메뉴 건너뛰기




Volumn 15, Issue 5, 1999, Pages 911-918

The effect of rapeseed oil uptake on the production of erythromycin and triketide lactone by Saccharopolyspora erythraea

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC PRODUCTION; CULTURE MEDIUM; ERYTHROMYCIN; FERMENTATION; FUNGUS METABOLISM; GAS CHROMATOGRAPHY; TRIKETIDE LACTONE;

EID: 0033198745     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp990099h     Document Type: Article
Times cited : (13)

References (56)
  • 1
    • 0029670331 scopus 로고    scopus 로고
    • Engineered biosynthesis of novel polyketides: Properties of the whiE aromatase/cyclase
    • Alvarez, M. A.; Fu, H.; Khosla, C.; Hopwood, D. A.; Bailey, J. E. Engineered biosynthesis of novel polyketides: properties of the whiE aromatase/cyclase. Nature Biotechnol. 1996, 14, 335-338.
    • (1996) Nature Biotechnol. , vol.14 , pp. 335-338
    • Alvarez, M.A.1    Fu, H.2    Khosla, C.3    Hopwood, D.A.4    Bailey, J.E.5
  • 2
    • 0026416683 scopus 로고
    • Plasmid presence changes the relative levels of many host cell proteins and ribosome components in recombinant Escherichia coli
    • Birnbaum, S.; Bailey, J. E. Plasmid presence changes the relative levels of many host cell proteins and ribosome components in recombinant Escherichia coli. Biotechnol. Bioeng. 1990, 37, 736-745.
    • (1990) Biotechnol. Bioeng. , vol.37 , pp. 736-745
    • Birnbaum, S.1    Bailey, J.E.2
  • 3
    • 0000328711 scopus 로고
    • Growth, product formation and fermentation tehnology
    • Goodfellow, M., Williams, S. T., Mordarski, M., Eds.; Academic Press: London, U.K.
    • Bushell, M. E. Growth, product formation and fermentation tehnology. In: Actoinomycetes in biotechnology; Goodfellow, M., Williams, S. T., Mordarski, M., Eds.; Academic Press: London, U.K., 1988; pp 185-218.
    • (1988) Actoinomycetes in Biotechnology , pp. 185-218
    • Bushell, M.E.1
  • 4
    • 0031049494 scopus 로고    scopus 로고
    • A physiological model for control of erythromycin production in batch and cyclic fed batch culture
    • Bushell, M. E.; Smith, J.; Lynch, C. A physiological model for control of erythromycin production in batch and cyclic fed batch culture. Microbiology 1997, 143, 475-480.
    • (1997) Microbiology , vol.143 , pp. 475-480
    • Bushell, M.E.1    Smith, J.2    Lynch, C.3
  • 6
    • 0026013204 scopus 로고
    • The effect of dissolved oxygen and aeration rate on antibiotic production of Streptomyces fradiae
    • Chen, H. C.; Wilde, F. The effect of dissolved oxygen and aeration rate on antibiotic production of Streptomyces fradiae. Biotechnol. Bioeng. 1991, 37, 591-595.
    • (1991) Biotechnol. Bioeng. , vol.37 , pp. 591-595
    • Chen, H.C.1    Wilde, F.2
  • 8
    • 0029954065 scopus 로고    scopus 로고
    • Effect of nitrogen sources on the regulation of extracellular lipase production in Acinetobacter calcoaceticus strains
    • Cordenons, A.; Gonzalez, R.; Kok, R.; Hellingwerf, K. J.; Nudel, C. Effect of nitrogen sources on the regulation of extracellular lipase production in Acinetobacter calcoaceticus strains. Biotechnol. Lett. 1996, 18, 633-638.
    • (1996) Biotechnol. Lett. , vol.18 , pp. 633-638
    • Cordenons, A.1    Gonzalez, R.2    Kok, R.3    Hellingwerf, K.J.4    Nudel, C.5
  • 9
    • 0029027352 scopus 로고
    • Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage
    • Cortes, J.; Wiesmann, K. E. H.; Roberts, G. A.; Brown, M. J. B.; Staunton, J.; Leadlay, P. F. Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage. Science 1995, 268, 1487-1489.
    • (1995) Science , vol.268 , pp. 1487-1489
    • Cortes, J.1    Wiesmann, K.E.H.2    Roberts, G.A.3    Brown, M.J.B.4    Staunton, J.5    Leadlay, P.F.6
  • 10
    • 14744275430 scopus 로고
    • Heritable damage to yeast caused by transformation
    • Danhash, N.; Gardner, D. C. J.; Oliver, S. G. Heritable damage to yeast caused by transformation. Bio/Technology 1991, 9, 179-182.
    • (1991) Bio/Technology , vol.9 , pp. 179-182
    • Danhash, N.1    Gardner, D.C.J.2    Oliver, S.G.3
  • 11
    • 0020469149 scopus 로고
    • Transient repression of antibiotic formation in Streptomyces erythreus
    • Escalante, L.; Lopez, H.; Mateos, R. C.; Lara, F.; Sanchez, S. Transient repression of antibiotic formation in Streptomyces erythreus. J. Gen. Microbiol. 1982, 128, 2011-2015.
    • (1982) J. Gen. Microbiol. , vol.128 , pp. 2011-2015
    • Escalante, L.1    Lopez, H.2    Mateos, R.C.3    Lara, F.4    Sanchez, S.5
  • 13
    • 0024952578 scopus 로고
    • Ammonium assimilating enzymes and erythromycin formation in Saccharopolyspora erythraea
    • Flores, M. E.; Sanchez, S. Ammonium assimilating enzymes and erythromycin formation in Saccharopolyspora erythraea, J. Gen. Microbiol. 1989, 35, 203-211.
    • (1989) J. Gen. Microbiol. , vol.35 , pp. 203-211
    • Flores, M.E.1    Sanchez, S.2
  • 14
    • 0022110461 scopus 로고
    • Capillary GC of triglycerides in fats and oils using a high-temperature phenylmethylsilicone stationary phase
    • Geeraert, E.; Sandra, P. Capillary GC of triglycerides in fats and oils using a high-temperature phenylmethylsilicone stationary phase. J. High Resolut. Chromatogr. Chromatogr. Commun. 1985, 8, 415-422.
    • (1985) J. High Resolut. Chromatogr. Chromatogr. Commun. , vol.8 , pp. 415-422
    • Geeraert, E.1    Sandra, P.2
  • 15
    • 0031936732 scopus 로고    scopus 로고
    • A rapid and simplified extraction method of erythromycin from fermentation broth with bond elut C18 cartridge for analysis by HPLC
    • Heydarian, M. S.; Ison, A. P.; Mirjalili, N. A rapid and simplified extraction method of erythromycin from fermentation broth with bond elut C18 cartridge for analysis by HPLC. Biotechnol. Tech. 1998, 12, 55-60.
    • (1998) Biotechnol. Tech. , vol.12 , pp. 55-60
    • Heydarian, M.S.1    Ison, A.P.2    Mirjalili, N.3
  • 16
    • 0032858590 scopus 로고    scopus 로고
    • Effect of shear on morphology and erythromycin production in Saccharopolyspora erythraea culture
    • Heydarian, M. S.; Mirjalili N.; Ison, A. P. Effect of shear on morphology and erythromycin production in Saccharopolyspora erythraea culture. Bioprocess Eng. 1999, 21, 31-39.
    • (1999) Bioprocess Eng. , vol.21 , pp. 31-39
    • Heydarian, M.S.1    Mirjalili, N.2    Ison, A.P.3
  • 17
    • 0026003358 scopus 로고
    • Positive selection of antibiotic producing soil isolates
    • Huck, T. A.; Proter, N.; Bushell, M. E. Positive selection of antibiotic producing soil isolates. J. Gen. Microbiol. 1991, 137, 2321-2329.
    • (1991) J. Gen. Microbiol. , vol.137 , pp. 2321-2329
    • Huck, T.A.1    Proter, N.2    Bushell, M.E.3
  • 18
    • 0027932534 scopus 로고
    • Engineered biosynthesis of a complete macrolactone in a heterologous host
    • Kao, C. M.; Katz, L.; Khosla, C. Engineered biosynthesis of a complete macrolactone in a heterologous host. Science 1994, 265, 509-512.
    • (1994) Science , vol.265 , pp. 509-512
    • Kao, C.M.1    Katz, L.2    Khosla, C.3
  • 20
    • 0030754550 scopus 로고    scopus 로고
    • Effect of soybean oil and glucose on sophorose lipid fermentation by Torulopsis bombicola in continuous culture
    • Kim, S. Y.; Oh, D. K.; Lee, K H.; Kim, J. H. Effect of soybean oil and glucose on sophorose lipid fermentation by Torulopsis bombicola in continuous culture. Appl. Microbiol. Biotechnol. 1997, 52, 23-26.
    • (1997) Appl. Microbiol. Biotechnol. , vol.52 , pp. 23-26
    • Kim, S.Y.1    Oh, D.K.2    Lee, K.H.3    Kim, J.H.4
  • 21
    • 0002385458 scopus 로고
    • Dissipation of energy in the locally isotropic turbulence
    • Kolmogorov, A. W. Dissipation of energy in the locally isotropic turbulence. Com. Rend. Acad. Sci. (U.S.S.R.) 1941, 32, 16-19.
    • (1941) Com. Rend. Acad. Sci. (U.S.S.R.) , vol.32 , pp. 16-19
    • Kolmogorov, A.W.1
  • 22
    • 0344507413 scopus 로고    scopus 로고
    • The effect of agitation rate on lipid utilisation and clavulanic acid production in Streptomyces clavuligerus
    • Large, K. P.; Ison, A. P.; Williams, D. J. The effect of agitation rate on lipid utilisation and clavulanic acid production in Streptomyces clavuligerus. J. Biotechnol. 1998, 63, 111-119.
    • (1998) J. Biotechnol. , vol.63 , pp. 111-119
    • Large, K.P.1    Ison, A.P.2    Williams, D.J.3
  • 25
    • 0030037544 scopus 로고    scopus 로고
    • Production of clavulanic acid and cephamycin C by Streptomyces clavuligerus in palm oil medium
    • Lee, P. C.; Ho, C. C. Production of clavulanic acid and cephamycin C by Streptomyces clavuligerus in palm oil medium. World J. Microbiol. Biotechnol. 1996, 12, 73-75.
    • (1996) World J. Microbiol. Biotechnol. , vol.12 , pp. 73-75
    • Lee, P.C.1    Ho, C.C.2
  • 26
    • 0024503110 scopus 로고
    • The kinetics and mechanism of shear inactivation of lipase from Candida cylindracea
    • Lee, Y. K.; Choo, C. L. The kinetics and mechanism of shear inactivation of lipase from Candida cylindracea. Biotechnol. Bioeng. 1989, 33, 183-190.
    • (1989) Biotechnol. Bioeng. , vol.33 , pp. 183-190
    • Lee, Y.K.1    Choo, C.L.2
  • 27
    • 0031549639 scopus 로고    scopus 로고
    • Improved oxygen transfer in cultures of Nocardia lactamdurans maintains the cephamycin biosynthesis proteins for prolonged time and enhances the conversion of deacetylcephalosporin into cephamycin C
    • Leitao, A L.; Enguita, F. J.; Martin, J. F. Improved oxygen transfer in cultures of Nocardia lactamdurans maintains the cephamycin biosynthesis proteins for prolonged time and enhances the conversion of deacetylcephalosporin into cephamycin C. J. Biotechnol. 1997, 58, 39-50.
    • (1997) J. Biotechnol. , vol.58 , pp. 39-50
    • Leitao, A.L.1    Enguita, F.J.2    Martin, J.F.3
  • 28
    • 0022548964 scopus 로고
    • Direct transesterification of all classes of lipids in a one-step reaction
    • Lepage, M.; Roy, C. Direct transesterification of all classes of lipids in a one-step reaction. J. Lipid Res. 1986, 27, 114-120.
    • (1986) J. Lipid Res. , vol.27 , pp. 114-120
    • Lepage, M.1    Roy, C.2
  • 29
    • 0030294959 scopus 로고    scopus 로고
    • Studies on localisation and regulation of lipase production by Aspergillus niger
    • Maoris, J. B.; Kourentzi, E.; Hatzinikolaou, D. G. Studies on localisation and regulation of lipase production by Aspergillus niger. Process Biochem. 1996, 31, 807-812.
    • (1996) Process Biochem. , vol.31 , pp. 807-812
    • Maoris, J.B.1    Kourentzi, E.2    Hatzinikolaou, D.G.3
  • 31
    • 0029965543 scopus 로고    scopus 로고
    • Some factors affecting lipase production by yeasts and filamentous fungi
    • Marek, A.; Bednarski, W. Some factors affecting lipase production by yeasts and filamentous fungi. Biotechnol. Lett. 1996, 18, 1155-1160.
    • (1996) Biotechnol. Lett. , vol.18 , pp. 1155-1160
    • Marek, A.1    Bednarski, W.2
  • 32
    • 0032498205 scopus 로고    scopus 로고
    • Engineering broader specificity into an antibiotic-producing polyketide synthase
    • Marsden, A. F. A.; Wilkinson, B.; Cortes, J.; Staunton, J.; Leadlay, P. F. Engineering broader specificity into an antibiotic-producing polyketide synthase. Science 1998, 279, 199-202.
    • (1998) Science , vol.279 , pp. 199-202
    • Marsden, A.F.A.1    Wilkinson, B.2    Cortes, J.3    Staunton, J.4    Leadlay, P.F.5
  • 33
    • 0019292120 scopus 로고
    • Control of antibiotic biosynthesis
    • Martin, J.; Demain, A. Control of antibiotic biosynthesis. Microbiol. Rev. 1980, 44, 230-251.
    • (1980) Microbiol. Rev. , vol.44 , pp. 230-251
    • Martin, J.1    Demain, A.2
  • 34
    • 0014056841 scopus 로고
    • Studies on the biosynthesis of erythromycins. II: Isolation and structure of a biosynthetic intermediate, 6-Deoxyerythronolide B
    • Martin, J. R.; Rosenbrook, W. Studies on the biosynthesis of erythromycins. II: Isolation and structure of a biosynthetic intermediate, 6-Deoxyerythronolide B. Biochemistry 1967, 6, 435-440.
    • (1967) Biochemistry , vol.6 , pp. 435-440
    • Martin, J.R.1    Rosenbrook, W.2
  • 35
    • 0029064652 scopus 로고
    • Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits
    • McDaniel, R.; Ebert-Khosla, S.; Hopwood, D. A.; Khosla, C. Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits. Nature 1995, 375, 549-554.
    • (1995) Nature , vol.375 , pp. 549-554
    • McDaniel, R.1    Ebert-Khosla, S.2    Hopwood, D.A.3    Khosla, C.4
  • 36
    • 1842406060 scopus 로고    scopus 로고
    • Application of mineral support on cephamycin C production in culture using soybean oil as the sole carbon source
    • Mitsuru, I.; Park, Y. S.; Kosakai, Y.; Okabe, M. Application of mineral support on cephamycin C production in culture using soybean oil as the sole carbon source. Biotechnol. Bioeng. 1997, 53, 207-213.
    • (1997) Biotechnol. Bioeng. , vol.53 , pp. 207-213
    • Mitsuru, I.1    Park, Y.S.2    Kosakai, Y.3    Okabe, M.4
  • 37
    • 0022999678 scopus 로고
    • Enzymes of secondary metabolism and the biosynthesis of macrolide antibiotics
    • Neusil, J.; Hostalek, Z. Enzymes of secondary metabolism and the biosynthesis of macrolide antibiotics. Folia Microbiol. 1986, 31, 402-421.
    • (1986) Folia Microbiol. , vol.31 , pp. 402-421
    • Neusil, J.1    Hostalek, Z.2
  • 38
    • 0029035406 scopus 로고
    • Comparison of neomycin production from Streptomyces fradiae cultivation using soybean oil as the sole carbon source in an air lift bioreactor and a stirred reactor
    • Ohta, N.; Park, Y. S.; Yahiro, K.; Okabe, M. Comparison of neomycin production from Streptomyces fradiae cultivation using soybean oil as the sole carbon source in an air lift bioreactor and a stirred reactor. J. Ferment. Bioeng. 1995, 79, 443-448.
    • (1995) J. Ferment. Bioeng. , vol.79 , pp. 443-448
    • Ohta, N.1    Park, Y.S.2    Yahiro, K.3    Okabe, M.4
  • 39
    • 0001079703 scopus 로고
    • Efficient utilisation of fatty oils as energy source in penicillin fermentation
    • Pan, S. C.; Bonanno S.; Wagman G. H. Efficient utilisation of fatty oils as energy source in penicillin fermentation. Appl. Microbiol. 1959, 7, 176-180.
    • (1959) Appl. Microbiol. , vol.7 , pp. 176-180
    • Pan, S.C.1    Bonanno, S.2    Wagman, G.H.3
  • 40
    • 0028267508 scopus 로고
    • Enhancement of cephamycin C production using soybean oil as the sole carbon source
    • Park, Y. S.; Momose, I.; Tsunoda; Okabe, M. Enhancement of cephamycin C production using soybean oil as the sole carbon source. Appl. Microbiol. Biotechnol. 1994, 40, 773-779.
    • (1994) Appl. Microbiol. Biotechnol. , vol.40 , pp. 773-779
    • Park, Y.S.1    Momose, I.2    Okabe, M.3
  • 41
    • 0346539558 scopus 로고    scopus 로고
    • Enhancement of growth and antibiotic titre in Cephalosporium acremonium induced by sesame oil
    • Paul, S.; Bezbaruah, R. L.; Prakasham, R. S.; Roy, M. K.; Ghosh, A. C. Enhancement of growth and antibiotic titre in Cephalosporium acremonium induced by sesame oil. Folia Microbiol. 1997, 42, 211-213.
    • (1997) Folia Microbiol. , vol.42 , pp. 211-213
    • Paul, S.1    Bezbaruah, R.L.2    Prakasham, R.S.3    Roy, M.K.4    Ghosh, A.C.5
  • 42
    • 0345686919 scopus 로고
    • Studies on the utlisation of lipids by Streptomyces griseus
    • Pelman D.; Wagman, G. H. Studies on the utlisation of lipids by Streptomyces griseus. J. Bacteriol. 1952, 63, 253-262.
    • (1952) J. Bacteriol. , vol.63 , pp. 253-262
    • Pelman, D.1    Wagman, G.H.2
  • 43
    • 0028933907 scopus 로고
    • Simultaneous determination of glycerol, and mono-, di-and triglycerides in vegetable oil methyl esters by capillary gas chromatography
    • Plank, C.; Lorbeer, E. Simultaneous determination of glycerol, and mono-, di-and triglycerides in vegetable oil methyl esters by capillary gas chromatography. J. Chromatogr., A 1995, 697, 461-468.
    • (1995) J. Chromatogr., A , vol.697 , pp. 461-468
    • Plank, C.1    Lorbeer, E.2
  • 44
    • 0028264897 scopus 로고
    • Effect of nutritional factors on lipase biosynthesis by Aspergillus niger
    • Pokorny, D.; Friedrich, D.; Cimerman, A. Effect of nutritional factors on lipase biosynthesis by Aspergillus niger. Biotechnol. Lett. 1994, 16, 363-366.
    • (1994) Biotechnol. Lett. , vol.16 , pp. 363-366
    • Pokorny, D.1    Friedrich, D.2    Cimerman, A.3
  • 45
    • 0028097878 scopus 로고
    • Ammonium regulation in Saccharopolyspora erythraea. I: Growth and antibiotic production
    • Potvin, J.; Peringer, P. Ammonium regulation in Saccharopolyspora erythraea. I: Growth and antibiotic production. Biotechnol. Lett. 1994, 16, 63-68.
    • (1994) Biotechnol. Lett. , vol.16 , pp. 63-68
    • Potvin, J.1    Peringer, P.2
  • 47
    • 0030298021 scopus 로고    scopus 로고
    • The relation between biomass concentration determined by a capacitance-based probe, rheology and morphology of Saccharopolyspora erythraea
    • Sarra, M.; Ison, A. P.; Lilly, M. D. The relation between biomass concentration determined by a capacitance-based probe, rheology and morphology of Saccharopolyspora erythraea. J. Biotechnol. 1996, 51, 157-165.
    • (1996) J. Biotechnol. , vol.51 , pp. 157-165
    • Sarra, M.1    Ison, A.P.2    Lilly, M.D.3
  • 48
    • 0028192118 scopus 로고
    • Instability in electrophoretic karyotype of brewing yeasts
    • Sato, M.; Watari, J.; Sahara, H.; Koshino, S. Instability in electrophoretic karyotype of brewing yeasts. J. Am. Soc. Brew. Chem. 1994, 52, 148-151.
    • (1994) J. Am. Soc. Brew. Chem. , vol.52 , pp. 148-151
    • Sato, M.1    Watari, J.2    Sahara, H.3    Koshino, S.4
  • 49
    • 0028282156 scopus 로고
    • Changes in cellular fatty acid composition of Cephalosporium acremonium during cephalosporin C production
    • Sohn, Y. S.; Lee, K. C.; Koh, Y. H.; Gill G. H. Changes in cellular fatty acid composition of Cephalosporium acremonium during cephalosporin C production. Appl. Environ. Microbiol. 1994, 60, 947-952.
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 947-952
    • Sohn, Y.S.1    Lee, K.C.2    Koh, Y.H.3    Gill, G.H.4
  • 51
    • 0025936455 scopus 로고
    • The extraordinary enzymes involved in erythromycin biosynthesis
    • Staunton, J. The extraordinary enzymes involved in erythromycin biosynthesis. Angew. Chem., Int. Ed. Engl. 1991, 30, 1302-1306.
    • (1991) Angew. Chem., Int. Ed. Engl. , vol.30 , pp. 1302-1306
    • Staunton, J.1
  • 52
    • 0011997182 scopus 로고
    • The application of oils and fats in antibiotic processes
    • Stowell, J. D., Ed.; IRL Press: Oxford, U.K.
    • Stowell, J. D. The application of oils and fats in antibiotic processes. In Carbon substrates in biotechnology; Stowell, J. D., Ed.; IRL Press: Oxford, U.K., 1987; pp 139-159.
    • (1987) Carbon Substrates in Biotechnology , pp. 139-159
    • Stowell, J.D.1
  • 53
    • 0029125339 scopus 로고
    • Malonyl coenzyme A: Acyl carrier protein acyltransferase of Streptomyces glaucescens: A possible link between fatty acid and polyketide biosynthesis
    • Summers, R. G.; Ali, A.; Shen, B.; Wessel, W. A.; Hutchinson, C. R. Malonyl coenzyme A: acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis. Biochemistry 1995, 34, 9389-9402.
    • (1995) Biochemistry , vol.34 , pp. 9389-9402
    • Summers, R.G.1    Ali, A.2    Shen, B.3    Wessel, W.A.4    Hutchinson, C.R.5
  • 54
    • 0025945664 scopus 로고
    • Growth and production of penicillin in Penicillium chrysogenum with palm oil and its various fractions as carbon sources
    • Tan, I. K.; Ho, C. C. Growth and production of penicillin in Penicillium chrysogenum with palm oil and its various fractions as carbon sources. Appl. Microbiol. Biotechnol. 1991, 36, 163-166.
    • (1991) Appl. Microbiol. Biotechnol. , vol.36 , pp. 163-166
    • Tan, I.K.1    Ho, C.C.2
  • 55
    • 0023616194 scopus 로고
    • Relation between growth rate and erythromycin production in Streptomyces erythraeus
    • Trilli, A.; Crossley, M. V.; Kontakou, M. Relation between growth rate and erythromycin production in Streptomyces erythraeus. Biotechnol. Lett. 1987, 9, 765-770.
    • (1987) Biotechnol. Lett. , vol.9 , pp. 765-770
    • Trilli, A.1    Crossley, M.V.2    Kontakou, M.3
  • 56
    • 0024144974 scopus 로고
    • Efficiency of natural oils as antifoaming agents in bioprocesses
    • Vardar-Sukan, F. Efficiency of natural oils as antifoaming agents in bioprocesses, J. Chem. Technol. Biotechnol. 1988, 43, 39-47.
    • (1988) J. Chem. Technol. Biotechnol. , vol.43 , pp. 39-47
    • Vardar-Sukan, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.