메뉴 건너뛰기




Volumn 56, Issue 1, 1999, Pages 185-195

The staurosporine-like compound L-753,000 (NB-506) potentiates the neurotrophic effects of neurotrophin-3 by acting selectively at the TrkA receptor

Author keywords

[No Author keywords available]

Indexed keywords

6 FORMYLAMINO 12,13 DIHYDRO 1,11 DIHYDROXY 5H INDOLO[2,3 A][PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE 13 GLUCOSIDE; K 252B; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN 3; PROTEIN KINASE INHIBITOR; STAUROSPORINE; TYROSINE KINASE RECEPTOR;

EID: 0033057286     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.1.185     Document Type: Article
Times cited : (32)

References (35)
  • 1
    • 0028905348 scopus 로고
    • Novel indolocarbazole compound 6-N-formylamino-12, 13-dihydro-1, 11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo [2,3-α] pyrrolo [3,4-c]carbazole-5,7(6H)-dione (NB-506): Its potent antitumor activities in mice
    • Arakawa H, Iguchi T, Morita M, Yoshinari T, Kojiri K, Suda H, Okura A and Nishimura S (1995) Novel indolocarbazole compound 6-N-formylamino-12, 13-dihydro-1, 11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo [2,3-α] pyrrolo [3,4-c]carbazole-5,7(6H)-dione (NB-506): Its potent antitumor activities in mice. Cancer Res 55:1316-1320.
    • (1995) Cancer Res , vol.55 , pp. 1316-1320
    • Arakawa, H.1    Iguchi, T.2    Morita, M.3    Yoshinari, T.4    Kojiri, K.5    Suda, H.6    Okura, A.7    Nishimura, S.8
  • 2
    • 0028090302 scopus 로고
    • The Trk family of neurotrophin receptors
    • Barbacid M (1994) The Trk family of neurotrophin receptors. J Neurobiol 25:1386-1403.
    • (1994) J Neurobiol , vol.25 , pp. 1386-1403
    • Barbacid, M.1
  • 4
    • 0027183950 scopus 로고
    • Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness
    • Benedetti M, Levi A and Chao MV (1993) Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness. Proc Natl Acad Sci USA 90:7859-7863.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7859-7863
    • Benedetti, M.1    Levi, A.2    Chao, M.V.3
  • 5
    • 0026512998 scopus 로고
    • K-252a inhibits nerve growth factor-induced Trk proto-oncogene tyrosine phosphorylation and kinase activity
    • Berg MM, Sternberg DW, Parada LF and Chao MV (1992) K-252a inhibits nerve growth factor-induced Trk proto-oncogene tyrosine phosphorylation and kinase activity. J Biol Chem 267:13-16.
    • (1992) J Biol Chem , vol.267 , pp. 13-16
    • Berg, M.M.1    Sternberg, D.W.2    Parada, L.F.3    Chao, M.V.4
  • 6
    • 0032730351 scopus 로고    scopus 로고
    • A rapid method for semi-quantitative analysis of neunte outgrowth from primary cultures of chick DRG expiants using image analysis
    • in press
    • Bilsland JG, Rigby M, Young L and Harper SJ (1999) A rapid method for semi-quantitative analysis of neunte outgrowth from primary cultures of chick DRG expiants using image analysis. J Neurosci Methods, in press.
    • (1999) J Neurosci Methods
    • Bilsland, J.G.1    Rigby, M.2    Young, L.3    Harper, S.J.4
  • 7
    • 0025190264 scopus 로고
    • Differential effects of the protein kinase inhibitor K-252a on the in vitro survival of chick embryonic neurons
    • Borasio GD (1990) Differential effects of the protein kinase inhibitor K-252a on the in vitro survival of chick embryonic neurons. Neurosci Lett 108:207-212.
    • (1990) Neurosci Lett , vol.108 , pp. 207-212
    • Borasio, G.D.1
  • 8
    • 0000854861 scopus 로고
    • Growth of a rat neuroblastoma cell line in serum-free supplemented medium
    • Bottenstein JE and Sato GH (1979) Growth of a rat neuroblastoma cell line in serum-free supplemented medium. Proc Natl Acad Sci USA 76:514-517.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 514-517
    • Bottenstein, J.E.1    Sato, G.H.2
  • 9
    • 0029021457 scopus 로고
    • P75 and Trk: A two-receptor system
    • Chao MV and Hempstead BL (1995) p75 and Trk: A two-receptor system. Trends Neurosci 18:321-326.
    • (1995) Trends Neurosci , vol.18 , pp. 321-326
    • Chao, M.V.1    Hempstead, B.L.2
  • 10
    • 0032102110 scopus 로고    scopus 로고
    • The role of neuronal growth factors in neurode-generative disorders of the human brain
    • Connor B and Dragunow M (1998) The role of neuronal growth factors in neurode-generative disorders of the human brain. Brain Res Rev 27:1-39.
    • (1998) Brain Res Rev , vol.27 , pp. 1-39
    • Connor, B.1    Dragunow, M.2
  • 11
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • Cowley S, Paterson H, Kemp P, Marshall CJ (1984) Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77:841-852.
    • (1984) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 12
    • 0028808732 scopus 로고
    • Early events in neurotrophin signalling via Trk and p75 receptors
    • Greene LA and Kaplan DR (1995) Early events in neurotrophin signalling via Trk and p75 receptors. Curr Opin Neurobiol 5:579-587.
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 579-587
    • Greene, L.A.1    Kaplan, D.R.2
  • 14
    • 0027969199 scopus 로고
    • EGF induces PC12 cell differentiation in the presence of the protein kinase inhibitor K-252a
    • Isono F, Widmer HR, Hefti F and Knüsel B (1994) EGF induces PC12 cell differentiation in the presence of the protein kinase inhibitor K-252a. J Neurochem 63:1235-1245.
    • (1994) J Neurochem , vol.63 , pp. 1235-1245
    • Isono, F.1    Widmer, H.R.2    Hefti, F.3    Knüsel, B.4
  • 15
    • 0031772820 scopus 로고    scopus 로고
    • Studying signal transduction in neuronal cells: The Trk/NGF system
    • Kaplan DR (1998) Studying signal transduction in neuronal cells: The Trk/NGF system. Prog Brain Res 117:35-46.
    • (1998) Prog Brain Res , vol.117 , pp. 35-46
    • Kaplan, D.R.1
  • 17
    • 0026595294 scopus 로고
    • K-252 compounds: Modulators of neurotrophin signal transduction
    • Knüsel B and Hefti FF (1992) K-252 compounds: Modulators of neurotrophin signal transduction. J Neurochem 59:1987-1996.
    • (1992) J Neurochem , vol.59 , pp. 1987-1996
    • Knüsel, B.1    Hefti, F.F.2
  • 20
    • 0028196552 scopus 로고
    • p75 deficient embryonic dorsal root sensory and neunatal sympathetic neurons display a decreased sensitivity to NGF
    • Lee K-F, Davies AM and Jaenisch R (1994) p75 deficient embryonic dorsal root sensory and neunatal sympathetic neurons display a decreased sensitivity to NGF. Development 120:1027-1033.
    • (1994) Development , vol.120 , pp. 1027-1033
    • Lee, K.-F.1    Davies, A.M.2    Jaenisch, R.3
  • 21
    • 0028870428 scopus 로고
    • K-252a induces tyrosine phosphorylation of the focal adhesion kinase and neurite outgrowth in human neuroblastoma SH-SY5Y cells
    • Maroney AC, Lipfert L, Forbes ME, Glicksman MA, Neff NT, Siman R, Dionne CA (1995) K-252a induces tyrosine phosphorylation of the focal adhesion kinase and neurite outgrowth in human neuroblastoma SH-SY5Y cells. J Neurochem 64:540-549.
    • (1995) J Neurochem , vol.64 , pp. 540-549
    • Maroney, A.C.1    Lipfert, L.2    Forbes, M.E.3    Glicksman, M.A.4    Neff, N.T.5    Siman, R.6    Dionne, C.A.7
  • 23
    • 0023932343 scopus 로고
    • Inhibition by K-252a, a new inhibitor of protein kinase, of nerve growth factor-induced neurite outgrowth of chick embryo dorsal root ganglion cells
    • Matsuda Y and Fukuda J (1988) Inhibition by K-252a, a new inhibitor of protein kinase, of nerve growth factor-induced neurite outgrowth of chick embryo dorsal root ganglion cells. Neurosci Lett 87:295-301.
    • (1988) Neurosci Lett , vol.87 , pp. 295-301
    • Matsuda, Y.1    Fukuda, J.2
  • 24
    • 0028846039 scopus 로고
    • Peripheral neuropathies and neurotrophic factors: Animal models and clinical perspectives
    • McMahon SB and Priestly JV (1995) Peripheral neuropathies and neurotrophic factors: Animal models and clinical perspectives. Curr Opin Neurobiol 5:616-624.
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 616-624
    • McMahon, S.B.1    Priestly, J.V.2
  • 25
    • 0030997428 scopus 로고    scopus 로고
    • TrkB variants with deletions in the leucine-rich motifs of the extracellular domain
    • Ninkina N, Grashchuck M, Buchman VL and Davies AM (1997) TrkB variants with deletions in the leucine-rich motifs of the extracellular domain. J Biol Chem 272:13019-13025.
    • (1997) J Biol Chem , vol.272 , pp. 13019-13025
    • Ninkina, N.1    Grashchuck, M.2    Buchman, V.L.3    Davies, A.M.4
  • 27
    • 0026684676 scopus 로고
    • Inhibition of the cellular actions of nerve growth factor by staurosporine and K-252a results from the attenuation of the activity of the Trk tyrosine kinase
    • Ohmichi M and Decker SJ (1992) Inhibition of the cellular actions of nerve growth factor by staurosporine and K-252a results from the attenuation of the activity of the Trk tyrosine kinase. Biochemistry 31:4034-4039.
    • (1992) Biochemistry , vol.31 , pp. 4034-4039
    • Ohmichi, M.1    Decker, S.J.2
  • 28
    • 0003008910 scopus 로고    scopus 로고
    • Neurotrophin treatment of peripheral sensory neuropathies
    • (Hefti F ed) Springer, Berlin
    • Rask CA and Escandon E (1998) Neurotrophin treatment of peripheral sensory neuropathies, in Neurotrophic Factors: Handbook of Experimental Pharmacology (Hefti F ed) vol 134, pp 53-72, Springer, Berlin.
    • (1998) Neurotrophic Factors: Handbook of Experimental Pharmacology , vol.134 , pp. 53-72
    • Rask, C.A.1    Escandon, E.2
  • 30
    • 0029055577 scopus 로고
    • An immunoglobulin-like domain determines the specificity of neurotrophin receptors
    • Urfer R, Tsoulfas P, O'Connell L, Shelton, DL, Parada, LF and Presta LG (1995) An immunoglobulin-like domain determines the specificity of neurotrophin receptors. EMBO J 14:2795-2805.
    • (1995) EMBO J , vol.14 , pp. 2795-2805
    • Urfer, R.1    Tsoulfas, P.2    O'Connell, L.3    Shelton, D.L.4    Parada, L.F.5    Presta, L.G.6
  • 31
    • 0032489439 scopus 로고    scopus 로고
    • High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptors
    • Urfer R, Tsoulfas P, O'Connell L, Hongo J-A, Zhao W and Presta LG (1998) High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptors. J Biol Chem 273:5829-5840.
    • (1998) J Biol Chem , vol.273 , pp. 5829-5840
    • Urfer, R.1    Tsoulfas, P.2    O'Connell, L.3    Hongo, J.-A.4    Zhao, W.5    Presta, L.G.6
  • 32
    • 0028868483 scopus 로고
    • Specific neurotrophin binding to leucine-rich motif peptides of TrkA and TrkB
    • Windisch JM, Auer B, Marksteiner R, Lang ME and Schneider R (1995a) Specific neurotrophin binding to leucine-rich motif peptides of TrkA and TrkB. FEBS Lett 374:125-129.
    • (1995) FEBS Lett , vol.374 , pp. 125-129
    • Windisch, J.M.1    Auer, B.2    Marksteiner, R.3    Lang, M.E.4    Schneider, R.5
  • 33
    • 0028846967 scopus 로고
    • Nerve growth factor binding site on TrkA mapped to a single 24-amino acid leucine-rich motif
    • Windisch JM, Marksteiner R and Schneider R (1995b) Nerve growth factor binding site on TrkA mapped to a single 24-amino acid leucine-rich motif. J Biol Chem 1995:28133-28138.
    • (1995) J Biol Chem , vol.1995 , pp. 28133-28138
    • Windisch, J.M.1    Marksteiner, R.2    Schneider, R.3
  • 34
    • 0027360140 scopus 로고
    • K-252a potentiates epidermal growth factor-induced differentiation of PC12 cells
    • Wu C-F and Zhang M (1993) K-252a potentiates epidermal growth factor-induced differentiation of PC12 cells. J Neurosci Res 36:539-550.
    • (1993) J Neurosci Res , vol.36 , pp. 539-550
    • Wu, C.-F.1    Zhang, M.2
  • 35
    • 0028931509 scopus 로고
    • Novel antitumor indolocarbazole compound 6-N-formylamino-12, 13-dihydro-1, 11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-α]pyrrolo[3,4-c] carbazole-5,7(6H)-dione (NB-506): Induction of toppisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity
    • Yoshinari T, Matsumoto M, Arakawa H, Okada H, Noguchi K, Suda H, Okura A and Nishimura S (1995) Novel antitumor indolocarbazole compound 6-N-formylamino-12, 13-dihydro-1, 11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-α]pyrrolo[3,4-c] carbazole-5,7(6H)-dione (NB-506): Induction of toppisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity. Cancer Res 55:1310-1315.
    • (1995) Cancer Res , vol.55 , pp. 1310-1315
    • Yoshinari, T.1    Matsumoto, M.2    Arakawa, H.3    Okada, H.4    Noguchi, K.5    Suda, H.6    Okura, A.7    Nishimura, S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.