Modulation of ATP-responses at recombinant rP2X4 receptors by extracellular pH and zinc

British Journal of Pharmacology

Volumn 126, Issue 3, 1999, Pages 762-768

  Wildman, S S ^a,b   King, B F ^a,b   Burnstock, G ^a,b  

^a ROYAL FREE HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

ATP; Extracellular pH; P2X receptor; Xenopus oocyte; Zinc

Indexed keywords

ADENOSINE TRIPHOSPHATE; PURINE P2X RECEPTOR; SURAMIN; ZINC ION;

ANIMAL CELL; ARTICLE; FEMALE; NONHUMAN; OOCYTE; PH; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

EID: 0033056227     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702325     Document Type: Article

References (39)

1. 2+ from brain tissue during activity. Nature, 308, 734-736.
2. BARAJAS-LÓPEZ, C., HUIZINGA, J.D., COLLINS, S.M., GERZANICH, V., ESPINOZA-LUNA, R. & PERES, L.A. (1996). P2X-purinoceptors of myenteric neurones from the guinea-pig ileum and their unusual pharmacological properties. Brit. J. Pharmacol., 119, 1541-1548.
3. BARDONI, R., GOLDSTEIN, P.A., LEE, C.J., GU, J.G. & MACDERMOTT, A.B. (1997). ATP P2X receptors mediate fast synaptic transmission in the dorsal horn of the rat spinal cord. J. Neurosci., 17, 5297-5304.
4. BO, X., ZHANG, Y., NASSAR, M., BURNSTOCK, G. & SCHOEPFER, R. (1995). A P2X purinoceptor cDNA conferring a novel pharmacological profile. FEBS Lett., 375, 129-133.
5. BRAKE, A.J., WAGENBACH, M.J. & JULIUS, D. (1994). New structural motif for ligand gated ion channels defined by an ionotropic ATP receptor. Nature, 371, 519-523.
6. BROOKS, S.P.J. & STOREY, K.B. (1992). Bound and Determined: a computer program for making buffers of defined ion concentrations. Anal. Biochem., 210, 119-126.
7. BUELL, G., LEWIS, C., COLLO, G., NORTH, R.A. & SURPRENANT, A. (1996). An antagonist-insensitive P2X receptor expressed in epithelia and brain. EMBO J., 15, 55-62.
8. CHESLER, M. (1990). The regulation and modulation of pH in the nervous system. Prog. Neurobiol., 34, 401-427.
9. 4 receptors expressed in Xenopus oocytes. J. Physiol., 506, 44P.
10. 2+ potentiates ATP-activated currents in rat sympathetic neurons. Pflügers Arch., 424, 152-158.
11. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J. Neurosci., 16, 2495-2507.
12. DESALLES, A.A., KONTOS, H.A., WARD, J.B., MARMAROU, A. & BECKER, D.P. (1987). Brain tissue pH in severely head injured patients: a report of 3 cases. Neurosurgery, 20, 297-301.
13. 4 receptor gene is alternatively spliced. Gene, 207, 259-266.
14. EDWARDS, F.A., GIBB, A.J. & COLQUHOUN, D. (1992). ATP receptor-mediated synaptic currents in the central nervous system. Nature, 359, 144-147.
15. EVANS, R.J., DERKACH, V. & SURPRENANT, A. (1992). ATP mediates fast synaptic transmission in mammalian neurons. Nature, 357, 503-505.
16. GALLIGAN, J.J. & BERTRAND, P.P. (1994). ATP mediates fast synaptic potentials in enteric neurons. J. Neurosci., 14, 7563-7571.
17. 4 receptor reveals pharmacological differences to the rat homologue. Mol. Pharmacol., 51, 109-118.
18. JOHNSON, R.G. & SCARPA, A. (1976). Internal pH of isolated chromaffin granules. J. Biol. Chem., 251, 2189-2191.
19. 2 receptor. Brit. J. Pharmacol., 121, 1445-1453.
20. 2 purinoceptor to ATP revealed by changing extracellular pH. Brit. J. Pharmacol., 117, 1317-1373.
21. + channel involved in sperm-induced fertilization. Science, 261, 484-486.
22. LÊ, K.T., VILLENEUVE, P., RAMJAUN, A.R., MCPHERSON, P.S., BEADET, A. & SÉGUÉLA, P. (1998). Sensory presynaptic and widespread somatodendritic immunolocalization of central ionotropic P2X ATP receptors. Neurosci., 83, 177-190.
23. NAKAZAWA, K. & OHNO, Y. (1996). Dopamine and 5-hydroxytryptamine selectively potentiate neuronal type ATP receptor channels. Eur. J. Pharmacol., 296, 119-122.
24. NAKAZAWA, K. & OHNO, Y. (1997). Effects of neuroamines and divalent cations on cloned and mutated ATP-gated channels. Eur. J. Pharmacol., 325, 101-108.
25. NIEBER, K., POELCHEN, W. & ILLES, P. (1997). Role of ATP in fast excitatory synaptic potentials in locus ceuruleus neurones of the rat. Brit. J. Pharmacol., 122, 423-430.
26. NORTH, R.A. & BARNARD, E.A. (1997). Nucleotide receptors. Curr. Opin. Neurobiol., 7, 346-357.
27. RANSOM, B.R. & PHILBIN JR., D.M. (1992). Anoxia-induced extracellular ionic changes in the CNS white matter: the role of glial cells. Can. J. Physiol. Pharmacol., 70, S181-S189.
28. SÉGUÉLA, P., HAGHIGHI, A., SOGHOMONIAN, J. & COOPER, E. (1996). A novel neuronal P2X ATP receptor ion channel with widespread distribution in the brain. J. Neurosci., 16, 448-455.
29. SILINSKY, E.M. & GERZANICH, V. (1993). On the excitatory effects of ATP and its role as a neurotransmitter in coeliac neurons of the guinea-pig. J. Physiol., 464, 197-212.
30. 4: an ATP-activated ionotropic receptor cloned from rat brain. Proc. Natl. Acad. Sci. U.S.A., 93, 3684-3688.
31. SPERLAGH, B., KITTEL, A., LAJTHA, A. & VIZI, E.S. (1995). ATP acts as fast neurotransmitter in rat habenula: neurochemical and enzyme cytochemical evidence. Neurosci., 66, 915-920.
32. STEEN, K.H., REEH, P.W., ANTON, F. & HANDWERKER, H.O. (1992). Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociception in rat skin, in vitro. J. Neurosci., 12, 86-95.
33. STOOP, R., SURPRENANT, A. & NORTH, R.A. (1997). Different sensitivities to pH of ATP-induced currents at four cloned P2X receptors. J. Neurophysiol., 78, 1837-1840.
34. URANO, T., NISHIMORI, H., HAN, H.J., FURUHATA, T., KIMURA, Y., NAKAMURA, Y. & TOKINO, T. (1997). Cloning of P2XM, a novel human P2X receptor gene regulated by p53. Cancer Res., 57, 3281-3287.
35. WANG, C.Z., NAMBA, N., GONOI, T., INAGAKI, N. & SEINO, S. (1996). Cloning and pharmacological characterization of a fourth P2X subtype widely expressed in brain and peripheral tissues including various endocrine tissues. Biochem. Biophys. Res. Comm., 220, 196-202.
36. 2 receptor by neurotransmitters and related substances. Brit. J. Pharmacol., 120, 221-224.
37. 2 receptors and its dependence on extracellular pH. Brit. J. Pharmacol., 123, 1214-1220.
38. YANOVSKY, Y., REYMANN, K. & HAAS, H.L. (1995). pH-dependent facilitation of synaptic transmission by histamine in the CA1 region of mouse hippocampus. Eur. J. Neurosci., 7, 2017-2020.
39. ZHOU, X. & GALLIGAN, J.J. (1996). P2X purinoceptor in cultured myenteric neurons of guinea-pig small intestine. J. Physiol., 496, 719-729.