-
1
-
-
0029670289
-
Protein sorting by transport vesicles
-
Rothman JE, Wieland FT: Protein sorting by transport vesicles. Science 1996, 272:227-234.
-
(1996)
Science
, vol.272
, pp. 227-234
-
-
Rothman, J.E.1
Wieland, F.T.2
-
2
-
-
0029872276
-
Coat proteins and vesicle budding
-
Schekman R, Orci L: Coat proteins and vesicle budding. Science 1996, 271:1526-1533.
-
(1996)
Science
, vol.271
, pp. 1526-1533
-
-
Schekman, R.1
Orci, L.2
-
3
-
-
0032145879
-
Mechanisms of protein sorting and coat assembly: Insights from the clathrin-coated vesicle pathway
-
Le Borgne R, Hoflack B: Mechanisms of protein sorting and coat assembly: Insights from the clathrin-coated vesicle pathway. Curr Opin Cell Biol 1998, 10:499-503.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 499-503
-
-
Le Borgne, R.1
Hoflack, B.2
-
4
-
-
0030814254
-
COPII and secretory cargo capture into transport vesicles
-
Kuehn MJ, Schekman R: COPII and secretory cargo capture into transport vesicles. Curr Opin Cell Biol 1997, 9:477-483.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 477-483
-
-
Kuehn, M.J.1
Schekman, R.2
-
5
-
-
0028233498
-
COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum
-
Barlowe C, Orci L, Yeung T, Hosobuchi M, Hamamoto S, Salama N, Rexach MF, Ravazzola M, Amherdt M, Schekman R: COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 1994, 77:895-908.
-
(1994)
Cell
, vol.77
, pp. 895-908
-
-
Barlowe, C.1
Orci, L.2
Yeung, T.3
Hosobuchi, M.4
Hamamoto, S.5
Salama, N.6
Rexach, M.F.7
Ravazzola, M.8
Amherdt, M.9
Schekman, R.10
-
6
-
-
0027751666
-
Stepwise assembly of functionally active transport vesicles
-
Ostermann J, Orci L, Tani K, Amherdt M, Ravazzola M, Elazar Z, Rothman JE: Stepwise assembly of functionally active transport vesicles. Cell 1993, 75:1015-1025.
-
(1993)
Cell
, vol.75
, pp. 1015-1025
-
-
Ostermann, J.1
Orci, L.2
Tani, K.3
Amherdt, M.4
Ravazzola, M.5
Elazar, Z.6
Rothman, J.E.7
-
7
-
-
0027500969
-
SEC12 encodes a guanine nucleotide exchange factor essential for transport vesicle formation from the ER
-
Barlowe C, Schekman R: SEC12 encodes a guanine nucleotide exchange factor essential for transport vesicle formation from the ER. Nature 1993, 365:347-349.
-
(1993)
Nature
, vol.365
, pp. 347-349
-
-
Barlowe, C.1
Schekman, R.2
-
8
-
-
0029844904
-
A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains
-
Chardin P, Paris S, Antonny B, Robineau S, Beraud Dufour S, Jackson CL, Chabre M: A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains. Nature 1996, 384:481-484.
-
(1996)
Nature
, vol.384
, pp. 481-484
-
-
Chardin, P.1
Paris, S.2
Antonny, B.3
Robineau, S.4
Beraud Dufour, S.5
Jackson, C.L.6
Chabre, M.7
-
9
-
-
0027467275
-
Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins
-
Orci L, Palmer DJ, Ravazzola M, Perrelet A, Amherdt M, Rothman JE: Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins. Nature 1993, 362:648-652.
-
(1993)
Nature
, vol.362
, pp. 648-652
-
-
Orci, L.1
Palmer, D.J.2
Ravazzola, M.3
Perrelet, A.4
Amherdt, M.5
Rothman, J.E.6
-
10
-
-
0030984537
-
Direct and GTP-dependent interaction of ADP ribosylation factor 1 with coatomer subunit beta
-
Zhao L, Helms JB, Bruegger B, Harter C, Martoglio B, Graf R, Brunner J, Wieland FT: Direct and GTP-dependent interaction of ADP ribosylation factor 1 with coatomer subunit beta. Proc Natl Acad Sci USA 1997, 94:4418-4423.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4418-4423
-
-
Zhao, L.1
Helms, J.B.2
Bruegger, B.3
Harter, C.4
Martoglio, B.5
Graf, R.6
Brunner, J.7
Wieland, F.T.8
-
11
-
-
0033553388
-
GTP-dependent binding of ADP-ribosylation factor to coatomer in close proximity to the binding site for dilysine retrieval motifs and p23
-
Zhao L, Helms JB, Brunner J, Wieland FT: GTP-dependent binding of ADP-ribosylation factor to coatomer in close proximity to the binding site for dilysine retrieval motifs and p23. J Biol Chem 1999, 274:14198-14203.
-
(1999)
J Biol Chem
, vol.274
, pp. 14198-14203
-
-
Zhao, L.1
Helms, J.B.2
Brunner, J.3
Wieland, F.T.4
-
12
-
-
0027467609
-
Requirement for a GTPase-activating protein in vesicle budding from the endoplasmic reticulum
-
Yoshihisa T, Barlowe C, Schekman R: Requirement for a GTPase-activating protein in vesicle budding from the endoplasmic reticulum. Science 1993, 259:1466-1468.
-
(1993)
Science
, vol.259
, pp. 1466-1468
-
-
Yoshihisa, T.1
Barlowe, C.2
Schekman, R.3
-
13
-
-
0029416828
-
The ARF1 GTPase activating protein: Zinc finger motif and Golgi complex localization
-
Cukierman E, Huber I, Rotman M, Cassel D: The ARF1 GTPase activating protein: Zinc finger motif and Golgi complex localization. Science 1995, 270:1999-2002.
-
(1995)
Science
, vol.270
, pp. 1999-2002
-
-
Cukierman, E.1
Huber, I.2
Rotman, M.3
Cassel, D.4
-
14
-
-
0033582917
-
Structural and functional analysis of the ARF1 ARFGAP complex reveals a role for coatomer in GTP hydrolysis
-
Goldberg J: Structural and functional analysis of the ARF1 ARFGAP complex reveals a role for coatomer in GTP hydrolysis. Cell 1999, 96:893-902. Based on the crystal structure of ARF1-ARFGAP it is suggested that ARFGAP can stimulate GTP hydrolysis while ARF1 maintains an interaction with coatomer. Data from biochemical experiments are presented showing that coatomer directly participates in the GTPase reaction, accelerating the rate of GTP hydrolysis in an ARF-GTP dependent manner. It is discussed how coatomer binding to ARF1-GTP might stimulate its GTPase activity.
-
(1999)
Cell
, vol.96
, pp. 893-902
-
-
Goldberg, J.1
-
15
-
-
0028181745
-
Coatomer interaction with di-lysine endoplasmic reticulum retention motifs
-
Cosson P, Letourneur F: Coatomer interaction with di-lysine endoplasmic reticulum retention motifs. Science 1994, 263:1629-1631.
-
(1994)
Science
, vol.263
, pp. 1629-1631
-
-
Cosson, P.1
Letourneur, F.2
-
16
-
-
0029874257
-
Nonclathrin coat protein gamma, a subunit of coatomer, binds to the cytoplasmic dilysine motif of membrane proteins of the early secretory pathway
-
Harter C, Pavel J, Coccia F, Draken E, Wegehingel S, Tschochner H, Wieland F: Nonclathrin coat protein gamma, a subunit of coatomer, binds to the cytoplasmic dilysine motif of membrane proteins of the early secretory pathway. Proc Natl Acad Sci USA 1996,93:1902-1906.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1902-1906
-
-
Harter, C.1
Pavel, J.2
Coccia, F.3
Draken, E.4
Wegehingel, S.5
Tschochner, H.6
Wieland, F.7
-
17
-
-
0031964997
-
Getting through the Golgi complex
-
Pelham HRB: Getting through the Golgi complex. Trends Cell Biol 1998, 8:45-49.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 45-49
-
-
Pelham, H.R.B.1
-
18
-
-
0032146589
-
The organisation of the Golgi apparatus
-
Warren G, Malhotra V: The organisation of the Golgi apparatus. Curr Opin Cell Biol 1998, 10:493-498.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 493-498
-
-
Warren, G.1
Malhotra, V.2
-
19
-
-
0032495477
-
COPII-cargo interactions direct protein sorting into ER-derived transport vesicles
-
Kuehn MJ, Herrmann JM, Schekman R: COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. Nature 1998, 391:187-190. This paper provides data showing that membrane and soluble cargo proteins of COPII vesicles are present in prebudding complexes with the COPII components Sar1p and Sec23p-Sec24p. Furthermore, members of the v-SNARE and p24 families are also found in COPII complexes. These data indicate that COPII recruitment complexes recognize packaging signals in cargo proteins and putative cargo receptors.
-
(1998)
Nature
, vol.391
, pp. 187-190
-
-
Kuehn, M.J.1
Herrmann, J.M.2
Schekman, R.3
-
20
-
-
0029836930
-
COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI
-
Rowe T, Aridor M, McCaffery JM, Plutner H, Nuoffer C, Balch WE: COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI. J Cell Biol 1996, 135:895-911.
-
(1996)
J Cell Biol
, vol.135
, pp. 895-911
-
-
Rowe, T.1
Aridor, M.2
McCaffery, J.M.3
Plutner, H.4
Nuoffer, C.5
Balch, W.E.6
-
21
-
-
0032489878
-
Cargo selection by the COPII budding machinery during export from the ER
-
Aridor M, Weissman J, Bannykh S, Nuoffer C, Balch WE: Cargo selection by the COPII budding machinery during export from the ER. J Cell Biol 1998, 141:61-70. Mammalian Sec23p-24p complex is shown to be able to form a prebudding complex at the ER membrane with the type I membrane cargo protein VSV-G in a Sar1p dependent manner. Subsequent addition of mammalian Sec13p-Sec31p complex results in packaging of the cargo into COPII vesicles. Thus, roles for Sec23p complex in cargo sorting, and for Sec13p in COPII budding are discussed.
-
(1998)
J Cell Biol
, vol.141
, pp. 61-70
-
-
Aridor, M.1
Weissman, J.2
Bannykh, S.3
Nuoffer, C.4
Balch, W.E.5
-
22
-
-
0026604647
-
Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum
-
Lewis MJ, Pelham HR: Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum. Cell 1992, 68:353-364.
-
(1992)
Cell
, vol.68
, pp. 353-364
-
-
Lewis, M.J.1
Pelham, H.R.2
-
23
-
-
0030755580
-
Bidirectional transport by distinct populations of COPI-coated vesicles
-
Orci L, Stamnes M, Ravazzola M, Amherdt M, Perrelet A, Söllner TH, Rothman JE: Bidirectional transport by distinct populations of COPI-coated vesicles. Cell 1997, 90:335-349.
-
(1997)
Cell
, vol.90
, pp. 335-349
-
-
Orci, L.1
Stamnes, M.2
Ravazzola, M.3
Amherdt, M.4
Perrelet, A.5
Söllner, T.H.6
Rothman, J.E.7
-
24
-
-
0028964475
-
The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi
-
Schimmoeller F, Singer-Krueger B, Schroeder S, Krueger U, Barlowe C, Riezman H: The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi. EMBO J 1995, 14:1329-1339.
-
(1995)
EMBO J
, vol.14
, pp. 1329-1339
-
-
Schimmoeller, F.1
Singer-Krueger, B.2
Schroeder, S.3
Krueger, U.4
Barlowe, C.5
Riezman, H.6
-
25
-
-
0029147574
-
An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding
-
Stamnes MA, Craighead MW, Hoe MH, Lampen N, Geromanos S, Tempst P, Rothman JE: An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding. Proc Natl Acad Sci USA 1995, 92:8011-8015.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8011-8015
-
-
Stamnes, M.A.1
Craighead, M.W.2
Hoe, M.H.3
Lampen, N.4
Geromanos, S.5
Tempst, P.6
Rothman, J.E.7
-
26
-
-
0030443308
-
A major membrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding
-
Sohn K, Orci L, Ravazzola M, Amherdt M, Bremser M, Lottspeich F, Fiedler K, Helms JB, Wieland FT: A major membrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding. J Cell Biol 1996, 135:1239-1248.
-
(1996)
J Cell Biol
, vol.135
, pp. 1239-1248
-
-
Sohn, K.1
Orci, L.2
Ravazzola, M.3
Amherdt, M.4
Bremser, M.5
Lottspeich, F.6
Fiedler, K.7
Helms, J.B.8
Wieland, F.T.9
-
27
-
-
0029910214
-
Erv25p, a component of COPII-coated vesicles, forms a complex with Emp24p that is required for efficient endoplasmic reticulum to Golgi transport
-
Belden WJ, Barlowe C: Erv25p, a component of COPII-coated vesicles, forms a complex with Emp24p that is required for efficient endoplasmic reticulum to Golgi transport. J Biol Chem 1996, 271:26939-26946.
-
(1996)
J Biol Chem
, vol.271
, pp. 26939-26946
-
-
Belden, W.J.1
Barlowe, C.2
-
28
-
-
0030055357
-
Tmp21 and p24a, two type 1 proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking
-
Blum R, Feick P, Puype M, Vandekerckhove J, Klengel R, Nastainczyk W, Schulz I: Tmp21 and p24a, two type 1 proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking. J Biol Chem 1996, 271:17183-17189.
-
(1996)
J Biol Chem
, vol.271
, pp. 17183-17189
-
-
Blum, R.1
Feick, P.2
Puype, M.3
Vandekerckhove, J.4
Klengel, R.5
Nastainczyk, W.6
Schulz, I.7
-
29
-
-
0030782187
-
Involvement of the transmembrane protein p23 in biosynthetic protein transport
-
Rojo M, Pepperkok R, Emery G, Kellner R, Stang E, Parton RG, Gruenberg J: Involvement of the transmembrane protein p23 in biosynthetic protein transport. J Cell Biol 1997, 139:1119-1135.
-
(1997)
J Cell Biol
, vol.139
, pp. 1119-1135
-
-
Rojo, M.1
Pepperkok, R.2
Emery, G.3
Kellner, R.4
Stang, E.5
Parton, R.G.6
Gruenberg, J.7
-
30
-
-
0029796074
-
Bimodal interaction of coatomer with the p24 family of putative cargo receptors
-
Fiedler K, Veit M, Stamnes MA, Rothman JE: Bimodal interaction of coatomer with the p24 family of putative cargo receptors. Science 1996, 273:1396-1399.
-
(1996)
Science
, vol.273
, pp. 1396-1399
-
-
Fiedler, K.1
Veit, M.2
Stamnes, M.A.3
Rothman, J.E.4
-
31
-
-
0030868332
-
p23, a major COPI vesicle membrane protein, constitutively cycles through the early secretory pathway
-
Nickel W, Sohn K, Bunning C, Wieland FT: p23, a major COPI vesicle membrane protein, constitutively cycles through the early secretory pathway. Proc Natl Acad Sci USA 1997, 94:11393-11398.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11393-11398
-
-
Nickel, W.1
Sohn, K.2
Bunning, C.3
Wieland, F.T.4
-
32
-
-
0032559651
-
gp25l/emp24/p24 protein family members of the cis-Golgi network bind both COPI and II coatomer
-
Dominguez M, Dejgaard K, Füllekrug J, Dahan S, Fazel A, Paccaud J-P, Thomas DY, Bergeron JJM, Nilsson T: gp25l/emp24/p24 protein family members of the cis-Golgi network bind both COPI and II coatomer. J Cell Biol 1998, 140:751-765.
-
(1998)
J Cell Biol
, vol.140
, pp. 751-765
-
-
Dominguez, M.1
Dejgaard, K.2
Füllekrug, J.3
Dahan, S.4
Fazel, A.5
Paccaud, J.-P.6
Thomas, D.Y.7
Bergeron, J.J.M.8
Nilsson, T.9
-
33
-
-
0032971476
-
p24 and p23, the major transmembrane proteins of COPI-coated transport vesicles, form hetero-oligomeric complexes and cycle between the organelles of the early secretory pathway
-
Gommel D, Orci L, Emig EM, Hannah MJ, Ravazzola M, Nickel W, Helms JB, Wieland FT, Sohn K: p24 and p23, the major transmembrane proteins of COPI-coated transport vesicles, form hetero-oligomeric complexes and cycle between the organelles of the early secretory pathway. FEBS Lett 1999, 447:179-185.
-
(1999)
FEBS Lett
, vol.447
, pp. 179-185
-
-
Gommel, D.1
Orci, L.2
Emig, E.M.3
Hannah, M.J.4
Ravazzola, M.5
Nickel, W.6
Helms, J.B.7
Wieland, F.T.8
Sohn, K.9
-
34
-
-
0027965738
-
Characteristics of endoplasmic reticulum-derived transport vesicles
-
Rexach MF, Latterich M, Schekman RW: Characteristics of endoplasmic reticulum-derived transport vesicles. J Cell Biol 1994, 126:1133-1148.
-
(1994)
J Cell Biol
, vol.126
, pp. 1133-1148
-
-
Rexach, M.F.1
Latterich, M.2
Schekman, R.W.3
-
35
-
-
0030014854
-
A v-SNARE implicated in intra Golgi transport
-
Nagahama M, Orci L, Ravazzola M, Amherdt M, Lacomis L, Tempst P, Rothman JE, Soellner TH: A v-SNARE implicated in intra Golgi transport J Cell Biol 1996, 133:507-516.
-
(1996)
J Cell Biol
, vol.133
, pp. 507-516
-
-
Nagahama, M.1
Orci, L.2
Ravazzola, M.3
Amherdt, M.4
Lacomis, L.5
Tempst, P.6
Rothman, J.E.7
Soellner, T.H.8
-
36
-
-
0027413655
-
SNAP receptors implicated in vesicle targeting and fusion
-
Soellner T, Whiteheart SW, Brunner M, Erdjument BH, Geromanos S, Tempst P, Rothman JE: SNAP receptors implicated in vesicle targeting and fusion. Nature 1993, 362:318-324.
-
(1993)
Nature
, vol.362
, pp. 318-324
-
-
Soellner, T.1
Whiteheart, S.W.2
Brunner, M.3
Erdjument, B.H.4
Geromanos, S.5
Tempst, P.6
Rothman, J.E.7
-
37
-
-
0028385277
-
Implications of the SNARE hypothesis for intracellular membrane topology and dynamics
-
Rothman JE, Warren G: Implications of the SNARE hypothesis for intracellular membrane topology and dynamics. Curr Biol 1994, 4:220-233.
-
(1994)
Curr Biol
, vol.4
, pp. 220-233
-
-
Rothman, J.E.1
Warren, G.2
-
38
-
-
0032516856
-
SNAREs and membrane fusion in the Golgi apparatus
-
Nichols BJ, Pelham HR: SNAREs and membrane fusion in the Golgi apparatus. Biochim Biophys Acta 1998, 1404:9-31.
-
(1998)
Biochim Biophys Acta
, vol.1404
, pp. 9-31
-
-
Nichols, B.J.1
Pelham, H.R.2
-
39
-
-
0032584717
-
Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs
-
Springer S, Schekman R: Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs. Science 1998, 281:698-700. This authors of this paper show that fusion proteins containing the cytoplasmic domains of the v-SNAREs Bet1p and Bos1p can interact with Sec23p in a Sar1p and GTP dependent manner. This suggests that v-SNAREs can be taken up into COPII vesicles by a direct interaction with coat components.
-
(1998)
Science
, vol.281
, pp. 698-700
-
-
Springer, S.1
Schekman, R.2
-
40
-
-
0032215324
-
Coat assembly directs v-SNARE concentration into synthetic COPII vesicles
-
Matsuoka K, Morimitsu Y, Uchida K, Schekman R: Coat assembly directs v-SNARE concentration into synthetic COPII vesicles. Mol Cell 1998, 2:703-708. Using a liposome budding experiment, the v-SNARE Sec22p is shown to be selectively enriched in COPII-coated vesicles. These data suggest a role of COPII components in concentration of transmembrane cargo, such as v-SNAREs.
-
(1998)
Mol Cell
, vol.2
, pp. 703-708
-
-
Matsuoka, K.1
Morimitsu, Y.2
Uchida, K.3
Schekman, R.4
-
41
-
-
0033582648
-
Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors
-
Bremser M, Nickel W, Schweikert M, Ravazzola M, Amherdt M, Hughes CA, Sollner TH, Rothman JE, Wieland FT: Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors. Cell 1999, 96:495-506. In vitro reconstitution of COPI vesicles from chemically defined liposomes shows that all that is needed to bud a COPI-coated vesicle are the cytosolic proteins ARF1 and coatomer and the cytoplasmic domains of putative coat/cargo receptors (p24 proteins) in the presence of GTP and an elevated temperature. It is suggested that a bivalent interaction of coatomer with ARF1-GTP and with p24 proteins provides the molecular basis for coat assembly and cargo selection.
-
(1999)
Cell
, vol.96
, pp. 495-506
-
-
Bremser, M.1
Nickel, W.2
Schweikert, M.3
Ravazzola, M.4
Amherdt, M.5
Hughes, C.A.6
Sollner, T.H.7
Rothman, J.E.8
Wieland, F.T.9
-
42
-
-
0023052287
-
A new type of coated vesicular carrier that appears not to contain clathrin: Its possible role in protein transport within the Golgi stack
-
Orci L, Glick BS, Rothman JE: A new type of coated vesicular carrier that appears not to contain clathrin: Its possible role in protein transport within the Golgi stack. Cell 1986, 46:171-184.
-
(1986)
Cell
, vol.46
, pp. 171-184
-
-
Orci, L.1
Glick, B.S.2
Rothman, J.E.3
-
43
-
-
0032530193
-
Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes
-
Spang A, Matsuoka K, Hamamoto S, Schekman R, Orci L: Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes. Proc Natl Acad Sci USA 1998, 95:11199-11204.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11199-11204
-
-
Spang, A.1
Matsuoka, K.2
Hamamoto, S.3
Schekman, R.4
Orci, L.5
-
44
-
-
18344405156
-
COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes
-
Matsuoka K, Orci L, Amherdt M, Bednarek SY, Hamamoto S, Schekman R, Yeung T: COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes. Cell 1998, 93:263-275. In vitro reconstitution with chemically defined liposomes shows that the soluble proteins Sar1p, Sec13p-Sec31p and Sec23p-Sec24p are sufficient for COPII vesicle formation provided that certain phospholipids are present in the lipid bilayer. This finding is important as it points to the assembly of COPII coat proteins as the driving force for the formation of a bud.
-
(1998)
Cell
, vol.93
, pp. 263-275
-
-
Matsuoka, K.1
Orci, L.2
Amherdt, M.3
Bednarek, S.Y.4
Hamamoto, S.5
Schekman, R.6
Yeung, T.7
-
45
-
-
0033574003
-
Receptor-induced polymerization of coatomer
-
Reinhard C, Harter C, Bremser M, Brugger B, Sohn K, Helms JB, Wieland F: Receptor-induced polymerization of coatomer. Proc Natl Acad Sci USA 1999, 96:1224-1228. This study shows that interaction of soluble coatomer with a peptide corresponding to the cytoplasmic domain of p23 induces a conformational change of the complex leading to its polymerization. Coat polymerization induced by specific coat receptors might represent a general principle to shape a membrane into a bud.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1224-1228
-
-
Reinhard, C.1
Harter, C.2
Bremser, M.3
Brugger, B.4
Sohn, K.5
Helms, J.B.6
Wieland, F.7
-
46
-
-
0032578522
-
A single binding site for dilysine retrieval motifs and p23 within the gamma subunit of coatomer
-
Harter C, Wieland FT: A single binding site for dilysine retrieval motifs and p23 within the gamma subunit of coatomer. Proc Natl Acad Sci USA 1998, 95:11649-11654. This paper provides data showing that under native conditions the cytoplasmic domain of p23 interacts with coatomer exclusively via its γ-subunit and shares its binding site with a KKXX ER-retrieval motif. Importantly, upon dissociation of coatomer, interactions of the p23 peptide with various COPs, including an α-, β′-, ε-COP subcomplex, are observed. This finding has clarified controversy about the direct binding partner of p24 family members to coatomer.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11649-11654
-
-
Harter, C.1
Wieland, F.T.2
-
47
-
-
0031738937
-
Uptake by COPI-coated vesicles of both anterograde and retrograde cargo is inhibited by GTP γS in vitro
-
Nickel W, Malsam J, Gorgas K, Ravazzola M, Jenne N, Helms JB, Wieland FT: Uptake by COPI-coated vesicles of both anterograde and retrograde cargo is inhibited by GTP γS in vitro. J Cell Sci 1998, 111:3081-3090. COPI-coated vesicles generated in vitro from isolated Golgi membranes in the presence of the poorly hydrolyzable GTP analogue, GTPγS, are found to contain low amounts of anterograde and retrograde cargo. In contrast, both types of cargo are included in COPI vesicles generated in the presence of GTP. This observation suggests that hydrolysis of GTP is needed for the uptake of cargo into a COPI vesicle.
-
(1998)
J Cell Sci
, vol.111
, pp. 3081-3090
-
-
Nickel, W.1
Malsam, J.2
Gorgas, K.3
Ravazzola, M.4
Jenne, N.5
Helms, J.B.6
Wieland, F.T.7
-
48
-
-
0027263507
-
Binding of coatomer to Golgi membranes requires ADP-ribosylation factor
-
Palmer DJ, Helms JB, Beckers CJ, Orci L, Rothman JE: Binding of coatomer to Golgi membranes requires ADP-ribosylation factor. J Biol Chem 1993, 268:12083-12089.
-
(1993)
J Biol Chem
, vol.268
, pp. 12083-12089
-
-
Palmer, D.J.1
Helms, J.B.2
Beckers, C.J.3
Orci, L.4
Rothman, J.E.5
-
49
-
-
0030772378
-
The Ras-RasGAP complex: Structural basis for GTPase activation and its loss in oncogenic Ras mutants
-
Scheffzek K, Ahmadian MR, Kabsch W, Wiesmuller L, Lautwein A, Schmitz F, Wittinghofer A: The Ras-RasGap complex: Structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science 1997, 277:333-338.
-
(1997)
Science
, vol.277
, pp. 333-338
-
-
Scheffzek, K.1
Ahmadian, M.R.2
Kabsch, W.3
Wiesmuller, L.4
Lautwein, A.5
Schmitz, F.6
Wittinghofer, A.7
-
50
-
-
0031784899
-
ASAP1, a phospholipid-dependent ARF GTPase-activating protein that associates with and is phosphorylated by Src
-
Brown MT, Andrade J, Radhakrishna H, Donaldson JG, Cooper JA, Randazzo PA: ASAP1, a phospholipid-dependent ARF GTPase-activating protein that associates with and is phosphorylated by Src. Mol Cell Biol 1998, 18:7038-7051.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 7038-7051
-
-
Brown, M.T.1
Andrade, J.2
Radhakrishna, H.3
Donaldson, J.G.4
Cooper, J.A.5
Randazzo, P.A.6
-
51
-
-
0032564277
-
β2-adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
-
Premont RT, Claing A, Vitale N, Freeman JL, Pitcher JA, Patton WA, Moss J, Vaughan M, Lefkowitz RJ: β2-adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein. Proc Natl Acad Sci USA 1998, 95:14082-14087.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14082-14087
-
-
Premont, R.T.1
Claing, A.2
Vitale, N.3
Freeman, J.L.4
Pitcher, J.A.5
Patton, W.A.6
Moss, J.7
Vaughan, M.8
Lefkowitz, R.J.9
-
52
-
-
0033019056
-
Identification of a new Pyk2 target protein with ARF-GAP activity
-
Andreev J, Simon J-P, Sabatini DD, Kam J, Plowman G, Randazzo PA, Schlessinger J: Identification of a new Pyk2 target protein with ARF-GAP activity. Mol Cell Biol 1999, 19:2338-2350.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2338-2350
-
-
Andreev, J.1
Simon, J.-P.2
Sabatini, D.D.3
Kam, J.4
Plowman, G.5
Randazzo, P.A.6
Schlessinger, J.7
-
53
-
-
0033081078
-
Retrograde transport from the yeast Golgi is mediated by two ARF GAP proteins with overlapping function
-
Poon PP, Cassel D, Spang A, Rotman M, Pick E, Singer RA, Johnston GC: Retrograde transport from the yeast Golgi is mediated by two ARF GAP proteins with overlapping function. EMBO J 1999, 18:555-564.
-
(1999)
EMBO J
, vol.18
, pp. 555-564
-
-
Poon, P.P.1
Cassel, D.2
Spang, A.3
Rotman, M.4
Pick, E.5
Singer, R.A.6
Johnston, G.C.7
-
54
-
-
0032174618
-
Protein and lipid sorting between the endoplasmic reticulum and the Golgi complex
-
Nickel W, Brügger B, Wieland F: Protein and lipid sorting between the endoplasmic reticulum and the Golgi complex. Sem Cell Dev Biol 1998, 9:493-501.
-
(1998)
Sem Cell Dev Biol
, vol.9
, pp. 493-501
-
-
Nickel, W.1
Brügger, B.2
Wieland, F.3
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