Sequence-specific DNA alkylation by hybrid molecules between segment A of duocarmycin A and pyrrole/imidazole diamide

Angewandte Chemie - International Edition

Volumn 38, Issue 5, 1999, Pages 650-653

  Tao, Zhi Fu ^b,c   Fujiwara, Tsuyoshi ^b,c   Saito, Isao ^a,b   Sugiyama, Hiroshi ^b,c  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Alkylations; Antibiotics; Antitumor agents; DNA cleavage; DNA recognition

Indexed keywords

DISTAMYCIN A; DNA ALKYLATION; DUOCARMYCIN A; HYBRID MOLECULE; IMIDAZOLE DIAMIDE; PYRROLE; SEQUENCE ANALYSIS;

DIAMIDE; DNA FRAGMENT; DNA HYBRID; DUOCARMYCIN A; IMIDAZOLE DERIVATIVE; PYRROLE;

ARTICLE; BINDING AFFINITY; DIMERIZATION; DNA ALKYLATION; DNA BINDING; DNA CLEAVAGE; DNA HYBRIDIZATION; DNA SEQUENCE; DRUG STRUCTURE; HYDROLYSIS; MASS SPECTROMETRY; REACTION ANALYSIS;

EID: 0033105645     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19990301)38:5<650::AID-ANIE650>3.0.CO;2-O     Document Type: Article

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