Carbon catabolite repression in bacteria

Current Opinion in Microbiology

Volumn 2, Issue 2, 1999, Pages 195-201

  Stülke, Jörg ^a   Hillen, Wolfgang ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL GROWTH; CARBON DIOXIDE FIXATION; ESCHERICHIA COLI; GENE EXPRESSION; GROWTH RATE; NONHUMAN; PROTEIN PHOSPHORYLATION; REVIEW;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0033118267     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(99)80034-4     Document Type: Article

References (58)

1. Postma PW, Lengeler JW, Jacobson GR: Phosphoenolpyruvate: Carbohydrate phosphotransferase systems of bacteria. Microbiol Rev 1993, 57:543-594.
2. Deutscher J, Fischer C, Charrier V, Galinier A, Lindner C, Darbon E, Dossonet V: Regulation of carbon metabolism in Gram-positive bacteria by protein phosphorylation. Folia Microbiol 1997, 42:171-178. A discussion of the implication of PTS-dependent protein phosphorylation in bacterial carbon catabolism.
3. Stülke J, Arnaud M, Rapoport G, Martin-Verstraete I: PRD - A protein domain involved in PTS-dependent induction and carbon catabolite repression of catabolic operons in bacteria. Mol Microbiol 1998, 28:865-874. Definition of the PTS regulation domain and review on its role in the regulation of catabolic operons.
4. Stülke J, Hillen W: Coupling physiology and gene regulation in bacteria: The phosphotransferase sugar uptake system delivers the signals. Naturwissenschaften 1998, 85:583-592.
5. ts mutant. J Biol Chem 1995, 270:4822-4839.
6. Fraser CM, Morris SJ, Weinstock GM, White O, Button GG, Dodson R, Gwinn M, Mickey EK, Clayton R, Ketchum KA et al.: Complete genome sequence of Treponema pallidum, the syphilis spirochete. Science 1998, 281:375-388.
7. Inada T, Kimata K, Aiba H: Mechanism responsible for glucose-lactose diauxie in Escherichia coli: Challenge to the cAMP model. Genes to Cells 1996, 1:293-301.
8. Hogema BM, Arents JC, Inada T, Aiba H, van Dam K, Postma PW: Catabolite repression by glucose-6-phosphate, gluconate and lactose in Escherichia coli. Mol Microbiol 1997, 24:857-867. The first molecular study on CCR of the E. coli lac operon by non-PTS carbon sources.
9. Kimata K, Takahashi H, Inada T, Postma P, Aiba H: CAMP receptor protein - CAMP plays a crucial role in glucose-lactose diauxie by activating the major glucose transporter gene in Escherichia coli. Proc Natl Acad Sci USA 1997, 94:12914-12919. A detailed analysis of the contribution of cAMP to glucose/lactose diauxie.
10. Hogema BM, Arents JC, Bader R, Eijkemans K, Inada T, Aiba H, Postma PW: Inducer exclusion by glucose-6-phosphate in Escherichia coli. Mol Microbiol 1998, 28:755-765.
11. Glc and thus the activity of adenylate cyclase.
12. Glc of the phosphoenolpyruvate:Sugar phosphotransferase system. J Bacteriol 1998, 180:732-736.
13. Glc, the glucose-specific phosphotransferase protein, in Escherichia coli. Mol Gen Genet 1998, 259:317-326.
14. Notley-McRobb L, Death A, Ferenci T: The relationship between external glucose concentration and cAMP levels inside Escherichia coli: Implications for models of phosphotransferase-mediated regulation of adenylate cyclase. Microbiology 1997, 143:1909-1918.
15. Galinier A, Kravanja M, Engelmann R, Hengstenberg W, Kilhoffer MC, Deutscher J, Haiech J: New protein kinase and protein phosphatase families mediate signal transduction in bacterial catabolite repression. Proc Natl Acad Sci USA 1998, 95:1823-1828. Identification and characterization of the gene encoding HPr kinase, the major component in CCR of B. subtilis.
16. Reizer J, Hoischen C, Titgemeyer F, Rivolta C, Rabus R, Stülke J, Karamata D, Saier MH, Hillen W: A novel bacterial protein kinase that controls carbon catabolite repression. Mol Microbiol 1998, 27:1157-1170. Characterization of B. subtilis HPr kinase and its implication in CCR.
17. Vadeboncoeur C, Pelletier M: The phosphoenolpyruvate:Sugar phosphotransferase system of oral streptococci and its role in the control of sugar metabolism. FEMS Microbiol Rev 1997, 19:187-207.
18. Mitchell WJ: Physiology of carbohydrate to solvent conversion by clostridia. Adv Microb Physiol 1998, 39:31-130.
19. Hueck CJ, Hillen W: Catabolite repression in Bacillus subtilis: A global regulatory mechanism for the Gram-positive bacteria? Mol Microbiol 1995, 15:395-401.
20. Charrier V, Buckley E, Parsonage D, Galinier A, Darbon E, Jaquinod M, Forest E, Deutscher J, Claiborne A: Cloning and sequencing of two enterococcal glpK genes and regulation of the encoded glycerol kinases by phosphoenolpyruvate-dependent, phosphotransferase system-catalyzed phosphorylation of a single histidyl residue. J Biol Chem 1997, 272:14166-14174. Phosphorylation of a catabolic enzyme by HPr is demonstrated.
21. Henkin TM: The role of the CcpA transcriptional regulator in carbon metabolism in Bacillus subtilis. FEMS Microbiol Lett 1996, 135:9-15.
22. Küster E, Luesink EJ, de Vos WM, Hillen W: Immunological crossreactivity to the catabolite control protein CcpA from Bacillus megaterium is found in many Gram-positive bacteria. FEMS Microbiol Lett 1996, 139:109-115.
23. Egeter O, Brückner R: Catabolite repression mediated by the catabolite control protein CcpA in Staphylococcus xylosus. Mol Microbiol 1996, 21:739-749.
24. Monedero V, Gosalbes MJ, Perez-Martinez G: Catabolite repression in Lactobacillus casei ATCC 393 is mediated by CcpA. J Bacteriol 1997, 179:6657-6664.
25. Lokman BC, Heerikhuisen M, Leer RJ, van den Broek A, Borsboom Y, Chaillou S, Postma PW, Pouwels PH: Regulation of expression of the Lactobacillus pentosus xylAb operon. J Bacteriol 1997, 179:5391-5397.
26. Simpson CL, Russell RRB: Identification of a homolog of CcpA catabolite represser protein in Streptococcus mutans. Infect Immun 1998, 66:2085-2092.
27. Fujita Y, Miwa Y, Galinier A, Deutscher J: Specific recognition of the Bacillus subtilis gnt cis-acting catabolite-responsive element by a protein complex formed between CcpA and seryl-phosphorylated HPr. Mol Microbiol 1995, 17:953-960.
28. Martin-Verstraete I, Stülke J, Klier A, Rapoport G: Two different mechanisms mediate catabolite repression of the Bacillus subtilis levanase operon. J Bacteriol 1995, 177:6919-6927.
29. Krüger S, Hecker M: Regulation of the putative bgIPH operon for aryl-β-glucoside utilization in Bacillus subtilis. J Bacteriol 1995, 177:5590-5597.
30. Shaw GC, Kao HS, Chiou CY: Cloning, expression, and catabolite repression of a gene encoding β-galactosidase of Bacillus megaterium ATCC14581. J Bacteriol 1998, 180:4734-4738.
31. Marasco R, Muscariello L, Varcamonti M, de Felice M, Sacco M: Expression of the bgIH gene of Lactobacillus plantarum is controlled by carbon catabolite repression. J Bacteriol 1998, 180:3400-3404.
32. Zalieckas JM, Wray LV, Ferson AE, Fisher SH: Transcription-repair coupling factor is involved in carbon catabolite repression of the Bacillus subtilis hut and gnt operons. Mol Microbiol 1998, 27:1031-1038. This paper demonstrates the transcription machinery is differentially implicated in CCR of several catabolic operons.
33. Gösseringer R, Küster E, Galinier A, Deutscher J, Hillen W: Cooperative and non-cooperative DNA binding modes of catabolite control protein CcpA from Bacillus megaterium result from sensing two different signals. J Mol Biol 1997, 266:665-676. Glucose-6-phosphate is demonstrated to be an alternative corepressor for CcpA.
34. Galinier A, Haiech J, Kilhoffer MC, Jaquinod M, Stülke J, Deutscher J, Martin-Verstraete I: The Bacillus subtilis crh gene encodes a HPr-like protein involved in carbon catabolite repression. Proc Natl Acad Sci USA 1997, 94:8439-8444. A HPr-like protein uniquely involved in regulation is identified and characterized.
35. Miwa Y, Nagura K, Eguchi S, Fukuda H, Deutscher J, Fujita Y: Catabolite repression of the Bacillus subtilis gnt operon exerted by two catabolite-responsive elements. Mol Microbiol 1997, 23:1203-1213. Modulation of DNA-binding of CcpA by glucose-6-phosphate is shown.
36. Kim JH, Voskuil MI, Chambliss GH: NADP, corepressor for the Bacillus subtilis catabolite control protein CcpA. Proc Natl Acad Sci USA 1998, 95:9590-9595. NADP is identified as a corepressor of CcpA especially important for inhibition of transcription.
37. Jones BE, Dossonnet V, Küster E, Hillen W, Deutscher J, Klevit RE: Binding of the catabolite repressor protein CcpA to its DNA target is regulated by phosphorylation of its corepressor HPr. J Biol Chem 1997, 272:26530-26535. Structural analysis of the ternary complex that results in CCR in B. subtilis. The location of the binding site for CcpA on HPr-S46-P was identified.
38. Kraus A, Küster E, Wagner A, Hoffmann K, Hillen W: Identification of a corepressor binding site in catabolite control protein CcpA. Mol Microbiol 1998, 30:955-963.
39. Stülke J, Martin-Verstraete I, Charrier V, Klier A, Deutscher J, Rapoport G: The HPr protein of the phosphotransferase system links induction and catabolite repression of the Bacillus subtilis levanase operon. J Bacteriol 1995,177:6928-6936.
40. Krüger S, Gertz S, Hecker M: Transcriptional analysis of bgIPH expression in Bacillus subtilis: Evidence for two distinct pathways mediating carbon catabolite repression. J Bacteriol 1996, 178:2637-2644.
41. Reizer J, Saier MH Jr: Modular multidomain phosphoryl transfer proteins of bacteria. Curr Opin Struct Biol 1997, 7:407-415.
42. Martin-Verstraete I, Charrier V, Stülke J, Galinier A, Erni B, Rapoport G, Deutscher J: Antagonistic effects of dual PTS catalyzed phosphorylation on the Bacillus subtilis transcriptional activator LevR. Mol Microbiol 1998, 28:293-303. The phosphorylation sites and the sources of phosphorylation are for the first time elucidated for a PRD-containing transcriptional regulator.
43. Wehtje C, Beijer L, Nilsson RP, Rutberg B: Mutations in the glycerol kinase gene restore the ability of a ptsGHI mutant of Bacillus subtilis to grow on glycerol. Microbiology 1995, 141:1193-1198.
44. Saier MH Jr, Chauvaux S, Cook GM, Deutscher J, Paulsen IT, Reizer J, Ye JJ: Catabolite repression and inducer control in Gram-positive bacteria. Microbiology 1996, 142:217-230.
45. Wagner E, Marcandier S, Egeter O, Deutscher J, Götz F, Brückner R: Glucose kinase-dependent catabolite repression in Staphylococcus xylosus. J Bacteriol 1995, 177:6144-6152.
46. Titgemeyer F, Walkenhorst J, Reizer J, Stuiver MH, Cui X, Saier MH Jr: Identification and characterization of phosphoenolpyruvate:Fructose phosphotransferase systems in three Streptomyces species. Microbiology 1995, 141:51-58.
47. Hodgson DA: Glucose repression of carbon source uptake in Streptomyces coelicolor A3(2) and its perturbation in mutants resistant to 2-deoxyglucose. J Gen Microbiol 1982, 128:2417-2430.
48. Kwakman JHJM, Postma PW: Glucose kinase has a regulatory role in carbon catabolite repression in Streptomyces coelicolor. J Bacteriol 1994, 176:2694-2698.
49. Seno ET, Chater KF: Glycerol catabolic enzymes and their regulation in wild-type and mutant strains of Streptomyces coelicolor A3(2). J Gen Microbiol 1983, 129:1403-1413.
50. Saito A, Fujii T, Yoneyama T, Miyashita K: GlkA is involved in glucose repression of chitinase production in Streptomyces lividans. J Bacteriol 1998, 180:2911-2914.
51. Angell S, Lewis CG, Buttner MJ, Bibb MJ: Glucose repression in Streptomyces coelicolor A3(2): A likely regulatory role for glucose kinase. Mol Gen Genet 1994, 244:135-143.
52. van Wezel GP, White J, Young P, Postma PW, Bibb MJ: Substrate induction and glucose repression of maltose utilization by Streptomyces coelicolor A3(2) is controlled by malR, a member of the lacl-galR family of regulatory genes. Mol Microbiol 1997, 23:537-549. The operon-specific negative regulator MalR is shown to be invlolved in CCR of the mal operon in S. coelicolor.
53. Nguyen J, Francou F, Virolle MJ, Guérineau M: Amylase and chitinase genes in Streptomyces lividans are regulated by reg1, a pleiotropic regulatory gene. J Bacteriol 1997, 179:6383-6390.
54. Hindle Z, Smith CP: Substrate induction and catabolite repression of the Streptomyces coelicolor glycerol operon are mediated through the GyIR protein. Mol Microbiol 1994, 12:737-745.
55. Ni X, Westpheling J: Direct repeat sequences in the Streptomyces chitinase-63 promoter direct both glucose repression and chitin induction. Proc Natl Acad Sci USA 1997, 94:13116-13121. Identification of a cis-active target of both CCR and induction in Streptomyces.
56. Collier DN, Hager PW, Phibbs PV Jr: Catabolite repression control in the Pseudomonads. Res Microbiol 1996, 147:551-561.
57. Müller C, Petruschka L, Cuypers H, Burchhardt G, Herrmann H: Carbon catabolite repression of phenol degradation in Pseudomonas putida is mediated by the inhibition of the activator protein PhlR. J Bacteriol 1996, 178:2030-2036.
58. Pries A, Priefert H, Krüger N, Steinbüchel A: Identification and characterization of two Alcaligenes eutrophus gene loci relevant to the poly(β-hydroxybutyric acid)-leaky phenotype which exhibit homology to ptsH and ptsl of Escherichia coli. J Bacteriol 1991, 173:5843-5853.