Effects of endothelial and inducible nitric oxide synthases inhibition on circulatory function in rats after myocardial infarction

Cardiovascular Research

Volumn 42, Issue 3, 1999, Pages 627-635

  Gaballa, Mohamed A ^a   Raya, Thomas E ^a   Hoover, Craig A ^a   Goldman, Steven ^a  

^a SOUTHERN ARIZONA VA HEALTH CARE SYSTEM   (United States)

Author keywords

Adrenergic receptors; Blood flow; Heart failure; Nitric oxide

Indexed keywords

AMINOGUANIDINE; BETA ADRENERGIC RECEPTOR; ISOPRENALINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA FLOW; ARTICLE; BLOOD FLOW VELOCITY; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; HEART INFARCTION; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART RATE; HEMODYNAMICS; IMPEDANCE; INTRAVENOUS DRUG ADMINISTRATION; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; SYSTEMIC VASCULAR RESISTANCE;

ADRENERGIC BETA-AGONISTS; ANALYSIS OF VARIANCE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GUANIDINES; HEMODYNAMIC PROCESSES; ISOPROTERENOL; MYOCARDIAL INFARCTION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0033057776     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(98)00343-5     Document Type: Article

References (25)

1. Kiuchi K., Sato N., Shannon R.P., Vatner D.E., Morgan K., Vatner S.F. Depressed beta-adrenergic receptor- and endothelium-mediated vasodilation in conscious dogs with heart failure. Circ Res. 73:1993;1013-1023.
2. Takeshita A., Hirooka Y., Imaizumi T. Role of the endothelium in control of forearm blood flow in patients with heart failure. J Cardiac Failure. 2(4S):1996;S209-S215.
3. Kubo S.H., Rector T.S., Bank A.J. Endothelial nitric oxide pathway function in the peripheral vasculature of patients with heart failure. J Cardiac Failure. 2(4S):1996;S217-S223.
4. Ontkean M., Gay R., Greenberg B. Diminished endothelium derived relaxing factor activity in an experimental model of chronic heart failure. Circ Res. 69:1991;1088-1096.
5. Balligand J.L., Kelly R.A., Marsden P.A., Smith T.W., Michel T. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci USA. 90:1993;347-351.
6. Kelly R.A., Balligand J.L., Smith T.W. Nitric oxide and cardiac function. Circ Res. 79:1996;363-380.
7. Chen H., Hu C. Endogenous nitric oxide on arterial hemodynamics, a comparison between normotensive and hypertensive rats. Am J Physiol. 273:1997;H1816-1823.
8. Rademaker M.T., Fitzpatrick M.A., Richards A.M.et al. Nitric oxide inhibition in an ovine model of heart failure. Clin Exp Pharmacol Physiol. 23:1996;403-409.
9. Wildhirt S.M., Suzuki H., Horstman D.et al. Selective modulation of inducible nitric oxide synthase isozyme in myocardial infarction. Circulation. 96:1997;1616-1623.
10. Gaballa M., Raya T.E., Goldman S. Large artery remodeling after myocardial infarction. Am J Physiol. 268:1995;H2092-H2103.
11. Pfeffer M.A., Pfeffer J.M., Steinberg C. Finn Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril. Circulation. 72:1985;406-412.
12. Raya T.E., Gay R.G., Aguirre M., Goldman S. The importance of venodilation in the prevention of left ventricular dilatation after chronic large myocardial infarction in rats: a comparison of captopril and hydralazine. Circ Res. 64:1989;330-338.
13. Gay R.G., Wool S., Paquin M., Goldman S. Total vascular pressure-volume relationship in conscious rats with chronic heart failure. Am J Physiol. 251:1986;H341-H346.
14. Ma X., Lopez B.L., Christopher T.A., Birenbaum D.S., Vinten-Johansen J. Exogenous NO inhibits basal NO release from vascular endothelium in vitro and in vivo. Am J Physiol. 271:1996;H2045-H2051.
15. Loeb A.L., Longnecker D.E. Inhibition of endothelium-derived relaxing factor-dependent circulatory control in intact rats. Am J Physiol. 262:1992;H1494-H1500.
16. Chu A., Chambers D.E., Lin C.C., Kuehl W.D., Palmer R.M. Effects of inhibition of nitric oxide formation on basal vasomotion and endothelium-dependent responses of the coronary arteries in awake dogs. J Clin Invest. 87:1991;1964-1968.
17. Granger J., Novak J., Schnackenberg C., Williams S., Reinhart G.A. Role of renal nerves in mediating the hypertensive effects of nitric oxide synthesis inhibition. Hypertension. 27(part 2):1996;613-618.
18. Milnor WR. Hemodynamics. Baltimore, MD: Williams and Wilkins, 1982:Chap. 7;157-191.
19. Keaney J.F., Hare J.M., Balligand J.L., Loscalzo J., Smith T.W., Colucci W.S. Inhibition of nitric oxide synthase augments myocardial contractile responses to β-adrenergic stimulation. Am J Physiol. 271:1996;H2646-H2652.
20. Sherman A.J., Davis III C.A., Klocke F.J.et al. Blockade of nitric oxide synthesis reduces myocardial oxygen consumption in vivo. Circulation. 95:1997;1328-1334.
21. Kaneko H., Endo T., Kiuchi K., Hayakawa H. Inhibition of nitric oxide synthesis reduces coronary blood flow response but does not increase cardiac contractile response to β-adrenergic stimulation in normal dogs. J Cardiovasc Pharmacol. 27:1996;247-254.
22. Reller M.D., Burson M.A., Lohr J.L., Morton M.J., Thornburg K.L. Nitric oxide is an important determinant of coronary flow at rest and during hypoxemic stress in fetal lambs. Am J Physiol. 269:1995;H2074-H2081.
23. Okamura T., Ayajiki K., Toda N. Neural mechanisms of pressor action of nitric oxide synthase inhibitor in anesthetized monkeys. Hypertension. 28:1996;341-346.
24. Yoshida K., Okamura H., Kimura H., Bredt D.S., Snyder S.H., Toda N. Nitric oxide synthase-immunoreactive nerve fibers in dog cerebral and peripheral arteries. Brain Res. 629:1993;67-72.
25. Hock C.E., Yin K., Yue G., Wong P.Y. Effects of inhibition of nitric oxide synthase by aminoguanidine in acute endotoxemia. Am J Physiol. 272:1997;H843-850.