De novo expression of lipocortin-1 in reactive microglia and astrocytes in kainic acid lesioned rat cerebellum

GLIA

Volumn 26, Issue 4, 1999, Pages 333-343

  Young, Karen A ^a   Hirst, Warren D ^a   Solito, Egle ^b   Wilkin, Graham P ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b INSTITUT COCHIN   (France)

Author keywords

Inflammation; Injury; Kainic acid lesion; Neuroprotection; Reactive gliosis

Indexed keywords

ASTROCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOCALIZATION; KAINIC ACID; LIPOCORTIN 1; MICROGLIA; NERVE CELL;

ANIMALS; ANNEXIN A1; ASTROCYTES; CEREBELLUM; HUMANS; KAINIC ACID; MALE; MICROGLIA; RATS;

EID: 0033152762     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(199906)26:4<333::AID-GLIA7>3.0.CO;2-S     Document Type: Article

References (59)

1. Andersson P, Perry VH, Gordon S. 1991. The kinetics and morphological characteristics of the macrophage-microglial response to kainic-acid induced neuronal degeneration. Neuroscience 42:201-214.
2. Bazan NG, Allan G. 1996. Platelet-activating factor is both a modulator of synaptic function and a mediator of cerebral injury and inflammation. Adv Neurol 71:475-482.
3. Becherucci C, Perretti M, Solito E, Galeotti CL, Parente L. 1993. Conceivable difference in the anti-inflammatory mechanisms of lipocortins 1 and 5. Mediators Inflam 2:109-113.
4. Benzi G, Moretti A. 1995. Are reactive oxygen species involved in Alzheimer's disease? Neurobiol Aging 16:661-674.
5. Black MD, Carey F, Crossman AR, Relton JK, Rothwell NJ. 1992. Lipocortin-1 inhibits NMDA receptor-mediated neuronal damage in the striatum of the rat. Brain Res 585:135-140.
6. Blackwell GJ, Carnuccio R, Di-Rosa M, Flower RJ, Parente L, Persico P. 1980. Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids. Nature 287:147-149.
7. 2. Nature 390:622-625.
8. Buckingham JC. 1996. Stress and the neuroendocrine-immune axis: the pivotal role of glucocorticoids and lipocortin 1. Br J Pharmacol 118:1-19.
9. Chao CC, Hu S, Peterson PK. 1996. Glia: the not so innocent bystanders. J Neurovirol 2:234-239.
10. Christmas P, Callaway J, Fallon J, Jones J, Haigler HT. 1991. Selective secretion of annexin 1, a protein without a signal sequence, by the human prostate gland. J Biol Chem 266:2499-2507.
11. Cirino G, Peers SH, Wallace JL, Flower RJ. 1989. A study of phospholipase A2-induced oedema in rat paw. Eur J Pharmacol 166:505-510.
12. Colton C, Wilt S, Gilbert D, Chernyshev O, Snell J, Dubois-Dalcq M. 1996. Species differences in the generation of reactive oxygen species by microglia. Mol Chem Neuropathol 28:15-20.
13. Croxtall JD, Flower RJ. 1992. Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line. Proc Natl Acad Sci USA 89:3571-3575.
14. De Caterina R, Sicari R, Giannessi D, Paggiaro PL, Paoletti P, Lazzerini G, Bernini W, Solito E, Parente L. 1993. Macrophage-specific eicosanoid synthesis inhibition and lipocortin-1 induction by glucocorticoids. J Appl Physiol 75:2368-2375.
15. Decker T, Lohmann-Matthes ML. 1988. A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity. J Immunol Methods 115:61-69.
16. Eddlestone M, Mucke L. 1993. Molecular profile of reactive astrocytes-Implications for their role in neurologic disease. Neuroscience 54:15-36.
17. Elderfleld AJ, Bolton C, Flower RJ. 1993. Lipocortin l (annexin 1) immunoreactivity in the cervical spinal cord of Lewis rats with acute experimental allergic encephalomyelitis. J Neurol Sci 119:146-153.
18. Flower RJ. 1988. Lipocortin and the mechanism of action of the glucocorticoids. Br J Pharmacol 94:987-1015.
19. Flower RJ, Rothwell NJ. 1994. Lipocortin-1: cellular mechanisms and clinical relevance. Trends Pharmacol Sci 15:71-76.
20. Gebicke-Haerter PJ, Schobert A, Dieter P, Honegger P, Hertting G. 1991. Regulation and glucocorticoid-independent induction of lipocortin I in cultured astrocytes. J Neurochem 57:175-183.
21. Getting SJ, Flower RJ, Perretti M. 1997. Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. Br J Pharmacol 120:1075-1082.
22. Goulding NJ, Guyre PM. 1992. Regulation of inflammation by lipocortin 1. Immunol Today 13:295-297.
23. Goulding NJ, Pan L, Wardwell K, Guyre VC, Guyre PM. 1996. Evidence for specific annexin I-binding proteins on human monocytes. Biochem J 316:593-597.
24. Huitinga I, Bauer J, Strijbos PJLM, Rothwell NJ, Dijkstra CD. 1998. Effect of annexin-1 on experimental autoimmune encephabmyelitis (EAE) in the rat. Clin Exp Immunol 111:198-204.
25. Jenner P, Olanow CW. 1996. Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 47 161-170.
26. Johnson MD, Kamso-Pratt JM, Whetsell WO, Pepinsky RB. 1989. Lipocortin-1 immunoreactivity in the normal human central nervous system and lesions with astrocytosis. Am J Clin Pathol 92:424-429.
27. Kettenman H, Ransom BR, editors. 1995. Neuroglia. Oxford: Oxford University Press.
28. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
29. Ling EA, Kaur LC, Yick TY, Wong WC. 1990. Immunocytochemical localization of CR3 complement receptors with OX-42 in amoeboid microglia in postnatal rats. Anat Embryol 182:481-486.
30. Loddick SA, Wong ML, Bongiorno PB, Gold PW, Licinio J, Rothwell NJ. 1997. Endogenous interleukin-1 receptor antagonist is neuroprotective. Biochem Biophys Res Commun 234:211-215.
31. Ma AS, Ozers LJ. 1996. Annexins I and II show differences in subcellular localization and differentiation-related changes in human epidermal keratinocytes. Arch Dermatol Res 288:596-603.
32. Marriott DR, Hirst WD, Ljungberg MC. 1995. Astrocytes. In: Cohen J, Wilkin GP, editors. Neural cell culture: a practical approach. Oxford: Oxford University Press, p 85-96.
33. McKanna JA. 1993. Lipocortin 1 immunoreactivity identifies microglia in adult rat brain. J Neurosci Res 36:491-500.
34. McKanna JA, Zhang M. 1997. Immunohistochemical localization of lipocortin 1 in rat brain is sensitive to pH, freezing and dehydration. J Histochem Cytochem 45:527-538.
35. McLeod JD, Bolton C. 1995. Dexamethasone induces an increase in intracellular and membrane-associated lipocortin-1 (annexin-1) in rat astrocyte primary cultures. Cell Mol Neurobiol 15:193-205.
36. Moreno JJ. 1996. Antiflammin-2, a nonapeptide of lipocortin-1, inhibits leukocyte chemotaxis but not arachidonic acid mobilization Eur J Pharmacol 314:129-135
37. Mullens L, Marriott DR, Young KA, Tannahill L, Lightman SL, Wilkin GP. 1994. Up-regulation of lipocortin-1 and its mRNA in reactive astrocytes in kainate-lesioned rat cerebellum. J Neuroimmunol 50:25-33.
38. Pepinsky RB, Sinclair LK, Browning JL, Mattaliano RJ, Smart JE, Chow EP, Falbel T, Ribolini A, Garwin JL, Wallner BP. 1986. Purification and partial sequence analysis of a 37-kDa protein that inhibits phospholipase A2 activity from rat peritoneal exudates. J Biol Chem 261:4239-4246.
39. Pepinsky RB, Sinclair LK, Dougas I, Liang CM, Lawton P, Browning JL. 1990. Monoclonal antibodies to lipocortin-1 as probes for biological function. FEBS Lett 261:247-252.
40. Perretti M, Flower RJ. 1993. Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1. J Immunol 150:992-999
41. Perretti M, Croxtall JD, Wheller SK, Goulding NJ, Hannon R, Flower RJ. 1996. Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration. Nature Med 2:1259-1262.
42. Philip JG, Flower RJ, Buckingham JC. 1997. Glucocorticoids modulate the cellular disposition of lipocortin 1 in the rat brain in vivo and in vitro. Neuroreport 8:1871-1876.
43. Piani D, Constam DB, Frei K, Fontana A. 1994. Macrophages in the brain: Friends or Enemies? NIPS 9:80-84.
44. Raynal P, Pollard HB. 1994. Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium-and phospholipid-binding proteins. Biochim Biophys Acta 1197:63-93.
45. Relton JK, Strijbos PJ, O'Shaughnessy CT, Carey F, Forder RA, Tilders FJ, Rothwell NJ. 1991. Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain. J Exp Med 174:305-310.
46. Ridet JL, Malhotra SK, Privat A, Gage FH. 1997. Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 20:570-577.
47. Robinson AP, White TM, Mason DW. 1986. Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. Immunology 57:239-247.
48. Smith SF, Goulding NJ, Godolphin JL, Tetley TD, Roberts CM, Guz A, Flower RJ. 1990. An assay for the assessment of lipocortin 1 levels in human lung lavage fluid. J Immunol Methods 131:119-125.
49. Smith T, Flower RJ, Buckingham JC. 1993. Lipocortins 1, 2 and 5 in the central nervous system and pituitary gland of the rat: selective induction by dexamaethasone of lipocortin 1 in the anterior pituitary gland. Mol Neuropharmacol 3:45-55.
50. Solito E, De Caterina R, Giannessi D, Paggiaro PL, Sicari R, Parente L. 1993. Studies on the induction of lipocortin-1 by glucocorticoids. Ann 1st Super Sanita 29:391-394.
51. Staub F, Winkler A, Peters J, Kempski O, Kachel V, Baethmann A. 1994. Swelling, acidosis, and irreversible damage of glial cells from exposure to arachidonic acid in vitro. J Cereb Blood Flow Metab 14:1030-1039.
52. Streit WJ. 1996. The role of microglia in brain injury. Neurotoxicology 17:671-678.
53. Strijbos PJ, Tilders FJ, Carey F, Forder R, Rothwell NJ. 1991. Localization of immunoreactive lipocortin-1 in the brain and pituitary gland of the rat: effects of adrenalectomy, dexamethasone and colchicine treatment. Brain Res 553:249-260.
54. Violette SM, King I, Browning JL, Pepinsky RB, Wallner BP, Sartorelli AC. 1990. Role of lipocortin I in the glucocorticoid induction of the terminal differentiation of a human squamous carcinoma. J Cell Physiol 142:70-77.
55. Voermans PH, Go KG, Ter Host GJ, Ruiters MHJ, Solito E, Parente L. 1996. Induction of annexin-1 at transcriptional and post-transcriptional level in rat brain by methylprednisolone and the 21-aminosteroid U74389F. Mediators Inflam 5:370-378.
56. Williams AE, van Dam AM, Man-A-Hing WK, Berkenbosch F, Eikelenboom P, Fraser H. 1994. Cytokines, prostaglandins and lipocortin-1 are present in the brains of scrapie-infected mice. Brain Res 654:200-206.
57. 2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations. Brain Res 754:171-180.
58. Wood PL. 1995. Microglia as a unique cellular target in the treatment of stroke: potential neurotoxic mediators produced by activated microglia. Neurol Res 17:242-248.
59. Yang GY, Zhao YJ, Davidson BL, Betz AL. 1997. Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury. Brain Res 751:181-188.