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Volumn 1, Issue 2, 1999, Pages 158-163

The epithelial sodium channel in hypertension

Author keywords

[No Author keywords available]

Indexed keywords

EPITHELIAL SODIUM CHANNEL; MINERALOCORTICOID; SCNN1B PROTEIN, HUMAN; SODIUM CHANNEL;

EID: 0033108030     PISSN: 15226417     EISSN: 15343111     Source Type: Journal    
DOI: 10.1007/s11906-999-0013-x     Document Type: Article
Times cited : (14)

References (43)
  • 1
    • 0001182641 scopus 로고
    • A familial renal disorder simulating primary aldosteronism but with negligible aldosterone secretion
    • Liddle GW, Bledsoe T, Coppage WS: A familial renal disorder simulating primary aldosteronism but with negligible aldosterone secretion. Trans Am Assoc Physicians 1963, 76:199-213.
    • (1963) Trans Am Assoc Physicians , vol.76 , pp. 199-213
    • Liddle, G.W.1    Bledsoe, T.2    Coppage, W.S.3
  • 3
    • 0031594450 scopus 로고    scopus 로고
    • Liddle syndrome: An autosomal dominant form of human hypertension
    • Warnock DG: Liddle syndrome: an autosomal dominant form of human hypertension. Kidney Intern 1998, 53:18-24. Detailed description of the clinical presentation and pathophysiologic basis for pseudoaldosteronism.
    • (1998) Kidney Intern , vol.53 , pp. 18-24
    • Warnock, D.G.1
  • 4
    • 0031157578 scopus 로고    scopus 로고
    • Cum grano salis: The epithelial sodium channel and the control of blood pressure
    • Rossier BC: Cum grano salis: the epithelial sodium channel and the control of blood pressure. J Amer Soc Nephrol 1997, 8:980-992. Homer Smith Lecture describing the expression cloning of ENaC and the genetic disorders of its regulation.
    • (1997) J Amer Soc Nephrol , vol.8 , pp. 980-992
    • Rossier, B.C.1
  • 5
    • 0027946089 scopus 로고
    • Liddle's syndrome: Heritable human hypertension caused by mutations in the b subunit of the epithelial sodium channel
    • Shimkets RA, Warnock DG, Bositis CM, et al.: Liddle's syndrome: heritable human hypertension caused by mutations in the b subunit of the epithelial sodium channel. Cell 1994, 79:407-414.
    • (1994) Cell , vol.79 , pp. 407-414
    • Shimkets, R.A.1    Warnock, D.G.2    Bositis, C.M.3
  • 6
    • 0029948974 scopus 로고    scopus 로고
    • Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle's syndrome
    • Schild L, Lu Y, Gautschi I, et al.: Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle's syndrome. EMBO J 1996, 15:2381-2387.
    • (1996) EMBO J , vol.15 , pp. 2381-2387
    • Schild, L.1    Lu, Y.2    Gautschi, I.3
  • 7
    • 0029874436 scopus 로고    scopus 로고
    • WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome
    • Staub O, Dho S, Henry PC, et al.: WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome. EMBO J 1996, 15:2371-2380.
    • (1996) EMBO J , vol.15 , pp. 2371-2380
    • Staub, O.1    Dho, S.2    Henry, P.C.3
  • 8
    • 0030731428 scopus 로고    scopus 로고
    • Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination
    • Staub O, Gautschi I, Ishikawa T, et al.: Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination. EMBO J 1997, 16:6325-6336. Cell biologic description of one pathway by which the expression of ENaC is controlled at the plasma membrane level.
    • (1997) EMBO J , vol.16 , pp. 6325-6336
    • Staub, O.1    Gautschi, I.2    Ishikawa, T.3
  • 9
    • 0029591506 scopus 로고
    • Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel
    • Snyder PM, Price M, McDonald FJ, et al.: Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel. Cell 1995, 83:969-978.
    • (1995) Cell , vol.83 , pp. 969-978
    • Snyder, P.M.1    Price, M.2    McDonald, F.J.3
  • 10
    • 0030451774 scopus 로고    scopus 로고
    • Cell surface expression of the epithelial Na channel and a mutatant causing Liddle syndrome: A quantitative approach
    • Firsov D, Schild L, Gautschi I, et al.: Cell surface expression of the epithelial Na channel and a mutatant causing Liddle syndrome: a quantitative approach. Proc Natl Acad Sci USA 1996, 93:15370-15375.
    • (1996) Proc Natl Acad Sci u S A , vol.93 , pp. 15370-15375
    • Firsov, D.1    Schild, L.2    Gautschi, I.3
  • 11
    • 0030820814 scopus 로고    scopus 로고
    • The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis
    • Shimkets RA, Lifton RP, Canessa CM: The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis. J Biol Chem 1997, 272:25537-25541.
    • (1997) J Biol Chem , vol.272 , pp. 25537-25541
    • Shimkets, R.A.1    Lifton, R.P.2    Canessa, C.M.3
  • 12
    • 0027414682 scopus 로고
    • Mass spectrometry in the diagnosis of steroidrelated disorders and in hypertension research
    • Shackleton CH: Mass spectrometry in the diagnosis of steroidrelated disorders and in hypertension research. J Steroid Biochem Molec Biol 1993, 45:127-140.
    • (1993) J Steroid Biochem Molec Biol , vol.45 , pp. 127-140
    • Shackleton, C.H.1
  • 13
    • 0030405694 scopus 로고    scopus 로고
    • Novel variant of the ßsubunit of the amiloride-sensitive sodium channel in African Americans
    • Su YR, Rutkowski MP, Klanke CA, et al.: novel variant of the ßsubunit of the amiloride-sensitive sodium channel in African Americans. J Am Soc Nephrol 1996, 7:2543-2549.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 2543-2549
    • Su, Y.R.1    Rutkowski, M.P.2    Klanke, C.A.3
  • 14
    • 0032499488 scopus 로고    scopus 로고
    • Association of hypertension with T594M mutation in the b subunit of epithelial sodium channels in black people resident in London
    • Baker EH, Dong YB, Sagnella GA, et al.: Association of hypertension with T594M mutation in the b subunit of epithelial sodium channels in black people resident in London. Lancet 1998, 351:1388-1392. Provocative report of polymorphisms in the ENaC beta subunit, and a genetic association to hypertension in blacks.
    • (1998) Lancet , vol.351 , pp. 1388-1392
    • Baker, E.H.1    Dong, Y.B.2    Sagnella, G.A.3
  • 15
    • 13344295074 scopus 로고    scopus 로고
    • Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1
    • Chang SS, Grunder S, Hanukoglu A, et al.: Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1. Nat Genet 1996, 12:248-253.
    • Nat Genet 1996 , vol.12 , pp. 248-253
    • Chang, S.S.1    Grunder, S.2    Hanukoglu, A.3
  • 16
    • 0030068042 scopus 로고    scopus 로고
    • A novel splice-site mutation in the gamma subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families
    • Strautnieks SS, Thompson RJ, Gardiner R. M, et al.: A novel splice-site mutation in the gamma subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families. Nat Genet 1996, 13:248-250.
    • (1996) Nat Genet , vol.13 , pp. 248-250
    • Strautnieks, S.S.1    Thompson, R.J.2    Gardiner, R.M.3
  • 17
    • 0031861245 scopus 로고    scopus 로고
    • Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism, type I
    • Geller DS, Rodriquez-Soriano J, Boado AV, et al.: Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism, type I. Nat Genet 1998, 19:279-281. Authoritative distinction between the dominant and recessive forms of pseudohypoaldosteronism, type I.
    • (1998) Nat Genet , vol.19 , pp. 279-281
    • Geller, D.S.1    Rodriquez-Soriano, J.2    Boado, A.V.3
  • 18
    • 0343247729 scopus 로고    scopus 로고
    • Pseudohypoaldosteronism due to renal and multisystem resistance to mineralocorticoids respond differently to carbenoxolone
    • Hanukoglu A, Joy O, Steinitz M, et al.: Pseudohypoaldosteronism due to renal and multisystem resistance to mineralocorticoids respond differently to carbenoxolone. J Steroid Biochem Molec Biol 1997, 60:105-112.
    • (1997) J Steroid Biochem Molec Biol , vol.60 , pp. 105-112
    • Hanukoglu, A.1    Joy, O.2    Steinitz, M.3
  • 19
    • 0029060080 scopus 로고
    • A mutation in the HSD11B2 gene in a family with apparent mineralocorticoid excess
    • Wilson RC, Krozowski ZS, Li K, et al.: A mutation in the HSD11B2 gene in a family with apparent mineralocorticoid excess. J Clin Endocrinol Metab 1995, 80:2263-2266.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2263-2266
    • Wilson, R.C.1    Krozowski, Z.S.2    Li, K.3
  • 20
    • 0029160972 scopus 로고
    • Human hypertension caused by mutations in the kidney isozyme of 11 betahydroxysteroid dehydrogenase
    • Mune T, Rogerson FM, Nikkila H, et al.: Human hypertension caused by mutations in the kidney isozyme of 11 betahydroxysteroid dehydrogenase. Nat Genet 1995, 10:394-399.
    • (1995) Nat Genet , vol.10 , pp. 394-399
    • Mune, T.1    Rogerson, F.M.2    Nikkila, H.3
  • 21
    • 0026441301 scopus 로고
    • Mineralocorticoid excess and inhibition of 11b-hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome
    • Walker BR, Campbell JC, Fraser R, et al.: Mineralocorticoid excess and inhibition of 11b-hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome. Clin Endocrinol 1992, 37:483-492.
    • (1992) Clin Endocrinol , vol.37 , pp. 483-492
    • Walker, B.R.1    Campbell, J.C.2    Fraser, R.3
  • 22
    • 0023743171 scopus 로고
    • Mineralocorticoid action: Target tissue specificity is enzyme, not receptor mediated
    • Funder JW, Pearce PT, Smith AT: Mineralocorticoid action: target tissue specificity is enzyme, not receptor mediated. Science 1987, 242:583-585.
    • (1987) Science , vol.242 , pp. 583-585
    • Funder, J.W.1    Pearce, P.T.2    Smith, A.T.3
  • 23
    • 0023242981 scopus 로고
    • Mineralocorticoid activity of liquorice: 11b-hydroxysteroid dehydrogenase deficiency comes of age
    • Stewart PM, Valentino R, Wallace AM, et al.: Mineralocorticoid activity of liquorice: 11b-hydroxysteroid dehydrogenase deficiency comes of age. Lancet 1987, 2:821-824.
    • (1987) Lancet , vol.2 , pp. 821-824
    • Stewart, P.M.1    Valentino, R.2    Wallace, A.M.3
  • 24
    • 0030598951 scopus 로고    scopus 로고
    • Naringin and naringenin are not the primary CYP3A inhibitors in grapefruit juice
    • Edwards DJ, Bernier SM: Naringin and naringenin are not the primary CYP3A inhibitors in grapefruit juice. Life Sci 1996, 59:1025-1030.
    • (1996) Life Sci , vol.59 , pp. 1025-1030
    • Edwards, D.J.1    Bernier, S.M.2
  • 25
    • 0030069526 scopus 로고    scopus 로고
    • Grapefruit juice and its flavinoids inhibit 11b-hydroxysteroid dehydrogenase
    • Lee YS, Lorenzo BJ, Koufis T, et al.: Grapefruit juice and its flavinoids inhibit 11b-hydroxysteroid dehydrogenase. Clin Pharmacol Ther 1996, 59:62-71.
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 62-71
    • Lee, Y.S.1    Lorenzo, B.J.2    Koufis, T.3
  • 26
    • 0025176537 scopus 로고
    • Mineralocorticoid activity of carbenoxolone: Contrasting effects of carbenoxolone and liquorice on 11b-hydroxysteroid dehydrogenase activity in man
    • Stewart PM, Atherden SM, Shearing CH, et al.: Mineralocorticoid activity of carbenoxolone: contrasting effects of carbenoxolone and liquorice on 11b-hydroxysteroid dehydrogenase activity in man. Clin Sci 1990, 78:49-54.
    • (1990) Clin Sci , vol.78 , pp. 49-54
    • Stewart, P.M.1    Atherden, S.M.2    Shearing, C.H.3
  • 27
    • 0029888213 scopus 로고    scopus 로고
    • Sodium status, corticosteroid metabolism and blood pressure in normal human subjects and in a patient with abnormal salt appetite
    • Ingram MC, Wallace AM, Collier A, et al.: Sodium status, corticosteroid metabolism and blood pressure in normal human subjects and in a patient with abnormal salt appetite. Clin Exp Pharmacol Physiol 1996, 23:375-378.
    • (1996) Clin Exp Pharmacol Physiol , vol.23 , pp. 375-378
    • Ingram, M.C.1    Wallace, A.M.2    Collier, A.3
  • 28
    • 0027320739 scopus 로고
    • Deficient inactivation of cortisol by 11b-hydroxysteroid dehydrogenase in essential hypertension
    • Walker BR, Stewart PM, Shackleton CHL, et al.: Deficient inactivation of cortisol by 11b-hydroxysteroid dehydrogenase in essential hypertension. Clin Endocrinol 1993, 39:221-227.
    • (1993) Clin Endocrinol , vol.39 , pp. 221-227
    • Walker, B.R.1    Stewart, P.M.2    Shackleton, C.H.L.3
  • 29
    • 0028967443 scopus 로고
    • Evidence of coexisting changes in 11b-hydroxysteroid dehydrogenase and 5b reductase activity in subjects with untreated essential hypertension
    • Soro A, Ingram MC, Tonolo G, et al.: Evidence of coexisting changes in 11b-hydroxysteroid dehydrogenase and 5b reductase activity in subjects with untreated essential hypertension. Hypertension 1995, 25:67-70.
    • (1995) Hypertension , vol.25 , pp. 67-70
    • Soro, A.1    Ingram, M.C.2    Tonolo, G.3
  • 30
    • 0008547265 scopus 로고    scopus 로고
    • Salt-sensitivity is associated with impaired 11b-hydroxy-steroid dehydrogenase type 2 activity in humans [abstract]
    • Dick B, Sharma AM Schorr U, et al.: Salt-sensitivity is associated with impaired 11b-hydroxy-steroid dehydrogenase type 2 activity in humans [abstract]. J Am Soc Nephrol 1998, 9:322. Preliminary report suggesting that there may be a genetic association between salt-sensitive hypertension and human 11b-hydroxy-steroid dehydrogenase, type 2 activity.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 322
    • Dick, B.1    Sharma, A.M.2    Schorr, U.3
  • 31
    • 0031723991 scopus 로고    scopus 로고
    • A new polymorphic restriction site in the human 11 beta-hydroxysteroid dehydrogenase type 2 gene
    • Smolenicka Z, Bach E, Schaer A, et al.: A new polymorphic restriction site in the human 11 beta-hydroxysteroid dehydrogenase type 2 gene. J Clin Endocrinol Metab 1998, 83:1814-1817. Simple bi-allelic polymorphism in an important candidate gene in human low renin hypertension.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1814-1817
    • Smolenicka, Z.1    Bach, E.2    Schaer, A.3
  • 32
    • 0347478279 scopus 로고    scopus 로고
    • Genetic Association of 11 beta-hydroxysteroid dehydrogenase type 2(HSD11B2) flanking microsatellites with essential hypertension in blacks
    • Watson BJ, Bergman SM, Myracle A, et al.: Genetic Association of 11 beta-hydroxysteroid dehydrogenase type 2(HSD11B2) flanking microsatellites with essential hypertension in blacks. Hypertension 1996, 28:478-482. Flanking microsatellites and allelic frequencies for an important candidate gene in blacks with low renin hypertension.
    • (1996) Hypertension , vol.28 , pp. 478-482
    • Watson, B.J.1    Bergman, S.M.2    Myracle, A.3
  • 33
    • 0026919361 scopus 로고
    • Hereditary hypertension caused by chimeric gene duplications and ectopic expression of aldosterone synthase
    • Lifton RP, Dluhy RG, Powers M, et al.: Hereditary hypertension caused by chimeric gene duplications and ectopic expression of aldosterone synthase. Nat Genet 1992, 2:66-74.
    • (1992) Nat Genet , vol.2 , pp. 66-74
    • Lifton, R.P.1    Dluhy, R.G.2    Powers, M.3
  • 34
    • 0026580019 scopus 로고
    • A chimaeric 11 b-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
    • Lifton RP, Dluhy RG, Powers M, et al.: A chimaeric 11 b-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature 1992, 355:262-265.
    • (1992) Nature , vol.355 , pp. 262-265
    • Lifton, R.P.1    Dluhy, R.G.2    Powers, M.3
  • 35
    • 0028883357 scopus 로고
    • Glucocorticoidsuppressible hyperaldosteronism and adrenal tumors occurring in a single French pedigree
    • Pascoe L, Jeunemaitre X, Lebrethon M-C, et al.: Glucocorticoidsuppressible hyperaldosteronism and adrenal tumors occurring in a single French pedigree. J Clin Invest 1995, 96:2236-2246.
    • (1995) J Clin Invest , vol.96 , pp. 2236-2246
    • Pascoe, L.1    Jeunemaitre, X.2    Lebrethon, M.-C.3
  • 36
    • 0027052962 scopus 로고
    • Glucocorticoid-remediable aldosteronism in a large kindred: Clinical spectrum and diagnosis using a characteristic biochemical phenotype
    • Rich G, Ulick S, Cook S, et al.: Glucocorticoid-remediable aldosteronism in a large kindred: clinical spectrum and diagnosis using a characteristic biochemical phenotype. Ann Int Med 1992, 116:813-820.
    • (1992) Ann Int Med , vol.116 , pp. 813-820
    • Rich, G.1    Ulick, S.2    Cook, S.3
  • 37
    • 0030465271 scopus 로고    scopus 로고
    • 11b-hydroxylase activity in glucocorticoid suppressible hyperaldosteronism: Lessons for essential hypertension
    • Connell JMC, Jamieson AJ, Davies E, et al.: 11b-hydroxylase activity in glucocorticoid suppressible hyperaldosteronism: lessons for essential hypertension. Endocrinol Res 1996, 22:691-700.
    • (1996) Endocrinol Res , vol.22 , pp. 691-700
    • Connell, J.M.C.1    Jamieson, A.J.2    Davies, E.3
  • 38
    • 0029847663 scopus 로고    scopus 로고
    • Inherited forms of mineralocorticoid hypertension
    • White PC: Inherited forms of mineralocorticoid hypertension. Hypertension 1996, 28:927-936.
    • (1996) Hypertension , vol.28 , pp. 927-936
    • White, P.C.1
  • 39
    • 0025729737 scopus 로고
    • Inappropriate elevation of the aldosterone/plasma renin activity ratio in hypertensive patients and 18-hydroxy-11-deoxycorticosterone: A subtype of essential hypertension?
    • Komiya I, Yamada T, Aizawa T, et al.: Inappropriate elevation of the aldosterone/plasma renin activity ratio in hypertensive patients and 18-hydroxy-11-deoxycorticosterone: a subtype of essential hypertension? Cardiology 1991, 78:99-110.
    • (1991) Cardiology , vol.78 , pp. 99-110
    • Komiya, I.1    Yamada, T.2    Aizawa, T.3
  • 40
    • 0030068024 scopus 로고    scopus 로고
    • Molecular genetics of human blood pressure variation
    • Lifton RP: Molecular genetics of human blood pressure variation. Science 1996, 272:676-680.
    • (1996) Science , vol.272 , pp. 676-680
    • Lifton, R.P.1
  • 41
    • 0029799269 scopus 로고    scopus 로고
    • Molecular biology of mineralocorticoid metabolism
    • Fardella CE, Miller WL: Molecular biology of mineralocorticoid metabolism. Ann Rev Nutr 1996, 16:443-470.
    • (1996) Ann Rev Nutr , vol.16 , pp. 443-470
    • Fardella, C.E.1    Miller, W.L.2
  • 42
    • 0028939142 scopus 로고
    • Primary aldosteronism
    • Holland OB: Primary aldosteronism. Semin Nephrol 1995, 15:116-125.
    • (1995) Semin Nephrol , vol.15 , pp. 116-125
    • Holland, O.B.1
  • 43
    • 0029890003 scopus 로고    scopus 로고
    • Altered 11b-hydroxylase activity in glucocorticoid-suppressible hyperaldosteronism
    • Jamieson A, Ingram, MC, Inglis, GC, et al.: Altered 11b-hydroxylase activity in glucocorticoid-suppressible hyperaldosteronism. J Clin Endocrinol Metab 1996, 81:2298-2302.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2298-2302
    • Jamieson, A.1    Ingram, M.C.2    Inglis, G.C.3


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