Substrate induction and glucose repression of maltose utilization by Streptomyces coelicolor A3(2) is controlled by malR, a member of the lacI-galR family of regulatory genes

Molecular Microbiology

Volumn 23, Issue 3, 1997, Pages 537-549

  Van Wezel, Gilles P ^a   White, Janet ^a   Young, Peter ^b   Postma, Pieter W ^c   Bibb, Mervyn J ^a  

^a JOHN INNES CENTRE   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; MALTOSE;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE REPRESSION; GLUCOSE UTILIZATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; STREPTOMYCES COELICOLOR; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 0031018158     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1997.d01-1878.x     Document Type: Article

References (70)

1. Angell, S., Lewis, C.G., Buttner, M.J., and Bibb, M.J. (1994) Glucose repression in Streptomyces coelicolor A3(2): a likely regulatory role for glucose kinase. Mol Gen Genet 244: 135-143.
2. Aubert, M., Weber, E., Schneider, D., Simonet, J.M., and Decaris, B. (1993) Primary structure analysis of a duplicated region in the amplifiable AUD6 locus of Streptomyces ambofaciens DSM40697. FEMS Microbiol Lett 113:49-56.
3. Bahri, S.M., and Ward, J.M. (1990) Regulation of a thermostable α-amylase of Streptomyces thermoviolaceus CUB74 - maltotriose is the smallest inducer. Biochimie 72: 893-895.
4. Bibb, M.J., Jones, G.H., Joseph, R., Buttner, M.J., and Ward, J.M. (1987) The agarase gene (dagA) of Streptomyces coelicolor A3(2): affinity purification and characterisation of the cloned gene product. J Gen Microbiol 133: 2089-2096.
5. Bierman, M., Logan, R., O'Brien, K., Seno, E.T., Rao, R.N., and Schoner, B.E. (1992) Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. Gene 116: 43-49.
6. Buttner, M.J., and Brown, N.L. (1985) RNA polymerase-DNA interactions in Streptomyces. In vitro studies of a S. lividans plasmid promoter with S. coelicolor RNA polymerase. J Mol Biol 185: 177-188.
7. Buttner, M.J., Fearnley, I.M., and Bibb, M.J. (1987) The agarase gene (dagA) of Streptomyces coelicolor A3(2): nucleotide sequence and transcriptional analysis. Mol Gen Genet 209: 101-109.
8. Chater, K.P., and Losick, R. (1996) The mycelial life-style of Streptomyces coelicolor A3(2) and its relatives. In Bacteria as Multicellular Organisms. Shapiro, J.H., and Dworkin, M. (eds). New York: Oxford University Press, in press.
9. Chater, K.F., Bruton, C.J., King, A.A., and Suarez, J.E. (1982) The expression of Streptomyces and Escherichia coli drug resistance determinants cloned into the Streptomyces phage øC31. Gene 19: 21-32.
10. Chatterjee, S., and Vining, L.C. (1982) Catabolite repression in Streptomyces venezuelae - induction of β-galactosidase, chloramphenicol production, and intracellular cyclic adenosine-3′,5′-monophosphate concentrations. Can J Microbiol 28: 311-317.
11. Covarrubias, L., and Bolivar, F. (1982) Construction and characterisation of new cloning vehicles, VI. Plasmid pBR329, a new derivative of pBR328 lacking the 482 base pair inverted duplication. Gene 17: 79-89.
12. Dahl, M.K., Schmiedel, D., and Hillen, W. (1995) Glucose and glucose-6-phosphate interaction with Xyl repressor proteins from Bacillus spp. may contribute to regulation of xylose utilization. J Bacteriol 177: 5467-5472.
13. Delić, I., Robbins, P., and Westpheling, J. (1992) Direct repeat sequences are implicated in the regulation of two Streptomyces chitinase promoters that are subject to carbon catabolite control Proc Natl Acad Sci USA 89: 1885-1889.
14. Duplay, P., Bedouelle, H., Fowler, A., Zabin, I., Saurin, W., and Hofnung, M. (1984) Sequences of the malE gene and of its product, the maltose-binding protein of Escherichia coli K-12. J Biol Chem 259: 10606-10613.
15. Egeter, O., and Brückner, R. (1995) Characterization of a genetic locus essential for maltose-maltotriose utilization in Staphylococcus xylosus. J Bacteriol 171: 2408-2415.
16. Egeter, O., and Brückner, R. (1996) Catabolite repression mediated by the catabolite control protein CcpA in Staphylococcus xylosus. Mol Microbiol 21: 739-749.
17. Flores, M.E., Ponce, E., Rubio, M., and Huitron, C. (1993) Glucose and glycerol repression of α-amylase in Streptomyces kanamyceticus and isolation of deregulated mutants. Biotechnol Lett 15: 595-600.
18. Graefe, U., Bormann, E.J., Roth, M., and Neigenfind, M. (1986) Mutants of Streptomyces hygroscopicus deregulated in amylase and α-glucosidase formation. Biotechnol Lett 8: 615-620.
19. Henkin, T.M. (1996) The role of the CcpA transcriptional regulator in carbon metabolism in Bacillus subtilis. FEMS Microbiol Lett 135: 9-15.
20. Henkin, T.M., Grundy, F.J., Nicholson, W.L., and Chambliss, G.M. (1991) Catabolite repression of α-amylase gene expression in Bacillus subtilis involves a frans-acting gene product homologous to the Escherichia coli lacl and galR repressors. Mol Microbiol 5: 575-584.
21. Hindle, Z., and Smith, C.P. (1994) Substrate induction and catabolite repression of the Streptomyces coelicolor glycerol operon are mediated through the GyIR protein. Mol Microbiol 12: 737-745.
22. Hobbs, G., Frazer, C.M., Gardner, D.C.J., Flett, F., and Oliver, S.G. (1989) Dispersed growth of Streptomyces in liquid culture. Appl Microbiol Biotechnol 31: 272-277.
23. Hodgson, D.A. (1980) Carbohydrate utilisation in Streptomyces coelicolor A3(2). PhD thesis. University of East Anglia, Norwich, UK.
24. Hodgson, D.A. (1982) Glucose repression of carbon source uptake and metabolism in Streptomyces coelicolor A3(2) and its perturbation in mutants resistant to 2-deoxyglucose. J Gen Microbiol 128: 2417-2430.
25. Hopwood, D.A., Bibb, M.J., Chater, K.F., Kieser, T., Bruton, C.J., Kieser, H.M., Lydiate, D.J., Smith, C., Ward, J.M., and Schrempf, H. (1985) Genetic Manipulation of Streptomyces: A Laboratory Manual. Norwich, UK: John Innes Foundation.
26. Hueck, C., and Hillen, W.D.R. (1995) Catabolite repression in Bacillus subtilis: a global regulatory mechanism for the Gram-positive bacteria? Mol Microbiol 15: 395-401.
27. Hueck, C., Kraus, A., and Hillen, W.D.R. (1994) Sequences of ccpA and two downstream Bacillus megaterium genes with homology to the motAB operon from Bacillus subtilis. Gene 143: 147-148.
28. Inada, T., Kimata, K., and Aiba, H. (1996) Mechanism responsible for glucose-lactose diauxie in Escherichia coli: challenge to the cAMP model. Genes Cells 1: 293-301.
29. Janssen, G.R. (1993) Eubacterial, archaebacterial, and eukaryotic genes that encode leaderless mRNA. In Industrial Microorganisms: Basic And Applied Molecular Genetics. Baltz, R.H., Hegeman, G.D., and Skatrud, P.L. (eds). Washington DC: American Society for Microbiology, pp. 59-67.
30. Kelemen, G.H., Plaskitt, K.A., Lewis, C.G., Findlay, K.C., and Buttner, M.J. (1995) Deletion of DNA lying close to the glkA locus induces ectopic sporulation in Streptomces coelicolor A3(2). Mol Microbioi 17: 221-230.
31. Küster, E., Luesink, E.J., de Vos, W.M., and Hillen, W. (1996) Immunological crossreactivity to the catabolite control protein CcpA from Bacillus megaterium is found in many Gram-positive bacteria. FEMS Microbiol Lett 139: 109-115.
32. Kwakman, J.H.J.M., and Postma, P.W. (1994) Glucose kinase has a regulatory role in carbon catabolite repression in Streptomyces coelicolor. J Bacteriol 176: 2694-2698.
33. Long, C.M., Virolle, M.J., Chang, S.Y., Chang, S., and Bibb, M.J. (1987) α-amylase gene of Streptomyces limosus - nucleotide sequence, expression motifs, and amino acid sequence homology to mammalian and invertebrate α-amylases. J Bacteriol 169: 5745-5754.
34. McCarthy, A.J., and Williams, S.T. (1992) Actinomycetes as agents of biodegradation in the environment - a review. Gene 115: 189-192.
35. MacNeil, D.J., Gewain, K.M., Ruby, C.L., Dezeny, G., Gibbons, P.H., and MacNeil, T. (1992) Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilising a novel integration vector. Gene 111: 1-68.
36. Messing, J., Crea, R., and Seeburg, P.M. (1981) A system for shotgun DNA sequencing. Nucleic Acids Res 9: 309-321.
37. Miyadoh, S. (1993) Research on antibiotic screening in Japan over the last decade: a producing-microorganisms approach. Actinomycetol 7: 100-106.
38. Murray, M.G. (1986) Use of sodium trichloroacetate and mung bean nuclease to increase sensitivity and precision during transcript mapping. Anal Biochem 158: 165-170.
39. Novotná, J., and Hostálek, Z. (1985) Phosphorylation of hexoses in Streptomyces aureofaciens: evidence that the phosphoenolpyruvate: sugar phosphotransferase system is not operative. FEMS Microbiol Lett 28: 347-350.
40. Piendl, W., Eichenseer, C., Viel, P., Altenbuchner, J., and Cullum, J. (1994) Analysis of putative DNA amplification genes in the element AUDI of Streptomyces lividans 66. Mol Gen Genet 244: 439-443.
41. Postma, P.W., Lengeler, J.W., and Jacobson, G.R. (1993) Phosphoenolpyruvate: carbohydrate phosphotransferase systems of bacteria. Microbiol Rev 57: 543-594.
42. Postma, P.W., Lengeler, J.W., and Jacobson, G.R. (1996) Phosphoenolpyruvate: carbohydrate phosphotransferase systems. In Escherichia coli and Salmonella typhimurium. Cellular and Molecular Biology. Neidhardt, F.C. (ed.). Washington, DC: American Society for Microbiology, pp. 1149-1174.
43. Puyet, A., and Espinosa, M. (1993) Structure of the maltodextrin-uptake locus of Streptococcus pneumoniae. J Mol Biol 230: 800-811.
44. Puyet, A., Ibanez, A.M., and Espinoza, M. (1993) Characterization of the Streptococcus pneumoniae maltosaccharide regulator MalR, a member of the Lacl-GalR family of repressors displaying distinctive general features. J Biol Chem 268: 25402-25408.
45. Redenbach, M., Kieser, H.M., Denapaite, D., Eichner, A., Cullum, J., Kinashi, H., and Hopwood, D.A. (1996) A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome. Mol Microbiol 21: 77-96.
46. Reidl, J., Roemisch, K., Ehrmann, M., and Boos, W. (1989) Mall, a novel protein involved in regulation of the maltose system of Escherichia coli, is highly homologous to the represser proteins GaIR, CytR, and Lacl. J Bacteriol 171: 4888-4899.
47. Sabater, B., Sebastian, J., and Asensio, C. (1972) Identification and properties of an inducible and highly specific fructokinase from Streptomyces violaceoruber. Biochim Biophys Acta 284: 414-420.
48. Saitou, N., and Nei, M. (1987) The neighbor joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4: 406-425.
49. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
50. Sanger, F., Nicklen, S., and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463-5467.
51. Scheler, A., and Hillen, W. (1993) Glucose is an anti-inducer for the Bacillus licheniformis encoded Xyl repressor. FEMS Microbiol Lett 107: 299-302.
52. Schmiedel, D., and Hillen, W. (1996) Contributions of XylR, CcpA and cre to diauxic growth of Bacillus megaterium and to xylose isomerase expression in the presence of glucose and xylose. Mol Gen Genet 250: 259-266.
53. Seno, E.T., and Chater, K.F. (1983) Glycerol catabolic enzymes and their regulation in wild-type and mutant strains of Streptomyces coelicolor A3(2). J Gen Microbiol 129: 1403-1413.
54. Servín-González, L., Roland Jensen, M., White, J., and Bibb, M.J. (1994) Transcriptional regulation of four promoters of the agarase gene (dagA) of Streptomyces coelicolorA3(2). Microbiol 140: 2555-2565.
55. Strauch, E., Takano, E., Baylis, H.A., and Bibb, M.J. (1991) The stringent response in Streptomyces coelicolor A3(2). Mol Microbiol 5: 289-298.
56. Strohl, W.R. (1992) Compilation and analysis of DNA sequences associated with apparent streptomycete promoters. Nucleic Acids Res 20: 961-974.
57. Thompson, J.D., Higgins, D.G., and Gibson, T.J. (1994) CLUSTAL w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680.
58. Titgemeyer, F., Walkenhorst, J., Reizer, J., Stuiver, M.H., Cui, X., and Saier, M.H. (1995) Identification and characterization of phosphoenolpyruvate: fructose phosphotransferase systems in three Streptomyces species. Microbiol 141: 51-58.
59. Valentin-Hansen, P., Larsen, J.E.L., Hojrup, P., Short, S.A., and Barbier, C.S. (1986) Nucleotide sequence of the cytR regulatory gene of E. coli K-12. Nucleic Acids Res 14: 2215-2228.
60. Vijgenboom, E., Woudt, L.P., Heinstra, P.W.H., Rietveld, K., van Haarlem, J., van Wezel, G.P., Shochat, S., and Bosch, L. (1994) Three tuf-like genes in the kirromycin producer Streptomyces ramocissimus. Microbiol 140: 983-998.
61. Virolle, M.-J., and Bibb, M.J. (1988) Cloning, characterization and regulation of an α-amylase gene from Streptomyces limosus. Mol Microbiol 2: 197-208.
62. Virolle, M.-J., and Gagnat, J. (1994) Sequences involved in growth-phase-dependent expression and glucose repression of a Streptomyces α-amylase gene. Microbiol 140: 1059-1067.
63. Virolle, M.-J., Long, C.M., Chang, S., and Bibb, M.J. (1988) Cloning, characterization and regulation of an α-amylase gene from Streptomyces venezuelae. Gene 74: 321-334.
64. Volff, J.-N., Eichenseer, C., Vieil, P., Piendl, W., and Altenbuchner, J. (1996) Nucleotide sequence and role in DNA amplification of the direct repeats composing the amplifiable element AUDI of Streptomyces lividans 66. Mol Microbiol 21: 1037-1047.
65. Wagner, E., Marcandier, S., Egeter, O., Deutscher, J., Götz, F., and Brückner, R. (1995) Glucose kinase-dependent catabolite repression in Staphylococcus xylosus. J Bacteriol 177: 6144-6152.
66. Ward, J.M., Janssen, G.R., Kieser, T., Bibb, M.J., Buttner, M.J., and Bibb, M.J. (1986) Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator. Mol Gen Genet 203: 468-475.
67. Weickert, M.J., and Adhya, S. (1992) A family of bacterial regulators homologous to Gal and Lac repressors. J Biol Chem 267: 15869-15874.
68. van Wezel, G.P., Vijgenboom, E., and Bosch, L. (1991) A comparative study of the ribosomal RNA operons of Streptomyces coelicolor A3(2) and sequence analysis of rrnA. Nucleic Acids Res 19: 4399-4403.
69. Wu, P.C., Srinivasan, K.V., and Kendrick, K.E. (1995) Regulated expression of the histidase structural gene in Streptomyces griseus. J Bacteriol 177: 854-857.
70. Yanisch-Perron, C., Vieira, J., and Messing, J. (1985) Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13 mp18 and pUC19 vectors. Gene 33: 103-119.