Inhibition of Shigella flexneri-induced transepithelial migration of polymorphonuclear leucocytes by cadaverine

Cellular Microbiology

Volumn 1, Issue 2, 1999, Pages 143-155

  McCormick, Beth A ^a,b   Fernandez, M Isabel ^a,b   Siber, Andrew M ^a   Maurelli, Anthony T ^c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CADAVERINE; CARBOXYLYASE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; INTERLEUKIN 8; LYSINE; LYSINE DECARBOXYLASE; MEMBRANE PROTEIN; PHOSPHOPROTEIN; ZONULA OCCLUDENS 1 PROTEIN; ZONULA OCCLUDENS-1 PROTEIN;

ARTICLE; CELL LINE; CELL MOTION; CELL POLARITY; CELL SIZE; CULTURE TECHNIQUE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; DYSENTERY; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI O157; FLUORESCENCE MICROSCOPY; GENETICS; HUMAN; INTESTINE MUCOSA; METABOLISM; MICROBIOLOGY; NEUTROPHIL; PATHOGENICITY; PHYSIOLOGY; SALMONELLA TYPHIMURIUM; SECRETION; SHIGELLA FLEXNERI; SIGNAL TRANSDUCTION;

ACTINS; CADAVERINE; CARBOXY-LYASES; CELL CULTURE TECHNIQUES; CELL LINE; CELL MOVEMENT; CELL POLARITY; CELL SIZE; DOSE-RESPONSE RELATIONSHIP, DRUG; DYSENTERY; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI O157; HUMANS; INTERLEUKIN-8; INTESTINAL MUCOSA; LYSINE; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PHOSPHOPROTEINS; SALMONELLA TYPHIMURIUM; SHIGELLA FLEXNERI; SIGNAL TRANSDUCTION;

EID: 0033188183     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1462-5822.1999.00014.x     Document Type: Article

References (42)

1. Bardocz, S. (1993) The role of dietary polyamines. Eur J Clin Nutr 47: 683-690.
2. Beatty, W.A., and Sansonetti, P.J. (1997) Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes. Infect Immun 65: 4395-4404.
3. Bennish, M.L. (1991) Potentially lethal complications of Shigellosis. Rev Infect Dis 13 (Suppl. 4): 319-324.
4. Bernardini, M.L., Mounier, J., d'Hauteville, H., Coquis-Rondon, M., and Sansonetti, P.J. (1989) Identification of IcsA a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction of Factin. Proc Natl Acad Sci USA 86: 3867-3871.
5. Chen, L, Hobbie, S., and Galan, J. (1996) Requirement of CDC42 for Salmonella-induced cytoskeletal and nuclear responses. Science 274: 2115-2118.
6. Darveau, R.P., Belton, C.M., and Lamont, R.J. (1998) Local chemokine paralysis, a novel pathogenic mechanism for Porphyromonas gingivalis. Infect Immun 66: 1660-1665.
7. Day, D.W., Mandal, B.K., and Morrson, B.C. (1978) The rectal biopsy appearances in Salmonella colitis. Histopathology 2: 117-131.
8. Eckmann, L, Kagnoff, M., and Fierer, J. (1993) Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect Immun 61: 4569-4574.
9. Elitsur, Y., Moshier, J.A., Murthy, R., Barbish, A., and Luk, G.D. (1992) Polyamine levels, ornithine decarboxylase (ODC) activity, and ODC-mRNA expression in normal and cancerous human colonocytes. Life Sci 50: 1417-1424.
10. Formal, S.B., Dammin, G.J., LaBrec, E.H., and Schneider, H. (1958) Experimental Shigella infections: characteristics of a fatal infection produced in guinea pigs. J Bacteriol 75: 604-610.
11. Goldberg, M.B., and Sansonetti, P.J. (1993) Shigella subversion of the cellular cytoskeleton: a strategy for epithelial colonization. Infect Immun 61: 4941-4946.
12. Gulig, P., and Curtiss, R. III (1987) Plasmid-associated virulence of Salmonella typhimurium. Infect Immun 55: 2891-2901.
13. Hardt, W.-D., Chen, L.-M., Schuebel, K.E., Bustelo, X.R., and Galan, J.E. (1998) S. typhimurium encodes an activator of rho GTPases that induces membrane ruffling and nuclear responses in host cells. Cell 93: 815-826.
14. Henson, P., and Oades, Z.G. (1975) Stimulation of human neutrophils by soluble and insoluble immunoglobulin aggregates. J Clin Invest 56: 1053-1061.
15. Jung, H.C., Eckmann, L., Yang, S.-K., Panja, A., Fierer, J., Morzycka-Wroblewska, E., et al. (1995) A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest 95: 55-65.
16. Kumar, N.B., Nostrant, T.T., and Appelman, H.D. (1982) The histopathologic spectrum of acute self-limited colitis (acute infectious type colitis). Am J Surg Pathol 6: 523-529.
17. McCormack, S.A., Viar, M.J., and Johnson, L.R. (1993) Polyamines are necessary for cell migration by small intestinal crypt cell line. Am J Physiol 264: G367-G374.
18. McCormick, B.A., Colgan, S.P., Archer, C.D., Miller, S.I., and Madara, J.L. (1993) Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils. J Cell Biol 123: 895-907.
19. McCormick, B.A., Hofman, P., Kim, J., Carnes, D., Miller, S., and Madara, J. (1995) Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils. J Cell Biol 131: 1599-1608.
20. McCormick, B.A., Siber, A.M., and Maurelli, AT. (1998a) Requirement of the Shigella flexneri virulence plasmid in the ability to induce trafficking of neutrophils across polarized monolayers of the intestinal epithelium. Infect Immun 66: 4237-4243.
21. McCormick, B.A., Parkos, C.A., Colgan, S.P., Carnes, D.K., and Madara, J.L. (1998b) Apical secretion of a pathogenelicited epithelial chemoattractant (PEEC) activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium. J Immunol 160: 455-466.
22. McGovern, V.J., and Slavutin, L.J. (1979) Pathology of Salmonella colitis. Am J Surg Pathol 3: 483-490.
23. Madara, J.L., and Dharmsathaphorn, K. (1985) Occluding junction structure-function relationships in a cultured monolayer. J Cell Biol 101: 2124-2133.
24. Madara, J.L., Colgan, S.P., Nusrat, C., Delp, C., and Parkos, C.A. (1992) A simple approach to measurement of electrical parameters of cultured epithelial monolayers: use in assessing neutrophil epithelial interactions. J Tissue Culture Methods 14: 209-213.
25. Madianos, P.N., Papapanou, P.N., and Sandros, J. (1997) Porphyromonas gingivalis infection of oral epithelium inhibits neutrophil transepithelial migration. Infect Immun 65: 3983-3990.
26. Makino, S., Sasakawa, C., Kamata, K., Kuata, T., and Yoshihawa, M.A. (1986) A genetic determinant required for continuous reinfection of adjacent cells on the large plasmid of Shigella flexneri-2a. Cell 46: 551-555.
27. Mathan, M.M., and Mathan, V.I. (1986) Ultrastructural pathology of the rectal mucosa in Shigella dysentery. Am J Pathol 123: 25-38.
28. Maurelli, A.T., Blackmon, B., and Curtiss, III, R. (1984) Loss of pigmentation in Shigella flexneri 2a is correlated with loss of virulence and virulence-associated plasmid. Infect Immun 43: 397-401.
29. Maurelli, A.T., Fernandez, R.E., Bloch, C.A., Rode, C.K., and Fasano, A. (1998) 'Black holes' and bacterial pathogenicity: a large genomic deletion that enhances the virulence of Shigella spp. and enteroinvasive Escherichia coli. Proc Natl Acad Sci USA 95: 3943-3948.
30. Meng, S.-Y., and Bennett, G.N. (1992) Nucleotide sequence of the Escherichia coli cad operon: a system for neutralization of low extracellular pH. J Bacteriol 174: 2659-2669.
31. Mounier, J., Vasselon, T., Hellio, R., Lesourd, M., and Sansonetti, P.J. (1992) Shigella flexneri enters human colonic Caco-2 epithelial cells through the basolateral pole. Infect Immun 60: 237-248.
32. Nash, S., Stafford, J., and Madara, J.L. (1987) Effects of polymorphonuclear leukocyte transmigration on barrier function of cultured intestinal epithelial monolayers. J Clin Invest 80: 1104-1113.
33. Park, Y.K., Bearson, B., Bang, I.S., and Foster, J.W. (1996) Internal crisis, lysine decarboxylase and the acid tolerance response of Salmonella typhimurium. Mol Microbiol 20: 605-611.
34. Parkos, C.A., Delp, C., Arnaout, M.A., and Madara, J.L. (1991) Neutrophil migration across a cultured intestinal epithelium: dependence on a CD 11b/CD18-mediated event and enhanced efficiency in the physiologic direction. J Clin Invest 88: 1605-1612.
35. Parkos, C.A., Colgan, S.P., Delp, C., Arnaout, M.A., and Madara, J.L. (1992) Neutrophil migration across a cultured epithelial monolayer elicits a biphasic resistance response representing sequential effects on transcellular and paracellular pathways. J Cell Biol 117: 757-764.
36. Perdomo, J.J., Gounon, P., and Sansonetti, P.J. (1994) Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayers by Shigella flexneri. J Clin Invest 193: 633-643.
37. Rout, W.R., Formal, S.B., Dammin, G.J., and Giannella, R.A. (1974) Pathophysiology of Salmonella diarrhea in the Rhesus monkey: intestinal transport, morphological and bacteriological studies. Gastroenterology 67: 59-70.
38. Samartzidou, H., and Delcour, A.H. (1999) Excretion of endogenous cadaverine leads to a decrease in porin-mediated outer membrane permeability. J Bacteriol 181: 791-798.
39. Sansonetti, P.J., Arondel, J., Huerre, M., Harada, A., and Matsushima, K. (1999) Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis. Infect Immun 67: 1471-1480.
40. Savkovic, S., Koutsouris, A., and Hecht, G. (1997) Activation of NF-kappaB in intestinal epithelial cells by enteropathogenic Escherichia coli. Am J Physiol 273: C1160-C1167.
41. Takeuchi, A. (1967) Electron microscope studies of experimental Salmonella infection. Am J Pathol 50: 109-119.
42. Watarai, M., Kamata, Y., Kozaki, S., and Sasakawa, C. (1997) rho, a small GTP-binding protein, is essential for Shigella invasion of epithelial cells. J Exp Med 185: 281-292.