CRP down-regulates adenylate cyclase activity by reducing the level of phosphorylated IIA(Glc), the glucose-specific phosphotransferase protein, in Escherichia coli

Molecular and General Genetics

Volumn 259, Issue 3, 1998, Pages 317-326

  Takahashi, H ^a   Inada, T ^a   Postma, P ^b   Aiba, H ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Adenylate cyclase; cAMP level; CRP; IIA(Glc); Phosphorylation state

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; GLUCOSE TRANSPORTER; HISTIDINE; PHOSPHOTRANSFERASE; RECEPTOR PROTEIN;

ARTICLE; DOWN REGULATION; ENZYME PHOSPHORYLATION; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

ADENYLATE CYCLASE; CARRIER PROTEINS; CYCLIC AMP; CYCLIC AMP RECEPTOR PROTEIN; DOWN-REGULATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENES, BACTERIAL; GLUCOSE; HISTIDINE; MODELS, BIOLOGICAL; MUTATION; PHOSPHOENOLPYRUVATE SUGAR PHOSPHOTRANSFERASE SYSTEM; PHOSPHORYLATION; SEQUENCE DELETION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0031686015     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050818     Document Type: Article

References (45)

1. Aiba H (1985) Transcription of the Escherichia coli adenylate cyclase gene is negatively regulated by cAMP-cAMP receptor protein. J Biol Chem 260:3063-3070
2. Aiba H, Adhya S, de Crombrugghe B (1981) Evidence for two functional gal promoters in intact Escherichia coli cells. J Biol Chem 256:1905-11910
3. Aiba H, Fujimoto S, Ozaki N (1982) Molecular cloning and nucleotide sequencing of the gene for E. coli cAMP receptor protein. Nucleic Acids Res 10:1345-1361
4. Biek DP, Cohen SN (1986) Identification and characterization of recD, a gene affecting plasmid maintenance and recombination in Escherichia coli. J Bacteriol 167:594-603
5. Botsford JL, Harman JG (1992) Cyclic AMP in prokaryotes. Microbiol Rev 56:100-122
6. Buettner MJ, Spitz E, Rickenberg HV (1973) Cyclic adenosine 3′:5′-monophosphate in Escherichia coli. J Bacteriol 14:1068-1073
7. Crasnier M, Danchin A (1990) Characterization of Escherichia coli adenylate cyclase mutants with modified regulation. J Gen Microbiol 136:1825-1831
8. Crasnier M, Danchin A (1994) The catalytic domain of Escherichia coli adenylate cyclase as revealed by deletion analysis of the cya gene. Mol Gen Genet 243:409-416
9. De Reuse H, Danchin A (1988) The ptsH, ptsI, and crr genes of the Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system: a complex operon with several modes of transcription. J Bacteriol 170:3827-3837
10. Glc of the phosphoenolpyruvate: sugar phosphotransferase system in crp strains of Salmonella typhimurium. J Bacteriol 164:477-478
11. Glc of the Escherichia coli phosphotransferase system. Eur J Biochem 144:113-119
12. Eilen E, Pampeno C, Krakow JS (1978) Production and properties of the a core derived from the cyclic adenosine monophosphate receptor protein of Escherichia coli. Biochemistry 17: 2469-2473
13. Epstein W, Rothman-Denes LB, Hesse J (1975) Adenosine 3′:5′-cyclic monophosphate as mediator of catabolite repression in Escherichia coli. Proc Natl Acad Sci USA 72:2300-2304
14. Fandl JP, Thorner LK, Artz SW (1990) Mutations that affect transcription and cyclic AMP-CRP regulation of the adenylate cyclase gene (cya) of Salmonella typhimurium. Genetics 125:719-727
15. Feldheim DA, Chin AM, Nierva CT, Feucht BU, Cao YW, Xu YF, Sutrina SL, Saier MH Jr (1990) Physiological consequences of the complete loss of phosphoryl-transfer proteins HPr and FPr of the phosphoenolpyruvate: sugar phosphotransferase system and analysis of fructose (fru) operon expression in Salmonella typhimurium. J Bacteriol 172:5459-5469
16. Feucht BU, Saier MH Jr (1980) Fine control of adenylate cyclase by the phosphoenolpyruvate: sugar phosphotransferase system in Escherichia coli and Salmonella typhimurium. J Bacteriol 141:603-610
17. Inada T, Kimata K, Aiba H (1996a) Mechanism responsible for glucose-lactose diauxie in Escherichia coli: challenge to cAMP model. Genes Cells 1:293-301
18. Inada T, Takahashi H, Mizuno T, Aiba H (1996b) Down-regulation of cAMP production by cAMP receptor protein in Escherichia coli: an assessment of contributions of transcriptional and control of adenylate cyclase. Mol Gen Genet 253:198-204
19. Ishizuka H, Hanamura A, Kunimura T, Aiba H (1993) A lowered concentration of cAMP receptor protein caused by glucose is an important determinant for catabolite repression in Escherichia coli. Mol Microbiol 10:341-350
20. Jovanovitch, SB (1985) Regulation of a cya-lac fusion by cyclic AMP in Salmonella typhimurium. J Bacteriol 161:641-649
21. Kawamukai M, Kishimoto J, Utsumi R, Himeno M, Komano T, Aiba H (1985) Negative regulation of adenylate cyclase gene (cya) expression by cAMP-CRP in Escherichia coli: studies with cya-lac protein and operon fusion plasmids. J Bacteriol 164:872-877
22. Kimata K, Takahashi H, Inada T, Postma P, Aiba H (1997) CRP-cAMP plays a crucial role in glucose-lactose diauxie by activating the major glucose transporter gene in Escherichia coli. Proc Natl Acad Sci USA 94:12914-12919
23. Kohara Y, Akiyama K, Isono K (1987) The physical map of the whole E coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50:495-508
24. Kolb A, Busby S, Buc H, Garges S, Adhya S (1993) Transcriptional regulation by cAMP and its receptor protein. Annu Rev Biochem 62:749-95
25. Levy S, Zeng G-Q, Danchin A (1990) Cyclic AMP synthesis in Escherichia coli strains bearing known deletions in the pts phosphotransferase operon. Gene 86:27-33
26. Makman RS, Sutherland EW (1965) Adenosine 3′,5′-phosphate in Escherichia coli. J Biol Chem 240:1309-1314
27. Glc) from Salmonella typhimurium. J Biol Chem 257:14526-14537
28. Meadow ND, Fox DK, Roseman S (1990) The bacterial phosphoenolpyruvate:glycose phosphotransferase system. Annu Rev Biochem 59:497-542
29. Miller JH (1972) Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
30. Mori K, Aiba H (1985) Evidence for negative control of cya transcription by cAMP and cAMP receptor protein in intact Escherichia coli cells. J Biol Chem 260:14838-14843
31. Nelson SO, Scholte BJ, Postma PW (1982) Phosphoenolpyruvate: glucose phosphotransferase system-mediated regulation of carbohydrate metabolism in Salmonella typhimurium. J Bacteriol 150:604-615
32. Glc. Eur J Biochem 154:337-341
33. Ninfa AJ, Ninfa EG, Lupas AN, Stock A, Magasanik B, Stock J (1988) Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism. Proc Natl Acad Sci USA 85:5492-5496
34. Plumbridge J (1998) Control of the expression of the manXYZ operon in Escherichia coli: M1c is a negative regulator of the mannose PTS. Mol Microbiol 27:369-380
35. Postma PW, Lengeler JW, Jacobson GR (1993) Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria. Microbiol Rev 57:543-594
36. Glc, a major signal-transducing protein in Escherichia coli. Proc Natl Acad Sci USA 86:4052-4055
37. Rephaeli AW, Saier MH Jr (1980) Regulation of Genes coding for enzyme constituents of the bacterial phosphotransferase system. J Bacteriol 141:658-663
38. Saier MH Jr, Roseman S (1976) Sugar transport The crr mutation: its effect on repression of the enzyme synthesis. J Biol Chem 251:6598-6605
39. Saier MH Jr, Simoni RD, Roseman S (1976) Sugar transport Properties of mutant bacteria defective in proteins of the phosphoenolpyruvate:sugar phosphotransferase system. J Biol Chem 251:6584-6597
40. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual (2nd edn). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
41. Glc of the phosphoenolpyruvate-dependent glucose phosphotransferase system of Salmonella typhimurium. J Baeteriol 148:257-264
42. fructose and fructose-induced HPr-like protein (FPr). Can J Biochcm 58:1144-1146
43. Wayne PK, Rosen OM (1974) Cyclic 3′:5′-adenosine monophosphate in Escherichia coli during transient and catabolite repression. Proc Natl Acad Sci USA 71:1436-1440
44. Winans ST, Elledge ST, Krueger JH, Walker G (1985) Site-directed insertion and deletion mutagenesis with cloned fragment in Escherichia coli. J Bacteriol 161:1219-1221
45. Wylic D, Stock A, Wong C.-Y. Stock J (1988) Sensory transduction in bacterial chemotaxis involves phosphotransfer between Che proteins. Biochem Biophys Res Commun 151:891-896