메뉴 건너뛰기




Volumn 17, Issue 7, 1999, Pages 670-675

Antibodies engineered with IgD specificity efficiently deliver integrated T-cell epitopes for antigen presentation by B cells

Author keywords

Antigen processing; Immunization; MHC class II; Recombinant immunoglobulin; Vaccination

Indexed keywords

EPITOPE; IMMUNOGLOBULIN; IMMUNOGLOBULIN D; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 0033051777     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/10883     Document Type: Article
Times cited : (51)

References (41)
  • 2
    • 0023200632 scopus 로고
    • Targeted antigen presentation using crosslinked antibody heteroaggregates
    • Snider, D.P. & Segal, D.M. Targeted antigen presentation using crosslinked antibody heteroaggregates. J. Immunol. 139, 1609-1616 ((1987).
    • (1987) J. Immunol. , vol.139 , pp. 1609-1616
    • Snider, D.P.1    Segal, D.M.2
  • 3
    • 0022638799 scopus 로고
    • Enhancement of antigenic potency in vitro and immunogenicity in vivo by coupling the antigen to anti-immunoglobulin
    • Kawamura, H. & Berzofsky, J.A. Enhancement of antigenic potency in vitro and immunogenicity in vivo by coupling the antigen to anti-immunoglobulin. J. Immunol. 136, 58-65 (1986).
    • (1986) J. Immunol. , vol.136 , pp. 58-65
    • Kawamura, H.1    Berzofsky, J.A.2
  • 4
    • 2642614881 scopus 로고
    • Receptor-mediated B cell antigen processing. Increased antigenicity of a globular protein covalently coupled to antibodies specific for B cell surface structures
    • Casten, L.A. & Pierce, S.K. Receptor-mediated B cell antigen processing. Increased antigenicity of a globular protein covalently coupled to antibodies specific for B cell surface structures. J. Immunol. 140, 404-410 (1988).
    • (1988) J. Immunol. , vol.140 , pp. 404-410
    • Casten, L.A.1    Pierce, S.K.2
  • 5
    • 0025201735 scopus 로고
    • Rapid stimulation of large specific antibody responses with conjugates of antigen and anti-IgD antibody
    • Lees, A., Morris, S.C., Thyphronitis, G., Holmes, J.M., Inman, J.K., & Finkelman, F.D. Rapid stimulation of large specific antibody responses with conjugates of antigen and anti-IgD antibody. J. Immunol. 145, 3594-3600 (1990).
    • (1990) J. Immunol. , vol.145 , pp. 3594-3600
    • Lees, A.1    Morris, S.C.2    Thyphronitis, G.3    Holmes, J.M.4    Inman, J.K.5    Finkelman, F.D.6
  • 6
    • 0023032941 scopus 로고
    • Idiotope-specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules
    • Bogen, B., Malissen, B., & Haas, W. Idiotope-specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules. Eur. J. Immunol. 16, 1373-1378 (1986).
    • (1986) Eur. J. Immunol. , vol.16 , pp. 1373-1378
    • Bogen, B.1    Malissen, B.2    Haas, W.3
  • 7
    • 0023897315 scopus 로고
    • T cell recognition of endogenous IgG2a expressed in B lymphoma cells
    • Bikoff, E.K., Yu, H., & Eckhardt, L.A. T cell recognition of endogenous IgG2a expressed in B lymphoma cells. Eur. J. Immunol. 18, 341-348 (1988).
    • (1988) Eur. J. Immunol. , vol.18 , pp. 341-348
    • Bikoff, E.K.1    Yu, H.2    Eckhardt, L.A.3
  • 8
    • 0027398099 scopus 로고
    • Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecule
    • Zaghouani, H., Steinman, R., Nonacs, R., Shah, H., Gerhard, W., & Bona, C. Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecule. Science 259, 224-227 (1993).
    • (1993) Science , vol.259 , pp. 224-227
    • Zaghouani, H.1    Steinman, R.2    Nonacs, R.3    Shah, H.4    Gerhard, W.5    Bona, C.6
  • 9
    • 0028949255 scopus 로고
    • Immunogenic targeting of recombinant peptide vaccines to human antigen-presenting cells by chimeric anti-HLA-DR and anti-surface immunoglobulin D antibody Fab fragments in vitro
    • Baier, G., Baier-Bitterlich, G., Looney, D.J., & Altman, A. Immunogenic targeting of recombinant peptide vaccines to human antigen-presenting cells by chimeric anti-HLA-DR and anti-surface immunoglobulin D antibody Fab fragments in vitro. J. Virol. 69, 2357-2365 (1995).
    • (1995) J. Virol. , vol.69 , pp. 2357-2365
    • Baier, G.1    Baier-Bitterlich, G.2    Looney, D.J.3    Altman, A.4
  • 10
    • 0344157386 scopus 로고    scopus 로고
    • Immunoglobulin as a vehicle for foreign antigenic peptides immunogenic to T cells
    • Lunde, E., Bogen, B., & Sandlie, I. Immunoglobulin as a vehicle for foreign antigenic peptides immunogenic to T cells. Mol. Immunol. 34, 1167-1176 (1997).
    • (1997) Mol. Immunol. , vol.34 , pp. 1167-1176
    • Lunde, E.1    Bogen, B.2    Sandlie, I.3
  • 11
    • 0342353841 scopus 로고
    • Assessment of antigen-specific receptor function of surface immunoglobulin M and D with identical hapten specificity
    • Tisch, R., Watanabe, M., Letarte, M., & Hozumi, N. Assessment of antigen-specific receptor function of surface immunoglobulin M and D with identical hapten specificity. Proc. Natl. Acad. Sci. USA 84, 3831-3835 (1987).
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 3831-3835
    • Tisch, R.1    Watanabe, M.2    Letarte, M.3    Hozumi, N.4
  • 12
    • 0029129468 scopus 로고
    • Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: Evidence that the protective mechanism depends on changes in the cytokine response and migratory properties of the autoantigen-specific T cells
    • Saoudi, A., Simmonds, S., Huitinga, I., & Mason, D. Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: evidence that the protective mechanism depends on changes in the cytokine response and migratory properties of the autoantigen-specific T cells. J. Exp. Med. 182, 335-344 (1995).
    • (1995) J. Exp. Med. , vol.182 , pp. 335-344
    • Saoudi, A.1    Simmonds, S.2    Huitinga, I.3    Mason, D.4
  • 13
    • 0024407491 scopus 로고
    • Efficiency of antigen presentation after antigen targeting to surface IgD, IgM, MHC, Fc gamma RII, and B220 molecules on murine splenic B cells
    • Snider, D.P. & Segal, D.M. Efficiency of antigen presentation after antigen targeting to surface IgD, IgM, MHC, Fc gamma RII, and B220 molecules on murine splenic B cells. J. Immunol. 143, 59-65 (1989).
    • (1989) J. Immunol. , vol.143 , pp. 59-65
    • Snider, D.P.1    Segal, D.M.2
  • 14
    • 0023018931 scopus 로고
    • Synthetic peptides and beta-chain gene rearrangements reveal a diversified T cell repertoire for a lambda light chain third hypervariable region
    • Bogen, B., Snodgrass, R., Briand, J.P., & Hannestad, K. Synthetic peptides and beta-chain gene rearrangements reveal a diversified T cell repertoire for a lambda light chain third hypervariable region. Eur. J. Immunol. 16, 1379-1384 (1986).
    • (1986) Eur. J. Immunol. , vol.16 , pp. 1379-1384
    • Bogen, B.1    Snodgrass, R.2    Briand, J.P.3    Hannestad, K.4
  • 15
    • 0024469007 scopus 로고
    • Minimum length of an idiotypic peptide and a model for its binding to a major histocompatibility complex class II molecule
    • Bogen, B. & Lambris, J.D. Minimum length of an idiotypic peptide and a model for its binding to a major histocompatibility complex class II molecule. EMBO J. 8, 1947-1952 (1989).
    • (1989) EMBO J. , vol.8 , pp. 1947-1952
    • Bogen, B.1    Lambris, J.D.2
  • 16
    • 0018575887 scopus 로고
    • Localization of murine Ig-1b and Ig-1a (IgG 2a) allotypic determinants detected with monoclonal antibodies
    • Oi, V.T. & Herzenberg, L.A. Localization of murine Ig-1b and Ig-1a (IgG 2a) allotypic determinants detected with monoclonal antibodies. Mol. Immunol. 16, 1005-1017 (1979).
    • (1979) Mol. Immunol. , vol.16 , pp. 1005-1017
    • Oi, V.T.1    Herzenberg, L.A.2
  • 17
    • 0018073601 scopus 로고
    • Genetics of Ig CH (allotype) locus in the mouse
    • Lieberman, R. Genetics of Ig CH (allotype) locus in the mouse. Sem. Immunopathol. 1, 7 (1978).
    • (1978) Sem. Immunopathol. , vol.1 , pp. 7
    • Lieberman, R.1
  • 18
    • 0026586688 scopus 로고
    • Weak positive selection of transgenic T cell receptor-bearing thymocytes: Importance of major histocompatibility complex class II, T cell receptor and CD4 surface molecule densities
    • Bogen, B., Gleditsch, L., Weiss, S., & Dembic, Z. Weak positive selection of transgenic T cell receptor-bearing thymocytes: importance of major histocompatibility complex class II, T cell receptor and CD4 surface molecule densities. Eur. J. Immunol. 22, 703-709 (1992).
    • (1992) Eur. J. Immunol. , vol.22 , pp. 703-709
    • Bogen, B.1    Gleditsch, L.2    Weiss, S.3    Dembic, Z.4
  • 19
    • 0025175090 scopus 로고
    • A stimulatory monoclonal antibody detecting T cell receptor diversity among idiotype-specific, major histocompatibility complex-restricted T cell clones
    • Bogen, B., Lauritzsen, G.F., & Weiss, S. A stimulatory monoclonal antibody detecting T cell receptor diversity among idiotype-specific, major histocompatibility complex-restricted T cell clones. Eur. J. Immunol. 20, 2359-2362 (1990).
    • (1990) Eur. J. Immunol. , vol.20 , pp. 2359-2362
    • Bogen, B.1    Lauritzsen, G.F.2    Weiss, S.3
  • 20
    • 0030828486 scopus 로고    scopus 로고
    • Engineering vaccines with heterologous B and T cell epitopes using immunoglobulin genes
    • Xiong, S., Gerloni, M., & Zanetti, M. Engineering vaccines with heterologous B and T cell epitopes using immunoglobulin genes. Nat. Biotechnol. 15, 882-886 (1997).
    • (1997) Nat. Biotechnol. , vol.15 , pp. 882-886
    • Xiong, S.1    Gerloni, M.2    Zanetti, M.3
  • 21
    • 0002800589 scopus 로고
    • Immunogenicity of microbial peptides grafted in self immunoglobulin molecules
    • Bona, C., Brumeanu, T.D., & Zaghouani, H. Immunogenicity of microbial peptides grafted in self immunoglobulin molecules. [Review]. Cell. Mol. Biol. 40 (Suppl 1), 21-30 (1994).
    • (1994) Cell. Mol. Biol. , vol.40 , Issue.SUPPL. 1 , pp. 21-30
    • Bona, C.1    Brumeanu, T.D.2    Zaghouani, H.3
  • 22
    • 0030865220 scopus 로고    scopus 로고
    • Immunity to Plasmodium falciparum malaria sporozoites by somatic transgene immunization
    • Gerloni, M., Baliou, W.R., Billetta, R., & Zanetti, M. Immunity to Plasmodium falciparum malaria sporozoites by somatic transgene immunization. Nat. Biotechnol. 15, 876-881 (1997).
    • (1997) Nat. Biotechnol. , vol.15 , pp. 876-881
    • Gerloni, M.1    Baliou, W.R.2    Billetta, R.3    Zanetti, M.4
  • 24
    • 0027373035 scopus 로고
    • Studies on naturally processed peptides associated with MHC class II molecules
    • Rudensky, A. & Janeway, C.A. Jr., Studies on naturally processed peptides associated with MHC class II molecules. Chem. Immunol. 57, 134-151 (1993).
    • (1993) Chem. Immunol. , vol.57 , pp. 134-151
    • Rudensky, A.1    Janeway C.A., Jr.2
  • 25
    • 0026664454 scopus 로고
    • Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad
    • Hunt, D.F. et al. Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad. Science 256, 1817-1820 (1992).
    • (1992) Science , vol.256 , pp. 1817-1820
    • Hunt, D.F.1
  • 26
    • 0027181070 scopus 로고
    • Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles
    • Chicz, R.M., Urban, R.G., Gorga, J.C., Vignali, D.A., Lane, W.S., & Strominger, J.L. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J. Exp. Med. 178, 27-47 (1993).
    • (1993) J. Exp. Med. , vol.178 , pp. 27-47
    • Chicz, R.M.1    Urban, R.G.2    Gorga, J.C.3    Vignali, D.A.4    Lane, W.S.5    Strominger, J.L.6
  • 27
    • 0029906983 scopus 로고    scopus 로고
    • Peripheral T cell tolerance as a tumor escape mechanism: Deletion of CD4+ T cells specific for a monoclonal immunoglobulin idiotype secreted by a plasmacytoma
    • Bogen, B. Peripheral T cell tolerance as a tumor escape mechanism: deletion of CD4+ T cells specific for a monoclonal immunoglobulin idiotype secreted by a plasmacytoma. Eur. J. Immunol. 26, 2671-2679 (1996).
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2671-2679
    • Bogen, B.1
  • 28
    • 0025819491 scopus 로고
    • Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations
    • Gajewski, T.F., Pinnas, M., Wong, T., & Fitch, F.W. Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations. J. Immunol. 146, 1750-1753 (1991).
    • (1991) J. Immunol. , vol.146 , pp. 1750-1753
    • Gajewski, T.F.1    Pinnas, M.2    Wong, T.3    Fitch, F.W.4
  • 29
    • 0025029064 scopus 로고
    • Heterogeneity of helper/inducer T lymphocytes. III. Responses of IL-2- and IL-4-producing (Th1 and Th2) clones to antigens presented by different accessory cells
    • Chang, T.L., Shea, C.M., Urioste, S., Thompson, R.C., Boom, W.H., & Abbas, A.K. Heterogeneity of helper/inducer T lymphocytes. III. Responses of IL-2- and IL-4-producing (Th1 and Th2) clones to antigens presented by different accessory cells. J. Immunol. 145, 2803-2808 (1990).
    • (1990) J. Immunol. , vol.145 , pp. 2803-2808
    • Chang, T.L.1    Shea, C.M.2    Urioste, S.3    Thompson, R.C.4    Boom, W.H.5    Abbas, A.K.6
  • 30
    • 0028209271 scopus 로고
    • Antigen presentation is enhanced by targeting antigen to the Fc epsilon RII by antigen-anti-Fc epsilon RII conjugates
    • Squire, C.M., Studer, E.J., Lees, A., Finkelman, F.D., & Conrad, D.H. Antigen presentation is enhanced by targeting antigen to the Fc epsilon RII by antigen-anti-Fc epsilon RII conjugates. J. Immunol. 152, 4388-4396 (1994).
    • (1994) J. Immunol. , vol.152 , pp. 4388-4396
    • Squire, C.M.1    Studer, E.J.2    Lees, A.3    Finkelman, F.D.4    Conrad, D.H.5
  • 31
    • 0028979072 scopus 로고
    • Membrane and soluble Fc gamma RII/III modulate the antigen-presenting capacity of murine dendritic epidermal Langerhans cells for IgG- complexed antigens
    • Esposito-Faresa, M.E. et al. Membrane and soluble Fc gamma RII/III modulate the antigen-presenting capacity of murine dendritic epidermal Langerhans cells for IgG- complexed antigens. J. Immunol. 155, 1725-1736 (1995).
    • (1995) J. Immunol. , vol.155 , pp. 1725-1736
    • Esposito-Faresa, M.E.1
  • 32
    • 0029009977 scopus 로고
    • The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
    • Jiang, W. et al. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375, 151-155 (1995).
    • (1995) Nature , vol.375 , pp. 151-155
    • Jiang, W.1
  • 33
    • 0026692077 scopus 로고
    • Restricted alpha/beta receptor gene usage of idiotype-specific major histocompatibility complex-restricted T cells: Selection for CDR3-related sequences
    • Snodgrass, H.R., Fisher, A.M., Bruyns, E., & Bogen, B. Restricted alpha/beta receptor gene usage of idiotype-specific major histocompatibility complex-restricted T cells: selection for CDR3-related sequences. Eur. J. Immunol. 22, 2169-2172 (1992).
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2169-2172
    • Snodgrass, H.R.1    Fisher, A.M.2    Bruyns, E.3    Bogen, B.4
  • 34
    • 0030972407 scopus 로고    scopus 로고
    • Versatile vectors for transient and stable expression of recombinant antibody molecules in mammalian cells
    • Norderhaug, L., Olafsen, T., Michaelsen, T.E., & Sandlie, I. Versatile vectors for transient and stable expression of recombinant antibody molecules in mammalian cells. J. Immunol. Methods 204, 77-67 (1997).
    • (1997) J. Immunol. Methods , vol.204 , pp. 77-167
    • Norderhaug, L.1    Olafsen, T.2    Michaelsen, T.E.3    Sandlie, I.4
  • 35
    • 0022623585 scopus 로고
    • Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: Comparison with the other human C gamma genes
    • Huck, S., Fort, P., Crawford, D.H., Lefranc, M.P., & Lefranc, G. Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human C gamma genes. Nucleic Acids Res. 14, 1779-1789 (1986).
    • (1986) Nucleic Acids Res. , vol.14 , pp. 1779-1789
    • Huck, S.1    Fort, P.2    Crawford, D.H.3    Lefranc, M.P.4    Lefranc, G.5
  • 36
    • 0024535530 scopus 로고
    • Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors
    • Kubo, R.T., Born, W., Kappler, J.W., Marrack, P., & Pigeon, M. Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J. Immunol. 142, 2736-2742 (1989).
    • (1989) J. Immunol. , vol.142 , pp. 2736-2742
    • Kubo, R.T.1    Born, W.2    Kappler, J.W.3    Marrack, P.4    Pigeon, M.5
  • 37
    • 0018971611 scopus 로고
    • Effects of cytotoxic monoclonal antibody specific for T200 glycoprotein on functional lymphoid cell populations
    • 1980
    • Dennert, G., Hyman, R., Lesley, J., & Trowbridge, I.S. (1980). Effects of cytotoxic monoclonal antibody specific for T200 glycoprotein on functional lymphoid cell populations. Cell Immunol. 53, 350-364 (1989).
    • (1989) Cell Immunol. , vol.53 , pp. 350-364
    • Dennert, G.1    Hyman, R.2    Lesley, J.3    Trowbridge, I.S.4
  • 38
    • 0028947581 scopus 로고
    • Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway
    • Lucas, B., Vasseur, F., & Penit, C. Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway. J. Exp. Med. 181, 1623-1633 (1995).
    • (1995) J. Exp. Med. , vol.181 , pp. 1623-1633
    • Lucas, B.1    Vasseur, F.2    Penit, C.3
  • 39
    • 0030585533 scopus 로고    scopus 로고
    • T cells with two Tcrbeta chains and reactivity to both MHC/idiotypic peptide and superantigen
    • Munthe, L.A., Blichfeldt, E., Sollien, A., Dembic, Z., & Bogen, B. T cells with two Tcrbeta chains and reactivity to both MHC/idiotypic peptide and superantigen. Cell Immunol. 170, 283-290 (1996).
    • (1996) Cell Immunol. , vol.170 , pp. 283-290
    • Munthe, L.A.1    Blichfeldt, E.2    Sollien, A.3    Dembic, Z.4    Bogen, B.5
  • 40
    • 0021348252 scopus 로고
    • Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation
    • Ashwell, J.D., DeFranco, A.L., Paul, W.E., & Schwartz, R.H. Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation. J. Exp. Med. 159, 881-905 (1984).
    • (1984) J. Exp. Med. , vol.159 , pp. 881-905
    • Ashwell, J.D.1    DeFranco, A.L.2    Paul, W.E.3    Schwartz, R.H.4
  • 41
    • 0025828217 scopus 로고
    • Idiotype-specific, major histocompatibility complex restricted T cells are of both Th1 and Th2 type
    • Lauritzsen, G.F. & Bogen, B. Idiotype-specific, major histocompatibility complex restricted T cells are of both Th1 and Th2 type. Scand. J. Immunol. 33, 647-656 (1991).
    • (1991) Scand. J. Immunol. , vol.33 , pp. 647-656
    • Lauritzsen, G.F.1    Bogen, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.