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Enhanced phosphorylation of p53 by ATM in response to DNA damage
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Usui T, Ohta T, Oshiumi H, Tomizawa J, Ogawa H, Ogawa T: Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell 1998, 95:705-716. This paper describes the functional characterization of the yeast Mre11 protein using a combination of biochemical and genetic assays. In addition to agreeing with results in [38••,39••], this paper shows that there is an additional DNA-binding domain in the middle of the Mre11 protein and that meiosis specific proteins interact with the carboxyl terminus of the protein.
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Haber JE: The many interfaces of Mre11. Cell 1998, 95:583-586. This review provides a clear and concise description of the function of the Mre11-Rad50 complex in several different DNA metabolic pathways.
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