Livingstone, Edinburgh
21. Stewart, B. H., Kugler, A. R., Thompson, P. R. and Bockbader, H. N. (1993) Pharmacol. Res. 10, 276-281
22. Su, T.-Z., Lunney, E., Campbell, G. and Oxender, D. L. (1995) J. Neurochem. 64, 2125-2131
23. Taylor, C. P., Gee, N. S., Su, T.-Z., Kocsis, J., Welty, D., Brown, J. P., Davis, J. D., Boden, P. and Singh, L. (1998) Epilepsy Res. 29, 233-249
24. Schmidt, B. (1989) in Antiepileptic Drugs, 3rd edn. (Levy, R., ed.), pp. 925-935, Raven Press, New York
25. Goldlust, A., Su, T.-Z., Welty, D. F., Taylor, C. P. and Oxender, D. L. (1995) Epilepsy Res. 22, 1-11
26. Field, M. J., Oles, R. J., Lewis, A. S., McCleary, S., Hughes, J. and Singh, L. (1997) Br. J. Pharmacol. 121, 1513-1522
27. Singh, L., Field, M. J., Ferris, P., Hunter, J. C., Oles, R. J., Williams, R. G. and Woodruff, G. N. (1996) Psychopharmacology 127, 1-9
28. Gurney, M. E., Cutting, F. B., Zhai, P., Doble, A., Taylor, C. P., Andrus, P. K. and Hall, E. D. (1996) Ann. Neurol. 39, 147-157
29. Gee, N. S., Brown, J. P., Dissanayake, V. U. K., Offord, J., Thurlow, R. and Woodruff, G. N. (1996) J. Biol. Chem. 271, 5768-5776
30. Jay, S. D., Sharp, A. H., Kahl, S. D., Vedvick, T. S., Harpold, M. M. and Campbell, K. P. (1991) J. Biol. Chem. 266, 3287-3293
31. Felix, R., Gurnett C. A., De Waard, M. and Campbell, K. P. (1997) J. Neurosci. 17, 6884-6891
32. Reimann, W. (1983) Eur. J. Pharmacol. 94, 341-344
33. Schlicker, E., Reimann, W. and Gothert, M. (1985) Drug Res. 35, 1347-1349
34. Rock, D. M., Kelly, K. M. and Macdonald, R. L. (1993) Epilepsy Res. 16, 89-98
35. Stefani, A., Spadoni, F. and Bernadi, G. (1998) Neuropharmacology 37, 83-91
36. Fletcher, C. F., Lutz, C. M., O'Sullivan, T. N., Shaughnessy, Jr., J., Hawkes, R., Frankel, W. N., Copeland, N. G. and Jenkins, N. A. (1996) Cell 87, 607-617
37. Burgess, D. L., Jones, J. M., Meisler, M. H. and Noebels, J. L. (1997) Cell 88, 385-392