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Volumn 288, Issue 2, 1999, Pages 798-804

Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; APOMORPHINE; BRIMONIDINE; CLONIDINE; EFAROXAN; IDAZOXAN; METHYLPHENIDATE; OXIDOPAMINE;

EID: 0033064450     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (67)

References (70)
  • 1
    • 0012287302 scopus 로고
    • Norepinephrine-dopamine interactions: One step beyond
    • (Briley M and Marien M eds) CRC Press, Boca Raton
    • Antelman SM and Caggiula AR (1994) Norepinephrine-dopamine interactions: One step beyond, in Noradrenergic Mechanisms in Parkinson's Disease (Briley M and Marien M eds) pp 127-138, CRC Press, Boca Raton.
    • (1994) Noradrenergic Mechanisms in Parkinson's Disease , pp. 127-138
    • Antelman, S.M.1    Caggiula, A.R.2
  • 2
    • 0023712513 scopus 로고
    • Unique presynaptic alpha-2 receptor selectivity and specificity of the antihypertensive agent moxonidine
    • Armah BI (1988) Unique presynaptic alpha-2 receptor selectivity and specificity of the antihypertensive agent moxonidine. Arzneim Forsch 38:1435-1442.
    • (1988) Arzneim Forsch , vol.38 , pp. 1435-1442
    • Armah, B.I.1
  • 3
    • 0001503503 scopus 로고
    • Behavioural studies of dopamine receptors: Evidence for regional selectivity and receptor multiplicity
    • (Creese I and Fraser CA eds) Alan Liss, New York
    • Arnt J (1987) Behavioural studies of dopamine receptors: Evidence for regional selectivity and receptor multiplicity, in Dopamine Receptors (Creese I and Fraser CA eds) pp 199-231, Alan Liss, New York.
    • (1987) Dopamine Receptors , pp. 199-231
    • Arnt, J.1
  • 4
    • 0030174951 scopus 로고    scopus 로고
    • 2-Adrenergic agonists reduce glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices during hypoxia
    • 2-Adrenergic agonists reduce glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices during hypoxia. Neuropharmacology 35: 679-687.
    • (1996) Neuropharmacology , vol.35 , pp. 679-687
    • Bickler, P.E.1    Hansen, B.M.2
  • 6
    • 0029116016 scopus 로고
    • Pharmacological characteristics of alpha-2 adrenergic receptor subtypes
    • Bylund DB (1995) Pharmacological characteristics of alpha-2 adrenergic receptor subtypes. Ann NY Acad Sci 763:1-7.
    • (1995) Ann NY Acad Sci , vol.763 , pp. 1-7
    • Bylund, D.B.1
  • 7
    • 0027081142 scopus 로고
    • Pharmacological characteristics of alpha-2 adrenergic receptors: Comparison of pharmacologically defined subtypes with subtypes identified with molecular cloning
    • Bylund DB, Blaxall HS, Iversen LJ, Caron MG, Lefkpwitz RJ and Lomasney JW (1992) Pharmacological characteristics of alpha-2 adrenergic receptors: Comparison of pharmacologically defined subtypes with subtypes identified with molecular cloning. Mol Pharmacol 42:1-5.
    • (1992) Mol Pharmacol , vol.42 , pp. 1-5
    • Bylund, D.B.1    Blaxall, H.S.2    Iversen, L.J.3    Caron, M.G.4    Lefkpwitz, R.J.5    Lomasney, J.W.6
  • 8
    • 0029025911 scopus 로고
    • Efaroxan acts peripherally to block the antisecretory and gastroprotective effects of moxonidine in rats
    • Carlisle MA, Smyth DD and Glavin GB (1995) Efaroxan acts peripherally to block the antisecretory and gastroprotective effects of moxonidine in rats. J Pharmacol Exp Ther 274:598-601.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 598-601
    • Carlisle, M.A.1    Smyth, D.D.2    Glavin, G.B.3
  • 9
    • 0025818117 scopus 로고
    • Partial lesion of the substantia nigra: Relation between extent of lesion and rotational behavior
    • Carman LS, Gage FH and Shults CW (1991) Partial lesion of the substantia nigra: Relation between extent of lesion and rotational behavior. Brain Res 553:275-283.
    • (1991) Brain Res , vol.553 , pp. 275-283
    • Carman, L.S.1    Gage, F.H.2    Shults, C.W.3
  • 10
    • 0021682595 scopus 로고
    • Adrenergic receptors in Parkinson's disease
    • Cash R, Ruberg M, Raisman R and Agid Y (1984) Adrenergic receptors in Parkinson's disease. Brain Res 322:269-275.
    • (1984) Brain Res , vol.322 , pp. 269-275
    • Cash, R.1    Ruberg, M.2    Raisman, R.3    Agid, Y.4
  • 11
    • 0018471789 scopus 로고
    • Neurochemical and electrophysiological evidence for a projection from the locus coeruleus to the substantia nigra
    • Collingridge GL, James TA and MacCleod NK (1979) Neurochemical and electrophysiological evidence for a projection from the locus coeruleus to the substantia nigra. J Physiol 290:44.
    • (1979) J Physiol , vol.290 , pp. 44
    • Collingridge, G.L.1    James, T.A.2    MacCleod, N.K.3
  • 12
    • 0022588764 scopus 로고
    • Effects of putative α-adrenoceptor antagonists and of other compounds on the loss of the righting reflex and on exophthalmia induced by xylazine in the rat
    • Colpaert FC (1986a) Effects of putative α-adrenoceptor antagonists and of other compounds on the loss of the righting reflex and on exophthalmia induced by xylazine in the rat. Drug Dev Res 7:125-140.
    • (1986) Drug Dev Res , vol.7 , pp. 125-140
    • Colpaert, F.C.1
  • 13
    • 0022569636 scopus 로고
    • Maximal magnitude of effect and potency of putative α-adrenoceptor agonists in causing CNS depression, in relaxing muscle and in lowering body temperature in rat
    • Colpaert FC (1986b) Maximal magnitude of effect and potency of putative α-adrenoceptor agonists in causing CNS depression, in relaxing muscle and in lowering body temperature in rat. Drug Dev Res 7:209-220.
    • (1986) Drug Dev Res , vol.7 , pp. 209-220
    • Colpaert, F.C.1
  • 14
    • 0023241854 scopus 로고
    • Pharmacological characteristics of tremor, rigidity and hypokinesia induced by reserpine in rat
    • Colpaert FC (1987) Pharmacological characteristics of tremor, rigidity and hypokinesia induced by reserpine in rat. Neuropharmacology 26:1431-1440.
    • (1987) Neuropharmacology , vol.26 , pp. 1431-1440
    • Colpaert, F.C.1
  • 15
    • 0002181891 scopus 로고
    • Noradrenergic mechanisms in Parkinson's disease: A theory
    • (Briley M and Marien M eds) CRC Press, Boca Raton
    • Colpaert FC (1994) Noradrenergic mechanisms in Parkinson's disease: A theory, in Noradrenergic Mechanisms in Parkinson's Disease (Briley M and Marien M eds) pp 127-138, CRC Press, Boca Raton.
    • (1994) Noradrenergic Mechanisms in Parkinson's Disease , pp. 127-138
    • Colpaert, F.C.1
  • 17
    • 0016611343 scopus 로고
    • A comparison of circling models for the detection of antiparkinson activity
    • Costall B and Naylor RJ (1975) A comparison of circling models for the detection of antiparkinson activity. Psychopharmacologia 41:57-64.
    • (1975) Psychopharmacologia , vol.41 , pp. 57-64
    • Costall, B.1    Naylor, R.J.2
  • 18
    • 0018581328 scopus 로고
    • Depression of exploratory activity of clonidine in rats as a model for the detection of relative pre- and post-synaptic central noradrenergic receptor selectivity of α-adrenolytic drugs
    • Delina-Stula A, Baumann P and Buch O (1979) Depression of exploratory activity of clonidine in rats as a model for the detection of relative pre- and post-synaptic central noradrenergic receptor selectivity of α-adrenolytic drugs. Naunyn-Schmiedeberg's Arch Pharmacol 307:115-122.
    • (1979) Naunyn-schmiedeberg's Arch Pharmacol , vol.307 , pp. 115-122
    • Delina-Stula, A.1    Baumann, P.2    Buch, O.3
  • 19
    • 0026025425 scopus 로고
    • Efaroxan (RX 821037) is a potent and selective alpha2-adrenoceptor antagonist in human frontal cortex membranes
    • De Vos H, De Backer JP and Vauquelin G (1991) Efaroxan (RX 821037) is a potent and selective alpha2-adrenoceptor antagonist in human frontal cortex membranes. Neurochem Int 18:137-140.
    • (1991) Neurochem Int , vol.18 , pp. 137-140
    • De Vos, H.1    De Backer, J.P.2    Vauquelin, G.3
  • 20
    • 0018099290 scopus 로고
    • Catecholamine innervation of the basal forebrain. IV. Topography of the dopamine projection to the basal forebrain and neostriatum
    • Fallon SH and Moore RY (1978) Catecholamine innervation of the basal forebrain. IV. Topography of the dopamine projection to the basal forebrain and neostriatum. J Comp Neurol 180:545-580.
    • (1978) J Comp Neurol , vol.180 , pp. 545-580
    • Fallon, S.H.1    Moore, R.Y.2
  • 21
    • 0030614875 scopus 로고    scopus 로고
    • Pharmacological characterization of I1 and I2 imidazoline receptors in human striatum
    • Flamez A, De Backer JP, Czerwiec E, Ladure P and Vauquelin G (1997) Pharmacological characterization of I1 and I2 imidazoline receptors in human striatum. Neurochem Int 30:25-29.
    • (1997) Neurochem Int , vol.30 , pp. 25-29
    • Flamez, A.1    De Backer, J.P.2    Czerwiec, E.3    Ladure, P.4    Vauquelin, G.5
  • 22
    • 0022259454 scopus 로고
    • Regional brain dopamine metabolism: A marker for the speed, direction and posture of moving animals
    • Freed CR and Yamamoto BK (1985) Regional brain dopamine metabolism: A marker for the speed, direction and posture of moving animals. Science 229:62-65.
    • (1985) Science , vol.229 , pp. 62-65
    • Freed, C.R.1    Yamamoto, B.K.2
  • 24
    • 0029845140 scopus 로고    scopus 로고
    • Animal models of Parkinson's disease: An empirical comparison with the phenomenology of the disease in man
    • Gerlach M and Riederer P (1996) Animal models of Parkinson's disease: An empirical comparison with the phenomenology of the disease in man. J Neural Transm 103:987-1041.
    • (1996) J Neural Transm , vol.103 , pp. 987-1041
    • Gerlach, M.1    Riederer, P.2
  • 25
    • 0019124026 scopus 로고
    • Interaction of selective α-adrenoceptor agonists and antagonists with human and rabbit blood platelets
    • Grant JA and Scrutton MC (1980) Interaction of selective α-adrenoceptor agonists and antagonists with human and rabbit blood platelets. Br J Pharmacol 71:121-134.
    • (1980) Br J Pharmacol , vol.71 , pp. 121-134
    • Grant, J.A.1    Scrutton, M.C.2
  • 26
    • 0023910816 scopus 로고
    • Clonidine regularizes substantia nigra dopamine cell firing
    • Grenhoff J and Svensson TH (1988) Clonidine regularizes substantia nigra dopamine cell firing. Life Sci 42:2003-2009.
    • (1988) Life Sci , vol.42 , pp. 2003-2009
    • Grenhoff, J.1    Svensson, T.H.2
  • 27
    • 0016195717 scopus 로고
    • Clonidine-induced inhibition of sympathetic nerve activity: No indication for a central presynaptic or an indirect sympathomimetic mode of action
    • Haeusler G (1974) Clonidine-induced inhibition of sympathetic nerve activity: No indication for a central presynaptic or an indirect sympathomimetic mode of action. Naunyn-Schmiedeberg's Arch Pharmacol 286:97-111.
    • (1974) Naunyn-Schmiedeberg's Arch Pharmacol , vol.286 , pp. 97-111
    • Haeusler, G.1
  • 28
    • 0030911562 scopus 로고    scopus 로고
    • Risperidone dose-dependently increases extracellular concentrations of serotonin in the rat frontal cortex: Role of α2-adrenoceptor antagonism
    • Hertel P, Nomikos GG, Schilström B, Arborelius L and Svensson TH (1997) Risperidone dose-dependently increases extracellular concentrations of serotonin in the rat frontal cortex: Role of α2-adrenoceptor antagonism. Neuropsychopharmacology 17:44-55.
    • (1997) Neuropsychopharmacology , vol.17 , pp. 44-55
    • Hertel, P.1    Nomikos, G.G.2    Schilström, B.3    Arborelius, L.4    Svensson, T.H.5
  • 29
    • 0020028422 scopus 로고
    • Reduction in DA utilization in the prefrontal cortex but not in the nucleus accumbens after selective destruction of noradrenergic fibers innervating the ventral tegmental area in the rat
    • Hervé D, Blanc G, Glowinski J and Tassin JP (1982) Reduction in DA utilization in the prefrontal cortex but not in the nucleus accumbens after selective destruction of noradrenergic fibers innervating the ventral tegmental area in the rat. Brain Res 237:510-516.
    • (1982) Brain Res , vol.237 , pp. 510-516
    • Hervé, D.1    Blanc, G.2    Glowinski, J.3    Tassin, J.P.4
  • 30
    • 0023263919 scopus 로고
    • Biochemical pathophysiology in Parkinson's disease
    • Hornykiewicz O and Kish SJ (1986) Biochemical pathophysiology in Parkinson's disease. Adv Neurol 45:19-34.
    • (1986) Adv Neurol , vol.45 , pp. 19-34
    • Hornykiewicz, O.1    Kish, S.J.2
  • 31
    • 0027449341 scopus 로고
    • Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats
    • Hudson JL, van Horne CG, Strömberg I, Brock S, Clayton J, Masserano J, Hoffer BJ and Gerhardt GA (1993) Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats. Brain Res 626:167-174.
    • (1993) Brain Res , vol.626 , pp. 167-174
    • Hudson, J.L.1    Van Horne, C.G.2    Strömberg, I.3    Brock, S.4    Clayton, J.5    Masserano, J.6    Hoffer, B.J.7    Gerhardt, G.A.8
  • 32
    • 0017576266 scopus 로고
    • Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study
    • Jones BA and Moore RY (1977) Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study. Brain Res 127:23-53.
    • (1977) Brain Res , vol.127 , pp. 23-53
    • Jones, B.A.1    Moore, R.Y.2
  • 33
  • 34
    • 0018743309 scopus 로고
    • Origin and organisation of brainstem catecholamine innervation in the rat
    • Levitt P and Moore RY (1979) Origin and organisation of brainstem catecholamine innervation in the rat. J Camp Neurol 186:505-528.
    • (1979) J Camp Neurol , vol.186 , pp. 505-528
    • Levitt, P.1    Moore, R.Y.2
  • 35
    • 0000817571 scopus 로고
    • Noradrenergic control of striatal dopamine release
    • (Briley M and Marien M eds) CRC Press, Boca Raton
    • Marien M, Lategan A and Colpaert FC (1994) Noradrenergic control of striatal dopamine release, in Noradrenergic Mechanisms in Parkinson's Disease (Briley M and Marien M eds) pp127-138, CRC Press, Boca Raton.
    • (1994) Noradrenergic Mechanisms in Parkinson's Disease , pp. 127-138
    • Marien, M.1    Lategan, A.2    Colpaert, F.C.3
  • 36
    • 0344620885 scopus 로고    scopus 로고
    • 2-adrenoceptor antagonists (+)-efaroxan and (±)-idazoxan on quinolinic acid-induced lesions of the rat striatum
    • 2-adrenoceptor antagonists (+)-efaroxan and (±)-idazoxan on quinolinic acid-induced lesions of the rat striatum. Soc Neurosci Abst 22:1908.
    • (1996) Soc Neurosci Abst , vol.22 , pp. 1908
    • Martel, J.C.1    Chopin, P.2    Colpaert, F.C.3    Marien, M.4
  • 38
    • 0025853857 scopus 로고
    • Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in monkeys: A possible role for the locus coeruleus in the progression of Parkinson's disease
    • Mavridis M, Degryse AD, Lategan AJ, Marien M and Colpaert FC (1991b) Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in monkeys: A possible role for the locus coeruleus in the progression of Parkinson's disease. Neuroscience 41:507-523.
    • (1991) Neuroscience , vol.41 , pp. 507-523
    • Mavridis, M.1    Degryse, A.D.2    Lategan, A.J.3    Marien, M.4    Colpaert, F.C.5
  • 39
    • 0001817743 scopus 로고
    • CNS stimulants: Two distinct mechanisms of action for amphetamine-like drugs
    • McMillen BA (1983) CNS stimulants: Two distinct mechanisms of action for amphetamine-like drugs. Trends Pharmacol Sci 9:429-432.
    • (1983) Trends Pharmacol Sci , vol.9 , pp. 429-432
    • McMillen, B.A.1
  • 40
    • 0018270904 scopus 로고
    • Partial agonist action of clonidine on prejunctional and postjunctional alpha-adrenoceptors
    • Medgett IC, McCulloch MW and Rand MJ (1978) Partial agonist action of clonidine on prejunctional and postjunctional alpha-adrenoceptors. Naunyn-Schmiedeberg's Arch Pharmacol 304:215-221.
    • (1978) Naunyn-Schmiedeberg's Arch Pharmacol , vol.304 , pp. 215-221
    • Medgett, I.C.1    McCulloch, M.W.2    Rand, M.J.3
  • 44
    • 0021033877 scopus 로고
    • Modulation of cortical acetylcholine and γ-aminobutyric acid release in freely moving guinea pigs: Effects of clonidine and other adrenergic drugs
    • Moroni F, Tanganelli S, Antonelli T, Carla V, Bianchi C and Beani L (1983) Modulation of cortical acetylcholine and γ-aminobutyric acid release in freely moving guinea pigs: Effects of clonidine and other adrenergic drugs. J Pharmacol Exp Ther 227:435-440.
    • (1983) J Pharmacol Exp Ther , vol.227 , pp. 435-440
    • Moroni, F.1    Tanganelli, S.2    Antonelli, T.3    Carla, V.4    Bianchi, C.5    Beani, L.6
  • 46
    • 0002362332 scopus 로고
    • 2-adrenoceptor antagonists on extracellular dopamine concentrations in rat striatum
    • (Briley M and Marien M eds) CRC Press, Boca Raton
    • 2-adrenoceptor antagonists on extracellular dopamine concentrations in rat striatum, in Noradrenergic Mechanisms in Parkinson's Disease (Briley M and Marien M eds) pp 127-138, CRC Press, Boca Raton.
    • (1994) Noradrenergic Mechanisms in Parkinson's Disease , pp. 127-138
    • Nutt, D.1    Lalies, M.2    Hudson, A.3
  • 48
    • 0021918716 scopus 로고
    • Are the anxiogenic effects of yohimbine mediated by its action at benzodiazepine receptors?
    • Pellow S, Chopin P and File SE (1985) Are the anxiogenic effects of yohimbine mediated by its action at benzodiazepine receptors? Neurosci Lett 55:5-9.
    • (1985) Neurosci Lett , vol.55 , pp. 5-9
    • Pellow, S.1    Chopin, P.2    File, S.E.3
  • 51
    • 0018903301 scopus 로고
    • Turning behavior in animals
    • Pycock CJ (1980) Turning behavior in animals. Neuroscience 5:461-514.
    • (1980) Neuroscience , vol.5 , pp. 461-514
    • Pycock, C.J.1
  • 54
  • 56
    • 0030272769 scopus 로고    scopus 로고
    • The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments
    • Schwarting RKW and Husten JP (1996) The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments. Prog Neurobiol. 50:275-331.
    • (1996) Prog Neurobiol. , vol.50 , pp. 275-331
    • Schwarting, R.K.W.1    Husten, J.P.2
  • 57
    • 0027328278 scopus 로고
    • On-off effects of dopamine receptor agonists in the hemiparkinsonian rat
    • Silverman PB (1993) On-off effects of dopamine receptor agonists in the hemiparkinsonian rat. Eur J Pharmacol 242:31-36.
    • (1993) Eur J Pharmacol , vol.242 , pp. 31-36
    • Silverman, P.B.1
  • 58
    • 0029936117 scopus 로고    scopus 로고
    • Dopaminergic systems and Parkinson's disease: Some latest developments in pathogenetic, diagnostic and pharmacotherapeutic investigations
    • Stoof JC, Vermeulen RJ, Van Royen EA, Drukarch B, Voorn P, Wolters EC and Groenewegen HJ (1996) Dopaminergic systems and Parkinson's disease: Some latest developments in pathogenetic, diagnostic and pharmacotherapeutic investigations. Neurosci Res 18:133-142.
    • (1996) Neurosci Res , vol.18 , pp. 133-142
    • Stoof, J.C.1    Vermeulen, R.J.2    Van Royen, E.A.3    Drukarch, B.4    Voorn, P.5    Wolters, E.C.6    Groenewegen, H.J.7
  • 59
    • 0029089219 scopus 로고
    • Crucial role of the accumbens nucleus in the neurotransmitter interactions regulating motor control in mice
    • Svensson A, Carlsson ML and Carlsson A (1995) Crucial role of the accumbens nucleus in the neurotransmitter interactions regulating motor control in mice. J Neural Transm 101:127-148.
    • (1995) J Neural Transm , vol.101 , pp. 127-148
    • Svensson, A.1    Carlsson, M.L.2    Carlsson, A.3
  • 60
    • 0025821574 scopus 로고
    • Suppression of noradrenergic innervation compensates for behavioral deficits induced by lesion of dopaminergic terminals in the lateral septum
    • Taghzouti K, Le Moal M and Simon H (1991) Suppression of noradrenergic innervation compensates for behavioral deficits induced by lesion of dopaminergic terminals in the lateral septum. Brain Res 552:124-128.
    • (1991) Brain Res , vol.552 , pp. 124-128
    • Taghzouti, K.1    Le Moal, M.2    Simon, H.3
  • 61
    • 0012595322 scopus 로고
    • Interactions between noradrenaline and dopamine neurotransmission in the rat prefrontal cortex and their consequences on dopaminergic subcortical function
    • (Briley M and Marien M eds) CRC Press, Boca Raton
    • Taasin JP, Trovero F, Blanc G, Hervé D and Glowinski J (1994) Interactions between noradrenaline and dopamine neurotransmission in the rat prefrontal cortex and their consequences on dopaminergic subcortical function, in Noradrenergic Mechanisms in Parkinson's Disease (Briley M and Marien M eds) pp107-125, CRC Press, Boca Raton.
    • (1994) Noradrenergic Mechanisms in Parkinson's Disease , pp. 107-125
    • Taasin, J.P.1    Trovero, F.2    Blanc, G.3    Hervé, D.4    Glowinski, J.5
  • 62
    • 0028987304 scopus 로고
    • 2-adrenoceptor antagonist, (+)-efaroxan, enhances acetylcholine release in the rat cortex in vivo
    • 2-adrenoceptor antagonist, (+)-efaroxan, enhances acetylcholine release in the rat cortex in vivo. Eur J Pharmacol 277:113-116.
    • (1995) Eur J Pharmacol , vol.277 , pp. 113-116
    • Tellez, S.1    Colpaert, F.C.2    Marien, M.3
  • 64
    • 0015184103 scopus 로고
    • Post-synaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigrostriatal dopamine system
    • Ungerstedt U (1971) Post-synaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigrostriatal dopamine system. Acta Physiol Scand 367:69-93.
    • (1971) Acta Physiol Scand , vol.367 , pp. 69-93
    • Ungerstedt, U.1
  • 65
    • 0021396341 scopus 로고
    • 2-agonist binding sites in the rat and human central nervous system: Analysis of some functional and anatomic correlates of the pharmacological effects of clonidine and related adrenergic agents
    • 2-agonist binding sites in the rat and human central nervous system: Analysis of some functional and anatomic correlates of the pharmacological effects of clonidine and related adrenergic agents. Brain Res Rev 69:69-86.
    • (1984) Brain Res Rev , vol.69 , pp. 69-86
    • Unnerstall, J.R.1    Kopajtic, T.A.2    Kuhar, M.J.3
  • 67
    • 0026089486 scopus 로고
    • Medetomidine stereoisomers delineate two closely related subtypes of idazoxan (imidazoline) I-receptors in the guinea-pig
    • Wikberg JES, Uhlen S and Chhajlani V (1991) Medetomidine stereoisomers delineate two closely related subtypes of idazoxan (imidazoline) I-receptors in the guinea-pig. Eur J Pharmacol 193:335-340.
    • (1991) Eur J Pharmacol , vol.193 , pp. 335-340
    • Wikberg, J.E.S.1    Uhlen, S.2    Chhajlani, V.3


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